scholarly journals Chymase Level Is a Predictive Biomarker of Dengue Hemorrhagic Fever in Pediatric and Adult Patients

2017 ◽  
Vol 216 (9) ◽  
pp. 1112-1121 ◽  
Author(s):  
Hasitha Tissera ◽  
Abhay P S Rathore ◽  
Wei Yee Leong ◽  
Brian L Pike ◽  
Tyler E Warkentien ◽  
...  
Keyword(s):  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever ◽  
Predictive Biomarker ◽  
Adult Patients

scholarly journals CLINICAL CHARACTERISTIC OF ADULT PATIENTS WITH DENGUE HEMORRHAGIC FEVER AT PROF. DR. SULIANTI SAROSO SUNTER INFECTIOUS HOSPITAL 2018

2020 ◽  
Vol 1 (1) ◽  
pp. 26
Author(s):  
Ghina Rasyidah ◽  
Adinta Anandani
Keyword(s):  
Dengue Hemorrhagic Fever ◽  
Clinical Manifestations ◽  
Hemorrhagic Fever ◽  
Viral Disease ◽  
Adult Patients ◽  
H2 Antagonist ◽  
Average Patient ◽  
Serology Test ◽  
Age Range ◽  
Clinical Characteristic

Background: Dengue is a viral disease transmitted by mosquito to humans and becomes a problem for the health of Indonesian people. Dengue Hemorrhagic Fever occurs due to several epidemiological factors. The purpose of this study is to determine the clinical characteristics of adult patients with Dengue Hemorrhagic Fever at Prof. dr. Sulianti Saroso Sunter Infectious Hospital 2018. Method: This Study was an observational descriptive study by taking medical record samples in 49 adult patients Dengue Hemorrhagic Fever in 2018. Results: From the 49 cases of Dengue Haemorrhagic Fever, the highest fender category was male (65,3%), occurred in the 18-25 year age category (38,8%), and the average patient worked as a Private Employee (55,1%). Most patients were hospitalized for the less than 7 days (83,7%). Clinical manifestations were fever (95,9%), nausea (85,7%) and headache (71,4%). Physical examination found was fever (100%) and hepatomegaly (12,2%). Laboratory tests showed normal hematocrit values (71,4%), thrombocytopenia values (87,8%), normal leukocyte values (49%), positive IgG serology tests (83,7%), IgM serology tests (71,4%), Positive IgM and IgG Serology test (69,3%), and NS1 Serology test (2%). Management provided is the administration of intravenous infus fluid drops (100%), PPI (87,8%), H2 Antagonist (4,1%), and Antipiretik (83,7%). The outcome patient is recovered and no complications were found. Conclusion: Dengue Hemorrhagic fever occurs in the age range of 18-25 years with dominant clinical characteristic of fever and thrombocytopenia. And, the most given treatment is Intravena Fluid therapy. 

scholarly journals PLASMA LEAKAGE PROFILES OF DENGUE HEMORRHAGIC FEVER PATIENTS IN RSUD Dr. SOETOMO, SURABAYA, EAST JAVA, INDONESIA JANUARY – JUNE 2014

2017 ◽  
Vol 6 (4) ◽  
pp. 92
Author(s):  
Ferdian Rizaliansyah ◽  
Aryati Aryati ◽  
Musofa Rusli
Keyword(s):  
Pleural Effusion ◽  
Dengue Hemorrhagic Fever ◽  
Pediatric Patients ◽  
Hemorrhagic Fever ◽  
Healthcare Services ◽  
Albumin Level ◽  
Adult Patients ◽  
Dengue Virus Infection ◽  
Plasma Leakage ◽  
Normal Albumin

Plasma leakage is one crucial point of dengue hemorrhagic fever (DHF) that differentiates it from dengue fever (DF). DHF has to meet 4 criteria which are 2 – 7 days of acute fever, hemorrhagic manifestation, thrombocytopenia (≤100.000 cells/mm3) and evidence of plasma leakage. Plasma leakage consists of increasing hematocrit ≥20%, hypoalbuminemia or evidence of pleural effusion or ascites. Often doctors only base their DHF diagnosis on the presence of thrombocytopenia. This study analyzed the presence of plasma leakage between adult and pediatric patients with a DHF diagnosis in RSUD Dr. Soetomo in order to make the diagnosis and healthcare services better in the future. This was a retrospective study which used medical records of DHF patients admitted from January to June 2014. 78 cases were included, 24 adult patients (31%) and 54 pediatric patients (69%). 29/78 (37%) patients had no evidence of plasma leakage. No adult patients had ascites whereas 11/54 (20%) pediatric patients presented with ascites. No adult patients had pleural effusion whereas 25/54 (53%) pediatric patients did. Most adult patients that had serum albumin checked had normal albumin levels (12/14 [86%]) while only 14/28 (52%) pediatric patients had normal albumin level. 5/22 (23%) adult patients versus 32/53 (60%) pediatric patients showed hematocrit increments ≥20%. Patients admitted with dengue virus infection may currently be often misclassified as DHF because there are no plasma leakage manifestation in some patients.. There are significant differences in plasma leakage manifestations between adult and pediatric patients which poses a theory that pediatric patients are more susceptible to have plasma leakage manifestations than adult patients.

