scholarly journals Rheumatologic manifestations in a cohort of patients with Vogt–Koyanagi–Harada disease

2021 ◽  
Author(s):  
Sinem Burcu Kocaer ◽  
Mahmut Kaya ◽  
Suzan Guven Yilmaz ◽  
Ziya Ayhan ◽  
Ali Osman Saatci ◽  
...  
Keyword(s):  
Current Knowledge ◽  
Autoimmune Disorder ◽  
Inflammatory Back Pain ◽  
Inflammatory Rheumatic Diseases ◽  
X Rays ◽  
Common Features ◽  
Nuclear Antigens ◽  
Pathergy Test ◽  
Rheumatic Conditions ◽  
The Common

ABSTRACT Objectives Vogt–Koyanagi–Harada Disease (VKHD) is a systemic autoimmune disorder characterized by granulomatous panuveitis. Inflammatory rheumatic diseases (IRDs) are among the differential diagnosis of VKHD. However, current knowledge on the rheumatological aspects of VKHD is still limited. We aimed to investigate the prevalence of rheumatic conditions in VKHD patients. Methods VKHD patients were included in the study and they were reviewed in terms of the presence of any rheumatological manifestations. Results There were 18 patients with a female preponderance (83.3%, female). Inflammatory type of peripheral joint pain (11%) and sicca symptoms (33%) were the most common rheumatological findings. The frequency of spondyloarthritis-related features such as inflammatory back pain and HLA-B27 rate was not increased. None of the patients had radiographic sacroiliitis. Anti-nuclear antibody was positive in high titres nearly in 30% of the patients and three patients had antibodies against extractable nuclear antigens. Nailfold capillaroscopy was abnormal in about one-third of the patients. Pathergy test was negative in all cohorts. While angiotensin-converting enzyme was elevated in nearly 20% of the patients, there were no abnormalities on chest X-rays. Conclusion VKHD shares some features with IRDs. The common features were mostly suggestive of connective tissue disease rather than SpA or rheumatoid arthritis.

scholarly journals Lophius in the world: a synthesis on the common features and life strategies

2008 ◽  
Vol 65 (7) ◽  
pp. 1272-1280 ◽  
Author(s):  
A. C. Fariña ◽  
M. Azevedo ◽  
J. Landa ◽  
R. Duarte ◽  
P. Sampedro ◽  
...  
Keyword(s):  
Life Histories ◽  
Current Knowledge ◽  
Northwest Pacific ◽  
Biological Traits ◽  
Life Strategies ◽  
Common Features ◽  
Genetic Structure Of Populations ◽  
The World ◽  
Adaptive Processes ◽  
The Common

Abstract Fariña, A. C., Azevedo, M., Landa, J., Duarte, R., Sampedro, P., Costas, G., Torres, M. A., and Cañás, L. 2008. Lophius in the world: a synthesis on the common features and life strategies. – ICES Journal of Marine Science, 65: 1272–1280. Seven species of Lophius are known worldwide, six in the Atlantic Ocean and just one in the Northwest Pacific. The genus supports valuable fisheries (except for Lophius vaillanti), most for a long time, though the exploitation of Lophiusgastrophysus along the coast of Brazil is relatively recent. The manuscript reviews the current knowledge of phylogeographic and biological traits of Lophius species, pointing out common aspects in the life histories. Within the Lophiidae, the genus Lophius is phylogenetically the most derived, vicariance and dispersal having played a significant role in driving speciation. Life histories seem to have followed similar adaptive processes from a common ancestor along with similar environmental characteristics. The genetic structure of populations is poorly known, and usually, genetic differentiation is limited. Life-history aspects (age, growth, reproductive cycle, early stages, and feeding ecology) are addressed, and fisheries are reviewed. However, knowledge of many aspects of the biology and ecology (e.g. validation of the growth pattern, maturation processes, spawning areas and periodicity, recruitment processes, mortality, stock identification, and habitat needs) remains limited.

scholarly journals Activity of MCPIP1 RNase in tumor associated processes

2019 ◽  
Vol 38 (1) ◽  
Author(s):  
Katarzyna Miekus ◽  
Jerzy Kotlinowski ◽  
Agata Lichawska-Cieslar ◽  
Janusz Rys ◽  
Jolanta Jura
Keyword(s):  
Zinc Finger ◽  
Current Knowledge ◽  
Negative Regulator ◽  
Zinc Finger Domain ◽  
Common Features ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein ◽  
Terminal Domain ◽  
The Common

Abstract The monocyte chemoattractant protein-induced protein (MCPIP) family consists of 4 members (MCPIP1–4) encoded by the ZC3h12A-D genes, which are located at different loci. The common features of MCPIP proteins are the zinc finger domain, consisting of three cysteines and one histidine (CCCH), and the N-terminal domain of the PilT protein (PilT-N-terminal domain (PIN domain)). All family members act as endonucleases controlling the half-life of mRNA and microRNA (miRNA). The best-studied member of this family is MCPIP1 (also known as Regnase-1). In this review, we discuss the current knowledge on the role of MCPIP1 in cancer-related processes. Because the characteristics of MCPIP1 as a fundamental negative regulator of immune processes have been comprehensively described in numerous studies, we focus on the function of MCPIP1 in modulating apoptosis, angiogenesis and metastasis.

