P1303ASSOCIATION BETWEEN PULSE PRESSURE AND EXTRACELLULAR TO INTRACELLULAR WATER RATIO IN HEMODIALYSIS PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Robert Ekart ◽  
Gasper Keber ◽  
Benjamin Dvorsak ◽  
Masa Knehtl ◽  
Radovan Hojs
Keyword(s):  
Blood Pressure ◽  
Body Composition ◽  
Diastolic Blood Pressure ◽  
Pulse Pressure ◽  
Significant Risk ◽  
The Body ◽  
Intracellular Water ◽  
Whole Body ◽  
Multifrequency Bioimpedance ◽  
Dialysis Vintage

Abstract Background and Aims Optimal fluid management is a challenge in patients with end-stage kidney disease (ESRD) on maintenance hemodialysis (HD). Multifrequency bioimpedance spectroscopy (MBIS) is a non-invasive method to estimate body composition, including estimates of extracellular water (ECW) and intracellular water (ICW) and the ratio between both spaces (ECW/ICW). Pulse pressure is a significant risk factor of cardiovascular disease and death in general and dialysis population. Our study aimed to analyse the correlation between systolic, diastolic and pulse pressure with body composition status in ESRD patients before HD. Method We performed a retrospective single-centre cohort study in 93 HD patients. The body composition was measured using the portable whole-body MBIS device, Body Composition Monitor-BCM(®) (Fresenius Medical Care, Bad Homburg, Germany). Blood pressure was measured with OMRON monitors. Results The mean age of patients was 64 ± 13 years, mean dialysis vintage 63 (1-352) months, 61% were men, all patients had arteriovenous fistula as vascular access. Sixty-nine (74.2%) patients were fluid overload (FO) with > 1.1 L overhydration. Other data are presented in table 1. We found a statistically significant correlation between the pulse pressure and ECW/ICW ratio (r=0.258; P=0.033) in FO patients. In contrast, there was no significant correlation between systolic, diastolic blood pressure and ECW/ICW ratio in FO patients. Conclusion Only pulse pressure and not systolic or diastolic blood pressure values measured before HD are associated with ECW/ICW ratio in FO patients.

P1185LUNG COMETS AND EVALUATION OF HYDRATION STATUS IN PERITONEAL DIALYSIS PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Robert Ekart ◽  
Lucijan Lucic Srajer ◽  
Katharina Marko ◽  
Nina Hojs ◽  
Sebastjan Bevc ◽  
...  
Keyword(s):  
Body Composition ◽  
Peritoneal Dialysis ◽  
The Body ◽  
Whole Body ◽  
Fluid Distribution ◽  
Hydration Status ◽  
Non Invasive ◽  
Fluid Status ◽  
Multifrequency Bioimpedance ◽  
Dialysis Vintage

Abstract Background and Aims Assessment of optimal hydration status in patients with end-stage renal disease (ESRD) on peritoneal dialysis (PD) is a challenge. Multiple diagnostic options to determine hydration status in PD patients are available. Multifrequency bioimpedance spectroscopy (MBIS) is a cheap, simple and non-invasive method of estimating body composition, including estimates of total body water (TBW), extracellular water (ECW), intracellular water (ICW) and the ratio between both spaces (ECW/ICW). Lung ultrasonography (LUS) and lung B-lines (lung comets) can be used for the evaluation of extravascular lung water. Ultrasound evaluation of inferior vena cava (UIVC) provides rapid, non-invasive assessment of a patient's hemodynamic and volume status. N-terminal pro-brain natriuretic peptide (NT-proBNP) is related to fluid status and fluid distribution. The aim of our study was to assess fluid status in PD patients comparing four different methods: MBIS, LUS, UIVC and NT-proBNP. Method We performed a single-centre cohort study in 19 PD patients. The body composition was measured using the portable whole-body MBIS device, Body Composition Monitor-BCM(®) (Fresenius Medical Care, Bad Homburg, Germany), LUS with portable US device (VScan, General Electrics Corporate), UIVC index with SonoSite US device. NT-proBNP was measured in a one-step sandwich chemiluminescent immunoassay (Dimension Vista® System 1500, Siemens Healthcare Diagnostics Inc., Newark, NJ, USA). Results The mean age of patients was 54 ± 10 years, mean dialysis vintage 53 (10-194) months, 63% were men. Thirteen (68.4%) patients had fluid overload (FO) > 1.1 L. Data of patients are presented in table 1. We found a statistically significant correlation between the number of lung comets and ECW/ICW ratio (r = 0.496, P = 0.031) and NT-proBNP (r = 0.759, P < 0.0001). In contrast, there was no significant correlation between the number of lung comets and UIVC (r = 0.221, P < 0.364). Conclusion According to our results, LUS with lung comets, MBIS with ECW/ICW ratio and NT-proBNP are useful and complementary methods for evaluation of fluid status in PD patients.

