P1477 Features of structural and functional parameters of the right and left heart and their relationship with the spirometry parameters in patients with CHF of ischemic genesis with COPD

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
V Evdokimov ◽  
A Evdokimova ◽  
E Yushchuk ◽  
S Ivanova
Keyword(s):  
Respiratory Function ◽  
Anterior Wall ◽  
Diastolic Filling ◽  
External Respiration ◽  
Left Heart ◽  
Functional Parameters ◽  
Sphericity Index ◽  
Left And Right ◽  
The Right ◽  
The Relationship

Abstract Purpose Сomparative analysis of structural and functional parameters of the heart, the state of external respiration in patients with CHF II-III FC of ischemic genesis in the absence and in combination with moderate to severe COPD. Material and methods The study included patients aged 65.6 ± 3.9 years with LVEF ≤ 45% (according to Simpson). The first group consisted of 87 patients with CHF of ischemic genesis, and the second group - 385 patients with CHF of ischemic genesis and coexisted COPD. All patients were evaluated for clinical condition, TTE, the study of respiratory function with bronchodilation test. Results Patients of both groups were comparable by sex, age, FC CHF (NYHA). In patients with COPD, linear and volumetric LV parameters exceeded the normal values and were significantly higher than in CHF patients without COPD. LVIMM, LV sphericity index were significantly higher in the group of patients with COPD, which is associated with more pronounced remodeling of the left heart. Correlation analysis showed direct moderate and reliable relationships between the RVIDd (internal end-diastolic diameter) and MPAP (r = 0.68, p < 0.01), RVIDd and LVSV (stroke volume) and FEV1 (r = 0.38, p < 0.05), FEV1 and LVMMI (r = 0.33, p < 0.05), FVC and LVMMI (r = 0.34, p < 0.05), LVEF and FEV1 (r = 0.44, p < 0.05) and VC (lung vital capacity) (r = 0.36, p < 0.05). Negative correlations were found between low-level FEV1 and RVIDd (r=-0.29, p < 0.05), FEV1 and SatO2 (r = 0.28, p < 0.05), and a strong degree between MPAP and FEV1 (r=-0.55, p < 0.05), moderate between MPAP and FEF75 (r=-0.57, p < 0.05). In patients with COPD more pronounced significant increases in RVIDd, MPAP, RA dimension were noted. In patients of this group (n = 385), the IVRT and time of deceleration during the early diastolic filling (DTE) of RV increased more significantly. RV diastolic dysfunction in patients with CHF with COPD may be due to slower relaxation of the right ventricular hypertrophy and an increase in afterload (evidenced by the relationship between the velocity of early diastolic filling (E) of the RV and the thickness of the anterior wall of the RV; the velocity of late filling (A) of the RV and MPAP (r= 0.3, p < 0.05)). Conclusion In patients with CHF of ischemic genesis with COPD, a more pronounced remodeling of the left and right parts of the heart was noted, reliable interrelationships of respiratory function indicators and structural and functional parameters of both the left and right ventricles of the heart were revealed.

Postnatal Development of a Left-Right Atrial Pressure Gradient

1956 ◽  
Vol 186 (3) ◽  
pp. 521-524 ◽  
Author(s):  
A. van Harreveld ◽  
F. E. Russell
Keyword(s):  
Left Ventricle ◽  
Pressure Gradient ◽  
Left Atrium ◽  
Postnatal Development ◽  
Right Atrial ◽  
Left And Right ◽  
The Mean ◽  
The Right ◽  
The Relationship ◽  
Equal Thickness

The mean left and right atrial pressures were measured in six groups of 10 kittens each. One group was examined between the 12th and 24th hour after birth, one group after 3 days, after 1 week, 2 weeks, 1 month and 2 months. The left and right atrial pressures were almost equal in the first group. With age an increasing left to right pressure gradient developed. In the oldest group the pressure in the left atrium was almost twice as great as in the right. Parallel with the pressure gradient a difference developed in the wall thicknesses of the left and right ventricles. At birth the ventricular walls were of about equal thickness; at age 2 months the left ventricle wall was more than twice as thick as the right. The relationship between ventricle wall thicknesses and atrial pressures is discussed.

scholarly journals A Rare Coronary Artery Anomaly: Double Left Anterior Descending Artery

2012 ◽  
Vol 2 ◽  
pp. 83 ◽  
Author(s):  
Guray Oncel ◽  
Dilek Oncel
Keyword(s):  
Computed Tomography ◽  
Coronary Artery ◽  
Multislice Computed Tomography ◽  
Right Ventricular Outflow Tract ◽  
Ventricular Outflow Tract ◽  
Anterior Wall ◽  
Coronary Anomalies ◽  
Left Main ◽  
Left And Right ◽  
The Right

