Decontamination Strategies for Filtering Facepiece Respirators (FFRs) in Healthcare Organizations: A Comprehensive Review

Author(s):  
Ashok Kumar Jena ◽  
Jitendra Sharan

Abstract Filtering facepiece respirators (FFRs) are made for one-time use. A massive shortage of FFRs is widespread during pandemic events and has forced many healthcare organizations to decontaminate them and re-use for a limited time. Many decontamination methods have been proposed for the decontamination of FFRs. This review highlights various aspects of decontamination methods available in the literature. Among various methods available, vaporized hydrogen peroxide, ultraviolet irradiation, and dry heat seem to be the most promising decontaminants for FFRs. On the other hand, microwave, bleach, ethylene oxide, alcohol, hydrogen peroxide liquid, sanitizing wipes, and soap and water are not recommended methods for FFR decontamination.

Agronomy ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 599 ◽  
Author(s):  
Nik Nurnaeimah ◽  
Nashriyah Mat ◽  
Khamsah Suryati Mohd ◽  
Noor Afiza Badaluddin ◽  
Nornasuha Yusoff ◽  
...  

Hydrogen peroxide (H2O2) is defined as a reactive oxygen species (ROS), able to cause damage to a variety of cellular structures. On the other hand, recent work has demonstrated that H2O2 can also act as a potent signaling molecule that mediates various physiological and biochemical processes in plants. This study was carried out to investigate the effects of H2O2 on the growth, mineral nutrient accumulation, as well as the biologic and chemical properties of Ficus deltoidea var. deltoidea. F. deltoidea plants were spray-treated with 0- (control), 8-, 16-, 30- and 60-mM H2O2 under field conditions. Plant height, leaf area, chlorophyll content, net photosynthetic rate, stomatal conductance and quantum yield of the F. deltoidea plants significantly increased after treatment with 16 and 30-mM H2O2. The results indicate that 60-mM H2O2 increased the accumulation of arsenic, iron and sodium content in the leaves of F. deltoidea. On the other hand, 8-mM H2O2 significantly enhanced the accumulation of arsenic, iron, calcium and potassium content in the syconium of F. deltoidea plants. In addition, H2O2 treatment did not produce any significant effects on antimony and magnesium accumulation in the leaves or the syconium of F. deltoidea plants. The results show that the F. deltoidea plant has strong antidiabetic properties and its α-glucosidase activity increased in treated plants compared to standard acarbose. Hydrogen peroxide, particularly in concentrations of 16 and 30 mM, increased the antioxidant activity, total phenolic and flavonoid content and the vitexin and isovitexin content. There was a positive correlation between antioxidant activity with total phenol and total flavonoid content in H2O2-treated plants. The quantitative analysis by HPTLC indicates that the amount of vitexin and isovitexin increased with the higher concentrations of H2O2. From this study, it can be concluded that spraying 16 and 30-mM H2O2 once a week enhances growth, mineral accumulation and stimulates bioactive compounds of the F. deltoidea plants.


1924 ◽  
Vol 39 (5) ◽  
pp. 745-755 ◽  
Author(s):  
Oswald T. Avery ◽  
James M. Neill