scholarly journals The Influence of Whole-Body Vibration on Cardiovascular Parameters and Changes in the Perception of an External Stimulus in Postmenopausal Women

2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Joanna Witkoś ◽  
Magdalena Hartman-Petrycka
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Body Composition ◽  
Body Weight ◽  
Diastolic Blood Pressure ◽  
Whole Body Vibration ◽  
The Body ◽  
Whole Body ◽  
Sensory Threshold ◽  
Body Vibration

Introduction: Medical science is constantly looking for effective methods to prevent involutional changes. Whole-body vibration training is a promising form of systemic rehabilitation. Aim: The aim of the study was to assess the effect of whole-body vibration on basic cardiovascular parameters (heart rate and blood pressure) and changes in the perception of an external stimulus in postmenopausal women with different body composition. Material and methods: The study was pilot and involved 20 women. Before the procedure, the body composition analysis was performed using the Tanita analyser. All participants underwent a series of vibration massage treatments lasting 30 minutes. Blood pressure, heart rate and sensory threshold levels were measured before and after the vibrotherapy. Results: Diastolic blood pressure before vs. after (median; 74.20 vs. 71.45 mmHg; p=0.047), heart rate before vs. after (median; 67.40 vs. 66.00 bpm; p<0.001). Higher water content positively correlated with a decrease in diastolic blood pressure (R=0.51; p<0.05). The older the woman was, the less the heart rate decreased (R=-0.45; p<0.05). After vibrotherapy, the sensory threshold values in the non-dominant hand decreased slightly (p=0.076). The greater the visceral fat content (R=-0.48; p<0.05) and body weight (R=-0.56; p<0.05), the smaller was the improvement in the threshold. Conclusions: After whole-body vibration, the values of diastolic blood pressure and heart rate in the examined women were lower than those recorded before the procedure. It has been shown that the higher water content in the female body was associated with a greater reduction in diastolic blood pressure. However, the older the woman, the less was the decrease in heart rate. After the whole-body vibrotherapy, only a slight decrease in the sensory threshold was noted. However, it was found that in the studied women the greater the content of visceral fat tissue and the body weight, the smaller the change in sensory sensitivity.

MO730THORACIC BIOIMPEDANCE AS AN INNOVATIVE TOOL TO DETECT CHANGES IN BLOOD PRESSURE DURING HEMODIALYSIS

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Melanie Schoutteten ◽  
Lucas Lindeboom ◽  
Christophe Smeets ◽  
Bart De Moor ◽  
Jacques Peeters ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pearson Correlation ◽  
Extracellular Volume ◽  
The Body ◽  
Whole Body ◽  
P Value ◽  
Predictive Tool ◽  
Low Frequencies ◽  
Dialysis Vintage ◽  
Innovative Tool

