scholarly journals Adverse effects on growth performance and bone development in nursery pigs fed diets marginally deficient in phosphorus with increasing calcium to available phosphorus ratios

2020 ◽  
Vol 98 (10) ◽  
Author(s):  
Spenser L Becker ◽  
Stacie A Gould ◽  
Amy L Petry ◽  
Leah M Kellesvig ◽  
John F Patience

Abstract The objective of this experiment was to evaluate the growth performance and bone mineral content (BMC) of nursery pigs in response to increasing total calcium (Ca) to available phosphorus (aP) ratios in diets containing phytase (250 FTU/kg; Natuphos E, BASF, Florham Park, NJ). A total of 480 nursery pigs (body weight (BW) = 5.7 ± 0.6 kg) with 10 pigs per pen and 7 pens per treatment (6 pens fed 2.75:1 diet) were allotted to seven treatments consisting of increasing ratios of calcium to available phosphorus (Ca:aP): 1.25, 1.50, 1.75, 2.00, 2.25, 2.50, and 2.75. From day −7 to 0, pigs were fed a common diet. They were then fed the treatment diets during two experimental phases from day 1 to 14 and 15 to 28, respectively. Available P was formulated to 0.33% and 0.27% (approximately 90% of requirement) in dietary phases 1 and 2, respectively. BW, average daily gain (ADG), average daily feed intake (ADFI), and gain-to-feed ratio (G:F) were determined. BMC of the femur was measured on day 28 on one pig per pen using dual x-ray absorptiometry. Data were analyzed as a linear mixed model using PROC MIXED (SAS, 9.3). Orthogonal polynomial contrasts were used to determine the linear and quadratic effects of increasing the Ca:aP. Over the 28-d experimental period, increasing Ca:aP resulted in a linear decrease in ADG (353, 338, 328, 304, 317, 291, and 280 g/d; P < 0.01), ADFI (539, 528, 528, 500, 533, 512, and 489 g/d; P < 0.05), and G:F (0.68, 0.66, 0.64, 0.62, 0.61, 0.59, and 0.58; P < 0.01). Increasing Ca:aP also resulted in decreased BW on days 14 and 28 (P < 0.01). The BMC of the femur decreased with increasing Ca:aP (6.2, 6.3, 5.7, 5.9, 5.5, 5.6, and 5.3 g; P < 0.05). Regression analysis explained the impact of Ca:aP as follows on ADG (ADG [g/d] = 339 − 36x; r2 = 0.81), G:F (G:F = 0.61 – 0.03x; r2 = 0.72), and BMC (BMC [g] = 6.4 – 0.27x; r2 = 0.43), where x is the Ca:aP. In conclusion, all outcomes indicated that any level of calcium above the minimum used in this experiment impaired growth performance and skeletal development. Further research using even lower levels of dietary Ca is warranted.

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 93-93
Author(s):  
Sara Ebarb ◽  
Sabrina May ◽  
Mark D Newcomb

Abstract Fiber ingredients in swine diets have various components that affect the intestinal tract distinctively. The objective of this study was to determine the effect of structural fiber sources on growth performance of nursery pigs. A total of 1,760 weanling pigs (initial BW = 6.12 ± 0.3 kg, 16 reps/trt, 22 pigs/pen) were used in a study with 5 dietary treatments: 1) Complex nursery diet with no additional fiber (CON); 2) CON + 2% rice hulls; 3) CON + 4% rice hulls; 4) CON + 6% wheat middlings; 5) CON + 12% wheat middlings. Fiber ingredients were added at the expense of corn and some processed soybean meal to maintain similar dietary protein levels. Using an in vitro fermentation estimation of fermentation for rice hulls and wheat middlings, diets were constructed to add similar levels of structural (non-fermentable NDF) fiber between low and high additions of rice hulls and wheat middlings. Pens across two barns were randomly allotted independent of one another and within a location block to one of the five treatments on d 0 of a two-phase study (d 0–11 and d 11–20.5 post-weaning). Data were analyzed by general linear model in R. Mortality and removal data were analyzed as a generalized linear mixed model with a binomial distribution. Contrasts tested the effect of additional fiber (CON vs treatments 2–5), effect of medium vs high fiber (treatment 2/4 vs 3/5), effect of source of fiber (treatment 2/3 vs 4/5), and the interaction of level and source of fiber. Overall (Table 1), additional fiber resulted in increased ADFI (P < 0.05) and tended to increase ADG (P < 0.10). Probability of mortality and removal was reduced (P < 0.05) when additional fiber was included. In summary, increasing the level of structural fiber improved performance and livability of nursery pigs.


