Identification of the Excitable Cells in the Petiole of Mimosa pudica by Intracellular Injection of Procion Yellow

1983 ◽  
Vol 24 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Michikazu Samejima ◽  
Takao Sibaoka
Keyword(s):  
Mimosa Pudica ◽  
Excitable Cells ◽  
Intracellular Injection ◽  
Procion Yellow

Morphology of Identified Neurones in the Buccal Ganglia of Lymnaea Stagnalis

1979 ◽  
Vol 80 (1) ◽  
pp. 119-135
Author(s):  
P. R. BENJAMIN ◽  
R. M. ROSE ◽  
CAROLE T. SLADE ◽  
M. G. LACY
Keyword(s):  
Salivary Gland ◽  
Lymnaea Stagnalis ◽  
Nerve Roots ◽  
Intracellular Injection ◽  
Buccal Ganglia ◽  
Procion Yellow ◽  
Electrophysiological Findings ◽  
Molluscan Species ◽  
Mass Type

The morphology of seven types of identified neurones in buccal ganglia of Lymnaea was investigated by intracellular injection of Procion Yellow and retrograde injection of cobaltous chloride into the nerve roots of the buccal ganglia. The results provided anatomical support for the electrophysiological findings that some cells are motoneurones for muscles of the buccal mass (type 4-group cells, types 6 and 8 cells). Others project to nerves innervating oesophageal tissue (types 2, 3 and 5 cells) and to pro-oesophageal tissue (types 3 and 5 cells). The type-1 cells project to the salivary gland ducts and are similar to the salivary gland motoneurones found in other molluscan species.

Functional Characterization and Anatomical Identification of Motion Sensitive Neurons in the Lobula plate of the Blowfly Calliphora erythrocephala

1976 ◽  
Vol 31 (9-10) ◽  
pp. 629-634 ◽  
Author(s):  
K. Hausen
Keyword(s):  
Visual Stimulation ◽  
Functional Characterization ◽  
Identified Neurons ◽  
Wide Field ◽  
Calliphora Erythrocephala ◽  
Lobula Plate ◽  
Intracellular Injection ◽  
Procion Yellow

8 classes of homo- and heterolateral wide field neurons of the Lobula plate of Calliphora erythrocephala were investigated electrophysiologically and identified by intracellular injection of procion yellow. All recorded neurons were motion-sensitive. Some of the homolateral neurons respond only with graded potentials to visual stimulation; all heterolateral elements generate spike potentials. Connections between identified neurons were investigated by means of simultaneous double recordings. The described neurons are compared with units known from earlier extracellular studies.

Plasmalemmal transport of magnesium in excitable cells

2000 ◽  
Vol 5 (1) ◽  
pp. d866 ◽  
Author(s):  
Hector Rasgado-Flores
Keyword(s):  
Excitable Cells

Phytochemical, Pharmacological Activities and Ayurvedic Significances of Magical Plant Mimosa pudica Linn

2020 ◽  
Vol 17 ◽  
Author(s):  
Vijay Kumar
Keyword(s):  
Therapeutic Potential ◽  
Wide Spectrum ◽  
Chemical Constituents ◽  
Future Research ◽  
Mimosa Pudica ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
Crude Extracts ◽  
Anti Cancer

: Mimosa pudica Linn is an integrated part of Traditional Medicines Systems of India, China, Africa, Korea and America. It has been used from centuries in traditional medicines to cure different diseases like fever, diabetes, constipation, jaundice, ulcers, biliousness, and dyspepsia. It is an important ingredient of wide class of herbal formulations. To assess the scientific evidence for therapeutic potential of Mimosa pudica Linn and to identify the gaps for future research. The available information on the ethno-medicinal uses, phytochemistry, pharmacology and toxicology of Mimosa pudica Linn was collected via a library and electronic searches in Sci-Finder, Pub-Med, Science Direct, Google Scholar for the period, 1990 to 2020. In traditional medicinal systems, variety of ethno-medicinal applications of Mimosa pudica Linn has been noticed. Phytochemical investigation has resulted in identification of 40 well known chemical constituents, among which alkaloids, phenols and flavionoids are the predominant groups. The crude extracts and isolates have exhibited a wide spectrum of in vitro and in vivo pharmacological activities including anti-cancer, anti-inflammation, osteoporosis, neurological disorders, hypertension etc.. To quantify the Mimosa pudica Linn and its formulations, analytical techniques like HPLC and HPTLC has shown dominancy with good range of recovery and detection limit. Mimosa pudica Linn is the well-known herb since an ancient time. The pharmacological results supported some of the applications of Mimosa pudica Linn in traditional medicine systems. Perhaps, the predominance of alkaloids, phenols and flavionoids are responsible for the pharmacological activities the crude extracts and isolates of Mimosa pudica Linn. Further, there is need to isolate and evaluate the active chemical constituents of Mimosa pudica Linn having significant medicinal values. In future, it is important to study the exact mechanism associated with the phytochemicals of Mimosa pudica Linn especially on anti-cancer activities. Notably, toxicity studies on Mimosa pudica Linn are limited which are to be explored in future for the safe application of Mimosa pudica Linn and its formulations.