Double left anterior descending coronary artery arising from the left and right coronary arteries is one of the rarest of coronary anomalies. In this report, we present a case of double left anterior descending coronary artery with one originating from the left main stem and the second one originating from the same ostium with the right coronary artery, passing to the left side following an inter-arterial course between aorta and right ventricular outflow tract and spreading to the anterior wall of the left ventricle. The diagnosis was made with multislice computed tomography angiography. To our knowledge, only a few such cases have been published in the literature so far.

scholarly journals P662 Synchrony between the right and left heart systems is recovered after TAVI in patients with severe aortic stenosis

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
T Ota ◽  
Y Murakami ◽  
Y Kozuka ◽  
C Ohshiro ◽  
N Kihara ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Cardiac Function ◽  
Aortic Valve Stenosis ◽  
Speckle Tracking ◽  
Contraction Time ◽  
Left Heart ◽  
Tricuspid Annulus ◽  
Movement Distance ◽  
The Right ◽  
The Relationship

Abstract Funding Acknowledgements Young Investigator Grant of Japanese Society of Cardiovascular Anesthesia Background / Introduction Evidences have shown that cardiac function decline and systolic phase change are caused by massive afterload of the stenosed aortic valve in patients with severe aortic valve stenosis. As a result of the reduction of the left ventricular afterload by valve replacement, the cardiac function recovers. However, it has not been clarified yet how the changes in cardiac function affect the relationship between the right and left heart systems, as well as the systole phase. TAPSE and MAPSE are known as indices of simple cardiac function evaluation by measuring the movement distance of the atrioventricular annulus. We obtained these indices (i.e. TAPSE, MAPSE) within the same heartbeat using speckle tracking analysis of the atrioventricular annulus and evaluated the changes in cardiac function and phase between the right and left heart systems. Purpose To reveal the relationship of cardiac function and time phase between the right and left heart systems by evaluating the maximum movement distance and time of the atrioventricular annulus within the same heartbeat and the same view in patients with severe aortic valve stenosis before and after TAVI. Methods A prospective cohort study was conducted. We recruited and analyzed 44 patients with severe aortic valve stenosis who received TAVI treatment, able to record baseline before treatment and follow-up 6 months and 12 months after treatment at our hospital from March 2017 to May 2019. Patients were excluded if more than 2 degree of atrioventricular valve regurgitation or incomplete data. The apical four-chamber view was used for speckle tracking analysis with the origin of the apical extension and region of interest (ROI) of the mitral annulus and tricuspid annulus. For each patient before treatment, at 6 months and 12 months after treatment, the maximum contraction distance (DM), maximum contraction time (TM) of the mitral valve annulus, maximum contraction distance (DT) and maximum contraction time (TT) of the tricuspid annulus were measured. Maximum contraction distance ratio (DM/ DT) and maximum contraction time ratio (TM/ TT) were calculated. For statistical analysis, t-test and ANOVA were used, and a significance threshold of p <0.05 was applied. Results TM/ TT decreased at 12 months after TAVI, and DM/ DT increased significantly at 6 months and 12 months after TAVI when compared to baseline before treatment. Conclusions In patients with severe aortic valve stenosis, the correction of cardiac function difference between the right and left heart systems occurs from 6 months after TAVI. Moreover, the correction of contraction phase difference between the right and left heart systems at 12 months after TAVI. Thus, the synchrony between the right and left heart system is recovered 12 months after TAVI. Abstract P662 Figure.

scholarly journals Can QRS morphology be used to differentiate between true septal vs. apparently septal lead placement? An analysis of ECG of real mid-septal, apparent mid-septal, and apical pacing

2020 ◽  
Vol 22 (Supplement_F) ◽  
pp. F14-F22
Author(s):  
Anna Mala ◽  
Pavel Osmancik ◽  
Dalibor Herman ◽  
Karol Curila ◽  
Petr Stros ◽  
...  
Keyword(s):  
Transition Zone ◽  
Anterior Wall ◽  
Lead Placement ◽  
Group A ◽  
Qrs Morphology ◽  
Exact Position ◽  
Left And Right ◽  
The Right ◽  
Lead Location ◽  
Ecg Criteria