2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 75-76
Author(s):  
Mariana Boscato Menegat ◽  
Michaela B Braun ◽  
Joel M DeRouchey ◽  
Jason C Woodworth ◽  
Jim Bryte ◽  
...  

Abstract This study evaluated the progeny of sows fed a control or probiotic diet with Bacillus subtilis C-3102 (Calsporin®, Calpis Co. Ltd., Tokyo, Japan) at 500,000 and 1,000,000 CFU/g diet in gestation and lactation, respectively. A total of 358 weaned pigs (DNA 241 × 600) were used in a 42-d trial with 4–5 pigs/pen and 18–19 pens/treatment. Pens were allotted to treatments in a completely randomized design based on BW at weaning. Treatments were a 2×2 factorial with main effects of sow diet (control vs. probiotic) and nursery diet (control vs. probiotic). In the nursery probiotic diet, a product based on probiotic Bacillus subtilis C-3102 at 500,000 CFU/g diet and prebiotics β-glucans and mannan oligosaccharides was included at 0.05% (BacPack ABF™, Quality Technology International, Inc., Elgin, IL). Diets were corn-soybean meal-based. Growth performance and fecal consistency on a 1-to-5 scale were evaluated weekly. Fecal samples were collected for microbial analysis by culture method and bacterial quantification of Bacillus subtilis C-3102, total Bacillus sp., Lactobacillus sp., Clostridium perfringens, Salmonella spp., Enterococcus sp., Enterobacteriaceae, total aerobes, and total anaerobes. Data were analyzed using a linear mixed model (PROC GLIMMIX, SAS®) with pen as experimental unit. There was no evidence for effect of sow diet, nursery diet, or interactions (P > 0.10) on overall nursery growth performance and fecal consistency. However, growth performance from d 21 to 42 and final BW were greater (P < 0.05) in progeny of control-fed sows compared to probiotic-fed sows. Microbial analysis revealed an increase (P < 0.01) in Bacillus subtilis C-3102 and, consequently, total Bacillus sp. in fecal microflora of probiotic-fed pigs. In conclusion, probiotic inclusion to sow diets lowered growth performance of the progeny in late nursery. The probiotic diet provided to sows or nursery pigs did not influence fecal consistency, but altered the fecal microbial population in nursery pigs by increasing total Bacillus sp.


Author(s):  
Ashton D Yoder ◽  
Charles R Stark ◽  
Joel M DeRouchey ◽  
Michael D Tokach ◽  
Chad B Paulk ◽  
...  

