A-043 Preschool Children with Attention Deficit Have Weakness in Reproducing the Rey-Osterrieth Complex Figure in Delayed Recall Condition

Abstract Objectives It was known that children with attention deficit (AD) have also weakness in working memory. In our previous research we have revealed that ADHD children have deficit in visual and verbal memory in delayed recall condition in comparison to immediate condition (Kiselev, 2018). The goal of this research was to examine the hypothesis that preschool children with AD have a deficit in reproducing the Rey-Osterrieth Complex Figure in delayed recall condition. Methods The experimental group included 13 children with AD at the age of 5-6 years. The control group included 13 typically developing children. The children from groups were matched for IQ, gender and age. Children from both groups were assessed with Rey–Osterrieth complex figure test (ROCF). This test is designed to assess reproducing the complex figure in immediate and delayed recall conditions. ANOVA with repeated measures was used to reveal group differences in reproducing the figure in two conditions. Results We have not revealed significant differences between children from experimental and control group in reproducing the figure in immediate condition. However, the interaction of condition type and group was significant (p < .05). Children with AD had weakness in the accurate reproduction and placement of specific design elements of Rey-Osterieth Complex Figure in Delayed Recall condition. Conclusions In view of our previously received results in children with attention deficit, we can propose that deficit in memory in delayed recall condition can be one of the key symptoms in this disorder.

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Women have Farther to Fall: Gender Differences Between Normal Elderly and Alzheimer's Disease in Verbal Memory Engender Better Detection of Alzheimer's Disease in Women

Journal of the International Neuropsychological Society ◽

10.1017/s1355617711000452 ◽

2011 ◽

Vol 17 (4) ◽

pp. 654-662 ◽

Cited By ~ 31

Author(s):

Robert M. Chapman ◽

Mark Mapstone ◽

Margaret N. Gardner ◽

Tiffany C. Sandoval ◽

John W. McCrary ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Gender Differences ◽

Verbal Memory ◽

Control Group ◽

Large Drop ◽

Delayed Recall ◽

Logical Memory ◽

Wechsler Memory Scale ◽

Immediate Recall

AbstractWe analyzed verbal episodic memory learning and recall using the Logical Memory (LM) subtest of the Wechsler Memory Scale-III to determine how gender differences in AD compare to those seen in normal elderly and whether or not these differences impact assessment of AD. We administered the LM to both an AD and a Control group, each comprised of 21 men and 21 women, and found a large drop in performance from normal elders to AD. Of interest was a gender interaction whereby the women's scores dropped 1.6 times more than the men's did. Control women on average outperformed Control men on every aspect of the test, including immediate recall, delayed recall, and learning. Conversely, AD women tended to perform worse than AD men. Additionally, the LM achieved perfect diagnostic accuracy in discriminant analysis of AD versus Control women, a statistically significantly higher result than for men. The results indicate the LM is a more powerful and reliable tool in detecting AD in women than in men. (JINS, 2011, 17, 654–662)

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A-182 Convergent and Divergent Validity of the ChAMP with the CVLT-C and RCFT in Children with Epilepsy

Archives of Clinical Neuropsychology ◽

10.1093/arclin/acaa068.182 ◽

2020 ◽

Vol 35 (6) ◽

pp. 977-977

Author(s):

David C ◽

Brooks B ◽

Macallister W

Keyword(s):

