scholarly journals 453 Biological responses to non-coated and coated steroidal implants containing equal doses and ratios of trenbolone acetate and estradiol benzoate in beef steers.

2018 ◽  
Vol 96 (suppl_3) ◽  
pp. 234-235
Author(s):  
Z Smith ◽  
J Baggerman ◽  
J Kim ◽  
K Wellmann ◽  
B Johnson
Keyword(s):  
Estradiol Benzoate ◽  
Beef Steers ◽  
Trenbolone Acetate ◽  
Biological Responses

scholarly journals PSIII-8 Impact of SYNOVEX® ONE GRASS implantation during suckling on pre-weaning calf growth performance

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 239-239
Author(s):  
Shane Newton ◽  
Payton Dahmer ◽  
Larry Corah ◽  
Keith Harmoney ◽  
John Jaeger ◽  
...  
Keyword(s):  
Growth Performance ◽  
Random Effect ◽  
Cost Effective ◽  
Recent Decade ◽  
Estradiol Benzoate ◽  
Beef Steers ◽  
Weaning Weight ◽  
Trenbolone Acetate ◽  
Calf Growth ◽  
Randomized Design

Abstract Historic data supports the use of pre-weaning implants to maximize beef calf weaning weight, but their use has declined over the recent decade. A total of 96 beef steers (initially 85.2 kg BW and > 45 d of age) were used in a 168-d study to evaluate the effects of Synovex C® implantation during suckling on pre-weaning calf growth performance. At initial processing, calves were individually weighed and allotted in a completely randomized design to one of two treatments: 1) not implanted (control) or 2) implanted with 150 mg of trenbolone acetate and 21 mg of estradiol benzoate (SYNOVEX® ONE GRASS, Zoetis, Kalamazoo, MI). All calves were weighed on d 0 (implantation), 83, 126 and 168 (weaning), with ADG calculated for each period. Data were analyzed using the GLIMMIX procedure of SAS (v9.4, Cary, NC). There were 48 replicates per treatment, with grazing location as a random effect. While there were no detected differences in BW during the initial phases (P > 0.10), implanted calves tended to have greater (P = 0.100) greater weaning weight than non-implanted calves (279 vs. 265 kg, respectively). Calves implanted with SYNOVEX® ONE GRASS had 0.8, 0.12, and 0.16 kg/d greater (P < 0.05) ADG than those that were not implanted in all three phases. This resulted in an average of 0.10 kg/d greater (P = 0.002) ADG in implanted calves overall compared to the control. In conclusion, this research showed significant increases in suckling calf ADG in implanted calves compared to their non-implanted counterparts, which led to a tendency for 14-kg greater weaning weights. Additional research is warranted to consider the post-weaning growth and impact of re-implanting, but this data reinforces previous literature that suckling calf implantation continues to be cost effective for cow-calf producers.

scholarly journals Feedlot performance and biological responses to coated and non-coated steroidal implants containing trenbolone acetate and estradiol benzoate in finishing beef steers123

2019 ◽  
Vol 97 (11) ◽  
pp. 4371-4385 ◽  
Author(s):  
Zachary K Smith ◽  
Jongkyoo Kim ◽  
Bradley J Johnson
Keyword(s):  
Androgen Receptor ◽  
Repeated Measures ◽  
Block Design ◽  
Housekeeping Genes ◽  
Estradiol Benzoate ◽  
Tissue Growth ◽  
Trenbolone Acetate ◽  
Biological Responses ◽  
Randomized Design ◽  
Igf I

