P205 Influencing factors of Sleep quality in patients with Crohn’s Disease

Abstract Background Sleep is considered vital for the health and quality of life of individuals. Recently, studies have suggested that sleep disturbances are common in people with Crohn’s disease (CD) and in the majority of cases are related to disease activity.The aim of our study was to determine the prevalence of insomnia in patients with CD and to identify the influencing factors. Methods A prospective cross-sectional study including patients with CD followed in the department between July and August 2020 was carried out. Epidemiological and clinical data have been collected. Self-report questionnaires were given to patients. Insomnia was assessed using the Insomnia Severity Index (ISI) which provides a valid index of the overall severity of insomnia. A score between 0 and 7 indicates the absence of insomnia; between 8 and 14 a mild infra-clinical insomnia; between 15 and 21 moderate clinical insomnia, and between 22 and 28 severe insomnia. Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS) questionnaire which is a scale of 14 items rated from 0 to 3. Seven questions are related to anxiety and seven to depression. Fatigue was screened for using the Fatigue Severity Scale (FSS) which has 9 questions rated from one to seven. Significant fatigue was defined by a score greater than or equal to 5.5. Statistical analysis was performed by SPSS 21 software (p significant if less than 0.05). Results Thirty two patients with a mean age of 38.28 years [18–60 years] and a sex ratio equal to 1 were enrolled. Mean duration of the disease was 10.56 years [1–40 years]. At the time of inclusion, the average Harvey Bradshaw (HAB) score was 5.14 [1–14]. Mean insomnia score was 12.62 [0–26]. The insomnia severity index showed mild insomnia in 4 patients (12.5%), moderate insomnia in 7 patients (22%) and severe insomnia in 8 patients (25%). The HADS score revealed obvious depression in 19% of patients, doubtful depression in 25% of patients. 56% of patients had no symptoms of depression. Likewise, anxiety was objectified in 22% of patients and doubtful anxiety in 37% of patients. 41% of patients had no symptoms of anxiety. The mean fatigue score was 3.75 ± 1.9 [range 1–9]. A fatigue score greater than or equal to 5.5 was observed in 3 cases (9%). A significant positive correlation was found between the insomnia severity score and the depression score (r = 0.4, p = 0.035) as well as the fatigue severity score (r: 0.36, p = 0.04). Conclusion Our study shows that insomnia is very common in patients with CD. The factors associated with these sleep disturbances were depression and fatigue. Gastroenterologist and psychologist should join forces to evaluate emotional as well as sleep disturbances for a better global CD management.

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Sleep Disturbances in Individuals Quarantined Due to SARS-CoV-2 Pandemic in Poland: A Mixed Methods Design Study

Global Advances in Health and Medicine ◽

10.1177/21649561211020707 ◽

2021 ◽

Vol 10 ◽

pp. 216495612110207

Author(s):

Sabina Krupa ◽

Witt Paweł ◽

Wioletta Mędrzycka-Dąbrowska ◽

Agnieszka Lintowska ◽

Dorota Ozga

Keyword(s):

Mixed Methods ◽

Sleep Disturbances ◽

Acute Stress ◽

Sleep Problems ◽

Severity Index ◽

Structured Interview ◽

Mixed Methods Design ◽

Design Study ◽

Insomnia Severity Index ◽

Insomnia Severity

Objectives The study aimed to assess sleep disturbances in patients subjected to home quarantine due to suspected SARS-CoV-2 infection. The study used a mixed methods design study as a research methodology. Methods A semi-structured interview and the scale for Insomnia Severity Index (ISI) were used to achieve the aim of the study. The survey was conducted from 16 to 20 April 2020 and 1 to 2 September 2020 in Poland, at the during of SARS-CoV-2 epidemic in this country. The data were coded and cross-processed. The (COREQ) checklist was followed. Results Interviews with patients and a thorough analysis of recordings revealed commonly used phrases in the following categories: “anxiety”, “ Am I going crazy?”, “Sleep problems”. 10 out of 11 respondents reported sleep disorders of varying severity according to the Insomnia Severity Index scale. Patients presented a fear related to the return to society and normal functioning after quarantine. Additionally, some study participants voiced concerns related to their mental health; some cases of hallucinations were reported. Conclusions Further global population studies should be conducted to analyse this phenomenon. Acute Stress Disorder should be understood as a threat to life and health of an isolated society in quarantine. Further research in this area should be promoted and the need for global guidelines for the entire population should be developed.

