Lyme Disease Incidence in Wisconsin: A Comparison of State-reported Rates and Rates from a Population-based Cohort

Objective:The aim of this study was to estimate population based incidence rates for infantile spasms (IS) and to study our clinical impression that the incidence of IS has recently decreased in the Canadian Provinces of Nova Scotia and Prince Edward Island.Methods:Birth cohorts from 1978 to 1998, identified through the hospital health records, EEG records and physician computerized databases, were followed for two years for the development of IS. Disease incidence rates were calculated using denominators derived from Statistics Canada's reported annual live birth rates.Results:The inclusion criteria for IS were fulfilled by 75 patients. The overall incidence of IS was 30.7/100,000 live births (95% CI 24.3, 38.8). Etiologic classification was symptomatic for 51 cases (68%), cryptogenic for 18 (24%), and idiopathic in six children (8%). Although there were more males (N=44) than females (N=31), the incidence rates were similar. There was a marked variability in annual and five-year incidence rates.Conclusion:Although the clinical characteristics of our patients were similar to other reported IS populations, the instability in IS incidence rates indicates a need for caution in interpreting smaller IS epidemiologic studies.

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A population-based exposure assessment of risk factors associated with gastrointestinal pathogens: a Campylobacter study

Epidemiology and Infection ◽

10.1017/s0950268812001641 ◽

2012 ◽

Vol 141 (5) ◽

pp. 976-986 ◽

Cited By ~ 8

Author(s):

L. A. MacRITCHIE ◽

C. J. HUNTER ◽

N. J. C. STRACHAN

Keyword(s):

Risk Factors ◽

Population Density ◽

Exposure Assessment ◽

Disease Incidence ◽

Univariate Analysis ◽

Age Groups ◽

Multivariate Logistic Regression Analysis ◽

Environmental Water ◽

Population Based ◽

Elevated Exposure

SUMMARYA questionnaire survey was undertaken to determine the exposure of a study population to campylobacteriosis source risk factors (environmental, water, food) and results were stratified by age, population density and deprivation. Data were gathered using an exposure assessment carried out by telephone in the Grampian region of Scotland. Univariate analysis showed that children aged 5–14 years, living in low population density (0–44·4 persons/km2) and affluent areas had elevated exposure to environmental and water risk factors. Multivariate logistic regression analysis revealed that younger age groups and lower population density were significant indicators for most environmental risk factors. The results compared to reported disease incidence in Grampian showed that greater exposure to risk factors does not necessarily coincide with greater disease incidence for age groups, particularly for the 0–4 years age group. Further research is required to explain the relationship between exposure and disease incidence.

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Changing Trends in Age and Sex Distributions of Lyme Disease—United States, 1992-2016

Public Health Reports ◽

10.1177/00333549211026777 ◽

2021 ◽

pp. 003335492110267

Author(s):

Kiersten J. Kugeler ◽

Paul S. Mead ◽

Amy M. Schwartz ◽

Alison F. Hinckley

Keyword(s):

United States ◽

Lyme Disease ◽

Disease Incidence ◽

Age Distribution ◽

Relative Size ◽

The United States ◽

Male Predominance ◽

Age Related ◽

Over Time ◽

Age And Sex

Lyme disease is the most common vector-borne disease in the United States and is characterized by a bimodal age distribution and male predominance. We examined trends in reported cases during a 25-year period to describe changes in the populations most affected by Lyme disease in the United States. We examined demographic characteristics of people with confirmed cases of Lyme disease reported to the Centers for Disease Control and Prevention during 1992-2016 through the National Notifiable Diseases Surveillance System. We grouped cases into 5-year periods (1992-1996, 1997-2001, 2002-2006, 2007-2011, 2012-2016). We calculated the average annual incidence by age and sex and used incidence rate ratios (IRRs) to describe changes in Lyme disease incidence by age and sex over time. We converted patient age at time of illness into patient birth year to ascertain disease patterns according to birth cohorts. The incidence of Lyme disease in the United States doubled from 1992-1996 to 2012-2016 (IRR = 1.74; 95% CI, 1.70-1.78) and increased disproportionately among males; IRRs were 39%-89% higher among males than among females for most age groups. During the study period, children aged 5-9 years were most frequently and consistently affected. In contrast, the average age of adults with Lyme disease increased over time; of all adults, people born during 1950-1964 were the most affected by Lyme disease. Our findings suggest that age-related behaviors and susceptibilities may drive infections among children, and the shifting peak among adults likely reflects a probability proportional to the relative size of the baby boom population. These findings can inform targeted and efficient public health education and intervention efforts.

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Analysis of Weather Effects on Variability in Lyme Disease Incidence in the Northeastern United States

Experimental and Applied Acarology ◽

10.1023/a:1025367020459 ◽

2002 ◽

Vol 28 (1-4) ◽

pp. 249-256 ◽

Cited By ~ 2

Author(s):

Susan Subak

Keyword(s):

United States ◽

Lyme Disease ◽

Disease Incidence ◽

Northeastern United States ◽

Weather Effects

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Gender Inequalities in Diagnostic Inertia around the Three Most Prevalent Cardiovascular Risk Studies: Protocol for a Population-Based Cohort Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18084054 ◽

2021 ◽

Vol 18 (8) ◽

pp. 4054

Author(s):

Concepción Carratala-Munuera ◽

Adriana Lopez-Pineda ◽

Domingo Orozco-Beltran ◽

Jose A. Quesada ◽

Jose L. Alfonso-Sanchez ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Disease ◽

Health Care ◽

Cohort Study ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Disease Incidence ◽