Abstract Mycotoxins are naturally-produced hazards that result from molds grown on cereal grains and other commodities. These molds may produce carcinogenic mycotoxins, which can be harmful to humans and animals. Removing broken kernels has been demonstrated to reduce mycotoxin concentration, but with high variability. Therefore, two experiments were conducted to quantify the magnitude of natural mycotoxin concentration that may be reduced by cleaning corn. Two loads of corn that were naturally contaminated with mycotoxins were procured. Corn for Experiment 1 was contaminated with aflatoxin (1,074 parts per billion; ppb), fumonisin (8.3 parts per million; ppm), and ochratoxin A (206 ppb), while corn for Experiment 2 was contaminated with only fumonisin (5.5 ppm). Corn was cleaned by mechanical sieving. For each experiment, corn was divided into twenty 150 kg runs. Runs were randomly assigned to 1 of 4 experimental treatments: 1) no screen 2) 12.7 mm screen, 3) 4.8 mm screen, and 4) 12.7 + 4.8-mm screen. The corn cleaner was sanitized between runs. Three 5 kg corn samples were collected from each run, and analyzed for mycotoxin concentration. In Experiment 1, cleaning reduced (P &lt; 0.05) aflatoxin and fumonisin concentration by an average of 26% and 45%, respectively, compared to the original uncleaned corn level, but did not impact (P &gt; 0.10) ochratoxin A. The resultant screenings had nearly 4 times the aflatoxin (4,224 ppb) and 7.5 times the fumonisin concentration (60.4 ppm) as the uncleaned corn. In Experiment 2, cleaning reduced (P &lt; 0.05) fumonisin concentration by 32%. The resultant screenings had 19.6 times the fumonisin concentration (65.4 ppm) as the uncleaned corn. To determine the effect that cleaning corn may have on nursery pig growth performance, 360 nursery pigs were used in Experiment 3 to evaluate the impact of cleaning or pelleting on growth performance. Treatments were arranged in a 2 × 3 factorial with corn type (uncleaned vs. cleaned) and feed form (mash vs. pelleted from either mill A or B). Neither cleaning corn nor pellet mill type affected (P &gt; 0.19) nursery pig growth performance. Pelleting improved (P &lt; 0.0001) gain to feed ratio (G:F) by 7.6% compared to mash diets. These data suggest that cleaning is an effective method to legally reduce aflatoxin and fumonisin concentration, but does not impact animal growth performance. Screenings should be used cautiously when feeding to animals.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 198-199
Author(s):  
Hansol Kim ◽  
Eunjeong Jang ◽  
Sang Yun Ji ◽  
Beob Gyun G Kim

Abstract Sufficient supply of dietary phosphorus (P) is critical for maximizing muscle and bone growth of pigs. The objective was to compare standardized total tract digestible (STTD) P requirements of growing pigs determined in the experiments and those estimated using modeling approach. Fifty-two experiments in the literature that empirically determined P requirements of pigs were employed. The basis for the determination of P requirements were growth performance (average daily gain or gain to feed ratio; n = 34) and bone development (n = 23). Based on the STTD P in the feed ingredients provided in NRC (2012) and ingredient composition used in the experiments, P requirements presented as total P, available P, and true total tract digestible P were converted to STTD P requirements. To obtain STTD P requirements (g/d) suggested by NRC (2012) for grow-finishing pigs (body weight &gt; 20 kg), mean body weight and sex indicated in the experiments were input into the NRC model. The statistical model for comparing the empirical data and the NRC requirements included the basis for determining P requirements in the experiments as a fixed variable and body weight as a random variable. To quantify the deviations between NRC STTD P requirement estimates and empirically determined STTD P requirements, mean percentage difference was calculated. The STTD P requirements empirically determined based on growth performance were greater than the NRC STTD P requirement estimates (5.89 vs. 4.61 g/d, SEM = 0.27; P &lt; 0.001). Moreover, the bone development-based STTD P requirements were greater than the NRC STTD P requirement estimates (6.63 vs. 4.46 g/d, SEM = 0.42; P &lt; 0.001). In conclusion, the standardized total tract digestible P requirements suggested by the NRC are less than the experimentally determined requirements.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 60-61
Author(s):  
Carine M Vier ◽  
Ning Lu ◽  
Gustavo Silva ◽  
Luis E Zaragoza ◽  
Brandon Knopf ◽  
...  