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Evaluation of habitual sleep and factors influencing it in patients awaiting acute or planned abdominal surgery

Gastrointestinal Nursing ◽

10.12968/gasn.2021.19.8.28 ◽

2021 ◽

Vol 19 (8) ◽

pp. 28-34

Author(s):

Marian Christin Petersen ◽

Ismail Gögenur

Keyword(s):

Abdominal Surgery ◽

Epworth Sleepiness Scale ◽

Sleep Disturbances ◽

Sleep Problems ◽

Negative Impact ◽

Severity Index ◽

Study Cohort ◽

Insomnia Severity Index ◽

Female Sex ◽

Insomnia Severity

Background and aims: This study aimed to clarify the incidence and severity of habitual sleep disturbances in patients undergoing surgery. Methods: A survey was conducted to collect data in a cohort of patients awaiting abdominal surgery. The Insomnia Severity Index score was used as primary measurement, while the Epworth Sleepiness Scale and Pittsburgh Sleep Quality Index scores were used as secondary measurements. Findings: Overall, 119 patients were included in the analysis. The habitual sleep in the study cohort revealed high incidence of sleep difficulties and insomnia. Female sex and incidence of anxiety and depression were significantly related to all three scores, while age and employment were associated with Epworth Sleepiness Scale and Insomnia Severity Index scores, respectively. Conclusions: Female sex, experiencing depression or anxiety had severe negative impact on sleep in patients scheduled for elective or planned surgery. The prevalence of sleep problems in patients should be considered for optimising sleep to improve rehabilitation and reduce stress associated with surgery.

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1126 Relationship Between Headache and Sleep: A Longitudinal Study from the Population of Sao Paulo City (Brazil)

SLEEP ◽

10.1093/sleep/zsaa056.1120 ◽

2020 ◽

Vol 43 (Supplement_1) ◽

pp. A428-A429

Author(s):

L M Lucchesi ◽

P F Tempaku ◽

A A Smith ◽

S Togeiro ◽

H Hachul ◽

...

Keyword(s):

Longitudinal Study ◽

Sleep Disturbances ◽

Severity Index ◽

Sao Paulo ◽

Anxiety And Depression ◽

São Paulo ◽

Follow Up Studies ◽

Nocturnal Awakening ◽

Insomnia Severity

Abstract Introduction The complaint of nocturnal awakening with headache (NAH), was prevalent (8.4%) in the São Paulo population and was associated with sleep disturbances, as demonstrated in a study conducted in 2007 (EPISONO). Indeed, this relationship between sleep and headache is well documented in the literature. Objective: To assess the incidence and evolution of NAH and to associate sleep-related variables in an eight-year prospective study. Methods From 1042 volunteers enrolled in the baseline, 712 agreed to participate in the follow-up. Questionnaires and scales were applied and polysomnography and actigraphy performed. The complaint of NAH was analyzed according to a frequency questionnaire and separated into frequent or occasional. Results At follow-up, 110 volunteers reported NAH, of which 82 were the same as those from the baseline, but only 38 had frequent complaints. Comparing with volunteers whose headache has become occasional, we have as a difference the insomnia severity index which is significantly higher in the group with frequent NAH (8.40 ± 5.10 vs 11.20±6.40 p:0.03) and worse sleep quality as measured by the Pittsburgh questionnaire (7.25±3.60 vs 10.25±4.60 p:0.002). In addition, these volunteers had higher anxiety (10.40±9.30 vs 12.00± 10:00 p: 0.008) and depression (10.60±9.90 vs 12:00±9.90 p:0.005) from Beck’s questionnaires and greater fatigue (4.85±3.10 vs 9.75±5.55 p:0.001). The associations of NAH with insomnia, nightmares, and bruxism observed in the baseline continued, but no difference was observed between those who had frequent or occasional complaints at follow-up. Conclusion Our study showed that NAH was highly prevalent in the Sao Paulo population in both the baseline and follow-up studies, but this frequency had a reduction in follow-up. Volunteers who persisted with the frequent complaint showed greater severity of insomnia, higher anxiety and depression and greater fatigue. Support Associação Fundo de Incentivo à Pesquisa (AFIP) and São Paulo Research Foundation (FAPESP)

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Validation of the Insomnia Severity Index (ISI) for identifying insomnia in young adult cancer survivors: comparison with a structured clinical diagnostic interview of the DSM-5 (SCID-5)

Sleep Medicine ◽

10.1016/j.sleep.2021.01.045 ◽

2021 ◽

Vol 81 ◽

pp. 80-85

Author(s):

Alexis L. Michaud ◽

Eric S. Zhou ◽

Grace Chang ◽

Christopher J. Recklitis

Keyword(s):

