Conclusion

Author(s):  
Matthew S. Seligmann

As this book has shown the common conception that ‘Churchill’s “radical phase” was cast to the winds’ when he was put in charge of the Navy in October 1911, although well established in the literature, is not, in fact, accurate.1 The radical President of the Board of Trade, eager to improve the lives of the poor, became the radical Home Secretary, no less enthusiastic for social reform, who then became the radical First Lord of the Admiralty, imbued with both a desire and, perhaps more importantly, a will to intervene in order to better conditions for those who served in the Royal Navy. Accordingly, he embarked upon a major programme of improvement across a wide range of different areas all of which affected the everyday life of sailors. Alcohol intake, sexual behaviour, religious practice, corporal punishment, as well as pay and equality of progression, all came under the spotlight while Churchill was First Lord. Of course, not all of the new measures were successful and not all were progressive in the modern understanding of the term, but all of them represented significant attempts to push forward a radical agenda for change....

Author(s):  
Matthew S. Seligmann

There is an old story about Winston Churchill, which relates that, during his time as First Lord of the Admiralty, he made a proposal for reform that was strenuously opposed by the naval officers around him. The reason given was that Churchill’s measure was not in accord with naval tradition. Hearing this objection, Churchill immediately retorted, ‘Naval tradition? Naval tradition? Monstrous. Nothing but rum, sodomy, prayers and the lash.’ The quotation is frequently dismissed as apocryphal or a jest, but, interestingly, all four areas of naval life singled out were subject to major reform initiatives while Churchill was in charge of the Royal Navy between October 1911 and May 1915. During this period, not only were there major improvements in pay and conditions for sailors, but detailed consideration was given to the future of the spirit ration; to the punishing and eradicating of homosexual practices; to the spiritual concerns of the fleet; and also to the regime of corporal punishment that underpinned naval discipline for boy sailors. In short, under Churchill, the Royal Navy introduced a social reform programme perfectly encapsulated in this elegant quip. And, yet, not only has no one studied it; many people do not even know that such a programme even existed. This book rectifies that. It shows that Churchill was not just a major architect of welfare reform as President of the Board of Trade and as Home Secretary, but that he continued to push a radical social agenda while running the Navy.


Alloy Digest ◽  
1976 ◽  
Vol 25 (2) ◽  

Abstract Copper Alloy No. 268 is a copper-zinc alloy with excellent cold-working properties and good resistance to corrosion. It can be cold worked by all the common fabrication processes and has a wide range of applications. This datasheet provides information on composition, physical properties, hardness, elasticity, tensile properties, and shear strength as well as fatigue. It also includes information on corrosion resistance as well as forming, heat treating, machining, and joining. Filing Code: Cu-306. Producer or source: Brass mills.


Author(s):  
John Toye

After the upheavals of the French Revolution, Enlightenment thinkers were blamed for loosening the bonds of society. In nineteenth-century France, Saint-Simon advocated a social compromise whereby scientists and artists planned the path of progress while the propertied classes retained political power albeit acting as trustees for the interests of the poor. Comte called for a scientific sociology to inform the design of political institutions. In Britain, Bentham rejected the doctrine of natural rights in favour of the principle of utility, while J. S. Mill flirted with Comte’s positivism briefly. Marx made little impact and socialism came in the guise of Fabianism and middle-class trusteeship for the poor. In Germany, Hegel interpreted the French Revolution as a phase in a moral struggle for freedom and called for freedom to be reconciled with the idea of the common good embodied in the state. List envisaged the common good as protectionist trade policy.


Author(s):  
Samuel K. Cohn, Jr.

By exploring the wide range of names given to the ‘new’ sexually transmitted disease—the Great Pox—this chapter dispels notions held for two centuries or more. Instead, no tit-for-tat-naming war among nations accused of carrying the disease ensued. The ‘French disease’ alone became standard in medical texts, but not among commoners and not after the late sixteenth century for physicians. The chapter challenges a second truism of the historiography: that naming meant blaming. Although the disease was named after the French, no laws or pogroms ensued against them or any other ‘other’. However, physicians increasingly identified humans as the essential carriers of this new disease and became concerned with tracking human contacts. By the end of the sixteenth century, medical texts had renamed it the territorially neutral lues venerea. Coincidently, with the rise of this new name, blame placed on women, the poor, and victims of the disease increased.


