scholarly journals Neural Correlates of Enhanced Memory for Meaningful Associations with Age

2019 ◽  
Vol 29 (11) ◽  
pp. 4568-4579 ◽  
Author(s):  
Tarek Amer ◽  
Kelly S Giovanello ◽  
Daniel R Nichol ◽  
Lynn Hasher ◽  
Cheryl L Grady
Keyword(s):  
Older Adults ◽  
Age Differences ◽  
Neural Correlates ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Younger Adults ◽  
Age Related ◽  
Cognitive Failure ◽  
Connectivity Patterns ◽  
Control Regions

Abstract Evidence suggests that age differences in associative memory are attenuated for associations that are consistent with prior knowledge. Such knowledge structures have traditionally been associated with the default network (DN), which also shows reduced modulation with age. In the present study, we investigated whether DN activity and connectivity patterns could account for this age-related effect. Younger and older adults underwent functional magnetic resonance imaging as they learned realistic and unrealistic prices of common grocery items. Both groups showed greater activity in the DN during the encoding of realistic, relative to unrealistic, prices. Moreover, DN activity at encoding and retrieval and its connectivity with an attention control network at encoding were associated with enhanced memory for realistic prices. Finally, older adults showed overactivation of control regions during retrieval of realistic prices relative to younger adults. Our findings suggest that DN activity and connectivity patterns (traditionally viewed as indicators of cognitive failure with age), and additional recruitment of control regions, might underlie older adults’ enhanced memory for meaningful associations.

scholarly journals From Synchrony to Asynchrony: Cerebellar-Basal Ganglia Functional Circuits in Young and Older Adults

2018 ◽  
Author(s):  
Hanna K. Hausman ◽  
T. Bryan Jackson ◽  
James R.M. Goen ◽  
Jessica A. Bernard
Keyword(s):  
Magnetic Resonance Imaging ◽  
Older Adults ◽  
Basal Ganglia ◽  
Age Differences ◽  
Resting State ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Reciprocal Connections ◽  
Connectivity Patterns ◽  
Fmri Analysis

AbstractResting state functional magnetic resonance imaging (rs-fMRI) has indicated disruptions in functional connectivity in older (OA) relative to young adults (YA). While age differences in cortical networks are well studied, differences in subcortical networks are poorly understood. Both the cerebellum and the basal ganglia are of particular interest given their role in cognitive and motor functions, and work in non-human primates has demonstrated direct reciprocal connections between these regions. Here, our goal was twofold. First, we were interested in delineating connectivity patterns between distinct regions of the cerebellum and basal ganglia, known to have topologically distinct connectivity patterns with cortex. Our second goal was to quantify age-differences in these cerebellar-striatal circuits. We performed a targeted rs-fMRI analysis of the cerebellum and basal ganglia in 33 YA and 31 OA individuals. In the YA, we found significant connectivity both within and between the cerebellum and basal ganglia, in patterns supporting semi-discrete circuits that may differentially subserve motor and cognitive performance. We found a shift in connectivity, from one of synchrony in YA, to asynchrony in OA, resulting in substantial age differences. Connectivity was also associated with behavior. These findings significantly advance our understanding of cerebellar-basal ganglia interactions in the human brain.

Age Differences in the Social Associative Learning of Trust Information

2022 ◽  
Author(s):  
Kendra Leigh Seaman ◽  
Alexander P. Christensen ◽  
Katherine Senn ◽  
Jessica Cooper ◽  
Brittany Shane Cassidy
Keyword(s):  
Older Adults ◽  
Age Differences ◽  
Social Cues ◽  
Trust Game ◽  
Time Model ◽  
Younger Adults ◽  
Cortical Areas ◽  
Age Related ◽  
The Social ◽  
Over Time

Trust is a key component of social interaction. Older adults, however, often exhibit excessive trust relative to younger adults. One explanation is that older adults may learn to trust differently than younger adults. Here, we examine how younger (N=33) and older adults (N=30) learn to trust over time. Participants completed a classic iterative trust game with three partners. Younger and older adults shared similar amounts but differed in how they shared money. Compared to younger adults, older adults invested more with untrustworthy partners and less with trustworthy partners. As a group, older adults displayed less learning than younger adults. However, computational modeling shows that this is because older adults are more likely to forget what they have learned over time. Model-based fMRI analyses revealed several age-related differences in neural processing. Younger adults showed prediction error signals in social processing areas while older adults showed over-recruitment of several cortical areas. Collectively, these findings suggest that older adults attend to and learn from social cues differently from younger adults.