Young Adult ◽

Cancer Survivors ◽

Severity Index ◽

Diagnostic Interview ◽

Insomnia Severity Index ◽

Young Adult Cancer Survivors ◽

Dsm 5 ◽

Adult Cancer Survivors ◽

Young Adult Cancer ◽

Insomnia Severity

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The Relationship Between Smartphone Use, Insomnia, Stress, and Anxiety Among University Students: A Cross-Sectional Study

Clinical Nursing Research ◽

10.1177/1054773820983161 ◽

2020 ◽

pp. 105477382098316

Author(s):

Nisreen Al Battashi ◽

Omar Al Omari ◽

Murad Sawalha ◽

Safiya Al Maktoumi ◽

Ahmed Alsuleitini ◽

...

Keyword(s):

University Students ◽

Severity Index ◽

Depression Anxiety Stress Scale ◽

Cross Sectional ◽

Convenience Sample ◽

Insomnia Severity Index ◽

Stress Scale ◽

Smartphone Use ◽

The Relationship ◽

Insomnia Severity

The rapid increase in the number of smartphone users has raised concern about the negative psychosocial and physical effects of this use. A descriptive cross-sectional design was conducted to investigate the relationship between smartphone use, anxiety and insomnia among university students. A convenience sample of 404 students from one public university completed questionnaires with items from the Smartphone Addiction Scale, the Depression Anxiety Stress Scale and the Insomnia Severity Index, with some demographic data. High smartphone addition scale score was significantly associated with higher anxiety and stress scores of the Depression Anxiety Stress scale, and higher insomnia severity index score. The findings support the importance of an intervention program to promote appropriate use of smartphones and to improve sleep and psychological symptoms such as stress and anxiety among university students.

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Mapping of the Insomnia Severity Index and other sleep measures to EuroQol EQ-5D health state utilities

Health and Quality of Life Outcomes ◽

10.1186/1477-7525-9-119 ◽

2011 ◽

Vol 9 (1) ◽

pp. 119 ◽

Cited By ~ 7

Author(s):

Ning Yan Gu ◽

Marc F Botteman ◽

Xiang Ji ◽

Christopher F Bell ◽

John A Carter ◽

...

Keyword(s):

Severity Index ◽

Health State ◽

Insomnia Severity Index ◽

Health State Utilities ◽

Insomnia Severity

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Changes in sleep predict changes in depressive symptoms in depressed subjects receiving vortioxetine: An open-label clinical trial

Journal of Psychopharmacology ◽

10.1177/0269881119874485 ◽

2019 ◽

Vol 33 (11) ◽

pp. 1388-1394 ◽

Cited By ~ 3

Author(s):

Bing Cao ◽

Caroline Park ◽

Joshua D Rosenblat ◽

Yan Chen ◽

Michelle Iacobucci ◽

...

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Sleep Quality ◽

Epworth Sleepiness Scale ◽

Quality Index ◽

Pittsburgh Sleep Quality Index ◽

Severity Index ◽

Major Depressive ◽

Insomnia Severity Index ◽

Insomnia Severity

Background Sleep disturbances are frequently reported in patients with major depressive disorder. We aimed to investigate the effects of vortioxetine on sleep quality and association between changes in sleep and treatment response. Methods: This study is a post-hoc analysis of a clinical trial that sought to evaluate the sensitivity to cognitive change of THINC-integrated tool in patients with major depressive disorder. In total, 92 patients (aged 18 to 65) meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria for moderate or severe major depressive disorder and 54 healthy controls were included. All patients received open-label vortioxetine (10–20 mg/day, flexibly dosed) for 8 weeks. Herein, the primary outcomes of interest were changes in sleep, as measured by the Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale and Insomnia Severity Index, between weeks 0, 2, and 8. The association between changes in sleep and depressive symptom severity was secondarily assessed. Results: We observed that sleep, as indicated by scores of Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale and Insomnia Severity Index, was significantly poorer in patients with major depressive disorder compared to healthy controls at weeks 0, 2, and 8 ( p < 0.05). Among patients with major depressive disorder, we observed significant improvements on the Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale and Insomnia Severity Index between weeks 0 and 8 ( p < 0.05). We observed a significant association between improvements on the Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, and Insomnia Severity Index and improvement of depressive symptoms. Conclusion: Improvement of depressive symptoms in major depressive disorder patients treated with vortioxetine was associated with significant improvements in sleep. Furthermore, improvements in sleep were predictive of antidepressant response and were linearly correlated with improvement in overall depressive symptom severity.

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