Refugees and populations exposed to mass conflict

2020 ◽  
pp. 1401-1412
Author(s):  
Mina Fazel ◽  
Susan Rees ◽  
Derrick Silove
Keyword(s):  
Mental Illness ◽  
Forced Migration ◽  
Post Traumatic Stress ◽  
Unaccompanied Minors ◽  
Large Populations ◽  
Adults And Children ◽  
Short And Long Term ◽  
Post Traumatic ◽  
Forms Of Violence

The mental health implications of forced migration because of conflict, leading to large populations of displaced and refugee adults and children, are the focus of this chapter. The factors leading to forced migration are discussed in light of their impacts on mental illness, both in the short and long term. Rates of mental illness, especially depression, anxiety disorders, and post-traumatic stress disorder, are raised in these populations, with exposure to torture and other forms of violence the strongest predictors for subsequent disorders. A framework for assessment is proposed, and a discussion of the cycles of violence that can impact on children and women raised. Specific populations of note are considered, including those in immigration detention, unaccompanied minors, and trafficked populations. The range of interventions that have been trialled to treat mental illness in refugee populations are presented.

L-Carnitine prevents memory impairment induced by post-traumatic stress disorder

2021 ◽  
pp. 1-9
Author(s):  
Karem H. Alzoubi ◽  
Arwa M. Al-Dekah ◽  
Saied Jaradat ◽  
Nasr Alrabadi
Keyword(s):  
Oxidative Stress ◽  
Rat Model ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Memory Impairment ◽  
Stress Disorder ◽  
Post Traumatic Stress ◽  
Short And Long Term ◽  
Post Traumatic

Background: Post-traumatic stress disorder (PTSD) is a genuine obstructing mental disorder. As indicated by the name, it is related to the patients’ stress augmented by life-threatening conditions or accidents. The PTSD has linked to oxidative stress that can result in neurodegeneration. L-carnitine (L-CAR) is known for its antioxidant properties, which can protect against neuronal damage. Objective: In the current study, we investigated the beneficial effects of L-CAR on the memory impairment induced by PTSD using a rat model. Methods: A model of single-prolonged stress (a cycle of restraining, forced swimming, rest, and finally diethyl ether exposure for 2 h, 20 min, 15 min, and 1–2 min, respectively) was used to induce PTSD-like behavior. Intraperitoneal L-CAR treatment (300 mg/kg/day) was introduced for four weeks. Both memory and special learning were evaluated utilizing the radial arm water maze (RAWM). Moreover, the levels of glutathione peroxidase (GPx), glutathione reduced (GSH), and glutathione oxidized (GSSG) were assessed as biomarkers oxidative stress in the hippocampus. Results: The results demonstrated that both the short and long-term memories were impaired by PTSD/SPS model (P <  0.05), while L-CAR treatment prevented this memory impairment in PTSD rats. Besides, L-CAR prevented the reduction in GPx activity and increase in GSSG, which were altered in the hippocampus of the PTSD/SPS rats (P <  0.05). Levels of GSH were not changed in PTSD and/or L-CAR rats. Conclusions: L-CAR administration prevented short- and long-term memories’ impairments induced in the PTSD/SPS rat model. This is probably related to its antioxidant effects in the hippocampus.

scholarly journals Short and Long-Term Effects of Cannabis on Symptoms of Post-Traumatic Stress Disorder

2020 ◽  
Vol 274 ◽  
pp. 298-304
Author(s):  
Emily M. LaFrance ◽  
Nicholas C. Glodosky ◽  
Marcel Bonn-Miller ◽  
Carrie Cuttler
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Long Term Effects ◽  
Post Traumatic Stress ◽  
Short And Long Term ◽  
Post Traumatic

scholarly journals Paternal and maternal long-term psychological outcomes after uterine artery embolization for severe post-partum hemorrhage

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maude Bernasconi ◽  
Béatrice Eggel-Hort ◽  
Antje Horsch ◽  
Yvan Vial ◽  
Alban Denys ◽  
...  
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Uterine Artery Embolization ◽  
Stress Disorder ◽  
Post Partum ◽  
Post Traumatic Stress ◽  
Artery Embolization ◽  
Increased Risk ◽  
Post Traumatic

AbstractThis study intend to compare the long-term psychological impact (depression, post-traumatic stress disorder) on both partners between patients that underwent uterine artery embolization (UAE) for post-partum hemorrhage (PPH) and uneventful deliveries. Women who experienced severe PPH treated by UAE in our institution between 2003 and 2013 were identified in our obstetrical database. These cases were matched to controls with uneventful deliveries. Matching criteria were maternal age, parity, ethnicity, year of delivery, birthweight, gestational age and mode of delivery. Patients and their partners completed validated questionnaires measuring post-traumatic stress (TSQ), as well as depression symptoms (MINI). A total of 63 cases of PPH and 189 matched controls (1:3) participated in a study exploring gynecological and obstetrical outcomes. With a mean of 8 years post-index delivery, patients after PPH showed increased risk of depression (p = 0.015) and post-traumatic stress disorder (22.2% versus 4.8%, p < 0.005) compared to controls. PPH remains strongly associated with post-traumatic stress disorder, even after adjustment for depression (adjusted odds ratio 5.1; 95% confidence intervals 1.5–17.5). Similarly, partners of patients with PPH showed a propensity to depression (p = 0.029) and post-traumatic stress disorder (11.5% versus 1.5%, p = 0.019). In conclusion, both women and their partners are at increased risk of long-term psychological adverse outcomes after PPH. Couples may benefit from psychological support.

scholarly journals Likely Exacerbation of Psychological Disorders from Covid-19 Response

2021 ◽  
Vol 12 ◽  
pp. 215013272110167
Author(s):  
Tara Rava Zolnikov ◽  
Tanya Clark ◽  
Tessa Zolnikov
Keyword(s):  
Psychological Disorders ◽  
Emotional Reactions ◽  
Post Traumatic Stress ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Current State ◽  
The Face ◽  
Adults And Children ◽  
Post Traumatic ◽  
Anxiety Depression

Anxiety and fear felt by people around the world regarding the coronavirus pandemic is real and can be overwhelming, resulting in strong emotional reactions in adults and children. With depressive and anxiety disorders already highly prevalent in the general population (300 million worldwide), depression and/or anxiety specifically because of the pandemic response is likely. Moreover, the current state of panic in the face of uncertainty is apt to produce significant amounts of stress. While this situation has the potential to cause psychological disorders in previously unaffected populations, perhaps more impactful is the exacerbation of symptoms of many existing disorders including anxiety, depression, post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD) and hoarding disorder.

Long-Term Pharmacotherapy for Post-Traumatic Stress Disorder

CNS Drugs ◽  
2006 ◽  
Vol 20 (6) ◽  
pp. 465-476 ◽  
Author(s):  
Lori L Davis ◽  
Elizabeth C Frazier ◽  
Raela B Williford ◽  
Jason M Newell
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Post Traumatic Stress ◽  
Post Traumatic
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