Verbal Memory ◽

Visual Memory ◽

Verbal Learning ◽

California Verbal Learning Test ◽

Divergent Validity ◽

Complex Figure ◽

Visual Tasks ◽

Convergent And Divergent Validity ◽

Learning Test ◽

Figure Test

Abstract Objective As new measures of memory become available, clinicians may be cautious to adopt them without evidence supporting their validity. The present study assesses the convergent and divergent validity of the Child and Adolescent Memory Profile (ChAMP), with the California Verbal Learning Test Children’s (CVLT-C) and the Rey Complex Figure Test (RCFT) in children with epilepsy. Method Twenty four clinically referred children (16 female, 8 male, - age = 12.37 years, SD = 2.68) completed the ChAMP, CVLT-C, and RCFT. Pearson correlations assessed the ChAMP’s convergent and divergent validity with the CVLT-C and the RCFT. Base rate of impairment was calculated for scores ≤2nd percentile. Results The ChAMP verbal tasks demonstrated strong relations with CVLT-C (lists; r = 0.678 p = < .001, instructions; r = 0.724 p = < .001 with CVLT-C learning trials and ChAMP lists free recall with CVLT-C long delay r = 0.580 p = .003). The ChAMP visual tasks correlated strongly with the RCFT delay (objects; r = 0.570 p = .004, places; r = 0.619 p = .001, Visual Memory Index; r = 0.657 p = < .001). However, divergent validity was limited as ChAMP Verbal Memory Index correlated with RCFT delay (r = 0.550 p = .005) and ChAMP Visual Memory Index with CVLT-C delay (r = 0.606 p = .002). Eight percent were deemed impaired on ChAMP lists delay similar to the CVLT-C delay (13%), however, ChAMP places delay identified 21% impaired, compared to the RCFT delay (42%). Conclusions ChAMP scores are strongly correlated with older established measures, but identify fewer cases as clinically impaired. This may reflect the more contemporary normative data or the fact that ChAMP tasks are less multifactorial in nature than are the CVLT-C and RCFT.

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The Brain Metabolic Correlates of the Main Indices of Neuropsychological Assessment in Alzheimer’s Disease

Journal of Personalized Medicine ◽

10.3390/jpm10020025 ◽

2020 ◽

Vol 10 (2) ◽

pp. 25 ◽

Cited By ~ 1

Author(s):

Agostino Chiaravalloti ◽

Maria Ricci ◽

Daniele Di Biagio ◽

Luca Filippi ◽

Alessandro Martorana ◽

...

Keyword(s):

Neuropsychological Assessment ◽

Verbal Learning ◽

Delayed Recall ◽

Auditory Verbal Learning Test ◽

Fdg Uptake ◽

Complex Figure ◽

Auditory Verbal Learning ◽

18F Fdg ◽

Learning Test ◽

Figure Test

Background: The study aimed to investigate the relationships between F-18 fluorodeoxyglucose (18F)FDG uptake and neuropsychological assessment in Alzheimer’s disease (AD). Methods: We evaluated 116 subjects with AD according to the NINCDS-ADRDA criteria. All the subjects underwent a brain PET/CT with (18F)FDG, cerebrospinal fluid (CSF) assay, mini-mental state examination (MMSE) and further neuropsychological tests: Rey auditory verbal learning test, immediate recall (RAVLT immediate); Rey auditory verbal learning test, delayed recall (RAVLT, delayed); Rey complex figure test, copy (RCFT, copy); Rey complex figure test, delayed recall (RCFT, delayed); Raven’s colored progressive matrices (RCPM); phonological word fluency test (PWF) and Stroop test. We performed the statistical analysis by using statistical parametric mapping (SPM12; Wellcome Department of Cognitive Neurology, London, UK). Results: A significant relationship has been reported between (18F)FDG uptake and RAVLT immediate test in Brodmann area (BA)37 and BA22 and with RCFT, copy in BA40, and BA7. We did not find any significant relationships with other tests. Conclusion: In the AD population, brain (18F)FDG uptake is moderately related to the neuropsychological assessment, suggesting a limited impact on statistical data analysis of glucose brain metabolism.

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Using Mobile Electroencephalography and Actigraphy to Diagnose Attention-Deficit/Hyperactivity Disorder: Case-Control Comparison Study (Preprint)

10.2196/preprints.12158 ◽

2018 ◽

Author(s):

Kuo-Chung Chu ◽

Hsin-Ke Lu ◽

Ming-Chun Huang ◽

Shr-Jie Lin ◽

Wen-I Liu ◽

...

