scholarly journals Modern History of Cholera Vaccines and the Pivotal Role of icddr,b

Author(s):  
Jan Holmgren

Abstract The rapid spread of the 7 th cholera pandemic over Asia in the 1960s led to several large field studies that revealed that the traditional injectable cholera vaccines had poor efficacy, usually less than 50% for only 3-6 months, which led WHO in the 1970s to stop recommending cholera vaccination. At the same time, it stimulated research that has led to the development of the effective orally administered cholera vaccines (OCVs) that today are a cornerstone in WHO´s strategy for “Ending Cholera – A Global Roadmap to 2030”. The first effective OCV, Dukoral™, containing a mixture of inactivated Vibrio cholerae bacteria and cholera toxin B subunit, was licenced in 1993 and is together with two similar inactivated whole-cell OCVs, Shanchol™ and Euvichol™/Euvichol-Plus™, the OCVs currently prequalified and recommended by WHO. This brief review is a personalized account of the “modern history” of the development of these now universally recognized effective tools for the control and ultimate elimination of cholera, and of the pivotal role of icddr,b and Bangladesh for this development.

Tornado God ◽  
2020 ◽  
pp. 11-35
Author(s):  
Peter J. Thuesen

Chapter 1 interweaves the story of the 1974 Xenia, Ohio, tornado (part of the infamous Super Outbreak) with background on the pivotal role of weather in the premodern and early modern history of religions. The storm god tradition, exemplified by the biblical Yahweh and other deities from across the world’s cultures, laid the conceptual foundation for later American interpretations of the weather. Medieval and early modern theologians drew on elements of this tradition in devising their more rationalistic doctrines of providence, but in so doing they bequeathed to later generations a tangle of logical difficulties. Among these was the question of what role, if any, chance played in the weather. To John Calvin, “chance” was a pagan notion, but excluding chance exacerbated the problem of theodicy, or why a benevolent God allowed deadly storms and other natural evils.


1989 ◽  
Vol 17 (2) ◽  
pp. 159-175
Author(s):  
Thomas Russell

Too much of the history of missions has been written about the men who went to the field. Studies of Victorian missions have followed this course. While women played a pivotal role in the Protestant missionary enterprise of the late nineteenth century, their story has often been neglected. This essay analyzes the role of women in the Student Volunteer Movement and challenges historians and missiologists alike to reexamine the SVM saga in light of the contributions of women.


Author(s):  
Timur Gimadeev

The article deals with the history of celebrating the Liberation Day in Czechoslovakia organised by the state. Various aspects of the history of the holiday have been considered with the extensive use of audiovisual documents (materials from Czechoslovak newsreels and TV archives), which allowed for a detailed analysis of the propaganda representation of the holiday. As a result, it has been possible to identify the main stages of the historical evolution of the celebrations of Liberation Day, to discover the close interdependence between these stages and the country’s political development. The establishment of the holiday itself — its concept and the military parade as the main ritual — took place in the first post-war years, simultaneously with the consolidation of the Communist regime in Czechoslovakia. Later, until the end of the 1960s, the celebrations gradually evolved along the political regime, acquiring new ritual forms (ceremonial meetings, and “guards of memory”). In 1968, at the same time as there was an attempt to rethink the entire socialist regime and the historical experience connected with it, an attempt was made to reconstruct Liberation Day. However, political “normalisation” led to the normalisation of the celebration itself, which played an important role in legitimising the Soviet presence in the country. At this stage, the role of ceremonial meetings and “guards of memory” increased, while inventions released in time for 9 May appeared and “May TV” was specially produced. The fall of the Communist regime in 1989 led to the fall of the concept of Liberation Day on 9 May, resulting in changes of the title, date and paradigm of the holiday, which became Victory Day and has been since celebrated on 8 May.


2004 ◽  
Vol 23 (2) ◽  
pp. 31-38 ◽  
Author(s):  
Elizabeth Reedy

Nearly 50 years after it was thought to be conquered, retinopathy of prematurity (ROP) continues to cause vision disturbances and blindness among prematurely born infants. During the 1940s and early 1950s, researchers and caregivers first identified and struggled to eliminate this problem, which seemed to come from nowhere and was concentrated among the most advanced premature nurseries in the U.S. Research studies initially identified many potential causes, none of which could be proved conclusively. By the mid-1950s, oxygen was identified as the culprit, and its use was immediately restricted. The rate of blindness among premature infants decreased significantly. ROP was not cured, however. By the 1960s, it had reappeared. The history of ROP serves to remind us that, despite our best intentions, the care and treatment of premature newborns will always carry with it the possibility of iatrogenic disease. This caution is worth remembering as we work to expand the quality and quantity of clinical research.


