scholarly journals Life Course Pathways From Childhood SES to Age-Related Declines in Kidney Function Across Adulthood

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 832-832
Author(s):  
Agus Surachman ◽  
Alexis Santos ◽  
Jonathan Daw ◽  
Lacy Alexander ◽  
Christopher Coe ◽  
...  

Abstract Age is a strong predictor of declines in kidney function across adulthood. Using data from 2,045 adults (ages 25-84) in the Midlife in the United States (MIDUS) study, we examined the life course pathways through which low parental education, through adult SES and body mass index (BMI), was associated with faster age-related declines in kidney function. Kidney function declines by 0.8 mL/min/1.73 m2 per year across adulthood. Lower parental education, through adult SES and BMI, was associated with higher kidney function among younger adults (Est = -1.61, SE = 0.62, 95%CI = -2.62, -0.60), but lower kidney function among older adults (Est = 0.93, SE = 0.51, 95%CI = 0.11, 1.79). The impact of early socioeconomic adversity on kidney function is initiated by kidney hyperfiltration in early adulthood and followed by faster declines and development into disease state in later adulthood.

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S191-S191
Author(s):  
Roland J Thorpe ◽  
Carl V Hill

Abstract There is a paucity of research that seeks to understand why race disparities in health across the life course remain elusive. Two such explanations that have been garnering attention is stress and discrimination. This symposium contains papers seeking to address the impact of discrimination or stress on health or health disparities across the life course. First, Brown and colleagues examine black-white differences in the number of reported chronic stressors across five domains their appraised stressfulness, and their varying associations with anxiety and depression among a diverse sample of older adults using data from 6,019 adults ages 52+ from the 2006 HRS. Race and appraisal interactions show that blacks and whites report similar increases in anxiety and depressive symptoms with appraisal. Second, Tobin and colleagues investigate the impact of early life racial discrimination (ELRD) on mental health among Black adults. Using data from 618 participants in the Nashville Stress and Health Study, these investigators found that childhood and adolescent ELRD were positively associated with adult distress. Also, individuals who experienced childhood ERLD had 88% lower odds of adult MDD than individuals with no ELRD. Cobb and colleagues examine the cross-sectional association between everyday discrimination and kidney function among older adults in HRS. The authors report that after adjusting for demographic characteristics, everyday discrimination was associated with lower mean eGFR. The relationship between everyday discrimination and kidney function was not explained by biospsychosocial factors. This collection of papers provides insights into how discrimination or stress impacts health in middle to late life.


2021 ◽  
pp. 105291
Author(s):  
Agus Surachman ◽  
Alexis R. Santos ◽  
Jonathan K. Daw ◽  
Lacy Alexander ◽  
David M. Almeida ◽  
...  

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S128-S129
Author(s):  
Melanie S Hill ◽  
James E Hill ◽  
Stephanie Richardson ◽  
Jessica Brown ◽  
Jeremy B Yorgason ◽  
...  

Abstract Identity scholars have suggested that having a unified sense of past, present, and future is related to positive well-being outcomes (Whitbourne, Sneed & Skultety, 2009). One’s occupation can have a profound influence on an individual’s identity throughout the life course (Nazar & van der Heijden, 2012). Research has looked at career mobility among younger age groups (Baiyun, Ramkissoon, Greenwood, & Hoyte, 2018); however, less is known about the impact of career stability later in life. Consistency in career choice over the life course may have positive outcomes down the line as career becomes part of an individual's identity. The current study uses the Life and Family Legacies dataset, a longitudinal state-representative sample of 3,348, to examine individual’s careers at three points in the life course: high school (projected career choice), early adulthood, and later life. Results revealed that a match of desired career in high school and actual career in early adulthood was not predictive of life satisfaction or depressive symptoms in later life. However, a match of career in early adulthood and later life was significantly related to better life satisfaction and less depressive symptoms, which was explained through higher levels of job satisfaction. This study highlights the importance of acquiring and maintaining a career that is fulfilling to the individual over the course of early adulthood to later life.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S706-S707
Author(s):  
Sarah Jen ◽  
Yuanjin Zhou ◽  
Mijin Jeong