Abstract Predominately Angus steers (n = 24; initial BW = 435 ± 28.3 kg) were used to evaluate non-coated (NC) and coated implants (CI) containing equal amounts of trenbolone acetate (TBA; 200 mg) and estradiol benzoate (EB; 28 mg) in finishing steers on sera metabolite responses, gene expression, and immunohistochemical analyses of the Longissimus muscle (LM). Performance data were analyzed as a randomized complete block design, and all other data were analyzed as repeated measures for a completely randomized design. Treatments were no implant (NI), NC (Synovex-PLUS; Zoetis, Parsippany, NJ), and CI (Synovex-One Feedlot) implant. There were 2 pen replicates per treatment (n = 4 steers/pen). LM biopsies, blood, and BW were collected before feeding on days 0, 14, 28, 56, 84, 112, and 133, with final BW being captured on day 140. Genes of interest were determined by RT-qPCR using two housekeeping genes. Sera was analyzed for estradiol-17β (E2),17β-trenbolone (TbOH), insulin-like growth factor 1 (IGF-I), NEFA, and urea-N (SUN). An α of 0.10 determined significance for performance and sera data; α of 0.05 was used for gene and histology data. No performance differences (P ≥ 0.10) were detected. An implant × day interaction (P ≤ 0.10) for E2, IGF-I, and SUN was detected; implants elevated (P ≤ 0.10) E2, 17β-TbOH, and IGF-I; and decreased SUN across day of the study, meaning sera metabolites are not altered with time on feed. An implant × day interaction was detected for myogenic factor 5 (MYF-5) positive cells and proportions of MHCIIX. In LM, CI had greater (P < 0.10) IGF-I in LM over NI. CI increased (P < 0.05) G protein-coupled estrogen receptor 1 (GPER1) expression, as well as, GPER1 semi-quantitative scores over NI and NC. An implant × day interaction (P ≤ 0.05) for estrogen and androgen receptor-positive nuclei was detected; implants had increased (P ≤ 0.05) estrogen and androgen receptor-positive nuclei compared to NI. CIs increase genes associated with muscle tissue growth.

scholarly journals 179 Using a 100% Dried Distillers Grains Cube as a Supplement for Steers Grazing Mixed Grass Prairie in Oklahoma

2020 ◽  
Vol 98 (Supplement_2) ◽  
pp. 46-46
Author(s):  
Zane N Grigsby ◽  
Paul A Beck ◽  
Stacey A Gunter
Keyword(s):  
Animal Health ◽  
Late Summer ◽  
Estradiol Benzoate ◽  
Positive Control ◽  
Negative Control ◽  
Early Summer ◽  
Trenbolone Acetate ◽  
Mixed Grass Prairie ◽  
Mixed Grass ◽  
Main Plot

Abstract This research was conducted to determine effects of supplementation and implanting on BW gain by steers grazing mixed grass prairie (n = 12 pastures, 19.9 ± 0.7 ha) in northwest Oklahoma. Three main plot treatments were: 1) Negative Control (NC), no supplementation, 2) Positive Control (PC), supplemented with DDGS cubes, 1.8 kg/steer on alternate days in late summer, 3) High Supplement (HS), 1/3 increase in stocking rate with 0.75% BW supplemental DDGS cubes all season. Steers (n = 125, BW = 223.1 ± 23.2 kg) were stocked at 2.2 ha/steer for PC and NC, 1.3 ha/steer for HS. Grazing was from May 17 – September 27 (132 d). All steers were implanted with 200 mg progesterone and 20 mg estradiol benzoate (SYN, Synonvex S, Zoetis Animal Health) on May 17. On July 18 three reimplant treatments were applied: 1) no reimplant; 2) SYN; or 3) 40 mg trenbolone acetate and 8 mg estradiol (Revalor G, Merck Animal Health). Data were analyzed using the PROC MIXED in SAS as a split-plot experimental design. In early summer HS had 0.26 kg greater (P &lt; 0.01) ADG than NC and PC. Late summer gains of PC were 0.33 kg/d more (P ≤ 0.01) than NC; and HS gained 0.49 and 0.16 kg/day more (P ≤ 0.04) than NC and PC, respectively. Gain per hectare for PC (46 kg/ha) were greater (P &lt; 0.01) than NC (35 kg/ha) and more than doubled (P &lt; 0.01) with HS (89 kg/ha). Reimplanting had no effect on ADG (P ≥ 0.28). Late season supplementation with PC resulted in supplemental efficiency of 2.7 kg supplement/kg added gain compared with NC. Increased stocking rates with season long supplementation in HS resulted in supplemental efficiency of 3.8 kg supplement/kg added gain per hectare. Based on these data, a 100% DDGS cube is an effective supplement option to increase BW gain during the late summer or increase carrying capacity and gain during the summer grazing period in northwestern Oklahoma.