Aposematism

2018 ◽  
Author(s):  
Graeme D. Ruxton ◽  
William L. Allen ◽  
Thomas N. Sherratt ◽  
Michael P. Speed
Keyword(s):  
Secondary Effects ◽  
Warning Coloration ◽  
Common Features ◽  
Initial Evolution ◽  
The Common ◽  
Aposematic Signals

Aposematism is the pairing of two kinds of defensive phenotype: an often repellent secondary defence that typically renders prey unprofitable to predators if they attack them and some evolved signal that indicates the presence of that defence. Aposematic signals often work to modify the behaviours of predators both before and during attacks. Warning coloration, for example, may increase wariness and hence improve the chances that a chemically defended prey is released unharmed after an attack. An aposematic signal may therefore first tend to reduce the probability that a predator commences attack (a primary defence) and then (as a component of secondary defence) reduce the probability that the prey is injured or killed during any subsequent attack. In this chapter we will consider both the primary and the secondary effects of aposematic signals on prey protection. We begin first by describing the common features of aposematic signals and attempting to show the wide use to which aposematic signalling is deployed across animals (and perhaps plants too). We then review the interesting evolutionary issues aposematic signals raise, including their initial evolution and their integration with sexual and other signals. We also discuss important ecological, co-evolutionary, and macroevolutionary consequences of aposematism.

A comparison of the changes in the patterns of the usage and categorization of the classifier ‘ben 本’ in Korean, Chinese, and Japanese

2021 ◽  
Vol 5 (1) ◽  
pp. 43-51
Author(s):  
Jeong-A Jo
Keyword(s):  
Cultural Differences ◽  
Chinese Character ◽  
Chinese Characters ◽  
Common Features ◽  
The World ◽  
The Common ◽  
Korean Chinese ◽  
The Relationship

This study aims to examine the common features and differences in how the Chinese-character classifier ‘ ben 本’ is used in Chinese, Korean, and Japanese, and will explore the factors that have affected the categorization processes and patterns of the classifier ‘ ben 本.’ Consideration of the differences in the patterns of usage and categorization of the same Chinese classifier in different languages enables us to look into the perception of the world and the socio cultural differences inherent in each language, the differences in the perception of Chinese characters, and the relationship between classifiers.

scholarly journals Current Knowledge of Endolysosomal and Autophagy Defects in Hereditary Spastic Paraplegia

Cells ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1678
Author(s):  
Liriopé Toupenet Marchesi ◽  
Marion Leblanc ◽  
Giovanni Stevanin
Keyword(s):  
Nervous System ◽  
Motor Neurons ◽  
Neurological Disorders ◽  
Hereditary Spastic Paraplegia ◽  
Current Knowledge ◽  
Spastic Paraplegia ◽  
Functional Convergence ◽  
The Common ◽  
Hsp Genes

Hereditary spastic paraplegia (HSP) refers to a group of neurological disorders involving the degeneration of motor neurons. Due to their clinical and genetic heterogeneity, finding common effective therapeutics is difficult. Therefore, a better understanding of the common pathological mechanisms is necessary. The role of several HSP genes/proteins is linked to the endolysosomal and autophagic pathways, suggesting a functional convergence. Furthermore, impairment of these pathways is particularly interesting since it has been linked to other neurodegenerative diseases, which would suggest that the nervous system is particularly sensitive to the disruption of the endolysosomal and autophagic systems. In this review, we will summarize the involvement of HSP proteins in the endolysosomal and autophagic pathways in order to clarify their functioning and decipher some of the pathological mechanisms leading to HSP.

