scholarly journals Brazilian Propolis: Correlation between Chemical Composition and Antimicrobial Activity

2008 ◽  
Vol 5 (3) ◽  
pp. 317-324 ◽  
Author(s):  
Kelly Salomão ◽  
Paulo Roberto S. Pereira ◽  
Leila C. Campos ◽  
Cintia M. Borba ◽  
Pedro H. Cabello ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Paracoccidioides Brasiliensis ◽  
Sporothrix Schenckii ◽  
Coumaric Acid ◽  
Dicaffeoylquinic Acid ◽  
Group A ◽  
Brazilian Propolis ◽  
Ethanol Extracts ◽  
Group B ◽  
Hydroxycinnamic Acid Derivative

The chemical composition of ethanol extracts from samples of Brazilian propolis (EEPs) determined by HPLC and their activity againstTrypanosoma cruzi,Staphylococcus aureus,Streptococcus pneumoniae,Klebisiella pneumoniae,Candida albicans,Sporothrix schenckiiandParacoccidioides brasiliensiswere determined. Based on the predominant botanical origin in the region of samples' collection, the 10 extracts were separated into three groups: A (B. dracunculifolia+Auraucariaspp), B (B. dracunculifolia) and C (Araucariaspp). Analysis by the multiple regression of all the extracts together showed a positive correlation, higher concentrations leading to higher biological effect, ofS. aureuswithp-coumaric acid (PCUM) and 3-(4-hydroxy-3-(oxo-butenyl)-phenylacrylic acid (DHCA1) and of trypomastigotes ofT. cruziwith 3,5-diprenyl-4-hydroxycinnamic acid derivative 4 (DHCA4) and 2,2-dimethyl-6-carboxyethenyl-2H-1-benzopyran (DCBEN). When the same approach was employed for each group, due to the small number of observations, the statistical test gave unreliable results. However, an overall analysis revealed for group A an association ofS. aureuswith caffeic acid (CAF) and dicaffeoylquinic acid 3 (CAFQ3), ofS. pneumoniaewith CAFQ3 and monocaffeoylquinic acid 2 (CAFQ2) and ofT. cruzialso with CAFQ3. For group B, a higher activity againstS. pneumoniaewas associated DCBEN and forT. cruziwith CAF. For group C no association was observed between the anitmicrobial effect and any component of the extracts. The present study reinforces the relevance of PCUM and derivatives, especially prenylated ones and also of caffeolyquinic acids, on the biological activity of Brazilian propolis.

scholarly journals Chemical Composition of the Same Brazilian Propolis Sample Analyzed in 1997 and in 2012: No Freezing Effect

2015 ◽  
Vol 10 (7) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Bruno José Conti ◽  
Vassya Bankova ◽  
José Maurício Sforcin
Keyword(s):  
Chemical Composition ◽  
Caffeic Acid ◽  
Coumaric Acid ◽  
Brazilian Propolis ◽  
Qualitative Changes

The same propolis sample that was analyzed by GC-MS in 1997 and 2012 was examined again after being frozen for 15 years. No qualitative changes were seen in its composition; artepilin C, prenyl- p-coumaric acid, dihydrocinnamic acid, caffeic acid were the major compounds.

Chemical Composition of Brazilian Propolis from Sao Paulo State

1998 ◽  
Vol 53 (1-2) ◽  
pp. 117-119 ◽  
Author(s):  
M. C. Marcucci ◽  
Jose Rodriguez ◽  
F. Ferreres ◽  
V. Bankova ◽  
Robson Groto ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Sao Paulo ◽  
The Other ◽  
São Paulo ◽  
Qualitative Composition ◽  
Coumaric Acid ◽  
Paulo State ◽  
São Paulo State ◽  
Brazilian Propolis

Abstract Two propolis samples from Sao Paulo State were investigated by GC/MS. 39 compounds were identified, 8 being new for propolis. Both samples showed some similarities in their qualitative composition. In one of them, coumaric acid and its prenylated derivatives predo­minated, while in the other one triterpenic alcolhols were the main constituents.