PSX-B-5 Effect of replacement of dry-rolled corn with un-processed rye on growth performance, efficiency of dietary net energy utilization, and carcass traits of finishing heifers

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 458-459
Author(s):  
Keith M Buckhaus ◽  
Warren C Rusche ◽  
Zachary K Smith
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Block Design ◽  
Average Daily Gain ◽  
Estradiol Benzoate ◽  
Energy Utilization ◽  
Net Energy ◽  
Final Body Weight ◽  
Trenbolone Acetate ◽  
Finishing Diets

Abstract Continental × British beef heifers were used in a randomized complete block design experiment to evaluate the effects of replacing dry-rolled corn with unprocessed rye on growth performance, efficiency of dietary net energy (NE) utilization, and carcass trait responses in finishing heifers. Heifers (n = 56; 433 ± 34.0 kg) were transported 241 km from a regional sale barn to the Ruminant Nutrition Center in Brookings, SD. Heifers were blocked by weight grouping and then allotted to pens (n = 7 heifers/pen and 4 pens/treatment). Treatments included a finishing diet that contained 60% grain (DM basis) as dry-rolled corn (DRC) or unprocessed rye grain (RYE). On d 14, heifers were consuming the final diet and were implanted with 200 mg of trenbolone acetate and 28 mg of estradiol benzoate (Synovex-Plus, Zoetis, Parsippany, NJ). RYE heifers had decreased (P ≤ 0.01) final body weight, average daily gain, and gain efficiency; but tended (P = 0.08) to have a greater dry matter intake compared to DRC. RYE had decreased (P ≤ 0.01) observed dietary NE and decreased (P ≤ 0.01) observed-to-expected dietary NE ratio for maintenance and gain compared to DRC. Dressing percentage, 12th rib fat thickness, ribeye area, and the distribution of USDA yield and quality grades were not altered (P ≥ 0.12) by diet. Hot carcass weight, yield grade, estimated empty body fat (EBF), and body weight at 28% EBF decreased (P ≤ 0.02) and retail yield increased (P= 0.01) in RYE compared to DRC. These data indicate that unprocessed rye is a palatable feed ingredient for inclusion in finishing diets for beef cattle and that rye inclusion only minimally influences carcass quality. The feeding value of unprocessed rye is considerably less (21.4%) than that of dry-rolled corn using current standards and approximately 91% of the NE value of processed rye.

Production responses to various doses and ratios of estradiol benzoate and trenbolone acetate implants in steers and heifers.

1995 ◽  
Vol 73 (10) ◽  
pp. 2873 ◽  
Author(s):  
R C Herschler ◽  
A W Olmsted ◽  
A J Edwards ◽  
R L Hale ◽  
T Montgomery ◽  
...  
Keyword(s):  
Estradiol Benzoate ◽  
Trenbolone Acetate

Biological responses of beef steers to steroidal implants and zilpaterol hydrochloride1

2014 ◽  
Vol 92 (8) ◽  
pp. 3348-3363 ◽  
Author(s):  
S. L. Parr ◽  
T. R. Brown ◽  
F. R. B. Ribeiro ◽  
K. Y. Chung ◽  
J. P. Hutcheson ◽  
...  
Keyword(s):  
Beef Steers ◽  
Biological Responses

scholarly journals The effects of a combined implant of trenbolone acetate and oestradiol-17β on protein and energy metabolism in growing beef steers

1985 ◽  
Vol 54 (3) ◽  
pp. 681-694 ◽  
Author(s):  
G. E. Lobley ◽  
Alexmary Connell ◽  
G. S. Mollison ◽  
A. Brewer ◽  
C. I. HARRIS ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Amino Acid ◽  
Total Energy ◽  
Protein Degradation ◽  
Whole Body ◽  
Beef Steers ◽  
Body Protein ◽  
Trenbolone Acetate ◽  
N Retention ◽  
Energy Retention

