DOZ047.87: Longitudinal evaluation of lung function in infants with esophageal atresia

2019 ◽  
Vol 32 (Supplement_1) ◽  
Author(s):  
F Landolfo ◽  
A Conforti ◽  
C Columbo ◽  
F Calzolari ◽  
F Savignoni ◽  
...  
Keyword(s):  
Lung Function ◽  
Esophageal Atresia ◽  
Lung Function Test ◽  
Time To Peak ◽  
Significant Difference ◽  
Function Test ◽  
Retrospective Nature ◽  
Short And Long Term ◽  
The Impact

Abstract Introduction Patients affected by esophageal atresia (EA) often faced airway problems, due to multifactorial dynamics (tracheomalacia, gastroesophageal reflex disorder, etc.). The aim of this study was to longitudinally evaluate the lung function test (LFT) in those infants to explore how the LFT modifies at mid-term follow-up. Methods Retrospective evaluation of lung functions in infants treated for EA (2010–2017) was performed at three time points: 6 months, 12 months, and 24 months. Tidal volume (Vt), respiratory rate (RR), and time to peak tidal expiratory flow as a percentage of total expiratory time (tPTEF/te) were analyzed. ANOVA test was used as appropriate. Results During the study period 172 patients were treated for EA. Of those 50 infants (28%) underwent LFT at 6 months, 30 at 12 months, and 11 at 24 months. Tracheomalacia was present in 20 infants (42%). Both Vt (6,79 ml/kg vs 7,82 ml/kg vs 8,37 ml/kg—p = 0,001) and RR (49,7 a/min vs 40,6 a/min vs 34,0 a/min—p = 0,020) significantly improved, while there was no significant difference for tPTEF/te (0,25 vs 0,26 vs 0,29—p = 0,62) despite the data showing an improvement trend. Conclusion The preliminary data suggest that, although EA patients may present impaired LTF in early infancy, lung function seems to improve over time, showing normal pulmonary function test at 24 months. The presence of selection bias and the retrospective nature of the study limit our result. Nonetheless, evaluation of lung function is warranted in EA infants to early detect respiratory symptoms, ideally reducing the impact on short- and long-term pulmonary outcomes.

Market reaction to open innovation announcements

2018 ◽  
Vol 21 (1) ◽  
pp. 142-156 ◽  
Author(s):  
Dawid Szutowski
Keyword(s):  
Open Innovation ◽  
Information Disclosure ◽  
The European Union ◽  
Content Type ◽  
Service Companies ◽  
Significant Difference ◽  
Short And Long Term ◽  
The Impact ◽  
Positive Effect

Purpose Open innovation is of crucial importance for all companies operating in the economics of widely distributed knowledge. However, the effects of its disclosure remain largely uncharted in the case of service companies. Therefore, the purpose of this paper is to measure the impact of open innovation announcements on the market value (MV) of service enterprises. Design/methodology/approach The research covered 398 open innovation announcements released by service companies. It was conducted in the whole of the European Union in the period February 2011-December 2016. The data were analysed in the short and long term with the use of event-study and buy-and-hold methods. Findings The results indicated the significant positive effect of open innovation disclosure in both short and long term. At the same time, the market was not able to immediately fully value the information in the short run and tended to overestimate the positive effect of the innovation announced. No significant leakage and dissemination effects were observed prior to the announcement. There was no significant difference in the magnitude of positive and negative reactions to the releases. Practical implications From the point of view of business practice the research proved the benefits of information disclosure and supported the long-term planning. From the investors’ viewpoint, it signalled the small risk of significant fluctuations resulting from aggressive trading prior to the announcement and unwinding part of the acquired position afterwards. Originality/value The paper attempts to fulfil the research gap on the impact of the announcements on open innovation on the MV of companies.

scholarly journals Effect of wearing cotton towel Ihram and plain Ihram on lung function among Hajj Pilgrims

2019 ◽  
Vol 35 (4) ◽  
Author(s):  
Sultan Ayoub Meo ◽  
Muhammad Iqbal ◽  
Adnan Mahmood Usmani ◽  
Abdulrahman Abdulaziz Almana ◽  
Abdulrahman Hamad Alrashed ◽  
...  
Keyword(s):  
Lung Function ◽  
Lung Function Test ◽  
Large Sample Size ◽  
Base Line ◽  
Creative Commons ◽  
Test Parameters ◽  
Significant Difference ◽  
Function Test ◽  
Forced Expiratory Flow ◽  
Expiratory Flow