In the present work on oxidation and reduction by sterile extracts of pneumococcus, the preparations employed contain among other constituents, a hemolytic substance the properties of which have been described by Cole (1, 2) in his studies on pneumococcus hemotoxin. Pneumococcus extracts prepared by the methods described are actively hemolytic, 0.005 cc. of extract causing complete lysis of 2.5 cc. of a 1 per cent suspension of red cells from rabbit blood. This hemolytic property of pneumococcus extracts is destroyed by 10 minutes exposure to 55°C. When pneumotoxin-containing extracts are protected from the action of molecular oxygen, their hemolytic activity remains unimpaired for considerable periods of time. In the presence of air, on the other hand, the stability of the hemolytic substance depends upon whether the particular type of extract contains a "complete" or "incomplete" oxidation-reduction system. Sterile broth extracts of unwashed pneumococci are reactive with molecular oxygen, and as a result of this union peroxide is formed whenever these extracts are exposed to air. The hemolytic activity of "complete" extracts of this type is rapidly decreased and finally destroyed in the presence of molecular oxygen. On the other hand, the "incomplete" type of extract prepared by saline extraction of washed pneumococci may be exposed to air with little or no loss of hemolytic power. This "incomplete" washed cell extract, unless reactivated, does not undergo autoxidation in the presence of air; under these circumstances peroxide is not formed and the hemolytic activity of this type of extract is not impaired by exposure to air. The stability of the hemolytic agent in the "incomplete" type of extract is evidence that this substance is itself not reactive with or affected by molecular oxygen, even in the presence of the cell enzymes. The destruction of the same hemolytic substance in extracts capable of undergoing autoxidation may be ascribed to the action of some peroxide formed by the union of molecular oxygen with easily oxidized or autoxidizable substances of the extract. It is now known that a peroxide, having the reactions of hydrogen peroxide, accumulates in sterile pneumococcus extracts during oxidation. It has been shown in the present study that the addition of preformed hydrogen peroxide destroys the hemolytic activity of pneumococcus extracts, although higher concentrations were required than were detected in oxidized extracts themselves. These facts and the known action of superoxides in analogous types of reaction make it seem not unlikely that the active agent in the destruction of pneumotoxin in oxidized cell extracts may be a peroxide; either hydrogen peroxide or some higher organic peroxide formed during autoxidation of the extract.


2012 ◽  
Vol 717-720 ◽  
pp. 753-756
Author(s):  
Eduardo Pitthan ◽  
Silma A. Corrêa ◽  
Rodrigo Palmieri ◽  
Gabriel Vieira Soares ◽  
Henri I. Boudinov ◽  
...  

The effect of sequential thermal treatments with growth/removal steps of SiO2 films intercalated with hydrogen peroxide treatments on the SiO2/4H-SiC interfacial region thickness were investigated on both Si and C faces. In the Si face case, samples that were submitted to more H2O2 treatments presented thinner interfacial region thicknesses. In the C face case, on the other hand, no significant alteration in this region was observed.


2014 ◽  
Vol 18 (1) ◽  
pp. 37-38 ◽  
Author(s):  
KLARA MARTON

In her keynote paper, Valian (2014) provides a comprehensive review of the literature that examines whether bilingual individuals outperform monolingual participants on various executive processing tasks. The author acknowledges that numerous factors contribute to the outcomes, such as variations in participants’ profile, differences in target functions, as well as variants of tasks and procedures. She also says in her review that, on the one hand, researchers use different tasks to measure similar functions; while, on the other hand, each of these tasks target somewhat different aspects of executive processing. The most widely used tasks, such as the Stroop or flanker tasks, measure several components of executive functions simultaneously.


2015 ◽  
Vol 1 (2) ◽  
pp. 6 ◽  
Author(s):  
Hanan Alhaddi

Triple bottom line (TBL) and sustainability are two related constructs that are used interchangeably in the literature.  A comprehensive review of the relevant literature was conducted and revealed an inconsistent use of the term sustainability.  On the other hand, consistency in terms of referring to the three lines simultaneously is built into the structure of TBL as the construct is explicitly based on the integration of the social, environmental, and economic lines.  The purpose of this paper is not to support an argument that favors the use of one term over the other, but to provide an overview of the presence of both terms in the literature. In light of that, researchers in the business, management, and sustainability fields are encouraged to pay particular attention to how they use these terms in their studies.


