scholarly journals Attitudes and Perceptions Toward Authorized Deception: A Pilot Comparison of Healthy Controls and Fibromyalgia Patients

Pain Medicine ◽  
2019 ◽  
Vol 21 (4) ◽  
pp. 794-802
Author(s):  
Susan J Goo ◽  
Eleni Frangos ◽  
Emily A Richards ◽  
Marta Ceko ◽  
Brenda L Justement ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Future Research ◽  
Healthy Controls ◽  
Willingness To Participate ◽  
Chi Square ◽  
Cross Sectional ◽  
Perceptions And Attitudes ◽  
Attitudes And Perceptions ◽  
First Time ◽  
Pain Patients

Abstract Objective Little is known about the perceptions and attitudes of participants who volunteer in studies involving authorized deception. Thus, this cross-sectional pilot study measured, for the first time, the perceptions about participation in an authorized-deception placebo analgesia study in chronic pain patients with fibromyalgia and assessed whether their perceptions differed from healthy controls. Methods An anonymous survey with questions about trust in research and willingness to participate in future research involving deception was mailed to participants in both groups after completion of the parent study. Statistical analyses were performed using the Mann-Whitney U and chi-square tests (31 controls and 16 fibromyalgia patients were included in the analyses). Results The majority of participants expressed little or no concern about the deception, still trusted the scientific process, and found the debriefing procedure helpful and worthwhile. Group differences were found in willingness to 1) participate in the parent study had the deceptive element been disclosed in advance (controls = definitely, fibromyalgia patients = probably, U = 341.5, P = 0.01) and 2) participate in future studies (controls = definitely, fibromyalgia patients = probably, U = 373, P < 0.001). Conclusions Despite slightly less favorable responses of fibromyalgia patients and the relatively small size of the study, these findings suggest that attitudes and perceptions about participating in an authorized placebo study remain positive in both healthy and chronic pain populations.

scholarly journals Prevalence and Characteristics of Chronic Pain in Buprenorphine and Methadone-Maintained Patients

2021 ◽  
Vol 12 ◽  
Author(s):  
Jessica Delorme ◽  
Lucie Pennel ◽  
Georges Brousse ◽  
Jean-Pierre Daulouède ◽  
Jean-Michel Delile ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Illicit Drugs ◽  
Opioid Analgesics ◽  
Cross Sectional Study ◽  
Opioid Agonist ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Chronic Pain Patients ◽  
Associated Risk Factors ◽  
Pain Patients

Chronic pain and substance use disorders frequently co-occur. Indeed, chronic pain is highly prevalent, affecting 23–68% of patients receiving opioid agonist treatments (OAT) worldwide. The majority of available estimates come from American studies, but data are still lacking in Europe. We aim to provide European estimates of the prevalence of chronic pain in patients receiving OAT using French data, since France is the first European country in terms of number of patients with OAT. The secondary objectives were to characterize the features and management of chronic pain, as well identify associated risk factors. We conducted a multicenter, cross-sectional study, recruiting patients treated either with buprenorphine or methadone in 19 French addiction centers, from May to July 2016. All participants had to complete a semi-directed questionnaire that collected sociodemographic and medical data, pain characteristics, and licit or illicit drug consumption. In total, 509 patients were included. The prevalence of chronic pain was estimated at 33.2% (95% CI: 29.1–37.3). Compared to non-chronic pain patients, chronic pain patients were older (38.4 vs. 36.1 years, p = 0.006), were more unemployed (66 vs. 52%, p = 0.003), had more psychiatric comorbidities (50 vs. 39%, p = 0.02), and split their OAT for pain management more frequently (24 vs. 7%, p = 0.009). Pain intensity was moderate or severe in 75% of chronic pain patients. Among patients with chronic pain, 15.4% were not prescribed, and did not self-medicate with, any analgesic drugs, 52.1% were prescribed analgesics (non-opioid analgesics, 76.3%; codeine, tramadol, opium, 27.2%; and morphine, fentanyl, oxycodone, 11.8%), and 32.5% exclusively self-medicated with analgesics. Moreover, 20.1% of patients with chronic pain also used illicit drugs for pain relief. On multivariate analysis, variables that remained significantly associated with chronic pain were age [OR = 1.03 (95% CI: 1.00–1.05], p = 0.02], anxiety [OR = 1.52 (1.15–2.02), p = 0.003], and depression [OR = 1.25 (1.00–1.55), p = 0.05]. Chronic pain is a highly prevalent condition in patients receiving OAT, and its appropriate management remains uncertain, since insufficient relief and frequent additional self-medications with analgesics or illicit drugs were reported by these patients. Increased awareness among caregivers is urgently needed regarding a systematic and careful assessment, along with an adequate management of chronic pain in patients receiving OAT.