A comparative assessment of effects of Polish propolis combined with plant oils with those of Brazilian propolis on the oral cavity condition in ortofacial cleft patients treated with removable appliances

2017 ◽  
Vol 13 (1) ◽  
pp. 5-27
Author(s):  
Agnieszka Machorowska-Pieniążek ◽  
Marta Tanasiewicz ◽  
Małgorzata Skucha-Nowak ◽  
Tadeusz Morawiec
Keyword(s):  
Oral Cavity ◽  
Cleft Lip ◽  
Ethanol Extract ◽  
Comparative Assessment ◽  
Plant Oils ◽  
Orofacial Cleft ◽  
Group A ◽  
Brazilian Propolis ◽  
Group B ◽  
Removable Appliances

In patients with orofacial cleft, toothpaste they use should demonstrate anti-inflammatory, antibacterial and regenerative action and at the same time be well-tolerated by the oral cavity epithelium and characterized by low toxicity. For this reason, it is expedient to seek preparations that would show the properties described above and could be used as auxiliary means supporting the maintenance of oral health in patients with orofacial clefts. Aim. The aim of the study was to perform a comparative assessment of toothpaste containing Polish propolis in combination with plant oils with that containing Brazilian propolis on the oral cavity condition in patients with orofacial cleft treated with removable appliances. Material and methods. The study material included 75 patients eligible for the study with a cleft lip or cleft lip and palate treated orthodontically. They were divided into three groups, A, B and C. Group A received a toothpaste with 2 % ethanol extract of Polish propolis (EEP-P) and plant oils, 0.5% tea tree oil (TTO), 0.2% menthol oil (MO), and 0.1% rosemary oil (RO). Group B received a toothpaste with 3% ethanol extract of Brazilian propolis (EEP-B). Group C included patients who were given a placebo toothpaste devoid of any active substances. During the baseline (first) and a follow-up (final) examination after 35 days, in each patient the Approximate Plaque Index (API), gingival index (GI) and Bleeding on Probing (BOP) were assessed. Results. The biggest improvement of the gingival condition translated into the GI index and the BOP was found in group A and amounted to 31% and 26% respectively, compared to the baseline examination (p<0.00); a statistically significant reduction of the GI index by 25% and BOP by 29% (p<0.01) was found in group B. No statistically significant differences of the values of the API, GI and BOP indices were found between groups A and B. There was no significant improvement of the gingiva condition in Group C. Conclusions. Both types of toothpaste containing active substances have beneficial effects on the condition of the marginal parodontium and they do not significantly differ in terms of their biological activity in the oral cavity. Besides, the toothpaste with Polish propolis and plant oils has a beneficial effect on the oral cavity hygiene in children with orofacial cleft. (Machorowska-Pieniążek A, Tanasiewicz M, Skucha-Nowak M, Morawiec T. A comparative assessment of effects of Polish propolis combined with plant oils with those of Brazilian propolis on the oral cavity condition in orofacial cleft patients treated with removable appliances. Orthod Forum 2017; 13: 15-27).

scholarly journals Effect of timing of food deprivation on host resistance to fungal infection in mice

2002 ◽  
Vol 88 (2) ◽  
pp. 151-158 ◽  
Author(s):  
Motoko Oarada ◽  
Takeshi Nikawa ◽  
Nobuyuki Kurita
Keyword(s):  
Food Deprivation ◽  
Host Resistance ◽  
Paracoccidioides Brasiliensis ◽  
Interferon Γ ◽  
Infection Group ◽  
Corticosterone Concentration ◽  
Group A ◽  
Time Of Infection ◽  
Rapid Restoration ◽  
Group B