Abstract Background and Aims Blood pressure (BP) variability is an important cardiovascular risk factor that contributes to the high burden of cardiovascular mortality in hemodialysis (HD) patients. Ultrafiltration rate (UFR) and plasma refill rate modify the extracellular volume (ECV), which is a major determinant of the systolic BP. Segmental bioimpedance of the thoracic region addresses the central volume compartment of the body. We hypothesize that changes in bioimpedance reflect changes in BP and that thoracic measurements are more accurately in detecting intradialytic BP changes compared to whole body bioimpedance. Method During two consecutive short-term interval HD sessions, thoracic bioimpedance signal was registered continuously from predialysis until the end of the session. Corresponding BP, whole body bioimpedance and ultrafiltration volume (UFV) after the start and at the end of dialysis was registered. After outlier detection, valid raw bioimpedance data [Ohm] at 8 and 160 kHz for thoracic measurements, and 5 and 200 kHz for whole body measurements, were taken into further analysis. Dialysis sessions were divided into 3 groups according to the development of the systolic BP: a drop ≥ than 20 mmHg was defined as a hypotensive session, an increase ≥ 10 mmHg was considered as a hypertensive session. Pearson correlation analysis was applied (r, p-value) to the relative data, calculated as a percentage from the start value. Results From 2 dialysis centres, a total of 46 HD patients were enrolled in the study (65.2% male, mean age 71 ± 12.6 years, mean dialysis vintage 4 ± 3.9 years), which resulted in 89 dialysis sessions to analyse. Mean systolic BP after start of dialysis was 133.2 ± 20.7 mmHg and mean UF volume was 1817.5 ± 801.5 mL. 23 sessions showed a hypotensive gradient from the start till the end of dialysis, and 13 sessions progressed with an increase of more than 10 mmHg. When the 8 kHz curve was plotted according to the 3 BP groups, a more plane increase in thoracic bioimpedance signal was observed in the group with a normal tension course (Figure 1). There was a significant relationship between UFR and changes in relative bioimpedance data, as well as thoracic (r = .49 at 8 kHz, r = .46 at 160 kHz, all ps &lt; .001), as whole body bioimpedance (r = .58 at 5 kHz, r = .52 at 200 kHz, all ps &lt; .001). UFV correlated with changes in systolic BP (r = -.31, p &lt; .01). Both bioimpedance techniques correlated with each other (r = .38, p = .001 for low frequencies; r = .29, p &lt; .01 for high frequencies). Where the relative thoracic bioimpedance signal correlated with changes in systolic BP (r = -.35 at 8kHz, -.32 at 160 kHz, all ps &lt; .01) (Figure 2), whole body did not. Conclusion Thoracic bioimpedance is associated with intradialytic BP changes, whereas whole body bioimpedance is not. Thoracic bioimpedance has the potential to function as an important diagnostic and predictive tool in BP variability during HD.

scholarly journals Comparison of Body Composition Parameters in Swimmers and Non Swimmers: A Cross-sectional Study

2021 ◽  
Author(s):  
Sruthi Parayil Kizhakkevalappil ◽  
Reena Alexander ◽  
Arun Chandran Nhattuvalappil
Keyword(s):  
Blood Pressure ◽  
Body Composition ◽  
Diastolic Blood Pressure ◽  
Cross Sectional Study ◽  
T Test ◽  
The Body ◽  
Fat Free Mass ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional

Introduction: Swimming is an inexpensive isotonic exercise that is useful for health promotion and prevention of disease. While studies based on body composition and swimming in India are few, the analysis of body composition parameters can provide accurate body assessment and serve as an ideal mode for fitness analysis and promotion of health. Aim: To assess the body composition, anthropometric and cardiac parameters of healthy swimmers and compare these variables with that of healthy non swimmers. Materials and Methods: A comparative cross-sectional study was conducted in the Department of Physiology, Government Medical College, Thrissur, Kerala, India. Duration of study was from January 2017 to January 2018. A total 60 healthy individuals, 30 swimmers and 30 non swimmers were selected by simple random sampling method. Body composition parameters were estimated along with anthropometric measurements and cardiac parameters- height, weight, Body Mass Index (BMI), pulse rate, systolic and diastolic blood pressure. Quantitative variables like body composition parameters were analysed using mean standard deviation and 95% confidential interval. Comparison of body composition parameters were analysed using independent t-test and significant level was kept at 5%. Results: The mean age of swimmers was 19.93±1.59 years and that of non swimmer subjects was 22.87±1.88 years. Body composition parameters included Body Fat Percentage (BFP p-value <0.001), Fat Mass (FM p-value <0.001) and Basal Metabolic Rate (BMR p-value <0.001) were found to be significantly decreased (p-value <0.05) in swimmers when compared to non swimmers. However, the Fat Free Mass (FFM p-value=0.13) and Fat Free Mass Index (FFMI p-value=0.22) were also decreased but comparable (p-value >0.05). Weight and BMI along with pulse, systolic blood pressure and diastolic blood pressure (p-value <0.001) were lower in swimmers than non swimmers and statistically significant (p-value <0.05) by independent t-test. Conclusion: The results indicated that, swimming can improve body composition parameters to a more healthy state and therefore can be advised as a form of regular physical activity with a goal to achieve ideal health and fitness.