Abstract In qualitative research, similarities and differences between the participant and researcher influence the research process and dynamics. Specifically, the age difference between older participants and relatively younger qualitative researchers is a common, but under-examined dynamic requiring nuanced, reflexive analysis. Using a life course conceptual framing, this study explored age-related participant-researcher dynamics in interviews from two qualitative studies of older women’s sexual experiences in later life. Participants included 25 women whose ages ranged from 55 to 93 and both studies were completed by the same researcher, a relatively younger woman (age 23 and 28 at times of data collection). A thematic analysis revealed three primary themes: 1) taking care - participants took care of the researcher by offering advice, asking about the researcher’s life, and expressing hopes for a positive future, 2) expertise – varied expertise was demonstrated by the researcher (e.g. substantive and scholarly) and participants (e.g. life experience), and 3) researcher growth - the researcher’s interviewing tactics shifted between the two studies (e.g. use of validation rather than consolation in response to aging-related concerns), indicating a shift in perceptions of aging and later life. Findings indicate that older women participants and younger women researchers are bound together through the life course, by shared gendered experiences, the fact that one will eventually become the other, and the mutual sharing of expertise and caring. Gerontology researchers must actively reflect on the impact of their own identities and aging perceptions on the interviewing process in order to enhance rigor in qualitative research.


2019 ◽  
pp. 34-49
Author(s):  
Kristin Litzelman

Although caregivers are often thought of as middle-aged or older adults, cancer caregiving spans the life course. This chapter discusses the unique challenges of cancer caregiving across the life course—early adulthood (18–44 years of age); middle age (45–64 years); and older age (adults 65 years and older)—using data from the 2015 Behavioral Risk Factor Surveillance System and evidence from the extant literature. More than 4 in 10 cancer caregivers were in early adulthood. Another 4 in 10 were in middle age, and nearly 2 in 10 were in older adulthood. Normative developmental patterns differ at each life stage, with implications for supporting cancer caregivers in clinical and policy settings. Future research embracing a nuanced view of caregiving across the life course and across relationship type will enhance the ability to care for caregivers and improve cancer survivor and caregiver well-being.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 580-581
Author(s):  
Roland Thorpe ◽  
Carl Hill

Abstract There is a paucity of research that seeks to understand why race disparities in health across the life course remain elusive. Two such explanations that have been garnering attention is stress and discrimination. This symposium contains papers seeking to address the impact of discrimination or stress on African American health or health disparities across the life course. First, Nguyen and colleagues examine 1) the associations between discrimination and objective and subjective social isolation and 2) how these associations vary by age in using data from the National Survey of American Life. Discrimination was positively associated with being subjectively isolated from friends only and family only. This relationship varied by age. Discrimination did not predict objective isolation. Second, Brown examines evidence of the black-white paradox in anxiety and depressive symptoms among older adults using data from 6,019 adults ages 52+ from the 2006 HRS. After adjusting for socioeconomic factors, everyday discrimination, chronic conditions, and chronic stress, there are no black-white differences in anxiety and depressive symptoms. Third, Cobb and colleagues investigate the joint consequences of multiple dimensions of perceived discrimination on mortality risk using mortality data from the 2006-2016 HRS. The authors report the number of attributed reasons for everyday discrimination is a particularly salient risk factor for mortality in later life. This collection of papers provides insights into how discrimination or stress impacts African American health or health disparities in middle to late life.


2019 ◽  
Vol 73 (9) ◽  
pp. 810-816 ◽  
Author(s):  
Margit Kriegbaum ◽  
Charlotte Ørsted Hougaard ◽  
Ingelise Andersen ◽  
Henrik Brønnum-Hansen ◽  
Rikke Lund

