scholarly journals UNPACKING THE ETIOLOGY OF CHANGE IN BODY MASS INDEX AND WAIST-HIP RATIO IN MIDLIFE AND LATE LIFE USING SWEDISH TWIN DATA

2018 ◽  
Vol 2 (suppl_1) ◽  
pp. 619-620
Author(s):  
A K Dahl Aslan ◽  
C A Reynolds
2011 ◽  
Vol 30 (09) ◽  
pp. 707-712
Author(s):  
M. Simon ◽  
K. Mey ◽  
W. Hewer ◽  
T. Fett-Hamperl ◽  
L. Hermle

ZusammenfassungAnliegen: Zielkriterium der Studie ist die prospektive Gewichtsentwicklung hinsichtlich verschiedener Risikoparameter des metabolischen Syndroms bei Patienten mit bipolaren Spektrumserkrankungen unter Ersttherapie mit Valproat in Kombination mit definierten anderen Psychopharmaka. Patienten und Methode: Über die Dauer von neun Monaten wurde der Body-Mass-Index (BMI), Waist-Hip-Ratio (WHR), prozentuale Fettanteil und Leptinspiegel bei 14 Patienten untersucht. Ergebnisse: Es fand sich beim im Fettgewebe produzierten Leptin eine statistisch signifikante Korrelation mit dem BMI, WHR und dem prozentualen Fettanteils. Schlussfolgerungen: Die Ergebnisse weisen darauf hin, dass beiden 14 bipolaren Patienten unter Ersttherapie mit Valproat über die Dauer von neun Monaten kei-ne signifikante Gewichtszunahme feststellbar war. Es fand sich kein Zusammenhang zwischen der Valproatmedikation und den untersuchten Gewichtsparametern. Bei den Patienten lag bereits unter Baseline eine stammbetonte Adipositas mit erhöhtem BMI und WHR vor. Die vorliegende Untersuchung liefert Hinweise, dass bei Patienten mit langjähriger bipolarer Erkrankung eine erhöhte Prävalenz der mit dem metabolischen Syndrom assoziierten abdominellen Adipositas vorliegt. Weitere kon-trollierte Studien sind erforderlich, um die Ergebnisse zu bestätigen.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ida K. Karlsson ◽  
Margaret Gatz ◽  
Thalida Em Arpawong ◽  
Anna K. Dahl Aslan ◽  
Chandra A. Reynolds

AbstractBody mass index (BMI) is associated with cognitive abilities, but the nature of the relationship remains largely unexplored. We aimed to investigate the bidirectional relationship from midlife through late-life, while considering sex differences and genetic predisposition to higher BMI. We used data from 23,892 individuals of European ancestry from the Health and Retirement Study, with longitudinal data on BMI and three established cognitive indices: mental status, episodic memory, and their sum, called total cognition. To investigate the dynamic relationship between BMI and cognitive abilities, we applied dual change score models of change from age 50 through 89, with a breakpoint at age 65 or 70. Models were further stratified by sex and genetic predisposition to higher BMI using tertiles of a polygenic score for BMI (PGSBMI). We demonstrated bidirectional effects between BMI and all three cognitive indices, with higher BMI contributing to steeper decline in cognitive abilities in both midlife and late-life, and higher cognitive abilities contributing to less decline in BMI in late-life. The effects of BMI on change in cognitive abilities were more evident in men compared to women, and among those in the lowest tertile of the PGSBMI compared to those in the highest tertile, while the effects of cognition on BMI were similar across groups. In conclusion, these findings highlight a reciprocal relationship between BMI and cognitive abilities, indicating that the negative effects of a higher BMI persist from midlife through late-life, and that weight-loss in late-life may be driven by cognitive decline.


2019 ◽  
Vol 7 (4) ◽  
pp. 14
Author(s):  
Nuri Topsakal ◽  
Osman Ates ◽  
Burcak Keskin ◽  
Orhan Armutcu

The purpose of this study was to analyse the effects of combined aerobic and strength training in circuit training on body fat ratio. The universe of this study was selected as 32 male participants who continue their training and do fitness for health. Participants were divided into 2 groups: aerobic group (16 people) and combined group (16 people). This study was applied for 8 weeks, 3 days per week, and 1 hour per day. Participants were informed about how the tests will be conducted. An aerobic capacity test, body fat percentage, body mass index, and waist-hip ratio were among the applied tests and measurements. Data were analysed with SPSS 21 package program. Average and standard deviation of obtained data were calculated. Results showed that results of aerobic and combined trainings were similarly, and both aerobic and combined training positively affected body weight, body mass index, body fat percentage, and aerobic capacity values. Additionally, it can be stated that aerobic exercises directly affected waist-hip ratio compared to combined exercises, and combined training was more efficient for waist-hip ratio.


2011 ◽  
Vol 140 (5) ◽  
pp. S-249
Author(s):  
Nasser Hajar ◽  
Sonia Brar ◽  
Nazif Chowdhury ◽  
Shahid Ali ◽  
Richard Rackett ◽  
...  

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