Mice were deprived of food for a period of 72h at varying times relative to the time of infection withParacoccidioides brasiliensis.Host resistance was diminished profoundly when the period of food deprivation was from 48h before to 24h after infection (group B). When food deprivation was initiated immediately after infection (group C), host resistance was reduced less profoundly. When food deprivation was initiated at 24 and 48h post-infection, reductions in host resistance were only moderate or not observed respectively. These results suggest that the earlier in the course of infection starvation occurs, the more profoundly host resistance is impaired. When food deprivation was initiated 72h before infection, finishing at the time of infection (group A), the reduction in host resistance was considerably less profound compared with group B mice, suggesting that refeeding initiated immediately after infection is responsible for rapid restoration of the antifungal resistance in starved mice. Infection-induced responses of corticosterone and interferon-γ were changed according to the timing of food deprivation. Group A mice, similar to non-fasted controls, showed an infection-induced increase in serum corticosterone concentration, while groups B and C did not. Group C mice showed a substantially greater infection-induced increase in serum interferon-γ compared with the other fasted and non-fasted control groups.

scholarly journals Mineralogy and Chemical Composition of Basalt Stone Tools in Some Iraqi Archaeological Sites

2021 ◽  
Vol 54 (1C) ◽  
pp. 101-113
Author(s):  
Aqeel Al-Zubaidy
Keyword(s):  
Chemical Composition ◽  
Olivine Basalt ◽  
Stone Tools ◽  
Archaeological Sites ◽  
Source Areas ◽  
Two Samples ◽  
Group A ◽  
Vesicular Basalt ◽  
Trade Route ◽  
Group B

Basalt stone tools were collected from some Iraqi Archaeological Sites. Twenty-one samples were studied petrographically, mineralogically, and chemical composition. Five samples were from the Gaara Depression north of Rutba town, seven samples from Tarmiya, north Baghdad, seven samples from Dalmij site, east of Diwaniya city, and two samples from Jordan, which were used for comparison. The studied samples were classified into three groups, according to their mineralogy and texture: Group A: Vesicular Basalt, Group B: Dolerite, and Group C: Olivine Basalt. These stones most probably were used as a hand axe, grinder, hammer, and other uses, as well as for buildings, like those used in Qasar Al- Azraq and Umm Al- Jamal archaeological sites in Jordan. These basalt rocks most probably were transported by an ancient man from Harrat Al-Sham, which extends through Syria-Jordan-Saudi Arabia, or from NE Syria through a trade route that connected between source areas and the studied archaeological sites in Iraq.

scholarly journals Characteristics of Particles and Debris Released after Implantoplasty: A Comparative Study

Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 602
Author(s):  
Xixi Wu ◽  
Changjie Cai ◽  
Javier Gil ◽  
Elizabeth Jantz ◽  
Yacoub Al Sakka ◽  
...  
Keyword(s):  
Electron Microscope ◽  
Chemical Composition ◽  
Scanning Electron Microscope ◽  
Surface Area ◽  
Particle Number ◽  
Significant Difference ◽  
Group A ◽  
Particle Sizer ◽  
Group B ◽  
Scanning Electron

