019Tilt Table Test Outcome in the Diagnosis and Prevalence of Syncope in Patients with Vitamin D and Vitamin B12 Deficiency

Background: In this study, the aim was to evaluate the prevalence of vitamin D, vitamin B12, ferritin, and folate deficiencies in adolescence to clarify the need for early diagnosis and therapy. Methods: The medical records of adolescents between 10 and 18 years of age between 01 September 2018 and 28 February 2019 as healthy with non-specific complaints, or due to well-child care visits, were analyzed retrospectively. Results: A total of 1847/2507 (73.6%) adolescents were included in the study. The prevalence of vitamin D deficiency was 25.7% (n: 178/691). Vitamin B12 deficiency prevalence was 69.2% (n: 753/1088). The prevalence of anemia and ferritin deficiency was 4.8% and 13.26%. The prevalence of folate deficiency was 37.9% (n: 413/1088). VDD prevalence was statistically significantly higher in females than males (F/M:116/62). VB12D prevalence, the number and mean age of females with hemoglobin deficiency, and low ferritin levels was found to be statistically significantly higher in females than males. Conclusions: The prevalence of vitamin D, vitamin B12, folate deficiency and low ferritin levels was found to be high among adolescents. In particular, adolescents admitting with non-specific complaints and for control purposes in big cities must be considered to be at risk for the deficiency of these vitamins and low level of ferritin.

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VITAMIN D DEFICIENCY RICKETS AND VITAMIN B12 DEFICIENCY IN VEGETARIAN CHILDREN

Journal of Pediatric Orthopaedics ◽

10.1097/01241398-198509000-00122 ◽

1985 ◽

Vol 5 (5) ◽

pp. 626

Author(s):

M. Helle-bostad ◽

T. Markestad ◽

K. S. Halvorsen

Keyword(s):

Vitamin D ◽

Vitamin B12 ◽

Vitamin D Deficiency ◽

Vitamin B12 Deficiency ◽

B12 Deficiency ◽

Deficiency Rickets

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Prevalence of vitamin D and B12 deficiency in pregnant women in Jammu, India

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20201083 ◽

2020 ◽

Vol 8 (4) ◽

pp. 1245

Author(s):

Sapneet Kaur ◽

Harleen Kaur

Keyword(s):

Vitamin D ◽

Vitamin B12 ◽

Pregnant Women ◽

Tertiary Care ◽

Vitamin B12 Deficiency ◽

Care Hospital ◽

Jammu And Kashmir ◽

Vitamin D Levels ◽

Good Nutrition ◽

B12 Deficiency

Background: Micronutrient deficiency is pandemic proportions among pregnant women in India, but there is scarcity of searchable data on coexistence vitamin D status and Vitamin B 12 in pregnant women in Jammu and Kashmir, hence we have assessed the vitamin D as well as Vitamin B12 status in pregnant women attending outpatient department in a tertiary care hospital Jammu.Methods: The study was conducted in the department of Biochemistry Government Medical College Jammu during June 2019 to February, 2020 and after obtaining informed consent, a total of 150 pregnant women, attending SMGS Hospital Jammu were screened for their vitamin D (25 OH-D) and vitamin B12 status by using Abbott architect chemiluminescent micro particle immunoassay.Results: A total of 150 pregnant women were screened in the study , 129 (86%) were found to be having insufficient vitamin D levels in their blood (<30 ngm/dl) and 105 ( 70%) women showed severe deficiency with vitamin D levels below 20 ngm/dl.108 (72%) pregnant women had vitamin B12 deficiency with levels below 200 pgm/ml.Conclusions: The study revealed a high prevalence of coexistence of Vitamin D and Vitamin B12 deficiency in pregnant women, despite of abundant sunshine throughout the year and also with the consideration that people of this region are well off economically and can afford good nutrition.

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Neurobiology of Increase in Violence in Pakistan and the Role of Online Medical Care in its Reduction

Journal of Clinical Review & Case Reports ◽

10.33140/jcrc.04.02.02 ◽

2019 ◽

Vol 4 (2) ◽

Keyword(s):