Objectives: Hajj is the world’s largest gathering to Makkah, Saudi Arabia. Wearing cotton made Ihram is a basic and an essential component of Hajj. The aim of this study was to investigate the lung functions among Hajj pilgrims who were wearing cotton towel ihram (ihram with fibers) compared to those who were wearing plain cotton ihram (ihram without fibers). Methods: Ninety male, non-smoker, Hajj pilgrim volunteers with age ranged 20-60 years were selected. Forty five of them wore cotton towel ihram and 45 wore plain ihram. A day before leaving for Hajj and wearing ihram (6th Dhu-al-Hijjah) lung function base line parameters of Hajj pilgrims were determined. Hajj Pilgrims continuously wear ihram from 7-10th Dhu-al-Hijjah. In the afternoon of 10th Dhu-al-Hijjah, after removal of ihram, all parameters were repeated and at the completion of Hajj when all pilgrims return to their homes at Riyadh, all parameters were recorded again. Results: Before wearing Ihram, anthropometric and lung function baseline parameters were recorded, no significant difference was found between the study population. After wearing Ihram on the 7th Dhu-al-Hijjah and its removal on the 10th Dhu-al-Hijjah significant decline in the lung function test parameters was observed among Hajj pilgrims who were wearing cotton towel ihram. Forced Vital Capacity (FVC) 4.30±1.18 vs. 5.03±1.41 (p=0.01); Forced Expiratory Flow 25% (FEF-25%) 4.39±1.94 vs. 5.69±2.84 (p=0.03); Forced Expiratory Flow-50% (FEF-50%) 2.93±1.65 vs. 4.07±2.08 (p=0.01); Forced Expiratory Flow-75% (FEF-75%) 1.02±0.70 vs. 1.66±0.94 (p=0.002) compared to those who were wearing plain ihram. Conclusions: Lung function test parameters were decreased among the Hajj pilgrims who were wearing cotton towel ihram compared to those who were wearing plain cotton ihram. The pattern of impairment of lung function shows an obstructive peripheral airway lung involvement. It is suggested to conduct further large sample size studies to confirm the present study observations and reach at better conclusions. doi: https://doi.org/10.12669/pjms.35.4.727 How to cite this:Meo SA, Iqbal M, Usmani AM, Almana AA, Alrashed AH, Al-Regaiey KA. Effect of wearing cotton towel Ihram and plain Ihram on lung function among Hajj Pilgrims. Pak J Med Sci. 2019;35(4):---------. doi: https://doi.org/10.12669/pjms.35.4.727 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Effect of Box Breathing Technique on Lung Function Test

2021 ◽  
pp. 25-31
Author(s):  
Ashfaaq Ahmed ◽  
R. Gayatri Devi ◽  
A. Jothi Priya
Keyword(s):  
Lung Function ◽  
Vital Capacity ◽  
Lung Function Test ◽  
Inhibitory Response ◽  
Forced Expiratory Volume ◽  
P Value ◽  
Significant Difference ◽  
Function Test ◽  
Slow Breathing ◽  
Experimental Training

Background: Box breathing exercise is a technique of slow breathing rhythm also known as square breathing used universally. It increases the performance and concentration level, it also acts as a powerful stress relief. It is tested with a spirometer for the lung function test that measures the airflow of the upper and lower respiratory tract. This method builds up carbon dioxide in blood which calms down and regulates the ANS (Autonomic Nervous System), which enhances the cardio- inhibitory response of the vagus nerve that improves the mood. The main aim of the study was to analyze the effect of box breathing technique on lung function Materials and Methods: The present study was carried out among the participants at the age of 18-25 years from Saveetha Dental College. A total of 30 participants were included in this study (15 males, 15 females). The experimental training procedures consisted of 2 sessions of box breathing day and night for a period of 30 days. Participants were informed of the procedures of the box breathing technique. RMS Helios spirometer was used to measure lung volumes and capacities. Statistics analysis was done using SPSS software, paired t test. P value of less than or equal to 0.05 was considered significant statistically. Results: There was a significant increase among the participants FVC (Forced Vital Capacity), FEV1 (Forced Expiratory Volume), FIVC (Forced Inspiratory Vital Capacity) parameters after 2 sessions on each day of box breathing technique for a period of 30 days. Other parameters increased to 10% but not significantly. Conclusion: The present study illustrates the potential for box breathing practice to improve lung performance and reduce stress in healthy individuals. Despite the significant difference in FVC, FEV, FIVC levels supporting improved lung function, further investigation is needed to delineate mechanisms that underlie these benefits

scholarly journals Peak Expiratory Flow Rate Among Rural and Urban Normal School Children in Chattogram, Bangladesh