scholarly journals Adult age differences in subjective responses to dynamic socioemotional incentives

2020 ◽  
Author(s):  
Sade J Abiodun ◽  
Galen McAllister ◽  
Gregory Russell Samanez-Larkin ◽  
Kendra Leigh Seaman
Keyword(s):  
Older Adults ◽  
Age Differences ◽  
Emotional Valence ◽  
Incentive Motivation ◽  
Social Signals ◽  
Younger Adults ◽  
Positivity Effect ◽  
Adult Age ◽  
Age Related ◽  
Adult Age Differences

Facial expressions are powerful communicative social signals that motivate feelings and action in the observer. However, research on incentive motivation has overwhelmingly focused on money and points and the limited research on social incentives has been mostly focused on responses in young adulthood. Previous research on the age-related positivity effect and adult age differences in social motivation suggest that older adults might experience higher levels of positive arousal to socioemotional stimuli than younger adults. Affect ratings following dynamic emotional expressions (anger, happiness, sadness) varying in magnitude of expression showed that higher magnitude expressions elicited higher arousal and valence ratings. Older adults did not differ significantly in levels of arousal when compared to younger adults, however their ratings of emotional valence were significantly higher as the magnitude of expressions increased. The findings provide novel evidence that socioemotional incentives may be relatively more reinforcing as adults age. More generally, these dynamic socioemotional stimuli that vary in magnitude are ideal for future studies of more naturalistic affect elicitation, studies of social incentive processing, and use in incentive-driven choice tasks.

scholarly journals ANGER, LOVE, SADNESS: DO EMOTION WORDS HAVE THE SAME SEMANTIC MEANING ACROSS AGE-GROUPS?

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S841-S842
Author(s):  
Madeline J Nichols ◽  
Jennifer A Bellingtier ◽  
Frances Buttelmann
Keyword(s):  
Older Adults ◽  
Age Differences ◽  
Language Use ◽  
Age Groups ◽  
Past Research ◽  
Semantic Meaning ◽  
Younger Adults ◽  
Emotion Words ◽  
Emotion Word ◽  
Age Related

Abstract Every day we use emotion words to describe our experiences, but past research finds that the meanings of these words can vary. Furthermore, historical shifts in language use and experiential knowledge of the emotions may contribute to age-differences in what these emotion words convey. We examined age-related differences in the valence, arousal, and expression connoted by the words anger, love, and sadness. We predicted age-related differences in the semantic meanings of the words would emerge such that older adults would more clearly differentiate the positivity/negativity of the words, whereas younger adults would report higher endorsement for the conveyed arousal and expression. Participants included American and German older adults (N=61; mean age=68.98) and younger adults (N=77; mean age=20.77). Using the GRID instrument (Swiss Center for Affective Sciences, 2013), they rated each emotion word for its valence, arousal, and expression when used by a speaker of the participant’s native language. Across emotions and dimensions, older adults were generally more moderate in their understanding of emotion words. For example, German older adults rated anger and sadness as suggesting the speaker felt less bad and more good than the younger adults. American older adults rated love as connoting the speaker felt more bad and less good than younger adults. Arousal ratings were higher for German younger, as opposed to older, adults. Cultural differences were most pronounced for sadness such that German participants gave more moderate answers than American participants. Overall, our research suggests that there are age-related differences in the understanding of emotion words.

scholarly journals Deviations From Bayes' Theorem During Belief Updating In Younger And Older Adults: Evidence From Behaviour And Neural Activity

2021 ◽  
Author(s):  
Bonnie Andrea Armstrong
Keyword(s):  
Older Adults ◽  
Cognitive Control ◽  
Age Differences ◽  
Prior Information ◽  
Bayes Theorem ◽  
Neural Correlates ◽  
Belief Updating ◽  
Younger Adults ◽  
Ambiguous Information ◽  
New Information

