scholarly journals Resistin and all-cause and cardiovascular mortality: effect modification by adiponectin in end-stage kidney disease patients

2013 ◽  
Vol 28 (suppl 4) ◽  
pp. iv181-iv187 ◽  
Author(s):  
B. Spoto ◽  
F. Mattace-Raso ◽  
E. Sijbrands ◽  
P. Pizzini ◽  
S. Cutrupi ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Cardiovascular Mortality ◽  
Effect Modification ◽  
End Stage Kidney Disease ◽  
Mortality Effect ◽  
End Stage

Cardiovascular mortality in children and young adults with end-stage kidney disease

2002 ◽  
Vol 141 (2) ◽  
pp. 191-197 ◽  
Author(s):  
R.S. Parekh ◽  
C.E. Carroll ◽  
R.A. Wolfe ◽  
F.K. Port
Keyword(s):  
Young Adults ◽  
Kidney Disease ◽  
Cardiovascular Mortality ◽  
End Stage Kidney Disease ◽  
Children And Young Adults ◽  
End Stage

Eccentric Left Ventricular Hypertrophy and Sudden Death in Patients with End-Stage Kidney Disease

2015 ◽  
Vol 42 (2) ◽  
pp. 126-133 ◽  
Author(s):  
Camiel L.M. de Roij van Zuijdewijn ◽  
Romy Hansildaar ◽  
Michiel L. Bots ◽  
Peter J. Blankestijn ◽  
Marinus A. van den Dorpel ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Sudden Death ◽  
Left Ventricular Hypertrophy ◽  
Cardiovascular Mortality ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Convective Transport ◽  
End Stage Kidney Disease ◽  
All Cause Mortality ◽  
End Stage

Background/Aims: Both all-cause and cardiovascular mortality risks are extremely high in patients with end-stage kidney disease (ESKD). Sudden death accounts for approximately one-quarter of all fatal events. Left ventricular hypertrophy (LVH) is a known risk factor for mortality and can be divided in 2 types: concentric and eccentric. This study evaluated possible differences in all-cause mortality, cardiovascular mortality and sudden death between prevalent ESKD patients with concentric and eccentric LVH. Methods: Participants of the CONvective TRAnsport STudy (CONTRAST) who underwent transthoracic echocardiography (TTE) at baseline were analyzed. In patients with LVH, a relative wall thickness of ≤0.42 was considered eccentric and >0.42 was considered concentric hypertrophy. Cox proportional hazards models, adjusted for potential confounders, were used to calculate hazard ratios (HRs) of patients with eccentric LVH versus patients with concentric LVH for all-cause mortality, cardiovascular mortality and sudden death. Results: TTE was performed in 328 CONTRAST participants. LVH was present in 233 participants (71%), of which 87 (37%) had concentric LVH and 146 (63%) eccentric LVH. The HR for all-cause mortality of eccentric versus concentric LVH was 1.14 (p = 0.52), 1.79 (p = 0.12) for cardiovascular mortality and 4.23 (p = 0.02) for sudden death in crude analyses. Propensity score-corrected HR for sudden death in patients with eccentric LVH versus those with concentric LVH was 5.22 (p = 0.03). Conclusions: (1) The hazard for all-cause mortality, cardiovascular mortality and sudden death is markedly increased in patients with LVH. (2) The sudden death risk is significantly higher in ESKD patients with eccentric LVH compared to subjects with concentric LVH.

scholarly journals Association between physical activity and mortality in end-stage kidney disease: a systematic review of observational studies

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Pedro Martins ◽  
Elisa A. Marques ◽  
Diogo V. Leal ◽  
Aníbal Ferreira ◽  
Kenneth R Wilund ◽  
...  
Keyword(s):  
Physical Activity ◽  
Peritoneal Dialysis ◽  
Kidney Disease ◽  
Kidney Transplant ◽  
Cardiovascular Mortality ◽  
Observational Studies ◽  
End Stage Kidney Disease ◽  
Hand Search ◽  
All Cause Mortality ◽  
End Stage

