scholarly journals COGNITION OLDER ADULTS WITH PREDIABETES EXPERIENCE ACCELERATED NEUROCOGNITIVE DECLINE

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S654-S655
Author(s):  
Joyla Furlano ◽  
Lindsay Nagamatsu
Keyword(s):  
Older Adults ◽  
Hippocampal Volume ◽  
Brain Health ◽  
Cross Sectional ◽  
Cognitive Domains ◽  
Functional Brain ◽  
Cross Sectional Analysis ◽  
Brain Changes ◽  
Sectional Analysis ◽  
Neurocognitive Decline

Abstract Type II diabetes (T2D) is associated with neurocognitive decline beyond normative aging, and thus older adults with T2D are at high risk for developing dementia. However, the extent to which similar deficits occur in prediabetic older adults is not well understood. While few studies have shown that prediabetic older adults experience some cognitive decline, further research is needed to determine the specific cognitive domains affected and the degree to which this decline occurs. Moreover, structural and functional brain changes that may occur with these deficits is currently unknown in this population. Therefore, the aim of this study was to assess cognitive function and brain health in prediabetic older adults. We conducted a cross-sectional analysis of older adults (aged 60-80) with prediabetes (FPG 6.1-7.0 mmol/L) and healthy aged-matched controls, examining 1) cognitive performance, 2) functional brain activation as measured by fMRI, and 3) structural measures such as volume of the hippocampus. Based on our cross-sectional analysis, prediabetic older adults show impaired cognition (e.g., memory), as well as decreased hippocampal volume and activation. Therefore, we conclude that older adults with prediabetes experience brain decline, and could benefit from lifestyle interventions to prevent or delay the onset of such decline.

scholarly journals Caregiver Status and Diet Quality in Community Dwelling Older Adults

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 205-205
Author(s):  
Sharmin Hossain ◽  
May A Beydoun ◽  
Michele K Evans ◽  
Alan B Zonderman ◽  
Marie Fanelli Kuczmarski
Keyword(s):  
Older Adults ◽  
Diet Quality ◽  
Research Program ◽  
Healthy Eating Index ◽  
Longitudinal Analyses ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Intramural Research Program ◽  
Sectional Analysis ◽  
Over Time

Abstract Objectives Prior studies on caregivers have focused mainly on the diet quality of their recipients, especially children. We investigated both cross-sectional and longitudinal associations of caregiver status and diet quality in older adults (mean 53.0 ± 9.0 years). Methods We studied participants in the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study (57.7% women, 62% African American) between wave 3 (2009–2013) and wave 4 (2013–2018). Caregiving was assessed at both waves, starting at wave 3. Healthy Eating Index-2010 (HEI2010) score, a measure of diet quality, was assessed from two 24-hour recalls at each wave on both occasions (mean 4.1 years follow-up). Baseline caregiving (at wave 3) was examined in relation to change in HEI between waves 3 and 4. Multivariable linear regression was performed for cross-sectional analysis; mixed-effects regression was performed for longitudinal analyses. Results are expressed as β-coefficients ± standard error of means (β±SE). Results After adjusting for age, sex, race and poverty status, more time spent taking care of grandchildren (N = 2033) was associated with poor diet quality (–1.51 ± 0.55, P = 0.006) in cross-sectional analysis (wave 4 caregiving and wave 4 HEI). However, in a separate cross-sectional analysis (wave 4 only) on dual (caring for both grandchildren and an elderly person) vs. single caregivers (either grandchildren or elderly) (N = 73; 24 men & 49 women) we found no difference in diet quality. The longitudinal analyses (N = 1848) demonstrated that diet quality did not change with caregiving over time for either grandchildren (P = 0.16) or others (not children & grandchildren) (P = 0.88). Overall, women tended to have better quality diet (P < 0.001) than men. Conclusions Among relatively older caregivers, cross-sectional analyses revealed an inverse effect of caregiving with diet quality. Longitudinal research is needed to evaluate the temporal associations of dual caregiving with subsequent diet quality changes over time. Funding Sources The first author is supported by a Postdoctoral Fellowship from the Intramural Research Program (IRP) at the National Institute on Aging (NIA). HANDLS is supported by the Intramural Research Program, National Institute on Aging, National Institutes of Health, grant Z01-AG000513.

Disparities in pneumococcal and influenza immunization among older adults in Israel: A cross-sectional analysis of socio-demographic barriers to vaccination

2013 ◽  
Vol 56 (5) ◽  
pp. 337-340 ◽  
Author(s):  
Andrea Wershof Schwartz ◽  
A. Mark Clarfield ◽  
John T. Doucette ◽  
Liora Valinsky ◽  
Tomas Karpati ◽  
...  
Keyword(s):  
Older Adults ◽  
Cross Sectional ◽  
Influenza Immunization ◽  
Cross Sectional Analysis ◽  
Sectional Analysis
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