Population Based ◽

Gender Inequalities ◽

Primary Health Care Centers

Evidence shows that objectives for detecting and controlling cardiovascular risk factors are not being effectively met, and moreover, outcomes differ between men and women. This study will assess the gender-related differences in diagnostic inertia around the three most prevalent cardiovascular risk factors: dyslipidemia, arterial hypertension, and diabetes mellitus, and to evaluate the consequences on cardiovascular disease incidence. This is an epidemiological and cohort study. Eligible patients will be adults who presented to public primary health care centers in a Spanish region from 2008 to 2011, with hypertension, dyslipidemia, or/and diabetes and without cardiovascular disease. Participants’ electronic health records will be used to collect the study variables in a window of six months from inclusion. Diagnostic inertia of hypertension, dyslipidemia, and/or diabetes is defined as the registry of abnormal diagnostic parameters—but no diagnosis—on the person’s health record. The cohort will be followed from the date of inclusion until the end of 2019. Outcomes will be cardiovascular events, defined as hospital admission due to ischemic cardiopathy, stroke, and death from any cause. The results of this study could inform actions to rectify the structure, organization and training of health care teams in order to correct the inequality.

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Cohort Profile: The China Multi-Ethnic Cohort (CMEC) Study

10.1101/2020.02.14.20022970 ◽

2020 ◽

Author(s):

Xing Zhao ◽

Feng Hong ◽

Jianzhong Yin ◽

Wenge Tang ◽

Gang Zhang ◽

...

Keyword(s):

Clinical Laboratory ◽

Disease Incidence ◽

Data Access ◽

Population Based ◽

Baseline Survey ◽

Individual Level ◽

Long Term Storage ◽

Level Data ◽

The Individual ◽

Study Participants

AbstractCohort purposeThe China Multi-Ethnic Cohort (CMEC) is a community population-based prospective observational study aiming to address the urgent need for understanding NCD prevalence, risk factors and associated conditions in resource-constrained settings for ethnic minorities in China.Cohort BasicsA total of 99 556 participants aged 30 to 79 years (Tibetan populations include those aged 18 to 30 years) from the Tibetan, Yi, Miao, Bai, Bouyei, and Dong ethnic groups in Southwest China were recruited between May 2018 and September 2019.Follow-up and attritionAll surviving study participants will be invited for re-interviews every 3-5 years with concise questionnaires to review risk exposures and disease incidence. Furthermore, the vital status of study participants will be followed up through linkage with established electronic disease registries annually.Design and MeasuresThe CMEC baseline survey collected data with an electronic questionnaire and face-to-face interviews, medical examinations and clinical laboratory tests. Furthermore, we collected biological specimens, including blood, saliva and stool, for long-term storage. In addition to the individual level data, we also collected regional level data for each investigation site.Collaboration and data accessCollaborations are welcome. Please send specific ideas to corresponding author at: [email protected].

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Road proximity, air pollution, noise, green space and neurologic disease incidence: a population-based cohort study

Environmental Health ◽

10.1186/s12940-020-0565-4 ◽

2020 ◽

Vol 19 (1) ◽

Cited By ~ 8

Author(s):

Weiran Yuchi ◽

Hind Sbihi ◽

Hugh Davies ◽

Lillian Tamburic ◽

Michael Brauer

Keyword(s):

Air Pollution ◽

Cohort Study ◽

Green Space ◽

Disease Incidence ◽

Population Based ◽

Neurologic Disease

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Skeletal muscle mass in relation to 10 year cardiovascular disease incidence among middle aged and older adults: the ATTICA study

Journal of Epidemiology & Community Health ◽

10.1136/jech-2019-212268 ◽

2019 ◽

Vol 74 (1) ◽

pp. 26-31 ◽

Cited By ~ 9

Author(s):

Stefanos Tyrovolas ◽

Demosthenes Panagiotakos ◽

Ekavi Georgousopoulou ◽

Christina Chrysohoou ◽

Dimitrios Tousoulis ◽

...

Keyword(s):

Cardiovascular Disease ◽

Skeletal Muscle ◽

Muscle Mass ◽

Skeletal Muscle Mass ◽

Disease Incidence ◽

Population Based ◽

Cardiometabolic Health ◽

Inverse Association ◽

Cvd Risk ◽

Appendicular Skeletal Muscle

BackgroundSkeletal muscle mass (SMM) is inversely associated with cardiometabolic health and the ageing process. The aim of the present work was to evaluate the relation between SMM and 10 year cardiovascular disease (CVD) incidence, among CVD-free adults 45+ years old.MethodsATTICA is a prospective, population-based study that recruited 3042 adults without pre-existing CVD from the Greek general population (Caucasians; age ≥18 years; 1514 men). The 10 year study follow-up (2011–2012) captured the fatal/non-fatal CVD incidence in 2020 participants (50% men). The working sample consisted of 1019 participants, 45+ years old (men: n=534; women: n=485). A skeletal muscle mass index (SMI) was created to reflect SMM, using appendicular skeletal muscle mass (ASM) standardised by body mass index (BMI). ASM and SMI were calculated with specific indirect population formulas.ResultsThe 10 year CVD incidence increased significantly across the baseline SMI tertiles (p<0.001). Baseline SMM showed a significant inverse association with the 10 year CVD incidence (HR 0.06, 95% CI 0.005 to 0.78), even after adjusting for various confounders. Additionally, participants in the highest SMM tertile had 81% (95% CI 0.04 to 0.85) lower risk for a CVD event as compared with those in the lowest SMM tertile.ConclusionsThe presented findings support the importance of SMM evaluation in the prediction of long-term CVD risk among adults 45+ years old without pre-existing CVD. Preservation of SMM may contribute to CVD health.

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