Electroencephalography During Nociceptive Stimulation in Chronic Pain Patients: A Systematic Review

Pain Medicine ◽  
2020 ◽  
Vol 21 (12) ◽  
pp. 3413-3427
Author(s):  
Dorine Lenoir ◽  
Ward Willaert ◽  
Iris Coppieters ◽  
Anneleen Malfliet ◽  
Kelly Ickmans ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chronic Pain ◽  
Neuropathic Pain ◽  
Subjective Experience ◽  
Event Related Potential ◽  
High Temporal Resolution ◽  
Healthy Controls ◽  
Somatosensory Processing ◽  
Chronic Pain Patients ◽  
Pain Patients

Abstract Background With its high temporal resolution, electroencephalography (EEG), a technique that records electrical activity of cortical neuronal cells, is a potentially suitable technique to investigate human somatosensory processing. By using EEG, the processing of (nociceptive) stimuli can be investigated, along with the functionality of the nociceptive pathway. Therefore, it can be applied in chronic pain patients to objectify whether changes have occurred in nociceptive processing. Typically, so-called event-related potential (ERP) recordings are used, where EEG signals are recorded in response to specific stimuli and characterized by latency and amplitude. Objective To summarize whether differences in somatosensory processing occur between chronic pain patients and healthy controls, measured with ERPs, and determine whether this response is related to the subjective pain intensity. Design Systematic review. Setting and Methods PubMed, Web of Science, and Embase were consulted, and 18 case–control studies were finally included. Subjects The chronic pain patients suffered from tension-type headache, back pain, migraine, fibromyalgia, carpal tunnel syndrome, prostatitis, or complex regional pain syndrome. Results Chronic neuropathic pain patients showed increased latencies of the N2 and P2 components, along with a decreased amplitude of the N2-P2 complex, which was also obtained in FM patients with small fiber dysfunction. The latter also showed a decreased amplitude of the N2-P3 and N1-P1 complex. For the other chronic pain patients, the latencies and the amplitudes of the ERP components did not seem to differ from healthy controls. One paper indicated that the N2-P3 peak-to-peak amplitude correlates with the subjective experience of the stimulus. Conclusions Differences in ERPs with healthy controls can mostly be found in chronic pain populations that suffer from neuropathic pain or where fiber dysfunction is present. In chronic pain populations with other etiological mechanisms, limited differences were found or agreed upon across studies.

scholarly journals PARACETAMOL DISPENSING PRACTICE OF GOVERNMENT HEALTH CLINICS POST INFANTS’ VACCINATION IN MALAYSIA

2019 ◽  
pp. 33-39
Author(s):  
NURAIN SULEIMAN ◽  
SITI HADIJAH SHAMSUDIN ◽  
RAZMAN MOHD RUS ◽  
SAMSUL DRAMAN
Keyword(s):  
Data Collection ◽  
Positive Association ◽  
Future Research ◽  
Chi Square ◽  
Cross Sectional ◽  
Total Period ◽  
Government Health ◽  
Health Clinics ◽  
Potential Risk Factors ◽  
Collection Form

Objective: This study obtained information on Paracetamol (PCM) Dispensing Practice of Government Health Clinics (GHC) post infants’ vaccination in Malaysia as well as identify its possible factors. Methods: This descriptive cross-sectional retrospective study (with convenient sampling) using a data collection form (DCF) to collect data. The pharmacist who is the representative of the GHC filled the DCF. Potential risk factors were evaluated by Pearson chi-square tests (expected count<5 is<20%) for an independent sample. Results: A total number of 254 samples were collected all over Malaysia within the period of data collection, but only 248 that met inclusion criteria. The PCM dispensing practice of GHC in Malaysia for a total period of 3 y back (from 2015-2017), tend not to give PCM post immunization with respect to age of the upon vaccination and types of vaccination, conversely for gender. Trends of PCM dispensing practice were increasing for “Not Give PCM” with respect to gender, age of the baby upon vaccination, and types of vaccination from 2015 till 2017. The PCM dispensing practice had no association with no statistically significant value (p=0.804) on genders and a weak positive association with statistically significant value (p<0.05 each) on age of the baby (≤ 1year) upon vaccination and types of vaccination. Conclusion: Future research which may include the actual practice in which practices of prescribers or mother may be conducted in determining more accurate data on the giving PCM post infant’s vaccination.

scholarly journals Online paediatric chronic pain management: assessing the needs of UK adolescents and parents, using a cross-sectional survey

2020 ◽  
pp. 204946372094034
Author(s):  
Anna Hurley-Wallace ◽  
Daniel E Schoth ◽  
Suzanne Lilley ◽  
Glyn Williams ◽  
Christina Liossi
Keyword(s):  
Social Media ◽  
Chronic Pain ◽  
Pain Management ◽  
Online Survey ◽  
Interdisciplinary Treatment ◽  
Future Research ◽  
Chronic Pain Management ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Social Media Platforms