Vitamin D ◽

Vitamin B12 ◽

Medical Care ◽

Urban Areas ◽

Violent Behavior ◽

Vitamin B12 Deficiency ◽

Medical Care System ◽

B12 Deficiency ◽

On Line ◽

Care System

Causes of increase in violence in a named society, apart from socio-political and economical reasons, will be examined in this study. One of the most important reasons for increase in levels of hostility in a society is prevalence of psychological depression among population, which can lead to violent behavior and cause physical harm to one or others, increase in suicidal tendencies and destruction of property. Increase and prevalence of internal medical diseases are one of the main causes of increase in depression, among which diabetes, hypothyroidism, vitamin D, calcium, and vitamin B12 deficiency, hypo and dyslipidemia can be mentioned. The main cause for increasing prevalence of depression in Pakistan can be attributed to: -Rapid increase in spread of diabetes (mean prevalence13.14%), which increased 2 times in during 7 years period. Share of other illnesses contributing to depression can be summarized as follows, 20% to spread of diabetes in urban areas. - 6.6% to spread of vitamin B12 deficiency - 84.3% to spread of vitamin D deficiency - 8.29% of subclinical hypothyroidism In order to have more accurate results further measurements of prevalence of functional vitamin B12 deficiency and calcium is recommended. By using on line medical care system in Iran, it was found that 85% of people suffering from depression had at least one of the above mentioned causes, and after treatment symptoms of depression were noticeably reduced. At the end of this article there is an announcement for specialists in Pakistan and other countries to adapt the online medical care system to their own circumstances.

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Inflammatory Markers: C-Reactive Protein, Erythrocyte Sedimentation Rate, and Leukocyte Count in Vitamin D Deficient Patients with and without Chronic Kidney Disease

International Journal of Endocrinology ◽

10.1155/2013/802165 ◽

2013 ◽

Vol 2013 ◽

pp. 1-6 ◽

Cited By ~ 10

Author(s):

Ibrahim Yildirim ◽

Ender Hur ◽

Furuzan Kokturk

Keyword(s):

Chronic Kidney Disease ◽

Vitamin D ◽

Renal Failure ◽

Kidney Disease ◽

Vitamin B12 ◽

Inflammatory Markers ◽

Vitamin B12 Deficiency ◽

Reactive Protein ◽

25 Hydroxy Vitamin D ◽

B12 Deficiency

Although some studies revealed a positive relationship between vitamin D3deficiency and inflammatory markers, there have been also many studies that failed to find this relationship. The aim of this large scaled study is to determine the association between the level of plasma 25 hydroxy vitamin D3[25-(OH) D3] and inflammatory markers in the general population without chronic kidney disease (CKD) and in patients with CKD. Participants with simultaneously measured inflammatory markers and 25-(OH) D3levels were retrospectively analyzed (n=1897). The incidence of all-cause inflammation infection, hospitalization, chronic renal failure, and vitamin B12 deficiency was evaluated. The medians of serum creatinine levels in subjects without renal failure were lower in 25-(OH) D3deficient group. Patients with CKD were more likely to have vitamin D3deficiency compared with normal GFR. 25-(OH) D3levels were associated with a greater incidence of all-cause hospitalization, hypoalbuminemia, and vitamin B12 deficiency. However, there was no relationship between inflammatory markers and vitamin D3levels. In 25-(OH) D3deficient patients, inflammatory markers can be related to other inflammatory and infectious status such as malnutrition and cachexia. We believed that there must be a relationship between vitamin deficiency and inflammatory markers due to other causes than low 25-(OH) D3status.

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Neurobiology of increase in violence in Syria and role of online medical care in its reduction

Journal of Clinical Review & Case Reports ◽

10.33140/jcrc/03/01/00012 ◽

2018 ◽

Vol 3 (1) ◽

Keyword(s):

Vitamin D ◽

Vitamin B12 ◽

Medical Care ◽

Violent Behavior ◽

Vitamin B12 Deficiency ◽

Diabetes Type 2 ◽

Medical Care System ◽

B12 Deficiency ◽

On Line ◽

Care System

Causes of increase in violence in a named society, apart from socio-political and economic reasons, will be examined in this study. One of the most important reasons for increase in levels of hostility in a society is prevalence of psychological depression among population, which can lead to violent behavior and cause physical harm to one self or others, increase in suicidal tendencies and destruction of property. Increase and prevalence of internal medical diseases are one of the main causes of increase in depression, among which diabetes, hypothyroidism, vitamin D, calcium, and vitamin B12 deficiency, dyslipidemia can be mentioned. The main cause for increasing prevalence of depression in Syria can be attributed to: Rapid increase in spread of diabetes. Partially high prevalence of diabetes type 2 (%15.6) Share of other illnesses contributing to depression can be summarized as follows: 47% to spread of vitamin B12 deficiency. In order to have more accurate results further measurements of prevalence of deficiency in vitamin D, calcium, and spread of hypothyroidism, and subclinical hypothyroidism is recommended. By using on line medical care system in Iran, it was found that 85% of people suffering from depression had at least one of the above mentioned causes, and after treatment symptoms of depression were noticeably reduced. At the end of this article there is an announcement for specialists in Syria and other countries to adapt the online medical care system to their own circumstances.