scholarly journals CORRELATION OF DENGUE VIRUS SEROTYPE AND DVI SEVERITY IN ADULT PATIENTS

2018 ◽  
Vol 24 (2) ◽  
pp. 185
Author(s):  
Suci Andriani ◽  
Aryati Aryati ◽  
Usman Hadi
Keyword(s):  
Virus Infection ◽  
Dengue Virus ◽  
Real Time ◽  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever ◽  
Adult Patients ◽  
Rt Pcr ◽  
Dengue Virus Infection ◽  
Virus Serotype ◽  
Degree Of Severity

The clinical manifestation of dengue virus infection is often not clear, varies widely from mild to severe. Exposure of dengue virus which serotype is different from a previous infection is a risk factor for the severe manifestation of dengue virus infection. Dengue hemorrhagic fever is classified into four degrees of severity based on clinical manifestations and laboratory results. Real-time RT-PCR Dengue can detect dengue virus serotype in early dengue virus infection. The aimed of this study was to prove the correlation between dengue virus serotype and degree of severity in adult patients. This study was a cross-sectional observational design done in February until July 2016. Subjects consisted of 100 dengue virus infection patients. Serum of the patients was examined using Real-time RT-PCR Dengue (Simplexa™ Dengue). It was shown that from 46 patients with DENV-3 serotype was 63%, DENV-2 serotype 17.4%, DENV-1 serotypes 17.4% and mixed infection of DENV-1 and DENV-3 serotype 2.2%. There was not any DENV-4 serotype. Dengue Hemorrhagic Fever (DHF) stage I was 47.8%, DHF stage II was 30.4%, DHF stage III was 10.9% and Dengue Fever was 10.9%. There was not any DHF stage IV. There was not enough evidence that DENV-3 correlated with the degree of severity (p= 0.510). Based on this research, DENV-3 serotype was the dominant serotype prevalent at the Dr. Soetomo Hospital. There was no correlation between viral dengue serotype and severity in dengue adult patients in this study. 

PENGARUH PELATIHAN PENGENDALIAN VEKTOR DEMAM BERDARAH TERHADAP MAYA INDEX PADA SISWA SEKOLAH DASAR DI MAJALENGKA

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Wawan Kurniawan
Keyword(s):  
Vector Control ◽  
Dengue Fever ◽  
Dengue Hemorrhagic Fever ◽  
Intervention Group ◽  
Hemorrhagic Fever ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Quasi Experimental ◽  
Dengue Vector Control

ABSTRAK  Latar belakang: Demam Berdarah Dengue (DBD) disebabkan oleh virus Dengue dapat menyebabkan kematian. Pencegahan DBD yang dianggap paling tepat adalah Pemberantasan Sarang Nyamuk (PSN). Penelitian ini bertujuan untuk mengetahui pengaruh pelatihan pengendalian vektor Demam Berdarah pada siswa sekolah dasar terhadap Maya Index di Majalengka. Metode: Penelitian ini menggunakan desain quasi experiment (pretest-posttest control group design). Sebanyak 4 sekolah terpilih sebagai kelompok intervensi dan 4 sekolah lainnya sebagai kontrol. Subyek penelitian adalah siswa kelas IV-VI yang terdiri dari 171 siswa pada kelompok intervensi dan 163 pada kelompok kontrol. Instrumen yang digunakan adalah formulir pemantauan jentik berkala. Hasil: Jumlah rumah dengan kategori Maya Index tinggi berkurang dari 27,5% menjadi 9,4%. Terjadi penurunan angka BRI kategori tinggi pada kelompok intervensi dari 20,5% menjadi 1,8%. Pada kelompok kontrol tidak terjadi penurunan angka BRI kategori tinggi (22,1%), sebaliknya terjadi penurunan kategori rendah dari 34,4% menjadi 3,7%. Tidak terjadi penurunan angka HRI pada kelompok intervensi maupun kontrol. Kesimpulan: Pelatihan pengendalian vektor Demam Berdarah dapat menurunkan nilai BRI dan Maya Index, tetapi tidak berpengaruh terhadap nilai HRI. Tidak adanya perubahan nilai HRI menunjukkan bahwa kebersihan dan sanitasi lingkungan merupakan faktor yang berpengaruh terhadap probabilitas kejadian demam berdarah. Kata Kunci : Demam Berdarah, Maya Index, pelatihan, pengendalian vektor   ABSTRACT Background: Dengue Hemorrhagic Fever (DHF) caused by Dengue virus could cause death. The most appropriate prevention of Dengue is eradication of mosquito nests (PSN). This study aims to determine the effect of Dengue vector control training on elementary students towards Maya Index in Majalengka. Method: This study used quasi-experimental design (pretest-posttest control group design). A total of 4 schools were selected as intervention groups and 4 other schools as controls. The subjects were students in grades IV-VI consisting of 171 students in the intervention group and 163 in the control group. The instrument used was periodic larva monitoring form. Results: The number of houses with a high Maya Index category in the intervention group decreased from 27.5% to 9.4%. There was a decrease in the high BRI category in the intervention group from 20.5% to 1.8%. In the control group, there was no decrease in the high BRI category (22.1%), on the contrary, there was a decrease in the low category from 34.4% to 3.7%. There was no decrease in HRI rates both of intervention or control groups. Conclusion: Dengue Fever vector control training could decrease the value of BRI and Maya Index, but does not affect the value of HRI. The absence of changes in HRI  indicate that environmental hygiene and sanitation are factors that influence the probability of dengue fever occurrence. Keywords: Dengue Hemorrhagic Fever, Maya Index, training, vector control