scholarly journals Biomechanical Aspects of the Foot Arch, Body Balance and Body Weight Composition of Boys Training Football

2021 ◽  
Vol 18 (9) ◽  
pp. 5017
Author(s):  
Joanna M. Bukowska ◽  
Małgorzata Jekiełek ◽  
Dariusz Kruczkowski ◽  
Tadeusz Ambroży ◽  
Jarosław Jaszczur-Nowicki
Keyword(s):  
Body Composition ◽  
Body Height ◽  
Study Groups ◽  
The Body ◽  
Whole Body ◽  
Training Methods ◽  
Training Experience ◽  
Mean Values ◽  
Significance Level ◽  
Body Balance

Background: The aim of the study is to assess the body balance and podological parameters and body composition of young footballers in the context of the control of football training. Methods: The study examined the distribution of the pressure of the part of the foot on the ground, the arch of the foot, and the analysis of the body composition of the boys. The pressure center for both feet and the whole body was also examined. The study involved 90 youth footballers from Olsztyn and Barczewo in three age groups: 8–10 years, 11–13 years old, and 14–16 years. The study used the Inbody 270 body composition analyzer and the EPSR1, a mat that measures the pressure distribution of the feet on the ground. Results: The results showed statistically significant differences in almost every case for each area of the foot between the groups of the examined boys. The most significant differences were observed for the metatarsal area and the left heel. In the case of stabilization of the whole body, statistically significant differences were noted between all study groups. In the case of the body composition parameters, in the examined boys, a coherent direction of changes was noticed for most of them. The relationships and correlations between the examined parameters were also investigated. The significance level in the study was set at p < 0.05. Conclusions: Under the training rigor, a statistically significant increase in stability was observed with age. The total length of the longitudinal arch of both feet of the examined boys showed a tendency to flatten in direct proportion to the age of the examined boys. Mean values of the body composition parameters reflect changes with the ontogenetic development, basic somatic parameters (body height and weight) and training experience, and thus with the intensity and volume of training. This indicates a correct training process that does not interfere with the proper development of the body in terms of tissue and biochemical composition.

What Physical Fitness Component Is Most Closely Associated With Adolescents' Blood Pressure?

2017 ◽  
Vol 124 (6) ◽  
pp. 1107-1120 ◽  
Author(s):  
Heloyse E. G. Nunes ◽  
Carlos A. S. Alves ◽  
Eliane C. A. Gonçalves ◽  
Diego A. S. Silva
Keyword(s):  
Blood Pressure ◽  
Body Composition ◽  
Muscle Strength ◽  
Physical Fitness ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Aerobic Fitness ◽  
Pressure Control ◽  
Cross Sectional ◽  
Digital Pressure

This study aimed to determine which of four selected physical fitness variables, would be most associated with blood pressure changes (systolic and diastolic) in a large sample of adolescents. This was a descriptive and cross-sectional, epidemiological study of 1,117 adolescents aged 14–19 years from southern Brazil. Systolic and diastolic blood pressure were measured by a digital pressure device, and the selected physical fitness variables were body composition (body mass index), flexibility (sit-and-reach test), muscle strength/resistance (manual dynamometer), and aerobic fitness (Modified Canadian Aerobic Fitness Test). Simple and multiple linear regression analyses revealed that aerobic fitness and muscle strength/resistance best explained variations in systolic blood pressure for boys (17.3% and 7.4% of variance) and girls (7.4% of variance). Aerobic fitness, body composition, and muscle strength/resistance are all important indicators of blood pressure control, but aerobic fitness was a stronger predictor of systolic blood pressure in boys and of diastolic blood pressure in both sexes.

scholarly journals Follow-up of GK rats during prediabetes highlights increased insulin action and fat deposition despite low insulin secretion