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55: The Risk of Vitamin B12 Deficiency is Low after Ileal Orthotopic Bladder Substitution

The Journal of Urology ◽

10.1016/s0022-5347(18)37317-8 ◽

2004 ◽

Vol 171 (4S) ◽

pp. 15-15

Author(s):

Urs E. Studer ◽

Richard Aebischer ◽

Katharina Ochsner ◽

Werner W. Hochreiter

Keyword(s):

Vitamin B12 ◽

Vitamin B12 Deficiency ◽

B12 Deficiency ◽

Bladder Substitution

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Bioavailability of Vitamin B12

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000041 ◽

2010 ◽

Vol 80 (45) ◽

pp. 330-335 ◽

Cited By ~ 28

Author(s):

Lindsay Helen Allen

Keyword(s):

Vitamin B12 ◽

Vitamin B12 Deficiency ◽

The Elderly ◽

Radioactive Isotopes ◽

Animal Source Foods ◽

Dietary Requirements ◽

In Vivo Labeling ◽

B12 Deficiency ◽

Vitamin B12 Malabsorption

Vitamin B12 deficiency is common in people of all ages who consume a low intake of animal-source foods, including populations in developing countries. It is also prevalent among the elderly, even in wealthier countries, due to their malabsorption of B12 from food. Several methods have been applied to diagnose vitamin B12 malabsorption, including Schillings test, which is now used rarely, but these do not quantify percent bioavailability. Most of the information on B12 bioavailability from foods was collected 40 to 50 years ago, using radioactive isotopes of cobalt to label the corrinoid ring. The data are sparse, and the level of radioactivity required for in vivo labeling of animal tissues can be prohibitive. A newer method under development uses a low dose of radioactivity as 14C-labeled B12, with measurement of the isotope excreted in urine and feces by accelerator mass spectrometry. This test has revealed that the unabsorbed vitamin is degraded in the intestine. The percent bioavailability is inversely proportional to the dose consumed due to saturation of the active absorption process, even within the range of usual intake from foods. This has important implications for the assessment and interpretation of bioavailability values, setting dietary requirements, and interpreting relationships between intake and status of the vitamin.

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Increased monocyte to HDL cholesterol ratio in vitamin B12 deficiency: is it related to cardiometabolic risk?

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000668 ◽

2020 ◽

pp. 1-8

Author(s):

Sanem Kayhan ◽

Nazli Gulsoy Kirnap ◽

Mercan Tastemur

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Uric Acid ◽

Vitamin B12 ◽

Cardiometabolic Risk ◽

Vitamin B12 Deficiency ◽

Left Ventricular ◽

Cardiometabolic Risk Factors ◽

B12 Deficiency ◽

Deficiency Group

Abstract. Vitamin B12 deficiency may have indirect cardiovascular effects in addition to hematological and neuropsychiatric symptoms. It was shown that the monocyte count-to-high density lipoprotein cholesterol (HDL-C) ratio (MHR) is a novel cardiovascular marker. In this study, the aim was to evaluate whether MHR was high in patients with vitamin B12 deficiency and its relationship with cardiometabolic risk factors. The study included 128 patients diagnosed with vitamin B12 deficiency and 93 healthy controls. Patients with vitamin B12 deficiency had significantly higher systolic blood pressure (SBP), diastolic blood pressure (DBP), MHR, C-reactive protein (CRP) and uric acid levels compared with the controls (median 139 vs 115 mmHg, p < 0.001; 80 vs 70 mmHg, p < 0.001; 14.2 vs 9.5, p < 0.001; 10.2 vs 4 mg/dl p < 0.001; 6.68 vs 4.8 mg/dl, p < 0.001 respectively). The prevalence of left ventricular hypertrophy was higher in vitamin B12 deficiency group (43.8%) than the control group (8.6%) (p < 0.001). In vitamin B12 deficiency group, a positive correlation was detected between MHR and SBP, CRP and uric acid (p < 0.001 r:0.34, p < 0.001 r:0.30, p < 0.001 r:0.5, respectively) and a significant negative correlation was detected between MHR and T-CHOL, LDL, HDL and B12 (p < 0.001 r: −0.39, p < 0.001 r: −0.34, p < 0.001 r: −0.57, p < 0.04 r: −0.17, respectively). MHR was high in vitamin B12 deficiency group, and correlated with the cardiometabolic risk factors in this group, which were SBP, CRP, uric acid and HDL. In conclusion, MRH, which can be easily calculated in clinical practice, can be a useful marker to assess cardiovascular risk in patients with vitamin B12 deficiency.

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