Titanium particles embedded on peri-implant tissues are associated with a variety of detrimental effects. Given that the characteristics of these detached fragments (size, concentration, etc.) dictate the potential cytotoxicity and biological repercussions exerted, it is of paramount importance to investigate the properties of these debris. This study compares the characteristics of particles released among different implant systems (Group A: Straumann, Group B: BioHorizons and Group C: Zimmer) during implantoplasty. A novel experimental system was utilized for measuring and collecting particles generated from implantoplasty. A scanning mobility particle sizer, aerodynamic particle sizer, nano micro-orifice uniform deposit impactor, and scanning electron microscope were used to collect and analyze the particles by size. The chemical composition of the particles was analyzed by highly sensitive microanalysis, microstructures by scanning electron microscope and the mechanical properties by nanoindentation equipment. Particles released by implantoplasty showed bimodal size distributions, with the majority of particles in the ultrafine size range (<100 nm) for all groups. Statistical analysis indicated a significant difference among all implant systems in terms of the particle number size distribution (p < 0.0001), with the highest concentration in Group B and lowest in Group C, in both fine and ultrafine modes. Significant differences among all groups (p < 0.0001) were also observed for the other two metrics, with the highest concentration of particle mass and surface area in Group B and lowest in Group C, in both fine and ultrafine modes. For coarse particles (>1 µm), no significant difference was detected among groups in terms of particle number or mass, but a significantly smaller surface area was found in Group A as compared to Group B (p = 0.02) and Group C (p = 0.005). The 1 first minute of procedures had a higher number concentration compared to the second and third minutes. SEM-EDS analysis showed different morphologies for various implant systems. These results can be explained by the differences in the chemical composition and microstructures of the different dental implants. Group B is softer than Groups A and C due to the laser treatment in the neck producing an increase of the grain size. The hardest implants were those of Group C due to the cold-strained titanium alloy, and consequently they displayed lower release than Groups A and B. Implantoplasty was associated with debris particle release, with the majority of particles at nanometric dimensions. BioHorizons implants released more particles compared to Straumann and Zimmer. Due to the widespread use of implantoplasty, it is of key importance to understand the characteristics of the generated debris. This is the first study to detect, quantify and analyze the debris/particles released from dental implants during implantoplasty including the full range of particle sizes, including both micro- and nano-scales.

scholarly journals Adrenal function in 23 children with paracoccidioidomycosis

2006 ◽  
Vol 48 (6) ◽  
pp. 333-336 ◽  
Author(s):  
Ricardo Mendes Pereira ◽  
Gil Guerra-Júnior ◽  
Antonia Terezinha Tresoldi
Keyword(s):  
Paracoccidioides Brasiliensis ◽  
Adrenal Function ◽  
Renin Activity ◽  
Acth Test ◽  
Normal Range ◽  
End Of Treatment ◽  
Group A ◽  
Group B ◽  
Sodium And Potassium ◽  
Systemic Form

Adrenal involvement by Paracoccidioides brasiliensis was described at necropsies and in many clinical studies, but only in adults. Therefore, the aim of this study was to evaluate adrenal function in children with paracoccidioidomycosis. Twenty-three children with the systemic form of paracoccidioidomycosis were evaluated and divided in two Groups: Group A (n = 8) included children before treatment and Group B (n = 15) children after the end of treatment. Plasma cortisol (basal and after ACTH test), ACTH, renin activity, aldosterone, sodium and potassium were measured. They were within normal range in all cases, except for renin activity and aldosterone, which were elevated in some cases. Group A patients showed basal and post-ACTH cortisol levels significantly greater than Group B patients. The results showed that adrenal function was not compromised in these children with paracoccidioidomycosis.

An ultrastructural study of sertoli cells in two geographically isolated populations of Aphanius dispar

1992 ◽  
Vol 50 (1) ◽  
pp. 548-549
Author(s):  
Taber A. Ba-Omar ◽  
Philip F. Prentis
Keyword(s):  
Ultrastructural Level ◽  
Uranyl Acetate ◽  
Freshwater Teleost ◽  
Isolated Populations ◽  
En Bloc ◽  
The North ◽  
Group A ◽  
Ultrathin Sections ◽  
Group B ◽  
Geographically Isolated

We have recently carried out a study of spermiogenic differentiation in two geographically isolated populations of Aphanius dispar (freshwater teleost), with a view to ascertaining variation at the ultrastructural level. The sampling areas were the Jebel Al Akhdar in the north (Group A) and the Dhofar region (Group B) in the south. Specimens from each group were collected, the testes removed, fixed in Karnovsky solution, post fixed in OsO, en bloc stained with uranyl acetate and then routinely processed to Agar 100 resin, semi and ultrathin sections were prepared for study.