2008 ◽  
Vol 294 (1) ◽  
pp. E168-E175 ◽  
Author(s):  
Jamileh Movassat ◽  
Danièle Bailbé ◽  
Cécile Lubrano-Berthelier ◽  
Françoise Picarel-Blanchot ◽  
Eric Bertin ◽  
...  
Keyword(s):  
Body Composition ◽  
Insulin Secretion ◽  
Insulin Sensitivity ◽  
Cell Function ◽  
Cell Mass ◽  
The Body ◽  
Whole Body ◽  
Β Cell ◽  
Gk Rats

The adult Goto-Kakizaki (GK) rat is characterized by impaired glucose-induced insulin secretion in vivo and in vitro, decreased β-cell mass, decreased insulin sensitivity in the liver, and moderate insulin resistance in muscles and adipose tissue. GK rats do not exhibit basal hyperglycemia during the first 3 wk after birth and therefore could be considered prediabetic during this period. Our aim was to identify the initial pathophysiological changes occurring during the prediabetes period in this model of type 2 diabetes (T2DM). To address this, we investigated β-cell function, insulin sensitivity, and body composition in normoglycemic prediabetic GK rats. Our results revealed that the in vivo secretory response of GK β-cells to glucose is markedly reduced and the whole body insulin sensitivity is increased in the prediabetic GK rats in vivo. Moreover, the body composition of suckling GK rats is altered compared with age-matched Wistar rats, with an increase of the number of adipocytes before weaning despite a decreased body weight and lean mass in the GK rats. None of these changes appeared to be due to the postnatal nutritional environment of GK pups as demonstrated by cross-fostering GK pups with nondiabetic Wistar dams. In conclusion, in the GK model of T2DM, β-cell dysfunction associated with increased insulin sensitivity and the alteration of body composition are proximal events that might contribute to the establishment of overt diabetes in adult GK rats.

Effects of Aging on the Variability of Arterial Pressure in Essential Hypertensive Patients

1982 ◽  
Vol 63 (s8) ◽  
pp. 411s-414s ◽  
Author(s):  
Jun Ogawa ◽  
Shigeo Takata ◽  
Gakuji Nomura ◽  
Shiro Arai ◽  
Takayuki Ikeda ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Stroke Volume ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Pulse Pressure ◽  
Baroreflex Sensitivity ◽  
Peripheral Resistance ◽  
Resistance Index ◽  
Average Systolic Blood Pressure ◽  
Effects Of Aging

1. We studied the effects of aging on the variability of blood pressure in mild to moderate essential hypertensive subjects. 2. Cardiac index was greater and total peripheral resistance index was less in patients under 40 years (by an average of 1.06 litres min−1 m−2 and 9.23 mmHg 1−1 min−1 m−2) than in those over 40 respectively (P < 0.001 for each). 3. Pulse pressure/stroke volume was less by an average of 0.345 mmHg/ml in patients under 40 years than that in those over 40 (P < 0.001). Pulse pressure/stroke volume was correlated with age (r = 0.621), average systolic blood pressure (r = 0.623) and inversely with baroreflex sensitivity (r = −0.494). 4. Baroreflex sensitivity was less by an average of 3.1 ms/mmHg in patients over 30 years than in those under 30 (P < 0.025). Baroreflex sensitivity was inversely correlated with age (r = −0.617) and average systolic blood pressure (r = −0.589). 5. Beat by beat variability of systolic blood pressure was correlated with age (r = 0.460), particularly when the data of those in their twenties were excluded (r = 0.618), and significantly with pulse pressure/stroke volume (r = 0.650), average systolic blood pressure (r = 0.618) and inversely with baroreflex sensitivity (r = −0.477). These relationships were not observed for diastolic blood pressure. 6. Maximum difference in systolic blood pressure in a day was correlated with pulse pressure/stroke volume (r = 0.482) and average systolic blood pressure (r = 0.648) but not with baroreflex sensitivity. These relationships were not observed for diastolic blood pressure. 7. Variability of systolic blood pressure in patients over 30 years gradually increased with age. In contrast, those of systolic and diastolic blood pressures in subjects in their twenties were relatively large. This might be related to factors other than aging, presumably those which underlie the hyperdynamic circulatory state.

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