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Attention Deficit ◽

Repeated Measures ◽

Performance Test ◽

Memorial Hospital ◽

Diagnostic Tools ◽

Control Group ◽

Chang Gung Memorial Hospital ◽

Hyperactivity Disorder ◽

Significant Difference

BACKGROUND Children with attention-deficit/hyperactivity disorder (ADHD), a neurobehavioral disorder, display behaviors of inattention, hyperactivity, or impulsivity, which can affect their ability to learn and establish proper family and social relationships. Various tools are currently used by child and adolescent psychiatric clinics to diagnose, evaluate, and collect information and data. The tools allow professional physicians to assess if patients need further treatment, following a thorough and careful clinical diagnosis process. OBJECTIVE We aim to determine potential indicators extracted from a mobile electroencephalography (EEG) device (Mindset; NeuroSky) and an actigraph (MotionWatch 8; CamNtech) and to validate them for diagnosis of ADHD. The 3 indicators are (1) attention, measured by the EEG; (2) meditation, measured by the EEG; and (3) activity, measured by the actigraph. METHODS A total of 63 participants were recruited. The case group comprised 40 boys and 9 girls, while the control group comprised 5 boys and 9 girls. The groups were age matched. The test was divided into 3 stages—pretest, in-test, and posttest—with a testing duration of 20 minutes each. We used correlation analysis, repeated measures analysis of variance, and regression analysis to investigate which indicators can be used for ADHD diagnosis. RESULTS With the EEG indicators, the analysis results show a significant correlation of attention with both hit reaction time (RT) interstimulus interval (ISI) change (r=–0.368; P=.003) and hit standard error (SE) ISI change (r=–0.336; P=.007). This indicates that the higher the attention of the participants, the smaller both the hit RT change and the hit SE ISI change. With the actigraph indicator, confidence index (r=0.352; P=.005), omissions (r=0.322; P=.01), hit RT SE (r=0.393; P=.001), and variability (r=0.351; P=.005) were significant. This indicates that the higher the activity amounts, the higher the impulsive behavior of the participants and the more target omissions in the continuous performance test (CPT). The results show that the participants with ADHD present a significant difference in activity amounts (P<0.001). The actigraph outperforms the EEG in screening ADHD. CONCLUSIONS When the participants with ADHD are stimulated under restricted conditions, they will present different amounts of activity than in unrestricted conditions due to participants’ inability to exercise control over their concentration. This finding could be a new electronic physiological biomarker of ADHD. An actigraph can be used to detect the amount of activity exhibited and to help physicians diagnose the disorder in order to develop more objective, rapid auxiliary diagnostic tools. CLINICALTRIAL This research was supported by Chang Gung Memorial Hospital (CMRPG 3F1581 and CORPG 3F0751) and approved by the Institutional Review Board of Chang Gung Memorial Hospital (No. 104-5397B) on October 01, 2015.

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A-065 Weakness in Holistic Processing in Preschool Children is a Risk for SLI

Archives of Clinical Neuropsychology ◽

10.1093/arclin/acaa068.065 ◽

2020 ◽

Vol 35 (6) ◽

pp. 855-855

Author(s):

Kiselev S

Keyword(s):