Updating prior information with new information in accordance with Bayesian principles is a difficult task. Younger adult decision makers deviate from Bayes’ theorem by either overweighting prior information (i.e., using a conservatism heuristic) or overweighting new information (i.e., using a representativeness heuristic) on decision tasks without feedback. Similar to younger adults, older adults make decisions that require belief updating. Given agerelated decrements in cognitive control, older adults may be at a disadvantage compared with younger adults when updating beliefs. Prior research shows no age differences when making decisions under risk, however older adults perform worse than younger adults when making decisions under ambiguity. Currently it is unknown how older adults use heuristics when updating beliefs about risk and ambiguous information compared with younger adults. The primary aim of this dissertation was to examine age-related differences in the use of heuristics during belief updating, as well as the cognitive processes and neural correlates that underpin behaviour. In three experiments, younger and older adults completed a belief updating task with and without feedback using an urn-ball paradigm. The main results showed that both younger and older adults committed the representativeness error more than the conservatism error, with no age differences observed when updating beliefs without feedback but with younger adults updating beliefs more accurately than older adults with feedback. Further, age differences in the neural correlates that underlie belief updating showed evidence that older adults recruit additional resources in frontal regions of the brain to facilitate performance compared with younger adults. Event-related potentials showed evidence of cognitive control in response to conflicting information in both age groups, but a diminished neural response to feedback in older compared with younger adults. Additionally, while younger adults were not influenced by ambiguous information, older adults avoided committing the representativeness error only when new information was ambiguous. Last, individual differences in numeracy and cognitive reflection, but not thinking disposition, modulated belief updating performance. Together, the results show that younger and older adults can learn to update beliefs with feedback but with younger adults learning to a greater degree than older adults, especially when information is ambiguous.

scholarly journals Encoding and retrieval eye movements mediate age differences in pattern completion

2020 ◽  
Author(s):  
Jordana Wynn ◽  
Bradley Buchsbaum ◽  
Jennifer Ryan
Keyword(s):  
Older Adults ◽  
Age Differences ◽  
False Alarms ◽  
Memory Errors ◽  
Younger Adults ◽  
Pattern Completion ◽  
Age Related ◽  
Retrieval Processes ◽  
New Information ◽  
Encoding And Retrieval

Older adults often mistake new information as ‘old’, yet, the mechanisms underlying this response bias remain unclear. Typically, false alarms by older adults are thought to reflect pattern completion – the retrieval of a previously encoded stimulus in response to partial input. However, other work suggests that age-related retrieval errors can be accounted for by deficient encoding processes. In the present study, we used eye movement (EM) monitoring to quantify older adults’ pattern completion bias as a function of EMs during both encoding and partially cued retrieval. Analysis of EMs revealed reduced encoding-related differentiation (i.e., more similar EMs across encoded images) and increased retrieval-related reinstatement (i.e., more similar EMs across encoding and retrieval) by older relative to younger adults, with both encoding and retrieval EMs predicting false alarms. These findings indicate that age-related changes in both encoding and retrieval processes, indexed by EMs, underlie older adults’ increased vulnerability to memory errors.

scholarly journals Pronoun production remains stable over the adult lifespan for contexts with topic continuity

2022 ◽  
Author(s):  
Madeleine Long ◽  
Hannah Rohde ◽  
Paula Rubio-Fernandez
Keyword(s):  
Older Adults ◽  
Age Differences ◽  
Perspective Taking ◽  
Referential Communication ◽  
Main Character ◽  
Younger Adults ◽  
Discourse Context ◽  
Adult Lifespan ◽  
Age Related ◽  
Referential Choice

A prevalent finding in the referential communication literature is that older adults produce more ambiguous pronouns than younger adults, likely because they have difficulty determining the prominence of referents. This finding has been widely understood to reflect a general age-related deficit in communication. However, all studies from this line of work have used materials involving topic shifts (i.e. when the to-be-named referent shifts from one character to another, which requires perspective-taking and can be cognitively costly). To determine the extent to which younger and older adults’ pronominal use diverges, we investigated whether other aspects of the discourse context influence age-related differences in referential choice, apart from topic shifts. Here we tested a large sample of adults (N=496, ages 18-82) using narrative elicitation tasks across four experiments and nine contexts of topic continuity (i.e. contexts in which the to-be-named referent remained the same). In Experiments 1 and 2, we varied the number of characters in the scene while keeping the sex/gender of the characters distinct and found that pronominal use did not differ by age for scenes with 1, 2, and 3 characters. In Experiments 3 and 4, we varied the number of characters, the sex/gender of those characters (such that they were the same or different), and the linguistic emphasis placed on the main character. Again, we found no age differences across all conditions. Taken together, our findings suggest that older adults’ difficulty with prominence estimates is not all- encompassing, but rather appears to be confined to contexts involving topic shifts.