Abstract Our objective was to determine the effects of increasing dietary standardized ileal digestible (SID) lysine (Lys) on the growth performance of late nursery pigs. A total of 1,125 pigs (PIC 337×Camborough, initially 12.0±0.66 kg) were used in a 21-d study. The pigs used in the study were sired by boars ranked in the top 15% of a selected PIC elite boar stud based on index. Pens of pigs were blocked by body weight and randomly allotted to 1 of 5 treatments containing 0.95, 1.10, 1.20, 1.35, and 1.50% of SID Lys. Diets were corn-soybean meal-based and contained 2,480 Kcal of NE/kg. Treatments were achieved with increasing feed-grade amino acids. There were 9 mixed gender pens per treatment and 25 pigs per pen. Data were analyzed using generalized linear and nonlinear mixed models with pen as the experimental unit. Competing models included linear, quadratic polynomial (QP), broken-line linear (BLL), and broken-line quadratic (BLQ). Increasing SID Lys concentration improved average daily gain (ADG, linear, P &lt; 0.001) and gain to feed ratio (G:F, quadratic, P = 0.011). The best-fitting models for ADG were QP and BLL. The QP model estimated the maximum ADG at 1.43% (95% CI: 1.12 to &gt;1.50%), with 99% of maximum ADG achieved at 1.27%. The BLL plateau was estimated at 1.31% (95%CI: 1.06 to &gt;1.50%). The best-fitting models for G:F were QP, BLL, and BLQ. The QP model estimated the maximum G:F at 1.48% (95%CI: 1.23 to &gt;1.50%), with 99% of maximum G:F achieved at 1.24%. The BLL plateau was estimated at 1.30% (95% CI: 1.18 to 1.41%), whereas the BLQ plateau was estimated at 1.36% (95%CI: 1.14 to &gt;1.50%). In conclusion, the estimated optimum SID Lys concentration for 12- to 26-kg pigs sired by high index boars ranged from 1.30 to 1.48%, depending on the response criteria and statistical model.


2020 ◽  
Vol 4 (2) ◽  
pp. 694-707
Author(s):  
Henrique S Cemin ◽  
Mike D Tokach ◽  
Steve S Dritz ◽  
Jason C Woodworth ◽  
Joel M DeRouchey ◽  
...  

Abstract Four experiments were conducted to determine the effects of increasing soybean meal (SBM) level in diets with or without 25% distillers dried grains with solubles (DDGS) on growth performance of nursery pigs raised in university or commercial facilities. Treatments were arranged in a 2 × 3 factorial with main effects of SBM (27.5%, 32.5%, or 37.5% of the diet) and DDGS (0% or 25% of the diet). A total of 296, 2,502, 4,118, and 711 pigs with initial body weight (BW) of 10.6, 11.7, 12.5, and 12.3 kg were used in Exp. 1, 2, 3, and 4, respectively. There were 10, 16, 13, and 12 replicates per treatment in Exp. 1, 2, 3, and 4, respectively. After weaning, pigs were fed common diets for approximately 21 d. Then, pens of pigs were assigned to treatments in a randomized complete block design with BW as the blocking factor and experimental diets were fed for 21 d. Pigs were weighed and feed disappearance measured to calculate average daily gain (ADG), average daily feed intake (ADFI), gain-to-feed ratio (G:F), and caloric efficiency (CE). Data were analyzed using the GLIMMIX procedure of SAS with block as a random effect and treatment as a fixed effect. Single degree-of-freedom contrasts were constructed to test the linear and quadratic effects of increasing SBM and their interactions with DDGS. Pigs used in all experiments did not undergo major health challenges during the experimental period and due to the low number of mortality and cull events, statistical analysis was not performed on these variables. The average cull rate was 0.7%, 0.5%, 0.2%, and 0%, and the mortality rate was 0.7%, 0.3%, 0.4%, and 0% in Exp. 1–4, respectively. There were interactions (P ≤ 0.039) between SBM and DDGS for G:F and CE in Exp. 2 and for ADG and ADFI in Exp. 3. These were mostly driven by increasing SBM negatively affecting performance in a greater magnitude when diets contained DDGS compared to diets without DDGS. The main effects of DDGS and SBM were more consistently observed across experiments. Pigs fed diets with 25% DDGS had decreased (P ≤ 0.001) ADG and ADFI in all experiments, as well as poorer (P ≤ 0.028) G:F and CE except for Exp. 3. Feeding increasing amounts of SBM generally did not result in any major impact in ADG but consistently improved (linear, P ≤ 0.078) G:F and CE across experiments.