Risk Factors ◽

Language Impairment ◽

Specific Language Impairment ◽

Holistic Processing ◽

Control Group ◽

Complex Figure ◽

Figure Test ◽

And Gender ◽

And Control ◽

Experimental Group

Abstract Objectives Children with specific language impairment (SLI) have difficulties with producing and understanding language. It is important to search for the risk factors for this deficit in children. The goal of this research was to examine the hypothesis that children at the age of 5 with weakness in holistic processing have a risk for emerging deficit in grammar understanding at the age of 7. Methods 98 children at the age of 5 were assessed with the Rey-Osterieth Complex Figure Test to reveal children with weakness in holistic processing. It was proposed that part-oriented strategy in copying Complex Figure is related to weakness in holistic processing (Luria, 1973). We have revealed 19 children with weakness in holistic processing. These children were included in the experimental group. The control group included 19 children with typical level of holistic processing. Children from experimental and control group were matched for IQ and gender. Children at the age of 7 from both groups were assessed by Grammar Understanding Test from Luria’s neuropsychological assessment technique. Results One-way ANOVA has revealed significant differences [p ≤ 0,05] between groups for scores in Grammar Understanding Test. Children from the experimental group showed a lower level of grammar understanding. Conclusion This research has shown that weakness in holistic processing can predict the delay in development of grammar understanding in children. The received results shed light into underlying nature of SLI. It can be assumed that weakness in holistic processing is one of the risk factors for emerging deficit in grammar understanding in children.

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Effects of a Nine-Month Physical Activity Intervention on Morphological Characteristics and Motor and Cognitive Skills of Preschool Children

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17186609 ◽

2020 ◽

Vol 17 (18) ◽

pp. 6609

Author(s):

Damjan Jaksic ◽

Sandra Mandic ◽

Nebojsa Maksimovic ◽

Zoran Milosevic ◽

Roberto Roklicer ◽

...

Keyword(s):

Physical Activity ◽

Preschool Children ◽

Motor Skills ◽

Repeated Measures ◽

Cognitive Skills ◽

Physical Activity Intervention ◽

Intervention Group ◽

Morphological Characteristics ◽

Assessment System ◽

Control Group

(1) Background: Regular physical activity (PA) plays an important role during early childhood physical and psychological development. This study investigates the effects of a 9-month PA intervention on physiological characteristics and motor and cognitive skills in preschool children. (2) Methods: Preschool children (n = 132; age 4 to 7 years) attending regular preschool programs were nonrandomly assigned to PA intervention (n = 66; 60 min sessions twice per week) or a control group (n = 66; no additional organized PA program) for 9 months. Exercise training for the intervention group included various sports games, outdoor activities, martial arts, yoga, and dance. Anthropometry, motor skills (7 tests), and cognitive skills (Raven’s Colored Progressive Matrices and Cognitive Assessment System) were assessed before and after an intervention period in both groups. Data were analyzed using repeated-measures ANOVA. (3) Results: Body weight significantly increased in both groups over time. Compared to the changes observed in the control group, the intervention group significantly increased in chest circumference (p = 0.022). In contrast, the control group demonstrated an increase in waist circumference (p = 0.001), while these measures in the intervention group remained stable. Participants in the intervention group improved running speed (p = 0.016) and standing broad jump (p = 0.000). The flexibility level was maintained in the intervention group, while a significant decrease was observed in the control group (p = 0.010). Children from the intervention group demonstrated progress in the bent-arm hang test (p = 0.001), unlike the control group subjects. Varied improvements in cognitive skills were observed for different variables in both intervention and control groups, with no robust evidence for PA-intervention-related improvements. (4) Conclusions: Preschool children’s participation in a preschool PA intervention improves their motor skills.

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Regression-Based Norms for the Hopkins Verbal Learning Test-Revised and the Rey–Osterrieth Complex Figure in a Portuguese Adult Population

Archives of Clinical Neuropsychology ◽

10.1093/arclin/acaa087 ◽

2020 ◽

Author(s):

Selene G Vicente ◽

Daniela Ramos-Usuga ◽

Fernando Barbosa ◽

Nuno Gaspar ◽

Artemisa R Dores ◽

...

Keyword(s):

Normative Data ◽

Adult Population ◽

Verbal Learning ◽

Delayed Recall ◽

Immediate Recall ◽

Educational Backgrounds ◽

Complex Figure ◽

Hopkins Verbal Learning Test ◽

Learning Test ◽

Figure Test

Abstract Objective The principal goal of this study was to produce adjusted normative data for European Portuguese native speakers from Portugal on 2 neuropsychological tests widely used to assess learning and memory: the Hopkins Verbal Learning Test-Revised (HVLT-R) and the Rey–Osterrieth Complex Figure Test (ROCF). Method The study included 300 individuals aged 18–92 years (M = 50.4, SD = 21.2), who had educational backgrounds ranging from 3 to 25 years (M = 10.4, SD = 5.2). Results Age, education, and sex were significantly associated with HVLT-R and ROCF performance. These demographic variables accounted for 61% of the variance in HVLT-R total recall, 54% in HVLT-R delayed recall, 18% in HVLT-R recognition, 55% in ROCF copy, and 39% in ROCF immediate recall. Conclusions The normative data are presented as regression-based algorithms to adjust direct and derived test scores for age, education, and sex. This study provides a calculator of normative data derived from the results of the regression models.