Comparison of one-year prognosis of patients classified as chronic critical lower limb ischaemia according to TASC II or European consensus definition in the COPART cohort

VASA ◽  
2015 ◽  
Vol 44 (3) ◽  
pp. 0220-0228 ◽  
Author(s):  
Marion Vircoulon ◽  
Carine Boulon ◽  
Ileana Desormais ◽  
Philippe Lacroix ◽  
Victor Aboyans ◽  
...  
Keyword(s):  
Medical Treatment ◽  
Critical Limb Ischaemia ◽  
Limb Ischaemia ◽  
Medical Group ◽  
Consensus Definition ◽  
Transcutaneous Oxygen ◽  
European Consensus ◽  
Group A ◽  
One Year ◽  
Group B

Background: We compared one-year amputation and survival rates in patients fulfilling 1991 European consensus critical limb ischaemia (CLI) definition to those clas, sified as CLI by TASC II but not European consensus (EC) definition. Patients and methods: Patients were selected from the COPART cohort of hospitalized patients with peripheral occlusive arterial disease suffering from lower extremity rest pain or ulcer and who completed one-year follow-up. Ankle and toe systolic pressures and transcutaneous oxygen pressure were measured. The patients were classified into two groups: those who could benefit from revascularization and those who could not (medical group). Within these groups, patients were separated into those who had CLI according to the European consensus definition (EC + TASC II: group A if revascularization, group C if medical treatment) and those who had no CLI by the European definition but who had CLI according to the TASC II definition (TASC: group B if revascularization and D if medical treatment). Results: 471 patients were included in the study (236 in the surgical group, 235 in the medical group). There was no difference according to the CLI definition for survival or cardiovascular event-free survival. However, major amputations were more frequent in group A than in group B (25 vs 12 %, p = 0.046) and in group C than in group D (38 vs 20 %, p = 0.004). Conclusions: Major amputation is twice as frequent in patients with CLI according to the historical European consensus definition than in those classified to the TASC II definition but not the EC. Caution is required when comparing results of recent series to historical controls. The TASC II definition of CLI is too wide to compare patients from clinical trials so we suggest separating these patients into two different stages: permanent (TASC II but not EC definition) and critical ischaemia (TASC II and EC definition).

Absorbable suture material in carotid surgery

VASA ◽  
2015 ◽  
Vol 44 (6) ◽  
pp. 451-457 ◽  
Author(s):  
Vincenzo Gasbarro ◽  
Luca Traina ◽  
Francesco Mascoli ◽  
Vincenzo Coscia ◽  
Gianluca Buffone ◽  
...  
Keyword(s):  
Suture Material ◽  
Absorbable Suture ◽  
Paediatric Surgery ◽  
Carotid Surgery ◽  
Suture Materials ◽  
Absorbable Suture Material ◽  
Absorbable Sutures ◽  
Group A ◽  
Group B

Abstract. Background: Absorbable sutures are not generally accepted by most vascular surgeons for the fear of breakage of the suture line and the risk of aneurysmal formation, except in cases of paediatric surgery or in case of infections. Aim of this study is to provide evidence of safety and efficacy of the use of absorbable suture materials in carotid surgery. Patients and methods: In an 11 year period, 1126 patients (659 male [58.5 %], 467 female [41.5 %], median age 72) underwent carotid endarterectomy for carotid stenosis by either conventional with primary closure (cCEA) or eversion (eCEA) techniques. Patients were randomised into two groups according to the type of suture material used. In Group A, absorbable suture material (polyglycolic acid) was used and in Group B non-absorbable suture material (polypropylene) was used. Primary end-point was to compare severe restenosis and aneurysmal formation rates between the two groups of patients. For statistical analysis only cases with a minimum period of follow-up of 12 months were considered. Results: A total of 868 surgical procedures were considered for data analysis. Median follow-up was 6 years (range 1-10 years). The rate of postoperative complications was better for group A for both cCEA and eCEA procedures: 3.5 % and 2.0 % for group A, respectively, and 11.8 % and 12.9 % for group B, respectively. Conclusions: In carotid surgery, the use of absorbable suture material seems to be safe and effective and with a general lower complications rate compared to the use of non-absorbable materials.

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