2019 ◽  
Vol 18 (1) ◽  
pp. 18-22
Author(s):  
AKM Zafarullah ◽  
Md Badrul Alam ◽  
Moinuddin Ahmed ◽  
Ashutosh Das ◽  
Md Shah Alam
Keyword(s):  
Lung Function ◽  
Peak Expiratory Flow ◽  
Flow Rate ◽  
School Children ◽  
Peak Expiratory Flow Rate ◽  
Lung Function Test ◽  
Rural And Urban ◽  
Significant Difference ◽  
Function Test ◽  
Expiratory Flow

Background: Asthma remain the most common chronic inflammatory lung disease in childhood. Asthma management needs lung function assessment. Peak Expiratory Flow Rate (PEFR) is one of the lung function test. PEFR has been used as measure of ventilatory capacity for long mainly because of a simple, less tiring procedure than other lung function test. It is easy to use, inexpensive, portable, reliable can be used by patients, parents, home & clinic. There is no national nomogram on PEFR in Bangladesh. We always use the nomogram of other countries for diagnosis, management of Asthma. This study was taken to establish what is the normal pattern of PEFR in Bangladeshi children of rural and urban area and to construct nomogram of PEFR in healthy Bangladeshi children. Materials and methods : It is a cross sectional study conducted in different 6 schools (Urban & rural) in Chattogram District of both sexes (5-15 yrs old) in equal proportion of child. Study period was from April 2009 to November 2009 under supervision of Pediatrics Department of Chattogram Medical College. Sample was selected by non-probability technique. Data were collected by pretested questionnaire including exclusion criteria. Results: A total of 1424 healthy school children (Age 5-15 yrs) of equal sexes of both rural and urban school were included during study. The best of three PEFR of boys ranged from 90 to 750 I/min (Mean 291 I/min, SD 143) and in case of girls ranged from 80 to 540 (L/min (mean 236 L/min, SD 94.38). The positive correlation of PEFR with various anthrometric parameters specially height and observed difference with boys and girls. The most significant correlation was observed PEFR with height and also found different value of PEFR between rural and urban children. Conclusion : This study concluded that there is significant difference of PEFR between Bangladeshi boys and girls (5-15 yrs). Height is the best predictor of PEFR value than any other anthrometric parameters PEFR value of Bangladeshi Girls is lower than that of Boys and significant difference between PEFR values among urban & rural Bangladeshi children. Chatt Maa Shi Hosp Med Coll J; Vol.18 (1); Jan 2019; Page 18-22

scholarly journals Estimation of Lung Function Test among Healthy and Blow out Whistle Beginners

2021 ◽  
pp. 459-464
Author(s):  
Padmalochini Sudharsan ◽  
R. Gayatri Devi ◽  
A. Jothi Priya
Keyword(s):  
Lung Function ◽  
Lung Function Test ◽  
Study Data ◽  
Dental Students ◽  
Respiratory Disorder ◽  
Healthy Individuals ◽  
Breathing Exercises ◽  
Significant Difference ◽  
Function Test ◽  
Post Test

Introduction: Pulmonary function test is a non-invasive test. It is measured by the spirometer and it gives an idea about the lung volume, lung capacities, rates of flow and gas exchange. Breathing exercise can increase lung function. The commonly performed breathing exercises are blowing bubbles, blow out whistle, pinwheels, Hoberman spheres etc. The aim of this study is to estimate lung function among healthy and blow out whistle beginners. Materials and methods: 60 Dental students consisting of 2 groups were involved in this study. Group 1: Control individuals (30). Group 2 individuals: blow out whistle beginners (30). Standardised RMS Helios spirometer was used. Age of 18-22, Healthy individuals and non-smokers were included in this study and smokers, alcoholic individuals, respiratory disorder individuals and post- COVID individuals were excluded from the study. Data was collected and analysed using paired ‘t’ tests. Significance is considered at P<0.05 level. Results: In this study FVC, FEV1, FEV3 were found to be significant and FEV1/FVC, FEF 25-75, PEFR were found to be insignificant. The post test values of FVC and FEV1 are comparatively higher than the pre test values. The pre test values of FEF 25-75 and  FEV3 are comparatively higher than the post test values. Conclusion: When this blow out exercise is performed there was a significant difference between healthy individuals and blow out whistle beginners. Significant increase in lung function is found. This recreational activity increases lung function which can be a preventive for many pulmonary diseases.