First Monday ◽  
2018 ◽  
Author(s):  
Joanna C. Yau ◽  
Stephanie M. Reich ◽  
Yiran Wang ◽  
Melissa Niiya ◽  
Gloria Mark

With social networking sites (SNS) such as Facebook, individuals have immediate access to hundreds of people from different aspects of their lives. On one hand, this may increase the number of people that individuals can interact with directly because communication now requires less effort. On the other hand, individuals may still only interact with a small portion of their networks because humans have limited time and resources. Mayhew and Levinger (1976) proposed that because of time and resource constraints, individuals in larger networks spend, on average, less time with each contact. Thus, while people may have opportunities through Facebook to interact with more people, they may not actually do so. Using logging software, we explored the percentage of their Facebook network that individuals sent direct messages to and whether individuals with larger networks sent direct messages to a smaller percentage of their networks. We found that in line with Mayhew and Levinger’s claim, users messaged a very small percentage of their networks (less than two percent) and that users with larger friend networks sent messages to a smaller percentage of their friend networks. This suggests that while Facebook may enable users to connect with more people than ever before, there are still limits to the number of ties with whom individuals actively interact.


1994 ◽  
Vol 77 (3) ◽  
pp. 631-637 ◽  
Author(s):  
Sophie G Fouler ◽  
Alka B Trivedi ◽  
Naofumi Kitabatake

Abstract The effects of hydrogen peroxide on citrinin and ochratoxin A toxicity were examined using HeLa cells. The citrinin was completely detoxified by prior incubation with 0.05% hydrogen peroxide for 30 min at room temperature, and the toxic compound(s) that resulted from heating citrinin at 100°C were also detoxified upon reheating it with hydrogen peroxide. On the other hand, ochratoxin A was not detoxified by hydrogen peroxide at room temperature, but its toxicity was reduced by heating ochratoxin A with hydrogen peroxide under alkaline conditions.


1925 ◽  
Vol 41 (2) ◽  
pp. 245-255 ◽  
Author(s):  
James B. Murphy ◽  
Ernest Sturm

Rabbits x-rayed in doses sufficient to reduce the amount of their lymphoid tissue without damage to the bone marrow showed a definite deficiency in the production of precipitins, bacterial agglutinins, and protective antibodies. On the other hand, rabbits subjected to exposures of dry heat sufficient to increase the activity of the lymphoid organs, on immunization develop antibodies in larger quantity than do untreated animals immunized by the same process.


2006 ◽  
Vol 11 (1) ◽  
pp. 127
Author(s):  
Carlos Arroyo ◽  
Jorge Mora ◽  
Edgar Vargas ◽  
Javier Gainza

Non traditional alternatives for fungi control were tried on peach palm seed germination process. Two substances - kerosene and gasoline - were found as effective as traditional fungicide treatments triadime- fon and carboxin+benomyl. This is due to their fungicide action and posterior evaporation, not interfering with respiration as is the case with dieses oil. It was found that the hydrogen peroxide accelerates the germination process, but it is not an effective fungicide. On the other hand, kilol seem to be a promising fungicide in this respect if used at a concentration higher than 10 cc/l of water.


1990 ◽  
Vol 259 (6) ◽  
pp. C995-C997 ◽  
Author(s):  
L. Eddy ◽  
A. Arduini ◽  
P. Hochstein

The oxidation of myoglobin was monitored by transmission spectroscopy in isolated, superfused preparations of rat diaphragms. In its deoxygenated form, during anoxia, myoglobin was oxidized by adding hydrogen peroxide (1.0 mM) to its ferryl form (FeIV). On the other hand, peroxide-induced formation of ferrylmyoglobin was not observed when the perfusate contained oxygen. Ferrylmyoglobin was visualized after its derivatization with Na2S to form sulfmyoglobin. Depending on the time of addition, ascorbate (4.0 mM) or ergothioneine (2.0 mM) either prevented the formation of or dissipated ferrylmyoglobin. These agents are known to be reductants of this hypervalent form of myoglobin. In addition to providing the first demonstration of ferrylmyoglobin in skeletal muscle, these observations are consistent with the concept that oxidation of myoglobin to hypervalent states might be an important event in the initiation of muscle damage associated with anoxia and reoxygenation. The rapid reduction of myoglobin would prevent peroxidatic alterations of essential cellular constituents by ferrylmyoglobin.


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