Abstract Background End-stage Kidney Disease patients have a high mortality and hospitalization risk. The association of these outcomes with physical activity is described in the general population and in other chronic diseases. However, few studies examining this association have been completed in end-stage Kidney Disease patients, raising the need to systematically review the evidence on the association of physical activity with mortality and hospitalization in this population. Methods Electronic databases (EBSCO, Scopus and Web of Science) and hand search were performed until March 2020 for observational studies reporting the association of physical activity with mortality or hospitalization in adult end-stage Kidney Disease patients on renal replacement therapy (hemodialysis, peritoneal dialysis and kidney transplant). Methodological quality of the included studies was assessed using the Quality in Prognosis Studies tool. The review protocol was registered in PROSPERO (CRD42020155591). Results Eleven studies were included: six in hemodialysis, three in kidney transplant, and two in hemodialysis and peritoneal dialysis patients. Physical activity was self-reported, except in one study that used accelerometers. All-cause mortality was addressed in all studies and cardiovascular mortality in three studies. Nine studies reported a significant reduction in all-cause mortality with increased levels of physical activity. Evidence of a dose-response relationship was found. For cardiovascular mortality, a significant reduction was observed in two of the three studies. Only one study investigated the association of physical activity with hospitalization. Conclusions Higher physical activity was associated with reduced mortality in end-stage Kidney Disease patients. Future studies using objective physical activity measures could strengthen these findings. The association of physical activity with hospitalization should be explored in future investigations.

Correlations between dental assistance/oral health and clinical intercurrences in an end-stage kidney disease patients: a historical cohort study

2020 ◽  
Vol 69 (2) ◽  
Author(s):  
Sandra M. Assante ◽  
Susana Morimoto ◽  
Tamara K. Tedesco ◽  
Thais Gimenez ◽  
Karen M. Ramalho
Keyword(s):  
Cohort Study ◽  
Oral Health ◽  
Kidney Disease ◽  
End Stage Kidney Disease ◽  
Historical Cohort ◽  
Historical Cohort Study ◽  
End Stage

Impaired Vitamin D Signaling Is Associated With Frequent Development of Renal Cell Tumor in End-stage Kidney Disease

2020 ◽  
Vol 40 (11) ◽  
pp. 6525-6530
Author(s):  
JANOS DOCS ◽  
DANIEL BANYAI ◽  
TIBOR FLASKO ◽  
ARPAD SZANTO ◽  
GYULA KOVACS
Keyword(s):  
Vitamin D ◽  
Kidney Disease ◽  
Renal Cell ◽  
Cell Tumor ◽  
End Stage Kidney Disease ◽  
Vitamin D Signaling ◽  
End Stage

scholarly journals Cardiopulmonary exercise testing (CPET) in patients with end-stage kidney disease (ESKD): principles, methodology and clinical applications of the optimal tool for exercise tolerance evaluation

2021 ◽  
Author(s):  
Eva Pella ◽  
Afroditi Boutou ◽  
Aristi Boulmpou ◽  
Christodoulos E Papadopoulos ◽  
Aikaterini Papagianni ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Exercise Testing ◽  
Cardiopulmonary Exercise Testing ◽  
Exercise Intolerance ◽  
End Stage Kidney Disease ◽  
Exercise Limitation ◽  
Cardiopulmonary Exercise ◽  
Functional Reserves ◽  
Increased Risk ◽  
End Stage

Abstract Chronic kidney disease (CKD), especially end-stage kidney disease (ESKD), is associated with increased risk for cardiovascular events and all-cause mortality. Exercise intolerance as well as reduced cardiovascular reserve are extremely common in patients with CKD. Cardiopulmonary exercise testing (CPET) is a non-invasive, dynamic technique that provides an integrative evaluation of cardiovascular, pulmonary, neuropsychological and metabolic function during maximal or submaximal exercise, allowing the evaluation of functional reserves of these systems. This assessment is based on the principle that system failure typically occurs when the system is under stress and, thus, CPET is currently considered to be the gold-standard for identifying exercise limitation and differentiating its causes. It has been widely used in several medical fields for risk stratification, clinical evaluation and other applications but its use in everyday practice for CKD patients is scarce. This article describes the basic principles and methodology of CPET and provides an overview of important studies that utilized CPET in patients with ESKD, in an effort to increase awareness of CPET capabilities among practicing nephrologists.

Psychosocial factors affecting patients with end-stage kidney disease and the impact of the social worker

2021 ◽  
Author(s):  
Micaella Sotera Hansen ◽  
Wubshet Tesfaye ◽  
Beena Sewlal ◽  
Bharati Mehta ◽  
Kamal Sud ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Psychosocial Factors ◽  
Social Worker ◽  
End Stage Kidney Disease ◽  
Factors Affecting ◽  
The Social ◽  
End Stage ◽  
The Impact
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