BackgroundSocial inequality in ischaemic heart disease has been related to socioeconomic position in childhood, early adulthood and late adulthood. However, the impact of relative level of accumulated income periods across adult life course and the potential gender and age differences have not been investigated. The aim was to investigate the association between relative level of accumulated income across the life course and acute myocardial infarction (AMI) from age 60+ years and to study if the associations differ by gender and in different age groups (30–39 years, 40–49 years and 50–59 years).MethodsAll Danes born 1935–1954 (N=1 235 139) were followed up in registers for incident AMI (42 669 cases). The accumulated proportional deviation from median equivalised income (APDMEI) for each gender/age/calendar year strata was constructed and divided in quartiles. The associations were analysed by means of Cox’s proportional hazard models.ResultsAmong men, those in the lowest APDMEI quartile had an HR 1.40 (1.35–1.45) of AMI compared with the highest quartile. Those in the second and third highest quartiles had HR of 1.24 (1.20–1.28) and 1.14 (1.10–1.18), respectively. Among women, the lowest quartile had an HR of 1.78 (1.69–1.88), the second 1.45 (1.37–1.53) and the third 1.19 (1.13–1.26). The social gradient was similar across the different age groups.ConclusionThe risk of AMI increased with lower levels of relative accumulated income across the life course. While men generally had a higher risk of AMI, the social gradient was steeper in women. There was no indication of a specific sensitive age period for exposure to relative level of accumulated income.


2020 ◽  
Author(s):  
Rachael A. Hughes ◽  
Kate Tilling ◽  
Deborah A. Lawlor

Longitudinal data are necessary to reveal changes within the same individual as they age. However, rarely will a single cohort capture data throughout the lifespan. We describe in detail the steps needed to develop life-course trajectories from cohorts that cover different and overlapping periods of life. Such independent studies are likely from heterogenous populations which raises several challenges including: data harmonisation (deriving new harmonised variables from differently measured variables by identifying common elements across all studies); systematically missing data (variables not measured are missing for all participants of a cohort); and model selection with differing age ranges and measurement schedules. We illustrate how to overcome these challenges using an example which examines the effects of parental education, sex, and ethnicity on weight trajectories. Data were from five prospective cohorts (Belarus and four UK regions), spanning from birth to early adulthood during differing calendar periods. Key strengths of our approach include modelling trajectories over wide age ranges, sharing of information across studies and direct comparison of the same parts of the life-course in different geographical regions and time periods. We also introduce a novel approach of imputing individual-level covariates of a multilevel model with a nonlinear growth trajectory and interactions.


Demography ◽  
2020 ◽  
Vol 57 (6) ◽  
pp. 1975-2001 ◽  
Author(s):  
Natalie Nitsche ◽  
Sarah R. Hayford

AbstractIn the United States, underachieving fertility desires is more common among women with higher levels of education and those who delay first marriage beyond their mid-20s. However, the relationship between these patterns, and particularly the degree to which marriage postponement explains lower fertility among the highly educated, is not well understood. We use data from the National Longitudinal Survey of Youth 1979 cohort to analyze differences in parenthood and achieved parity for men and women, focusing on the role of marriage timing in achieving fertility goals over the life course. We expand on previous research by distinguishing between entry into parenthood and average parity among parents as pathways to underachieving, by considering variation in the impact of marriage timing by education and by stage of the life course, and by comparing results for men and women. We find that women with a bachelor’s degree who desired three or more children are less likely to become mothers relative to women with the same desired family size who did not attend college. Conditional on becoming mothers, however, women with at least a bachelor’s degree do not have lower completed family size. No comparable fatherhood difference by desired family size is present. Postponing marriage beyond age 30 is associated with lower proportions of parenthood but not with lower parity among parents. Age patterns are similar for women and men, pointing at social rather than biological factors driving the underachievement of fertility goals.


2017 ◽  
Vol 48 (2) ◽  
pp. 205-225 ◽  
Author(s):  
Christopher R. Dennison

The consequences of “falling from grace”—or experiencing downward intergenerational mobility—are indeed becoming an abrupt reality for many entering the labor force. Scholars of social mobility speculate that such life course trajectories can result in antisocial behavior, but few have examined whether these trajectories lead to drug use. Thus, with the United States in the midst of a drug epidemic, as well as recovering from an economic recession, the study of social mobility may contribute to a better understanding of what causes individuals to turn to drugs. Using data from The National Longitudinal Study of Adolescent to Adult Health (Add Health) and a series of logistic diagonal reference models, this study examines the association between intergenerational social mobility and drug use. Overall, I find evidence that downward mobility is associated with increases in drug use, with the relationship strongest among those experiencing the greatest loss in status.


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