Addressing common errors and misconceptions in integral calculus with clickers and classroom voting

2019 ◽  
Vol 39 (2) ◽  
pp. 71-85
Author(s):  
Kelly Cline ◽  
Holly Zullo ◽  
David A Huckaby
Keyword(s):  
Correct Answer ◽  
Group Discussion ◽  
Multiple Choice ◽  
Small Group Discussion ◽  
Multiple Choice Questions ◽  
Integral Calculus ◽  
Common Features ◽  
Incorrect Answer ◽  
The Common ◽  
The Mean

Abstract Common student errors and misconceptions can be addressed through the method of classroom voting, in which the instructor presents a multiple-choice question to the class, and after a few minutes for consideration and small-group discussion, each student votes on the correct answer, using a clicker or a phone. If a large number of students have voted for one particular incorrect answer, the instructor can recognize and address the issue. In order to identify multiple-choice questions that are especially effective at provoking common errors and misconceptions, we recorded the percentages of students voting for each option on each question used in 25 sections of integral calculus, taught by 7 instructors, at 4 institutions, over the course of 12 years, on a collection of 172 questions. We restricted our analysis to the 115 questions which were voted on by at least 5 different classes. We present the six questions that caused the largest percentages of students to vote for a particular incorrect answer, discuss how we used these questions in the classroom, and examine the common features of these questions. Further, we look for correlations between question characteristics and the mean percentage of students voting for common errors on these questions, and we find that questions based on general cases have higher percentages of students voting for common errors.

scholarly journals Crystal structure of a new monoclinic polymorph ofN-(4-methylphenyl)-3-nitropyridin-2-amine

2014 ◽  
Vol 70 (8) ◽  
pp. 58-61
Author(s):  
Aina Mardia Akhmad Aznan ◽  
Zanariah Abdullah ◽  
Vannajan Sanghiran Lee ◽  
Edward R. T. Tiekink
Keyword(s):  
Three Dimensional ◽  
Basis Set ◽  
Dihedral Angles ◽  
Asymmetric Unit ◽  
Acta Cryst ◽  
Common Features ◽  
Compound C ◽  
B3lyp Level ◽  
The Common ◽  
Independent Molecules

The title compound, C12H11N3O2, is a second monoclinic polymorph (P21, withZ′ = 4) of the previously reported monoclinic (P21/c, withZ′ = 2) form [Akhmad Aznanet al.(2010).Acta Cryst.E66, o2400]. Four independent molecules comprise the asymmetric unit, which have the common features of asyndisposition of the pyridine N atom and the toluene ring, and an intramolecular amine–nitro N—H...O hydrogen bond. The differences between molecules relate to the dihedral angles between the rings which range from 2.92 (19) to 26.24 (19)°. The geometry-optimized structure [B3LYP level of theory and 6–311 g+(d,p) basis set] has the same features except that the entire molecule is planar. In the crystal, the three-dimensional architecture is consolidated by a combination of C—H...O, C—H...π, nitro-N—O...π and π–π interactions [inter-centroid distances = 3.649 (2)–3.916 (2) Å].

A comparison of the changes in the patterns of the usage and categorization of the classifier ‘ben 本’ in Korean, Chinese, and Japanese

2021 ◽  
pp. 251385022098177
Author(s):  
Jeong-A Jo
Keyword(s):  
Cultural Differences ◽  
Chinese Character ◽  
Chinese Characters ◽  
Common Features ◽  
The World ◽  
The Common ◽  
Korean Chinese ◽  
The Relationship

This study aims to examine the common features and differences in how the Chinese-character classifier ‘ ben 本’ is used in Chinese, Korean, and Japanese, and will explore the factors that have affected the categorization processes and patterns of the classifier ‘ ben 本.’ Consideration of the differences in the patterns of usage and categorization of the same Chinese classifier in different languages enables us to look into the perception of the world and the socio cultural differences inherent in each language, the differences in the perception of Chinese characters, and the relationship between classifiers.

The Latah Reaction: Its Pathodynamics and Nosological Position

1952 ◽  
Vol 98 (413) ◽  
pp. 515-564 ◽  
Author(s):  
P. M. Yap
Keyword(s):  
Nineteenth Century ◽  
Geographical Distribution ◽  
English Literature ◽  
Intrinsic Interest ◽  
Common Features ◽  
Malay Archipelago ◽  
Mental Diseases ◽  
The World ◽  
The Common ◽  
Unusual Symptoms

Few mental diseases have attracted the attention of medical men working in outlandish parts of the world more than Latah. This is due, not only to its intrinsic interest, showing as it regularly does the unusual symptoms of echolalia, echopraxia, and automatic obedience, but also to its remarkable geographical distribution. This illness was described by travellers to the Malay Archipelago in the latter part of the nineteenth century, but very similar reactions were later found to exist in other lands, known to the native peoples by other names. The term “Latah,” however, is the best known, and as the common features between these various reactions became apparent, it has been used as an inclusive name for them all. It is to-day employed with much the same connotation in the French, Dutch, Italian, and English literature, but the discussion of its nature betrays inadequate understanding, attempts at its nosological classification remain unsatisfactory, and speculations as to its aetology continue to be somewhat fanciful.

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