Author(s):  
Pete Dale

Numerous claims have been made by a wide range of commentators that punk is somehow “a folk music” of some kind. Doubtless there are several continuities. Indeed, both tend to encourage amateur music-making, both often have affiliations with the Left, and both emerge at least partly from a collective/anti-competitive approach to music-making. However, there are also significant tensions between punk and folk as ideas/ideals and as applied in practice. Most obviously, punk makes claims to a “year zero” creativity (despite inevitably offering re-presentation of at least some existing elements in every instance), whereas folk music is supposed to carry forward a tradition (which, thankfully, is more recognized in recent decades as a subject-to-change “living tradition” than was the case in folk’s more purist periods). Politically, meanwhile, postwar folk has tended more toward a socialist and/or Marxist orientation, both in the US and UK, whereas punk has at least rhetorically claimed to be in favor of “anarchy” (in the UK, in particular). Collective creativity and competitive tendencies also differ between the two (perceived) genre areas. Although the folk scene’s “floor singer” tradition offers a dispersal of expressive opportunity comparable in some ways to the “anyone can do it” idea that gets associated with punk, the creative expectation of the individual within the group differs between the two. Punk has some similarities to folk, then, but there are tensions, too, and these are well worth examining if one is serious about testing out the common claim, in both folk and punk, that “anyone can do it.”


2021 ◽  
Vol 22 (9) ◽  
pp. 4626
Author(s):  
Clément Barbereau ◽  
Nicolas Cubedo ◽  
Tangui Maurice ◽  
Mireille Rossel

Tauopathies represent a vast family of neurodegenerative diseases, the most well-known of which is Alzheimer’s disease. The symptoms observed in patients include cognitive deficits and locomotor problems and can lead ultimately to dementia. The common point found in all these pathologies is the accumulation in neural and/or glial cells of abnormal forms of Tau protein, leading to its aggregation and neurofibrillary tangles. Zebrafish transgenic models have been generated with different overexpression strategies of human Tau protein. These transgenic lines have made it possible to highlight Tau interacting factors or factors which may limit the neurotoxicity induced by mutations and hyperphosphorylation of the Tau protein in neurons. Several studies have tested neuroprotective pharmacological approaches. On few-days-old larvae, modulation of various signaling or degradation pathways reversed the deleterious effects of Tau mutations, mainly hTauP301L and hTauA152T. Live imaging and live tracking techniques as well as behavioral follow-up enable the analysis of the wide range of Tau-related phenotypes from synaptic loss to cognitive functional consequences.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Blazej Slazak ◽  
Klara Kaltenböck ◽  
Karin Steffen ◽  
Martyna Rogala ◽  
Priscila Rodríguez-Rodríguez ◽  
...  

AbstractCyclotides are cyclic peptides produced by plants. Due to their insecticidal properties, they are thought to be involved in host defense. Violets produce complex mixtures of cyclotides, that are characteristic for each species and variable in different environments. Herein, we utilized mass spectrometry (LC–MS, MALDI-MS), transcriptomics and biological assays to investigate the diversity, differences in cyclotide expression based on species and different environment, and antimicrobial activity of cyclotides found in violets from the Canary Islands. A wide range of different habitats can be found on these islands, from subtropical forests to dry volcano peaks at high altitudes. The islands are inhabited by the endemic Viola palmensis, V. cheiranthifolia, V. anagae and the common V. odorata. The number of cyclotides produced by a given species varied in plants from different environments. The highest diversity was noted in V. anagae which resides in subtropical forest and the lowest in V. cheiranthifolia from the Teide volcano. Transcriptome sequencing and LC–MS were used to identify 23 cyclotide sequences from V. anagae. Cyclotide extracts exhibited antifungal activities with the lowest minimal inhibitory concentrations noted for V. anagae (15.62 μg/ml against Fusarium culmorum). The analysis of the relative abundance of 30 selected cyclotides revealed patterns characteristic to both species and populations, which can be the result of genetic variability or environmental conditions in different habitats. The current study exemplifies how plants tailor their host defense peptides for various habitats, and the usefulness of cyclotides as markers for chemosystematics.