SISTEM PAKAR MENDIAGNOSA VIRUS MAYORA DENGAN METODE VARIABLE CENTERED INTELLIGENT RULE SYSTEM (VCIRS)

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Siti Nurhena ◽  
Nelly Astuti Hasibuan ◽  
Kurnia Ulfa
Keyword(s):  
Artificial Intelligence ◽  
Immune System ◽  
Expert System ◽  
Expert Systems ◽  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever ◽  
Visual Basic ◽  
Artificial Intelligence Techniques ◽  
Individual Needs ◽  
Rule System

The diagnosis process is the first step to knowing a type of disease. This type of disease caused by mosquitoes is one of the major viruses (MAVY), dengue hemorrhagic fever (DHF) and malaria. Sometimes not everyone can find the virus that is carried by this mosquito, usually children who are susceptible to this virus because the immune system that has not been built perfectly is perfect. To know for sure which virus is infected by mosquitoes, it can diagnose by seeing symptoms perceived symptoms. Expert systems are one of the most used artificial intelligence techniques today because expert systems can act as consultations. In this case the authors make a system to start a diagnosis process with variable centered intelligent rule system (VCIRS) methods through perceived symptoms. With the facilities provided for users and administrators, allowing both users and administrators to use this system according to their individual needs. This expert system is made with the Microsoft Visual Basic 2008 programming language.Keywords: Expert System, Mayora Virus, Variable Centered Intelligent Rule System (VCIRS)The diagnosis process is the first step to knowing a type of disease. This type of disease caused by mosquitoes is one of the major viruses (MAVY), dengue hemorrhagic fever (DHF) and malaria. Sometimes not everyone can find the virus that is carried by this mosquito, usually children who are susceptible to this virus because the immune system that has not been built perfectly is perfect. To know for sure which virus is infected by mosquitoes, it can diagnose by seeing symptoms perceived symptoms.Expert systems are one of the most used artificial intelligence techniques today because expert systems can act as consultations. In this case the authors make a system to start a diagnosis process with variable centered intelligent rule system (VCIRS) methods through perceived symptoms.With the facilities provided for users and administrators, allowing both users and administrators to use this system according to their individual needs. This expert system is made with the Microsoft Visual Basic 2008 programming language.Keywords: Expert System, Mayora Virus, Variable Centered Intelligent Rule System (VCIRS)

Difusi dan Pola Spasial Sebaran Penyakit Demam Berdarah Dengue (DBD) Di Kota Bandar Lampung

2018 ◽  
Vol 1 (1) ◽  
pp. 87-95
Author(s):  
Nurul Qamila ◽  
Agel Vidian Krama
Keyword(s):  
Public Health ◽  
Spatial Analysis ◽  
Aedes Aegypti ◽  
Dengue Virus ◽  
Spatial Pattern ◽  
Dengue Hemorrhagic Fever ◽  
Health Problem ◽  
Public Health Problem ◽  
Hemorrhagic Fever ◽  
Descriptive Method

Dengue hemorrhagic fever (DHF) is a contagious disease caused by the dengue virus and is transmitted by the mosquito Aedes aegypti (Aa.aegypti). The population is still a public health problem that increases the number of sufferers and also widespread, with population and education. This study aims to reveal the spatial pattern and distribution of Dengue Hemorrhagic Fever (DHF) with the spatial pattern and the spread of Dengue Hemorrhagic Fever (DHF) can result in different locations of these allegations. From the map that can be used for the prevention of Dengue Hemorrhagic Fever (DBD) in Bandar Lampung City. This study aims to reveal the spatial pattern and distribution of Dengue Hemorrhagic Fever (DHF) with the descriptive method and spatial pattern of Dengue Hemorrhagic Fever (DHF) can result in different locations of these allegations. From the map that can be used for the prevention of Dengue Hemorrhagic Fever (DBD) in Bandar Lampung City. Keywords: DHF, Spatial Analysis

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