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Impaired Recent Verbal Memory in Pornography-Addicted Juvenile Subjects

Neurology Research International ◽

10.1155/2019/2351638 ◽

2019 ◽

Vol 2019 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Pukovisa Prawiroharjo ◽

Hainah Ellydar ◽

Peter Pratama ◽

Rizki Edmi Edison ◽

Sitti Evangeline Imelda Suaidy ◽

...

Keyword(s):

Verbal Memory ◽

Visual Memory ◽

Verbal Learning ◽

Auditory Verbal Learning Test ◽

Complex Figure ◽

Auditory Verbal Learning ◽

Pornography Addiction ◽

Trail Making ◽

Learning Test ◽

Figure Test

We aimed to find the differences in memory capabilities between pornography-addicted and nonaddicted juveniles. We enrolled 30 juveniles (12–16 y) consisting of 15 pornography addiction and 15 nonaddiction subjects. We used Rey Auditory Verbal Learning Test (RAVLT) to measure verbal memory, Rey–Osterrieth Complex Figure Test (ROCFT) for visual memory, along with Trail Making Test A and B (TMT-A and TMT-B) for attention. We found a significant reduction in the RAVLT A6 result of the addiction group (nonaddiction vs addiction: 13.47 ± 2.00 vs 11.67 ± 2.44, MD = −1.80, p=0.04), but not in ROCFT or attention tests. Analysis in sex subgroups yielded no sex-specific difference. We concluded that pornography addiction may be associated with impaired recent verbal memory in juveniles, regardless of sex and without association to attention.

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Cognitive functions in acute unilateral vestibular loss

Journal of Neurology ◽

10.1007/s00415-020-09829-w ◽

2020 ◽

Vol 267 (S1) ◽

pp. 153-159 ◽

Cited By ~ 1

Author(s):

Dilara Aktert Ayar ◽

Emre Kumral ◽

Nese Celebisoy

Keyword(s):

Verbal Memory ◽

Digit Span ◽

Line Orientation ◽

Depression And Anxiety ◽

Vestibular Loss ◽

Canal Paresis ◽

Complex Figure ◽

Visuospatial Functions ◽

Figure Test ◽

Orientation Test

AbstractCognitive deficits mainly involving visuospatial functions have been defined in patients with bilateral and even unilateral vestibular loss (UVL). We compared the cognitive test results of 21 patients with acute UVL with age- and education-matched healthy controls. The diagnosis of UVL was based on the clinical findings, a normal magnetic resonance imaging with diffusion-weighted sequence and canal paresis on the affected side on caloric testing. Cognitive tests assessing visuospatial functions (Benton’s Judgment of Line Orientation test, Verbal and non-verbal Cancellation tests, Rey–Osterrieth Complex Figure test) and global mental status, verbal memory, learning, retention of information, and recalling (Mini Mental State Examination, Oktem Verbal Memory Process Test, Forward and Backward Digit span) were used in addition to Beck depression and Anxiety inventories. Abnormalities in verbal and non-verbal cancellation tests (p < 0.005), Benton’s Judgment of Line Orientation test (p = 0.042) and backward digit span (p = 0.029) was found. A very prominent difference regarding Beck depression (p = 0.012) and anxiety inventories (p < 0.001) was present. On multiple regression analysis, the abovementioned cognitive tests’ results lost their statistical significance (p > 0.05) when depression and anxiety scores were taken into consideration. The severity of canal paresis was found to be correlated with Benton’s Judgment of Line Orientation test (p = 0.008, r = − 0.5639) and Rey–Osterrieth Complex Figure test copying scores (p = 0.029, r = − 0.477). Comparison of all the results in right- and left-sided lesions did not reveal a significant difference (p > 0.05). Vestibular patients are prone to develop anxiety, and depression. Deficits in visuospatial functions, mental manipulation, psychomotor speed and short-term memory detected in our patients with acute UVL seem to be enhanced by accompanying anxiety and depression. The extent of vestibular dysfunction was correlated with the severity of deficits in visuospatial skills. Lesion side did not cause alterations in cognitive or emotional status.