scholarly journals Virtual Hand Illusion in younger and older adults

2021 ◽  
Vol 8 ◽  
pp. 205566832110593
Author(s):  
Jennifer L. Campos ◽  
Graziella El-Khechen Richandi ◽  
Marge Coahran ◽  
Lindsey E. Fraser ◽  
Babak Taati ◽  
...  
Keyword(s):  
Older Adults ◽  
Virtual Environments ◽  
Age Differences ◽  
Age Groups ◽  
Tactile Feedback ◽  
Younger Adults ◽  
Localization Accuracy ◽  
Virtual Hand ◽  
Age Related ◽  
Spatio Temporal

Introduction Embodiment involves experiencing ownership over our body and localizing it in space and is informed by multiple senses (visual, proprioceptive and tactile). Evidence suggests that embodiment and multisensory integration may change with older age. The Virtual Hand Illusion (VHI) has been used to investigate multisensory contributions to embodiment, but has never been evaluated in older adults. Spatio-temporal factors unique to virtual environments may differentially affect the embodied perceptions of older and younger adults. Methods Twenty-one younger (18–35 years) and 19 older (65+ years) adults completed the VHI paradigm. Body localization was measured at baseline and again, with subjective ownership ratings, following synchronous and asynchronous visual-tactile interactions. Results Higher ownership ratings were observed in the synchronous relative to the asynchronous condition, but no effects on localization/drift were found. No age differences were observed. Localization accuracy was biased in both age groups when the virtual hand was aligned with the real hand, indicating a visual mislocalization of the virtual hand. Conclusions No age-related differences in the VHI were observed. Mislocalization of the hand in VR occurred for both groups, even when congruent and aligned; however, tactile feedback reduced localization biases. Our results expand the current understanding of age-related changes in multisensory embodiment within virtual environments.

scholarly journals Age differences in cognitive control of emotional memory: metacognitive aspects and neural correlates

2021 ◽  
Author(s):  
Sara Nicole Gallant
Keyword(s):  
Older Adults ◽  
Cognitive Control ◽  
Age Differences ◽  
Later Life ◽  
Well Being ◽  
Neural Correlates ◽  
Emotional Memory ◽  
Directed Forgetting ◽  
Age Related ◽  
Related Potentials

Previous research has identified a divergent trajectory for the aging brain, characterized by declines in cognition and preservation in emotional processing. According to the socioemotional selectivity theory, reduced time horizons in later life cause a motivational shift to prioritize emotional goals, such as positive well-being. In service of these goals, older adults devote more cognitive effort to attend to and remember positive information; however, whether they can exert control over such information once it enters memory is not well understood. The primary aim of this dissertation was thus to examine age-related changes in cognitive control of emotional memory including its underlying metacognitive and neural components. In three experiments, young and older adults completed a cue- or value-based version of the item-directed forgetting task for positive, negative, and neutral words. Results consistently demonstrated that young and older adults could strategically control encoding of emotional information, by prioritizing relevant over irrelevant words in memory. This was evident when encoding was directed by to-be-remembered (TBR) or to-be-forgotten (TBF) cues as well as by numeric points that signaled a gain or loss of value (+10 vs. -10). Extending previous research on metacognition and aging, results indicated age invariance in prospective judgments of learning made during the encoding of TBR and TBF words that varied in emotion. In contrast, age groups differed when retrospectively monitoring the source of words. Whereas young adults’ source monitoring was not influenced by emotion or cues, older adults tended to attribute positive items to sources that were higher in value for memory (TBR or +10 cues), consistent with an age-related bias to prioritize positivity. Finally, age differences in event-related potentials underlying encoding of TBR and TBF words provided evidence that older adults may recruit additional resources in frontal regions of the brain to facilitate task performance. Moreover, in line with behavioural results, the ERP signatures of directed forgetting were not modulated by emotion. Altogether, this dissertation demonstrates that cognitive control over emotional memory is intact in later life; however, it highlights important age differences in the metacognitive and neural correlates of this ability.

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