1. The effects on growth performance, energy and nitrogen retention, and leucine metabolism of a subcutaneous combined implant of 140 mg trenbolone acetate (TBA)+20 mg oestradiol-17β (OE) have been examined in Hereford × Friesian beef steers (280–520 kg). Comparisons were made both with the same animals before implantation and with untreated control animals maintained under similar physiological and nutritional conditions.2. Over a 10 week period the implanted steers showed an improvement in rate of live-weight gain (LWG) of 0.5–0.6 with an even greater proportional increase in N retention compared with control animals. Total energy retention was unaffected and thus the ratio, protein energy: total energy gain was 0.43 for implanted steers compared with 0.26 for untreated animals.3. Estimates of protein synthesis and protein oxidation were obtained from the specific radioactivities of blood free-leucine and exhaled carbon dioxide during continuous infusions of [1-14C]leucine. Whole-body protein synthesis, based on metabolic size, and amino acid fractional oxidation remained similar for control steers throughout the experiment. Steroid-treated steers showed a slight decline in synthesis which was significant (P < 0.05) at week + 5 post-implant while amino acid oxidation was significantly lower at weeks +2 (P < 0.01) and + 5 (P < 0.05) compared with control animals. The ratio, protein deposition: protein synthesis was 0.05 for control animals but 0.08–0.10 for steroid-treated animals after implantation.4. There was a slight decrease in urinary NT-methylhistidine elimination after implantation which suggested that muscle protein degradation may be reduced although the estimated decrease was insufficient to account for the total improvement in growth rate and N retention.5. The results suggest that for both control and treated steers, less than 0.5 of total urine N elimination was derived directly from tissue catabolism of protein and amino acids.6. The combined action of the exogenous steroids in the promotion of protein gain, primarily through a decrease in total protein degradation with little alteration of total energy retention, is compared with present understanding of the role of the endogenous sex hormones.

116 Effect of Coated and Non-coated Steroidal Implants on Growth Performance, Dietary Net Energy Utilization and Carcass Traits of Feedlot Finishing Steers

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 36-37
Author(s):  
Elizabeth M Buckhaus ◽  
Zachary K Smith
Keyword(s):  
Growth Performance ◽  
Carcass Traits ◽  
Estradiol Benzoate ◽  
Corn Silage ◽  
Energy Utilization ◽  
Carcass Weight ◽  
Net Energy ◽  
Trenbolone Acetate ◽  
Coated Implant ◽  
Dietary Treatments

Abstract Maine-Anjou x Angus steers (n = 156, initial BW 366 ± 37.2 kg) were used in a 132-d finishing experiment at the Ruminant Nutrition Center in Brookings, SD. Steers were weighed on two consecutive days and assigned into 5 weight blocks. Within each weight block steers were randomly assigned to two implant types (equal steroidal hormone dose; both from Zoetis, Parsippany, NJ) and two dietary treatments in a 2 × 2 factorial arrangement. Implant treatments consisted of 1) Coated implant, 200 mg trenbolone acetate (TBA), 28 mg estradiol benzoate (EB) (Synovex ONE Feedlot, ONE) or 2) Non-coated implant, 200 mg TBA, 28 mg EB (Synovex PLUS; PLUS), placed in the left ear. Dietary treatments were 1) 15% or 2) 30% corn silage (DM basis). No interaction between implant and corn silage inclusion was observed for carcass-adjusted (hot carcass weight / 0.63) growth performance, dietary net energy (NE) utilization or carcass traits (P ≥ 0.16). Bunks were managed using a slick bunk approach and all diets contained (DM basis) 33 mg/kg monensin sodium. Implant status was checked on d 28 by a single trained evaluator; steers with missing implants were immediately re-implanted. There was no difference in carcass-adjusted growth performance between implants (P ≥ 0.85). There were no differences in observed NE or the observed-to-expected ratio of NE for either growth or maintenance (P ≥ 0.90). No differences were observed for dressing percent, hot carcass weight, ribeye area, or rib fat (P ≥ 0.22). Marbling differed between implant treatments (433 to 466 ± 8.7; P = 0.01) for PLUS and ONE respectively. Implanting cattle with a coated implant had no detrimental effect on growth performance or carcass traits, but it did increase marbling scores.

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