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Memory outcome following transsylvian selective amygdalohippocampectomy in 62 patients with hippocampal sclerosis

Journal of Neurosurgery ◽

10.3171/2008.9.jns08247 ◽

2009 ◽

Vol 110 (6) ◽

pp. 1164-1169 ◽

Cited By ~ 29

Author(s):

Michiharu Morino ◽

Tsutomu Ichinose ◽

Takehiro Uda ◽

Kyoko Kondo ◽

Satoko Ohfuji ◽

...

Keyword(s):

Temporal Lobe ◽

Verbal Memory ◽

Retention Test ◽

Repeated Measures ◽

Hippocampal Sclerosis ◽

Memory Function ◽

Delayed Recall ◽

Nonverbal Memory ◽

Selective Amygdalohippocampectomy ◽

With Memory

Object It remains unclear whether selective amygdalohippocampectomy, an operative technique developed for use in epilepsy surgery to spare unaffected brain tissue and thus minimize the cognitive consequences of temporal lobe surgery, actually leads to a better memory outcome. The present study was performed to determine the effects of selective surgery on memory outcome in patients with intractable mesial temporal lobe epilepsy due to hippocampal sclerosis treated using transsylvian selective amygdalohippocampectomy (TSA). Methods The study population consisted of 62 patients with left hemisphere language dominance who underwent left-(31 patients) or right-sided (31 patients) TSA. All patients underwent comprehensive neuropsychological testing before and 1 month and 1 year after unilateral TSA. Verbal Memory I, Nonverbal Memory I, Total Memory, Attention, and Delayed Recall were assessed using the Wechsler Memory Scale–Revised, whereas Verbal Memory II was assessed using the Miyake Verbal Retention Test (MVRT), and Nonverbal Memory II was assessed using the Benton Visual Retention Test. Separate repeated-measures multivariate analysis of variance (MANOVA) were performed for these intervals with memory scores. Results The results of MANOVA indicated that patients who underwent right-sided TSA showed significant improvements in Verbal Memory I (preoperatively vs 1 month postoperatively, p < 0.0001; and preoperatively vs 1 year postoperatively, p = 0.0002), Nonverbal Memory I (preoperatively vs 1 month postoperatively, p = 0.0003; and preoperatively vs 1 year postoperatively, p = 0.006), and Delayed Recall (preoperatively vs 1 month postoperatively, p = 0.028) at both 1-month and 1-year follow-ups. In addition, Verbal Memory II (MVRT) was also significantly improved 1 year after surgery (p = 0.001). In the group of patients who underwent left-sided TSA, both Verbal Memory I and II were maintained at the same level 1 month after surgery, whereas the Verbal Memory I score 1 year after surgery increased with marginal significance (p = 0.074). In addition, Verbal Memory II showed significant improvement 1 year after surgery (p = 0.049). There were no significant changes in Nonverbal Memory I and II, Attention, or Delayed Recall at either the 1-month or 1-year follow-up. Conclusions Results of the present study indicated that left-sided TSA for hippocampal sclerosis tends to improve verbal memory function with the preservation of other types of memory function. Moreover, right-sided TSA for hippocampal sclerosis can lead to significant improvement in memory function, with memory improvement observed 1 month after right-sided TSA and persisting 1 year after surgery.

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