2017 ◽  
Vol 60 (No. 12) ◽  
pp. 675-682
Author(s):  
S. Mohana Devi ◽  
SC Kim ◽  
IH Kim

A total of 120 weanling pigs [(Landrace &times; Yorkshire) &times; Duroc], 21 days of age with an average initial body weight (BW) of 6.52 &plusmn; 0.22 (SE) kg were selected to investigate the effects of extruded rice product as a replacement for dried whey on growth performance, coefficient of total tract apparent digestibility (CATTD), blood profiles, faecal shedding of Lactobacillus and Escherichia coli (the microbial counts of digesta were expressed as log<sub>10</sub> colony forming units per gram), and faecal scores of weanling pigs. Pigs were randomly allocated to one of four dietary treatments, with six replicates per treatment and five pigs per pen. Pigs in the control group were fed a diet based on corn, soybean, and 20% dried whey. Experimental groups received the same diet as the control group, but dried whey was replaced by 3%, 6%, and 9% extruded rice. Throughout the experimental period (six weeks), no differences were observed in the average daily gain, average daily feed intake, and gain/feed ratio. Pigs fed 6% and 9% extruded rice had a lower (P &lt; 0.05) CATTD than pigs fed the control diet on Day 14. The blood creatinine concentration of pigs fed 9% extruded rice was higher (P &lt; 0.05) than that of pigs in the control group on Day 14. Pigs fed the diets containing 6% and 9% extruded rice had decreased (P &lt; 0.05) faecal E. coli counts on Day 14 compared with pigs fed the control diet. The current results indicate that feeding extruded rice can decrease faecal E. coli counts without negative effects on growth performance in weanling pigs.


2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Leigh A Ruckman ◽  
Amy L Petry ◽  
Stacie A Gould ◽  
John F Patience

Abstract The objective of this experiment was to compare the effects of spray-dried plasma protein (SDPP) and dried egg protein (DEP), without (AB−) or with (AB+) in-feed antibiotics, on growth performance and markers of intestinal health in nursery pigs raised in commercial conditions. This 42-d experiment utilized 1,230 pigs (4.93 ± 0.04 kg body weight; approximately 15–18 d of age). Pigs were randomly assigned to one of six dietary treatments that were arranged as a 2 × 3 factorial of in-feed antibiotics (AB− vs. AB+) and a specialty protein additive (none [CON], porcine SDPP, or DEP). Diets were fed in four phases with phases 3 and 4 as a common diet across all treatments. Specialty protein additives were fed in phases 1 (0–13 d; 3% SDPP, and 0.20% DEP) and 2 (13–26 d; 2% SDPP, and 0.10% DEP). Antibiotics were fed in phases 1–3 (662 mg chlortetracycline [CTC]/kg, 28 mg carbadox/kg, and 441 mg CTC/kg, respectively). Ileal tissue and blood samples were collected from 48 pigs (8 per treatment) on d 20. Data were analyzed using PROC MIXED of SAS (9.4) with pen as the experimental unit; protein additives, antibiotics, and their interaction were fixed effects and block was a random effect. The pigs experienced naturally occurring health challenges in weeks 2 and 4. In the AB− diets, SDPP and DEP increased average daily gain (ADG; P = 0.036) and average daily feed intake (ADFI; P = 0.040) compared to CON; in the AB+ diets, neither SDPP nor DEP increased ADG or ADFI compared to CON but SDPP did increase these parameters over DEP. The SDPP and DEP diets decreased the number of individual medical treatments compared to CON (P = 0.001). The AB+ increased ileal mucosal interleukin (IL)-1 receptor antagonist (P = 0.017). Feeding DEP reduced the concentration of mucosal IL-1β compared to CON, but not SDPP (P = 0.022). There was a trend for SDPP and DEP to increase villus height:crypt depth compared to CON (P = 0.066). Neither antibiotics or protein additive affected serum malondialdehyde concentration or ileal mRNA abundance of claudin-3 or 4, occludin, or zonula occludens-1 (P &gt; 0.10). In conclusion, SDPP and DEP improved growth performance of weaned pigs in the absence of antibiotics but neither improved growth compared to CON when feeding standard antibiotic levels. The specialty proteins had a positive effect on health; specialty proteins and antibiotics were able to modulate some markers of intestinal inflammation and morphology.