Detoxifying Action of Aqueous Extracts of Mucuna pruriens Seed and Mimosa pudica Root Against Venoms of Naja nigricollis and Bitis arietans

2020 ◽  
Vol 14 (2) ◽  
pp. 134-144 ◽  
Author(s):  
Matthew P. Ameh ◽  
Mamman Mohammed ◽  
Yusuf P. Ofemile ◽  
Magaji G. Mohammed ◽  
Ada Gabriel ◽  
...  
Keyword(s):  
Phospholipase A2 ◽  
Plant Extracts ◽  
Fibrinolytic Activity ◽  
Neglected Tropical Diseases ◽  
World Health ◽  
Mucuna Pruriens ◽  
Phytochemical Analysis ◽  
Mimosa Pudica ◽  
Health Organization

Background: The World Health Organization included snakebite envenomation among Neglected Tropical Diseases in 2017. The importance of natural products from plants is enormous, given that most prescribed drugs originate from plants. Among this is Mucuna pruriens and Mimosa pudica, with many registered patents asserting their health benefits. Objective: This study investigated the in vitro neutralizing effects of Mucuna pruriens seed and Mimosa pudica root extracts on venoms of Naja nigricollis and Bitis arietans. Methods: In mice, the LD50 and phytochemical analysis of M. pruriens and M. pudica plant extracts were carried out prior to the evaluation of their haemolytic and fibrinolytic effect. Their effects on the activities of phospholipase A2 (PLA2) were also assessed. Results: At a concentration of 50 mg/ml, both plant extracts were found to neutralize the fibrinolytic activity of N. nigricollis, but 400 mg/ml was required to neutralize the fibrinolytic activity of B. arietans. In haemolytic studies, 50 mg/ml concentration of M. pruriens extract suppressed haemolysis caused by N. nigricollis venom by 70% but at the same concentration, M. pudica extract reduced haemolysis by 49.4%. M. pruriens, at 50 mg/ml concentration, only inhibited phospholipase A2 activity by 7.7% but higher concentrations up to 400mg/ml had no effect against the venom of N. nigricollis; at 200 mg/ml. M. pudica extract inhibited PLA2 activity by 23%. Conclusion: The results suggest that M. pruriens and M. pudica may be considered as promising antivenom agents for people living in a snake-bite prone environment.

scholarly journals Volcano-Shaped Scanning Probe Microscopy Probe for Combined Force-Electrogram Recordings from Excitable Cells

Nano Letters ◽  
2020 ◽  
Vol 20 (6) ◽  
pp. 4520-4529
Author(s):  
B. X. E. Desbiolles ◽  
M. T. M Hannebelle ◽  
E. de Coulon ◽  
A. Bertsch ◽  
S. Rohr ◽  
...  
Keyword(s):  
Scanning Probe Microscopy ◽  
Scanning Probe ◽  
Excitable Cells ◽  
Probe Microscopy

scholarly journals Roles of Microglial Ion Channel in Neurodegenerative Diseases

2021 ◽  
Vol 10 (6) ◽  
pp. 1239
Author(s):  
Alexandru Cojocaru ◽  
Emilia Burada ◽  
Adrian-Tudor Bălșeanu ◽  
Alexandru-Florian Deftu ◽  
Bogdan Cătălin ◽  
...  
Keyword(s):  
Ion Channels ◽  
Neurodegenerative Diseases ◽  
Excitable Cells ◽  
Proton Channels ◽  
Voltage Gated ◽  
Cellular Processes ◽  
Pathological Conditions ◽  
The Common ◽  
Transient Receptor ◽  
The Impact

As the average age and life expectancy increases, the incidence of both acute and chronic central nervous system (CNS) pathologies will increase. Understanding mechanisms underlying neuroinflammation as the common feature of any neurodegenerative pathology, we can exploit the pharmacology of cell specific ion channels to improve the outcome of many CNS diseases. As the main cellular player of neuroinflammation, microglia play a central role in this process. Although microglia are considered non-excitable cells, they express a variety of ion channels under both physiological and pathological conditions that seem to be involved in a plethora of cellular processes. Here, we discuss the impact of modulating microglia voltage-gated, potential transient receptor, chloride and proton channels on microglial proliferation, migration, and phagocytosis in neurodegenerative diseases.

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