The influence of inflation targeting on the pass-through effect of the exchange rate

2018 ◽  
pp. 70-84
Author(s):  
Ph. S. Kartaev ◽  
Yu. I. Yakimova
Keyword(s):  
Developing Countries ◽  
Monetary Policy ◽  
Exchange Rate ◽  
Inflation Targeting ◽  
Policy Regime ◽  
Short And Long Term ◽  
The Exchange Rate ◽  
Pass Through ◽  
The Impact

The paper studies the impact of the transition to the inflation targeting regime on the magnitude of the pass-through effect of the exchange rate to prices. We analyze cross-country panel data on developed and developing countries. It is shown that the transition to this regime of monetary policy contributes to a significant reduction in both the short- and long-term pass-through effects. This decline is stronger in developing countries. We identify the main channels that ensure the influence of the monetary policy regime on the pass-through effect, and examine their performance. In addition, we analyze the data of time series for Russia. It was concluded that even there the transition to inflation targeting led to a decrease in the dependence of the level of inflation on fluctuations in the ruble exchange rate.

Lung Function Test for Workers and its Quality Control Program

1994 ◽  
Vol 6 (2) ◽  
pp. 187
Author(s):  
Jung Keun Choi ◽  
Mi A Son ◽  
Hyun Kyung Kim ◽  
Domyung Paek ◽  
Byung Soon Choi
Keyword(s):  
Quality Control ◽  
Lung Function ◽  
Control Program ◽  
Lung Function Test ◽  
Quality Control Program ◽  
Function Test

SHORT AND LONG-TERM RECOVERY IN BURNED WATERSHEDS AND THE IMPACT ON STREAMFLOW DYNAMICS

2016 ◽  
Author(s):  
Terri S. Hogue ◽  
◽  
Samuel Saxe ◽  
Ryan Logan ◽  
Kyle Knipper ◽  
...  
Keyword(s):  
Short And Long Term ◽  
The Impact

Impact of Hybrid Operating Rooms on Long-Term Clinical Outcomes Following Fenestrated and Branched Endovascular Aortic Repair

2021 ◽  
pp. 152660282199672
Author(s):  
Giovanni Tinelli ◽  
Marie Bonnet ◽  
Adrien Hertault ◽  
Simona Sica ◽  
Gian Luca Di Tanna ◽  
...  
Keyword(s):  
Operating Room ◽  
Clinical Outcomes ◽  
Cox Regression ◽  
Statistical Significance ◽  
Aortic Aneurysms ◽  
Study Patient ◽  
Cox Regression Analysis ◽  
Significant Difference ◽  
The Impact

Purpose: Evaluate the impact of hybrid operating room (HOR) guidance on the long-term clinical outcomes following fenestrated and branched endovascular repair (F-BEVAR) for complex aortic aneurysms. Materials and Methods: Prospectively collected registry data were retrospectively analyzed to compare the procedural, short- and long-term outcomes of consecutive F-BEVAR performed from January 2010 to December 2014 under standard mobile C-arm versus hybrid room guidance in a high-volume aortic center. Results: A total of 262 consecutive patients, including 133 patients treated with a mobile C-arm equipped operating room and 129 with a HOR guidance, were enrolled in this study. Patient radiation exposure and contrast media volume were significantly reduced in the HOR group. Short-term clinical outcomes were improved despite higher case complexity in the HOR group, with no statistical significance. At a median follow-up of 63.3 months (Q1 33.4, Q3 75.9) in the C-arm group, and 44.9 months (Q1 25.1, Q3 53.5, p=0.53) in the HOR group, there was no statistically significant difference in terms of target vessel occlusion and limb occlusion. When the endograft involved 3 or more fenestrations and/or branches (complex F-BEVAR), graft instability (36% vs 25%, p=0.035), reintervention on target vessels (20% vs 11%, p=0.019) and total reintervention rates (24% vs 15%, p=0.032) were significantly reduced in the HOR group. The multivariable Cox regression analysis did not show statistically significant differences for long-term death and aortic-related death between the 2 groups. Conclusion: Our study suggests that better long-term clinical outcomes could be observed when performing complex F-BEVAR in the latest generation HOR.

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