Slab Avalanche Release: Data and Field Experiments

2020 ◽  
pp. 25-35
Author(s):  
Francois Louchet
Keyword(s):  
Large Scale ◽  
Field Experiments ◽  
Power Laws ◽  
Recurrence Time ◽  
Recurrence Times ◽  
Elastic Bending ◽  
Release Data ◽  
Statistical Laws

Starting zone sizes are shown to obey statistical laws, named “power laws”, stating that the recurrence time of an event of a given size increases in a precise proportion with its size. Extrapolation of such laws fitted on small-sized events allows a determination of recurrence times for big and uncommon events. The key role of the weak layer (WL) failure is illustrated by “Propagation Saw Tests” (PST), showing that the collapse of a WL zone of a few decimeters may act as a switch, triggering a very large scale spontaneous WL failure. However, the consequences of such a collapse may be damped down by sintering of broken WL grains. We analyze bridging indexes, often used to estimate WL resistance to collapse under loading. We define a new bridging index, extending the usual one to the case of elastic bending, and we discuss the validity domains of both of them.

Ruolo dell'ER e del PSA nello screening per la diagnosi precoce del carcinoma prostatico: The role of ER and PSA in screening for early diagnosis of prostatic carcinoma

1995 ◽  
Vol 62 (2) ◽  
pp. 300-304
Author(s):  
M. Fini ◽  
G. Vagliani
Keyword(s):  
Early Diagnosis ◽  
Large Scale ◽  
Prostatic Carcinoma ◽  
Early Stage ◽  
Time Required ◽  
Oncological Screening ◽  
Sensitivity Specificity ◽  
Diagnosi Precoce

From September 1992 to February 1994, 1441 men aged between 50 and 70 years underwent screening with PSA and ER measurement for early diagnosis of prostatic carcinoma. A neoplasm was diagnosed in 1.73% (25/1441) of cases, which being found at an early stage, made it possible to perform prostatectomy and radical radiotherapy on 37.5% and 16.6% of patients respectively. The incidence of the disease was higher than in a previous screening with just ER dosage (1.73% vs 1.1%). Combined PSA and ER also gave higher sensitivity, specificity, overall accuracy and predictiveness compared to the methods taken individually. This combination seems preferable, in view of the greater efficacy and “practicability” compared to protocols which involve the use of USTR, which is less practicable on a large scale due to the length of time required and high costs. The utility of periodic determination of PSA levels in those over fifty years old is emphasised, both for oncological screening controls and to increase the diagnostic accuracy of other clinical tests.

Looking Backward to Move Forward

2017 ◽  
Vol 43 (4) ◽  
pp. 555-569 ◽  
Author(s):  
Boaz Hameiri ◽  
Arie Nadler
Keyword(s):  
Large Scale ◽  
Field Experiments ◽  
Emotional Needs ◽  
Palestinian Authority ◽  
Mediating Role ◽  
Right Of Return ◽  
Group Members ◽  
The Right ◽  
High Level

Two large-scale surveys conducted in Israel (Study 1A) and the Palestinian Authority (Study 1B) show that the belief by group members that people in the “enemy” group acknowledge their victimhood (i.e., Holocaust and Nakba for Jews and Palestinians, respectively) is associated with Israeli-Jews’ readiness to accept responsibility for Palestinian sufferings and offer apologies. For Palestinians, this belief is linked to a perceived higher likelihood of a reconciled future with Israelis. Three field experiments demonstrate that a manipulated high level of acknowledgment of Jewish victimhood by Palestinians (Studies 2 and 4) and of Palestinian victimhood by Israeli-Jews (Study 3) caused greater readiness to make concessions for the sake of peace on divisive issues (e.g., Jerusalem, the 1967 borders, the right of return) and increased conciliatory attitudes. Additional analyses indicate the mediating role of increased trust and reduced emotional needs in these relationships.

scholarly journals Saliva—Friend and Foe in the COVID-19 Outbreak

Diagnostics ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 290 ◽  
Author(s):  
Pingping Han ◽  
Sašo Ivanovski
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Large Scale ◽  
Immune Status ◽  
Viral Transmission ◽  
Control Measures ◽  
The Novel ◽  
Non Invasive ◽  
Asymptomatic Patients

