scholarly journals Epidemiology and risk factors for nosocomial Non-Candida albicanscandidemia in adult patients at a tertiary care hospital in North China

2015 ◽  
Vol 53 (7) ◽  
pp. 684-690 ◽  
Author(s):  
Xiurong Ding ◽  
Donghui Yan ◽  
Wei Sun ◽  
Zhaoyin Zeng ◽  
Ruirui Su ◽  
...  
Keyword(s):  
Risk Factors ◽  
North China ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Adult Patients ◽  
Care Hospital

scholarly journals 1702. Prevalence and Risk Factors for Endogenous Fungal Endophthalmitis in Adult Patients with Candidemia at a Tertiary Care Hospital in South Korea Over 13 years

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S623-S623
Author(s):  
Jong Hun Kim ◽  
Jin Woong Suh ◽  
You Seung Chung ◽  
Young Kyung Yoon ◽  
Jang Wook Sohn ◽  
...  
Keyword(s):  
Risk Factors ◽  
South Korea ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Adult Patients ◽  
Ophthalmological Examination ◽  
Care Hospital ◽  
Fungal Endophthalmitis ◽  
Endogenous Fungal Endophthalmitis ◽  
Significant Difference

Abstract Background Endogenous fungal endophthalmitis is one of the critical complications of candidemia in adult patients. We conducted a study to investigate the prevalence and risk factors for endogenous fungal endophthalmitis in adult patients with candidemia. Methods Adult patients ≥19 years with candidemia who underwent ophthalmological examination after the diagnosis of candidemia at a tertiary care hospital in South Korea from 2006 to 2018 were enrolled, and clinical data were collected. Results There was a total of 152 adult patients with candidemia who underwent an ophthalmological examination. Endogenous fungal endophthalmitis was found in 29 patients (19.1%). Patients were categorized into two groups (Non-endophthalmitis [NE] and endophthalmitis [E]). Between two groups, there was no significant difference in terms of age, sex, underlying comorbidities. Also, no difference in clinical conditions at the diagnosis of candidemia was noted including concomitant bacteremia, presence of septic shock, receipt of recent surgery, presence of neutropenia, total parenteral nutrition, central venous catheter, urinary catheter, ventilator, dialysis, use of antibiotics, and Candida spp. colonization. However, there was a higher rate of abnormal alanine aminotransferase (ALT) in the E (35.7%) than in the NE (14.8%), P = 0.008. Moreover, the proportion of C. albicans candidemia was higher in the E (65.5%) than in the NE (35.8%), P = 0.003. In contrast, C. parapsilosis candidemia was more common in the NE (27.6%) than in the E (6.9%), P = 0.018. Although there was a trend of higher mortality rate in the E (51.7%) than in the NE (35.0%), no statistical significance was observed, P = 0.095. Multivariate logistic analysis showed C. albicans candidemia (odds ratio [OR] 4.122, 95% confidence interval [CI] 1.653–10.280, P = 0.002) and abnormal ALT (OR 3.839, 95% CI 1.427–10.333, P = 0.008) were significantly associated with E cases. Conclusion Endogenous fungal endophthalmitis occurred in 19% of adult patients with candidemia. C. albicans candidemia and abnormal ALT were significantly associated with endophthalmitis. Adult patients with candidemia caused by C. albicans or having abnormal ALT need to be closely monitored for the possibility of endophthalmitis. Disclosures All authors: No reported disclosures.

scholarly journals Metabolic syndrome and its socio demographic and behavioral correlates: a cross sectional study among adult patients attending medicine outpatient department in a tertiary care hospital, West Bengal

2019 ◽  
Vol 6 (4) ◽  
pp. 1585 ◽  
Author(s):  
Sanjoy Kumar Kunti ◽  
Santanu Ghosh ◽  
Amrita Samanta ◽  
Indranil Chakraborty
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
West Bengal ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Adult Patients ◽  
Care Hospital ◽  
Chi Square ◽  
Cross Sectional ◽  
Junk Foods

Background: Metabolic syndrome (MS) is a pre-condition for cardiovascular diseases and type 2 diabetes mellitus (T2DM) which are major contributors to morbidity and mortality worldwide.Methods: The cross-sectional, observational study was conducted to estimate the proportion of MS and to explore crucial risk factors for MS among adult patients attending medicine OPD in a tertiary care hospital in West Bengal. The estimated final sample size was 315. Baseline socio demographic information and information on risk factors for MS, such as dietary habit, physical activity status, substance use, intake of related drugs, and presence of co-morbidities were collected by interviewing the patients with the help of a predesigned, pretested, structured schedule. Anthropometric measurements such as weight, height, waist circumference recordings were taken, and blood pressure was measured.Results: About 64% of the final study population (210/330) suffered from MS. On bivariate analysis, significant association between female gender (df=1, Pearson chi-square=5.06, p=0.024), weekly frequency of consumption of junk foods (df=3, Pearson chi-square=10.40, p=0.015) and obesity according to BMI (independent samples Mann-Whitney U test, p=0.010) at 5% level of significance were observed. Performing binary logistic regression analysis, obesity according to BMI (AOR=1.388, 95% CI=1.064-1.810) was found to be significant.Conclusions: Majority of the population suffered from MS who were mostly female, obese and consumers of junk foods. Appropriate interventional measures in terms of life style modification both at community and at tertiary care level are the need of the hour.

scholarly journals Frequency, risk factors and materno-foetal outcomes among cases of Placenta previa at a tertiary care hospital: a two year study

2019 ◽  
Vol 8 (6) ◽  
pp. 2240
Author(s):  
Pamulaparthi Bindu Reddy ◽  
Gurram Swetha Reddy
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Tertiary Care Hospital ◽  
Placenta Previa ◽  
Tertiary Care ◽  
Previous History ◽  
Morbidity And Mortality ◽  
Care Hospital ◽  
Early Date

Background: Placenta previa refers to the presence of placental tissue that extends over the internal cervical os.  Placenta previa is linked to maternal hypovolemia, anaemia, and long hospital stay and with prematurity, low birth weight, low APGAR score in newborn. So it is very important to identify the condition at an early date to warn the condition thereby reducing the maternal and foetal morbidity and mortality. The present study was aimed to estimate the prevalence of PP, its associated predisposing risk factors and maternal morbidity, mortality and the perinatal outcome.Methods: A prospective observational study for two years was conducted at a tertiary care hospital. Pregnant mothers with >28 weeks of age with H/o ante partum haemorrhage were screened for placenta previa, confirmed by ultra sonography and included in the study. Clinical history, obstetric examination was done and followed up till the delivery. Maternal and foetal outcomes were recorded. Data analyzed by using SPSS version 20.Results: 1.4% incidence of PP was noted, mean age of group was 29.17±1.6 years. Age group of 21-30 years, multiparity Gravida 2-4, previous history of caesarean section and less number of ante natal checkups were significant risk factors and LSCS was most common outcome. Prematurity, low birth weight and APGAR <7 score for 1 minute was common foetal outcomes.Conclusions: Our study strongly suggests foetal surveillance programmes in cases of placenta previa. Measures should be made to bring awareness about PP, in urban slums and to increase medical checkups regularly. Making USG mandatory during every ANC and referral of cases of PP to tertiary care centres would definitely reduce the chances of morbidity and mortality.

Sign in / Sign up

Export Citation Format

Share Document