Abstract The location of the pacemaker lead is based on the shape of the lead on fluoroscopy only, typically in the left and right anterior oblique positions. However, these fluoroscopy criteria are insufficient and many leads apparently considered to be in septum are in fact anchored in anterior wall. Periprocedural ECG could determine the correct lead location. The aim of the current analysis is to characterize ECG criteria associated with a correct position of the right ventricular (RV) lead in the mid-septum. Patients with indications for a pacemaker had the RV lead implanted in the apex (Group A) or mid-septum using the standard fluoroscopic criteria. The exact position of the RV lead was verified using computed tomography. Based on the findings, the mid-septal group was divided into two subgroups: (i) true septum, i.e. lead was found in the mid-septum, and (ii) false septum, i.e. lead was in the adjacent areas (anterior wall, anteroseptal groove). Paced ECGs were acquired from all patients and multiple criteria were analysed. Paced ECGs from 106 patients were analysed (27 in A, 36 in true septum, and 43 in false septum group). Group A had a significantly wider QRS, more left-deviated axis and later transition zone compared with the true septum and false septum groups. There were no differences in presence of q in lead I, or notching in inferior or lateral leads between the three groups. QRS patterns of true septum and false septum groups were similar with only one exception of the transition zone. In the multivariate model, the only ECG parameters associated with correct lead placement in the septum was an earlier transition zone (odds ratio (OR) 2.53, P = 0.001). ECGs can be easily used to differentiate apical pacing from septal or septum-close pacing. The only ECG characteristic that could help to identify true septum lead position was the transition zone in the precordial leads. ClinicalTrials.gov identifier: NCT02412176.

Hippocampal Subfield Volumes and Cognitive Function in Schizophrenia and Mood Disorders

2022 ◽  
pp. 1-11
Author(s):  
Kasumi Yasuda ◽  
Shinichi Yamada ◽  
Shinya Uenishi ◽  
Natsuko Ikeda ◽  
Atsushi Tamaki ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Mood Disorders ◽  
Molecular Layer ◽  
Composite Score ◽  
Major Depressive ◽  
Brief Assessment ◽  
Transition Area ◽  
Left And Right ◽  
The Right ◽  
The Relationship

<b><i>Introduction:</i></b> The hippocampus is relevant to cognitive function in schizophrenia (SCZ) and mood disorder patients. Although not anatomically uniform, it is clearly divided into subfields. This study aimed to elucidate the relationship between hippocampal subfield volume and cognitive function in patients with SCZ, bipolar disorder (BP), and major depressive disorder (MDD). <b><i>Methods:</i></b> The study included 21 patients with SCZ, 22 with BP, and 21 with MDD and 25 healthy controls (HCs). Neurocognitive function was assessed using the Brief Assessment of Cognition in Schizophrenia. We obtained hippocampal subfield volumes using FreeSurfer 6.0. We compared the volumes of the hippocampal subfield between the 4 groups and ascertained correlation between the cognitive composite score and hippocampal subfield volume in each group. <b><i>Results:</i></b> The SCZ group had significantly lower cognitive composite score than the BP, MDD, and HC groups. In the SCZ group, the left and right hippocampus-amygdala transition area and right subiculum and right presubiculum volumes were significantly reduced compared to those in the HC group. The left presubiculum volumes in the SCZ group were significantly reduced compared to those in the MDD group. Subfield volumes did not significantly differ between the BP, MDD, and HC groups. Interestingly, in the SCZ group, volumes of the right CA1, right molecular layer of the hippocampus, and right granule cell and molecular layer of the dentate gyrus were significantly correlated with the cognitive composite score. <b><i>Conclusion:</i></b> Patients with SCZ had poorer cognitive function, which is related to their hippocampal pathology, than those with mood disorders.

Concept and Verbal Ability as Related to the Cerebral Hemispheres

1977 ◽  
Vol 45 (2) ◽  
pp. 555-566 ◽  
Author(s):  
Norman D. Cook
Keyword(s):  
Right Hemisphere ◽  
Verbal Ability ◽  
Cerebral Hemispheres ◽  
Cooperative Interaction ◽  
Goal State ◽  
Error Detector ◽  
Left And Right ◽  
The Right ◽  
The Relationship ◽  
State Functions

A new theory of human brain function is outlined in terms of the cooperative interaction of the cerebral hemispheres. The well-established verbal, symbolic functions of the left hemisphere and the wholistic, spatial functions of the right hemisphere are seen as separate and independent manifestations of the normally integrated verbal-analytic (or “error detector”) and conceptual (or “goal state”) functions of the left and right, respectively. The relationship between the hemispheres is described in terms of the “goal-directed” system of cybernetics and then compared with related ideas previously presented by Dimond, Penfield, and Piaget.

The azygos veins of the Weddell seal, Leptonychotes weddelli (Lesson)

1972 ◽  
Vol 50 (12) ◽  
pp. 1583-1587 ◽  
Author(s):  
A. G. Watson ◽  
David A. Dowd
Keyword(s):  
Blood Flow ◽  
Vena Cava ◽  
Weddell Seal ◽  
Venous System ◽  
Left And Right ◽  
The Right ◽  
Relationship Of ◽  
The Relationship

The azygos venous system of one Weddell seal (Leptonychotes weddelli) has been described. Both left and right azygos trunks were present with segmental anastomoses between them. The right azygos trunk was the larger and opened into the anterior vena cava; the left azygos trunk terminated in the left costocervical vein. At each segmental level the azygos trunks communicated with collecting sinuses into which drained blood from intercostal spaces and the extradural intravertebral vein. These collecting sinuses were themselves connected to each other by longitudinal anastomoses. The relationship of this system to blood flow during diving is briefly discussed.