The coronavirus disease 2019 (COVID-19) outbreak, caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global ongoing pandemic. Timely, accurate and non-invasive SARS-CoV-2 detection in both symptomatic and asymptomatic patients, as well as determination of their immune status, will facilitate effective large-scale pandemic control measures to prevent the spread of COVID-19. Saliva is a biofluid whose anatomical source and location is of particularly strategic relevance to COVID-19 transmission and monitoring. This review focuses on the role of saliva as both a foe (a common mode of viral transmission via salivary droplets and potentially aerosols) and a friend (as a non-invasive diagnostic tool for viral detection and immune status surveillance) in combating COVID-19.

Integrating vehicle tracking and routing systems in retail distribution management

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Loay Salhieh ◽  
Mohammad Shehadeh ◽  
Ismail Abushaikha ◽  
Neil Towers
Keyword(s):  
Field Experiment ◽  
Large Scale ◽  
Field Experiments ◽  
Experimental Treatment ◽  
Capital Budgeting ◽  
Vehicle Tracking ◽  
Content Type ◽  
Study Results ◽  
Distribution Operations

PurposeThe purpose of this paper is to assess the benefits of integrating IT tracking and routing systems into last-mile distribution operations. The paper also demonstrates the role of field experiments as a valid approach for improving the rigour of logistics research.Design/methodology/approachThe study employs a field experiment approach. Data were collected before and after the experimental treatment from 16 participating vehicles, which were used as inputs and outputs to calculate vehicles' efficiencies using data envelopment analysis.FindingsThrough employing manipulation and random assignment to investigate causality in naturally occurring contexts, the study results show statistical evidence for the role of vehicle tracking and routing systems in enhancing fleet efficiency. Furthermore, results show that field experiment is an appropriate method for capital budgeting of deploying IT systems in the distribution function.Practical implicationsDistribution managers can use a field experiment setup to assess the potential impact of installing IT solutions prior to large-scale implementation or prior to purchasing.Originality/valueThe study fills a gap in the literature through the application of a field experiment approach to establish causality relationships in distribution and logistics research. This study should encourage new research on the role of field experimentation in evaluating the benefits gained from, and the capital budgeting of, the modern disruptive technologies in supply chains.

scholarly journals Peran Orang Tua dalam Proses Pembelajaran Pendidikan Agama Islam di Masa Pandemi Covid-19

2021 ◽  
Vol 12 (1) ◽  
pp. 150-157
Author(s):  
Ach. Syaikhu
Keyword(s):  
Religious Education ◽  
Learning Process ◽  
Large Scale ◽  
Task Force ◽  
Education Sector ◽  
Indonesian Government ◽  
The Republic ◽  
Role Of Parents

The Covid-19 pandemic has not ended until today. The spread of this virus give major impact, one of which is the necessity of a regional quarantine policy. In suppressing the number of the spread of covid-19, the Indonesian government has implemented a regional quarantine system (Lockdown) and PSBB (Large-Scale Social Restrictions) in line with the Decree of the Presidential Regulation of the Republic of Indonesia Number 99 of 2020 for the DKI Jakarta area and the Decree of the Minister of Health of Republic Indonesia Number HK.01.07/Menkes/248/2020  concerning the Determination of PSBB in Several Areas of West Java Province (Task Force for Handling COVID-19, 2020). This has an impact on various sectors of life, one of which is the education sector. The role of parents during the Pandemic has increased by supervising and accompanying children in the learning process. In this paper, the author wants to explain the role of parents in assisting the learning process of Islamic Religious Education in children during the Covid-19 pandemic.

Large-scale Motion of Solar Filaments

2000 ◽  
Vol 179 ◽  
pp. 205-208
Author(s):  
Pavel Ambrož ◽  
Alfred Schroll
Keyword(s):  
Magnetic Flux ◽  
Proper Motion ◽  
Time Scale ◽  
Large Scale ◽  
Accuracy Of Measurements ◽  
Solar Filaments ◽  
General Movement ◽  
Scale Motion ◽  
Velocity Scatter

AbstractPrecise measurements of heliographic position of solar filaments were used for determination of the proper motion of solar filaments on the time-scale of days. The filaments have a tendency to make a shaking or waving of the external structure and to make a general movement of whole filament body, coinciding with the transport of the magnetic flux in the photosphere. The velocity scatter of individual measured points is about one order higher than the accuracy of measurements.