2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 304-304
Author(s):  
Tylo J Kirkpatrick ◽  
Sierra L Pillmore ◽  
Kimberly Cooper ◽  
Travis Tennant ◽  
Ty Lawrence

Abstract This experiment was designed to study the effect of days on feed and an aggressive implant strategy on Jersey steer growth performance. Steers (n = 30; start of trial body weight (BW) 183 ± 43 kg) were randomly assigned to one of two treatments; negative control (CON) or implanted with Revalor 200 every 70 d (REV; d 0, d 70, d 140, d 210, d 280, d 350) for a total of 6 implants. Steers were weighed every 35 d and daily feed delivery was recorded daily. Data for dry matter intake (DMI) and gain to feed ratio (G:F) were analyzed via a mixed model; the fixed effects were day and treatment. Live growth BW and average daily gain (ADG) used day as the repeated measure and animal as the subject in a repeated measures analysis. Change in BW increased linearly (P &lt; 0.01); treatments differed in BW from d 280 through d 350 (P &lt; 0.01). Average daily gain decreased (P &lt; 0.01) linearly and differed (P &lt; 0.01) at d 70, d 140, d 280, and d 350, but not (P ≥ 0.10) at d 210 or d 420. Dry matter intake was greater (P &lt; 0.05) for REV steers (7.6 kg/d) than CON (6.8 kg/d). Gain to feed ratio did not differ (P ≥ 0.78) between CON steers (0.13 kg/kg dry matter (DM)) and REV (0.14 kg/kg DM) steers, yet G:F differed (P &lt; 0.01) amongst periods (d 70 = 0.21 kg/kg, d 140 = 0.16 kg/kg, d 210 = 0.15 kg/kg, d 280 = 0.13 kg/kg, d 350 = 0.08 kg/kg, d 420 = 0.08 kg/kg). Aggressively implanting Jersey steers improved growth performance by 9.6%, 13.2%, 11.3%, and 7.7% for BW, ADG, DMI, and G:F, respectively.


2019 ◽  
Vol 99 (1) ◽  
pp. 66-73 ◽  
Author(s):  
Jin Ho Cho ◽  
Shu Dong Liu ◽  
Won Yun ◽  
Kwang Sik Kim ◽  
In Ho Kim

A total of 125 crossbred pigs with an initial body weight (BW) of 7.66 ± 1.30 kg were randomly distributed into one of five dietary treatments. Each treatment had five replicate pens with five pigs per pen. Treatments were as followed: (1) CON, control diet; (2) zinc oxide (ZO), CON + 0.3% ZO; (3) ZOM, CON + 0.3% ZO + 0.1% microencapsulated organic acids and pure botanicals (MOP); (4) microencapsulated zinc oxide (MZO), CON + 0.03% MZO; and (5) MZOM, CON + 0.03% MZO + 0.1% MOP. The MZO group had higher (P = 0.03) final BW than ZO group and also had higher (P = 0.04, 0.01) average daily gain and gain/feed ratio compared with ZO group during days 15–34 and throughout the experimental period. The MZO and MZOM had higher (P < 0.05) apparent total tract digestibility (ATTD) of dry matter (DM) and energy than ZO. Less (P < 0.05) feces Escherichia coli shedding was observed in the ZOM and MZOM diets compared with CON; the MZO had lowered (P = 0.001) zinc level in feces than ZO and CON. In conclusion, results indicated that supplementation with 0.3% MZO could improve the growth performance and ATTD of DM; inclusion of 0.1% MOP could decrease feces E. coli shedding and also decrease the zinc level in feces in weanling pigs.


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