Author(s):  
Andrea Giardina

Marxism has slowly declined in recent literature on the economic and social history of the ancient world. If one happens to run into the name of Marx or the term Marxism, it is generally within the context of polemical remark. In spite of recurrent attempts to resuscitate it as an ideal foil for anti-Communist polemic, Marxism made its final exit from the field of ancient historical studies in the 1960s, when new Marxist and Marxist-inspired historiography came to the fore. This chapter discusses the changing role of Marxism in Italian history-writing. It focuses on the historians who claim themselves as Marxists, and those who employ Marxist categories and draw on Marxist theory yet refuse to be defined as Marxists. The chapter examines the debates of the different groups on the historiographic phase marked by the circulation of Marxist concepts, analytical tools, and models outside the strictly Marxist milieu. One of the most striking aspects of this phase is the existence of a trend for the formation of research groups that shared not only an affinity or ideological adherence to Marxism, but also an interest in historical theory and a similar orientation in cultural politics. These interdisciplinary approaches stimulated the confluence of individual competences in group projects aimed at singling out new topics and developing investigational strategies. This historiographic phase also reflected a sense of community, a refusal of traditional academic hierarchies, a wish to keep individualism in check, and the rejection of erudite isolation. In Italy, these forms of association served as a means for ethical and political self-representation of cultural hegemony.


This chapter extends the book’s insights about nature, technology, and nation to the larger history of the modern period. While the modern nation loses its grip as a locus of identity and analysis, attempts to understand the operation, disruption, and collapse of continental and global infrastructures continue to mix the natural and the machinic in ways that define them both. Those vulnerabilities emphasize large-scale catastrophe; historiographically, they mask the crucial role of small-scale failures in the experience and culture of late modernity, including its definition of nature. Historical actors turned the uneven geographical distribution of small-scale failures into a marker of distinctive local natures and an element of regional and national identity. Attending to those failures helps not only situate cold-war technologies in the larger modern history of natural and machinic orders; it helps provincialize the superpowers by casting problematic “other” natures as central and primary.


Author(s):  
Monique A. Bedasse

This chapter sets the pan-African context in which the repatriation occurs. In particular, it explains the rise of Tanzania as a safe haven for African freedom fighters and radical diasporic Africans in the 1960s and 1970s, connecting the repatriation to wider diasporic engagement with Tanzania in this period. It places ujamaa within the context of other African socialisms of the day and highlights the role of pan-Africanism in the making of Tanzania’s modern history.


2019 ◽  
pp. 61-87
Author(s):  
Kate Bedford

Using legislation, case law, and official records (including Hansard), Chapter 2 outlines the early history of state intervention into bingo in England and Wales. The chapter traces the gradual liberalization of restrictions on small-scale gambling, and the subsequent backlash against bingo in the 1960s. It also tells a new story about gambling regulation and political economy. In particular, it excavates the key role of mutual aid to elite debates about the proper place of gambling in national life. Although many authors have argued that disavowal of gambling helped legitimize the forms of collective insurance developed by early friendly societies and similar associations, the chapter shows that gambling played a key role—as entertainment and mutual aid—within working men’s clubs, and that it was promoted by the state. This mutual aid dimension of gambling was heavily conflicted in gendered terms. Lawmakers were lobbied by bingo-organizing men, with women’s interests at least one step removed from Hansard. Unequal gender roles were hereby woven into dominant understandings of small-scale gambling.


Author(s):  
Eugene Judson ◽  
Daiyo Sawada

Surprising to many is the knowledge that audience response systems have been in use since the 1960s. Reviewing the history of their use from the early hardwired systems to today’s computer-integrated systems provides the necessary scope to reflect on how they can best be used. Research shows that the systems have had consistent effects on motivation, and varying effects on student achievement over the years. The intent of this chapter is to consider lessons learned, consider the relation of technology and pedagogy, and to highlight elements of effective use. This chapter emphasizes the crucial role of pedagogy in determining whether audience response systems can lead to greater student achievement.


2019 ◽  
Vol 16 (1) ◽  
pp. 141-155
Author(s):  
SIMON FRITH

AbstractThis article considers the role of Marxism in the history of popular music studies. Its approach combines the sociology of knowledge with a personal memoir and its argument is that in becoming a field of scholarly interest popular music studies drew from both Marxist theoretical arguments about cultural ideology in the 1950s and 1960s and from rock writers’ arguments about the role of music in shaping socialist bohemianism in the 1960s and 1970s. To take popular music seriously academically meant taking it seriously politically. Once established as an academic subject, however, popular music studies were absorbed into both established music departments and vocational, commercial music courses. Marxist ideas and ideologues were largely irrelevant to the subsequent development of popular music studies as a scholarly field.


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