The Role of Sense of Direction and Other Factors During Navigation in a Large-Scale, Unconstrained Environment

2013 ◽  
Author(s):  
Elisabeth J. Ploran ◽  
Ericka Rovira ◽  
James C. Thompson ◽  
Raja Parasuraman
Keyword(s):  
Large Scale ◽  
Sense Of Direction

A Molecular Approach to Immunoscintigraphy: A Study of the T-Antigen Conformation on the Surface of Tumors

1987 ◽  
Vol 26 (01) ◽  
pp. 1-6 ◽  
Author(s):  
S. Selvaraj ◽  
M. R. Suresh ◽  
G. McLean ◽  
D. Willans ◽  
C. Turner ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Tumor Cell ◽  
T Antigen ◽  
Human Carcinomas ◽  
Animal Tumor ◽  
Synthetic Antigens

The role of glycoconjugates in tumor cell differentiation has been well documented. We have examined the expression of the two anomers of the Thomsen-Friedenreich antigen on the surface of human, canine and murine tumor cell membranes both in vitro and in vivo. This has been accomplished through the synthesis of the disaccharide terminal residues in both a and ß configuration. Both entities were used to generate murine monoclonal antibodies which recognized the carbohydrate determinants. The determination of fine specificities of these antibodies was effected by means of cellular uptake, immunohistopathology and immunoscintigraphy. Examination of pathological specimens of human and canine tumor tissue indicated that the expressed antigen was in the β configuration. More than 89% of all human carcinomas tested expressed the antigen in the above anomeric form. The combination of synthetic antigens and monoclonal antibodies raised specifically against them provide us with invaluable tools for the study of tumor marker expression in humans and their respective animal tumor models.

On The Mechanism Of Heparin-Induced Potentiation Of Platelet Aggregation

1981 ◽  
Author(s):  
M Yamamoto ◽  
K Watanabe ◽  
Y Ando ◽  
H Iri ◽  
N Fujiyama ◽  
...  
Keyword(s):  
Platelet Aggregation ◽  
Platelet Activation ◽  
Coagulation Factors ◽  
Marked Enhancement ◽  
Matrix Bound ◽  
Induced Aggregation ◽  
Aggregation Of Platelets ◽  
Plasma Heparin

It has been suggested that heparin caused potentiation of aggregation induced by ADP or epinephrine. The exact mechanism of heparin-induced platelet activation, however, remained unknown. In this paper, we have investigated the role of anti-thrombin III ( AT ) in heparin-induced platelet activation using purified AT and AT depleted plasma. When ADP or epinephrine was added to citrated PRP one minute after addition of heparin ( 1 u/ml, porcine intestinal mucosal heparin, Sigma Co. USA ), marked enhancement of platelet aggregation was observed, compared with the degree of aggregation in the absence of heparin. However, in platelet suspensions prepared in modified Tyrode’s solution, heparin exhibited no potentiating effect on platelet aggregation induced by epinephrine or ADP. Potentiation of epinephrine- or ADP-induced platelet aggregation by heparin was demonstrated when purified AT was added to platelet suspensions at a concentration of 20 μg/ml. AT depleted plasma, which was prepared by immunosorption using matrix-bound antibodies to AT, retained no AT, while determination of α1-antitrypsinα2- macroglobulin and fibrinogen in AT depleted plasma produced values which corresponded to those of the original plasma when dilution factor was taken into account. The activities of coagulation factors were also comparable to those of the original plasma. Heparin exhibited potentiating effect on ADP- or epinephrine-induced aggregation of platelets in original plasma, but no effect in AT depleted plasma. When purified AT was added back to AT depleted plasma at a concentration of 20 μg/ml, potentiation of platelet aggregation by heparin was clearly demonstrated.Our results suggest that effect of heparin on platelet aggregation is also mediated by anti-thrombin III.

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