Sex of the Face in Western Art: Left and Right in Portraits

1994 ◽  
Vol 12 (1) ◽  
pp. 9-18 ◽  
Author(s):  
Dahlia W. Zaidel ◽  
Peter Fitzgerald
Keyword(s):  
Western Art ◽  
Historical Pattern ◽  
The Face ◽  
Left And Right ◽  
The Right ◽  
The Relationship ◽  
Side Bias

The relationship between observers' taste and the sitter's face orientation as function of sitter sex in painted portraits was investigated. The historical tendency in portraiture is that the sitter's left side of the face is more likely than the right to be turned towards the viewer and this side bias is stronger with women than with men. Correctly oriented and reversed museum portraits were viewed by subjects who gave ratings of “liking” the portrait as a whole (Experiment 1) and for “attractiveness” of the sitter (Experiment 2). Only portraits of women showed a left-right difference with right favored significantly over left, irrespective of orientation or type of rating. These findings go against the historical pattern of the sex-related bias in portraiture. They suggest that most women are painted in an orientation which is less favorable to them.

Persistence of the left superior caval vein: can it potentiate obstructive lesions of the left ventricle?

1999 ◽  
Vol 9 (3) ◽  
pp. 285-290 ◽  
Author(s):  
Gabriella Agnoletti ◽  
Francesco Annecchino ◽  
Laura Preda ◽  
Adele Borghi
Keyword(s):  
Left Ventricle ◽  
Left Ventricular ◽  
Subaortic Stenosis ◽  
Left Heart ◽  
Caval Vein ◽  
Superior Caval Vein ◽  
High Incidence ◽  
Left And Right ◽  
The Right ◽  
Left Heart Syndrome

AbstractRecent evidence has suggested that persistence of the left superior caval vein is associated with a high incidence of obstructive lesions of the left heart. To shed more light on this issue 1085 patients with congenital heart disease were studied retrospectively, with the aim of estimating the prevalence of a persistent left superior caval vein and its associated anomalies, focusing attention on obstructive lesions in the left and right ventricles. Patients with isomerism of the atrial appendages, or hypoplastic left heart syndrome, were excluded. A persisting left superior caval vein was present in 57 patients (5.2%). The overall incidence of obstructive lesions of the left heart was higher in patients with than in those without a persistent left superior caval vein (31.6 versus 7.8%,p< 0.001). Relative hypoplasia of the left ventricle was also higher in patients with persistent left superior caval vein (14 versus 0.8%,p< 0.001). The obstructive lesions found in the left heart, compared with the number in those without a left caval vein, were: mitral stenosis, 5.2 versus 0.7%; subaortic stenosis, 5.3 versus 0.9%; aortic coarctation, 17.5 versus 5.8% (p< 0.01); all of these in association, 3.5 versus 0.4%. In contrast, the incidence of obstructive lesions of the right heart was similar in the two groups of patients. It is concluded that persistence of the left superior caval vein can perturb the normal development of the left ventricle, being strongly associated with obstructions to left ventricular inflow and outflow.

Different Stroke Volumes for the Left and Right Ventricles in the Moving-Actuator Type Total Artificial Heart

1993 ◽  
Vol 16 (1) ◽  
pp. 45-50 ◽  
Author(s):  
B. Min ◽  
I. Kim ◽  
H. Kim
Keyword(s):  
Stroke Volume ◽  
Artificial Heart ◽  
Total Artificial Heart ◽  
Right Atrial ◽  
Diastolic Filling ◽  
Imbalance Problem ◽  
Mock Circulation ◽  
Left And Right ◽  
The Right ◽  
Pressure Changes

A new electromechanical moving-actuator type total artificial heart (TAH) has been developed to solve the imbalance problem without an extra compliance chamber. A different stroke volume was achieved by the large left sac size and the asymmetry of the actuator motion referred to the center position. The left ventricle consists of a double sac with the outer sac attached to the actuator providing active diastolic filling, while the double sac of the right ventricle being free from the actuator, and having sufficient suction produced due to the rigid pump housing. The stroke volume difference between the left and right sac is compensated through the air in the interventricular space of the variable volume (VV) space. Computer simulation based on the geometrical relationships between the blood sacs and the actuator was performed to simulate the physical mechanisms of the moving-actuator type TAH. Results were then compared with the measured pressure changes in various chambers of the pump and the stroke volume differences in mock circulation test. In two acute calf experiments, the balanced left and right atrial pressures were achieved in the moving-actuator type TAH without an extra compliance chamber

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