2021 ◽  
pp. 104063872110245
Author(s):  
Sabri A. Rahman ◽  
Kuan H. Khor ◽  
Siti Khairani-Bejo ◽  
Seng F. Lau ◽  
Mazlina Mazlan ◽  
...  

Leptospirosis is a serious bacterial disease that affects both humans and animals. A wide range of symptoms have been described in humans; the disease in dogs is commonly associated with kidney and/or liver disease. In Malaysia, information about the common serovars infecting dogs is limited. Therefore, we investigated the occurrences of leptospirosis in 124 pet dogs diagnosed with kidney and/or liver disease. Blood, urine, abdominal effusion, and/or kidney and liver were collected from the dogs. Based on microscopic agglutination testing, 53 of 124 (42.7%) dogs were seropositive for leptospiral exposure. Sera were frequently positive to serovars Bataviae ( n = 12), Javanica ( n = 10), and Icterohaemorrhagiae ( n = 10). Direct detection using PCR showed that 42 of 124 (33.9%) of the whole blood and 36 of 113 (31.9%) urine samples were positive for pathogenic Leptospira spp. By PCR, 2 of 23 (9.1%) kidney and 2 of 23 (9.1%) liver were positive for pathogenic Leptospira spp. Abdominal effusion from 4 dogs were PCR-positive for pathogenic Leptospira spp. The species detected were L. interrogans, L. borgpetersenii, L. kirschneri, and L. kmetyi by partial 16S rRNA sequencing. We further identified and characterized 11 Leptospira spp. isolates from 8 dogs as serovars Bataviae, Javanica, and Australis. The mortality rate of the Leptospira-infected dogs was high (18 of 53; 34%).


1999 ◽  
Vol 6 (2) ◽  
pp. 224-271 ◽  
Author(s):  
Khaled Fahmy

AbstractThe reform of the Egyptian criminal justice system in the nineteenth century traditionally has been viewed as forming an important step in the establishment of a liberal and just rule of law. By studying how forensic medicine was introduced into nineteenth-century Egypt, I argue that the need to exercise better control over the population and to monitor crime lay behind the reform process as much as liberal ideas borrowed from Europe did. Drawing on a wide range of archival material, both legal and medical, I analyze the role played by autopsy in the criminal system and argue that the practice of autopsy was viewed differentially by 'ulamā', by Arabic-speaking, French-educated doctors and by the mostly illiterate masses. And contrary to the common wisdom, I conclude that the "modernization" of the Egyptian legal system was intended not to displace the sharīa but to support it.


Oryx ◽  
1998 ◽  
Vol 32 (1) ◽  
pp. 59-67 ◽  
Author(s):  
R. J. Timmins ◽  
T. D. Evans ◽  
Khamkhoun Khounboline ◽  
Chainoi Sisomphone

The large-antlered, or giant, muntjac Megamuntiacus vuquangensis wasdescribed from Vietnam in 1994 and found concurrently in the Annamite Mountains and nearby hill ranges of central and southern Laos. The northerly and southerly range limits are still unknown. It may occupy a wide range of habitats and is found sympatrically with the common muntjac Muntiacus muntjak. Another muntjac species, the taxonomic affinity of which is as yet undetermined, was recently discovered to occur within its range. The large-antlered muntjac is probably not threatened with extinction in the near future, but in view of its restricted range and threats from habitat degradation and hunting, it should be classified as Vulnerable in the Red Data Book. Its future in Laos is largely dependent on the recently created protected-areas system to maintain large tracts of habitat and reduce hunting pressure.


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