Background: Adolescent chronic pain is prevalent, and interdisciplinary treatment is recommended. Although it is well known that technology is a key part of adolescents’ daily lives, there have not been any online, interdisciplinary interventions developed for adolescents with chronic pain in a UK healthcare context. Little is known about how adolescents currently use online resources to manage chronic pain, or what guidance they seek. Methods: Ninety-five participants from the community answered this mixed-methods, online survey (adolescent n = 54, parent n = 41), which assessed the needs of UK-based adolescents for a new online chronic pain management resource. Results: Findings indicated that, at the time of the survey, adolescents frequently used social media platforms, such as Instagram, for chronic pain management. Desired techniques for a new interdisciplinary resource for adolescents included ‘advice on explaining chronic pain to others’ (86.7% of adolescents) and sleep hygiene (82.2% of adolescents), though access to a range of pain management techniques was desired. Qualitative results indicated endorsement of a new programme by adolescents and parents. Conclusions: Adolescents and parents had a positive outlook towards the development of a UK-specific online resource to help manage chronic pain. Such an intervention should aim to be made accessible via the National Health Service. Adolescent use of social media platforms to seek support for chronic pain requires further exploration in future research.

scholarly journals Correlation of Myopia with Physical Exercise and Sleep Habits among Suburban Adolescents

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Yuan Qu ◽  
Jianfeng Yu ◽  
Wei Xia ◽  
Huijuan Cai
Keyword(s):  
Physical Exercise ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Future Research ◽  
Sleep Habits ◽  
Chi Square ◽  
Cross Sectional ◽  
Wake Time ◽  
Potential Association ◽  
Chi Square Test

Purpose. To analyse the correlation of myopia with physical exercise and sleep habits to explore the possible risk or protective factors of juvenile myopia. Methods. This study was a retrospective cross-sectional study. A total of 1831 students aged 11–18 years from five schools in Qingpu completed questionnaires from 2018 to 2019; the students were divided into the nonmyopia group and the myopia group, with students in the myopia group having myopia in at least one eye. Based on the chi-square test, the variables with statistical significance were selected for the logistic regression analysis. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were determined. Results. Myopia was positively associated with older age (OR = 2.216, 95% CI: 1.720–2.855), having a parent with myopia (father: OR = 2.463, 95% CI: 1.900–3.193; mother: OR = 2.853, 95% CI: 2.232–3.646), and a late bedtime during holidays (before 10 pm: p = 0.002; 10 pm-11 pm: OR = 1.516, 95% CI: 1.095–2.100; 11 pm-12 am: OR = 1.966, 95% CI: 1.383–2.795), but negatively correlated with male gender (OR = 0.693, 95% CI: 0.549–0.876), a late daily wake time (OR = 0.782, 95% CI: 0.621–0.985), and having more days per week of outdoor activities during the semester (OR = 0.764, 95% CI: 0.597–0.978). After adjustment for demographic characteristics, myopia was positively associated with a late bedtime during holidays (before 10 pm: p = 0.003; 10 pm-11 pm: OR = 1.570, 95% CI: 1.076–2.289; 11 pm-12 am: OR = 2.173, 95% CI: 1.451–3.253; after 12 am: OR = 1.786, 95% CI: 1.093–2.919), but negatively correlated with a late daily wake time during the semester (OR = 0.761, 95% CI: 0.581–0.997). Conclusion. The association of outdoor exercise with myopia among Chinese suburban adolescents does not seem to be as strong as that of sleep habits. Future research could seek to provide consistent evidence for a potential association between myopia and sleep habits.

Study of the Work Status of Chronic Pain Patients Based on a French Cross-Sectional Survey

2009 ◽  
Vol 51 (12) ◽  
pp. 1361-1362 ◽  
Author(s):  
Alexis Descatha ◽  
Guillermo Jasso-Mosqueda ◽  
Anne-Line Couillerot ◽  
Catherine Rumeau-Pichon ◽  
Anna Ozguler ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Work Status ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Chronic Pain Patients ◽  
Pain Patients

scholarly journals Interactive Computer Method for Rating Quality of Life: Comparison of Chronic Pain Patients and Healthy Controls

Pain Medicine ◽  
2001 ◽  
Vol 2 (4) ◽  
pp. 298-308 ◽  
Author(s):  
Gilbert J. Faniciullo ◽  
Robert N. Jamison ◽  
Marek C. Chawarski ◽  
John C. Baird
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Computer Method ◽  
Healthy Controls ◽  
Chronic Pain Patients ◽  
Pain Patients
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