Prevalence of Metabolic Syndrome in Men with Erectile Dysfunction

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mohamed Abd-Elnaeem Sallam ◽  
Marwa Salah Eldin Zaki ◽  
Mohamed Gamal Elsalibi
Keyword(s):  
Metabolic Syndrome ◽  
Clinical Trials ◽  
Erectile Dysfunction ◽  
Treatment Outcomes ◽  
Cross Sectional Study ◽  
Sexual Medicine ◽  
Sectional Study ◽  
Cross Sectional ◽  
International Consultation ◽  
The Mean

Abstract Background Erectile dysfunction, as defined by the International Consultation on Sexual Medicine, is the consistent and recurrent inability to acquire or sustain an erection of sufficient rigidity and duration to engage in satisfactory sexual intercourse. Objectives The aim of this study was to identify the prevalence of MetS among patients with ED. Patients and Methods This was a cross sectional study conducted on 200 patients attending the Andrology clinic of Dermatology, Venereology and Andrology department, Ain-Shams University starting from March 2019 till December 2019. The 15-question IIEF Questionnaire is a validated, multi- dimensional, self-administered investigation that has been found useful in the clinical assessment of ED and treatment outcomes in clinical trials. Results The mean ± SD of age of patients with ED in our study was 58.3 ± 20.1 years. Out of the 200 patients, 110(55%) of them had BMI (25-29.9). and over 30 in 35(17.5%) patients. The mean ± SD of WC was 41.4±4.9 inches. Among the 200 patients, hypertension was present in 125(62.5%) and smoking in 165 (82.5%) patients. Among the 200 patients, 96 (48%) patients had MetS. Among 200 patients, 90 (45 %) had mild, 54 (27.0 %) had moderate. and 56 (28 %) had severe ED. A significant association was determined between the presence of MetS and severity of ED. The prevalence of moderate and severe ED was significantly higher in patients with MetS than patients without MetS. There was a negative significant correlation between IIEF scores and age, systolic BP, and diastolic BP. Conclusion Among the 200 patients, 96 (48%) patients had MetS. Incidence of moderate to severe ED was higher among patients with MetS versus those without. There was a negative significant correlation between IIEF scores and age, systolic BP, and diastolic BP.

scholarly journals Demographic and Biochemical Parameters of Community Survey Participants with Metabolic Syndrome from Terai Region of Nepal

2021 ◽  
Author(s):  
Birendra Kumar Jha ◽  
Mingma Lhamu Sherpa ◽  
Binod Kumar Dahal ◽  
Jitendra Kumar Singh ◽  
Chamma Gupta
Keyword(s):  
Metabolic Syndrome ◽  
Glucose Tolerance ◽  
Biochemical Parameters ◽  
Central Obesity ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Atherogenic Dyslipidemia ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean

Introduction: The Metabolic Syndrome (MS) is a multifactorial disease associated with central obesity, hypertension, atherogenic dyslipidemia and impaired glucose tolerance. Low grade inflammatory and a prothrombotic state are also involved in MS. Aim: To explore the demographic and biochemical parameters of participants with MS in Terai region of Nepal using community based cross-sectional study. Materials and Methods: A cross-sectional study was carried out during September 2019-December 2019 in adult participants with central obesity (n=378) selected from three districts of Terai region of Nepal. International Diabetes Federation (IDF) criteria were used to define MS. The C-reactive protein-ultra sensitive, fibrinogen, and apolipoprotein-B were estimated as inflammatory, prothrombotic, and atherogenic dyslipidemia markers, respectively. Results: The MS was present in 283 participants with central obesity. The mean (±SD) age, height, weight, and BMI of the participants with MS were 46.36±12.52 years, 5.56±0.11 feet, 66.54±13.45 kg and 27.28±4.98 kg/m2, respectively. The mean (±SD) of biochemical factors were significantly different than their respective normal ranges: decreased serum High Density Lipoprotein (HDL) cholesterol in mg/dL (male: 34.50±9.93, p<0.001, female: 36.77±7.28, p<0.001), raised serum triglycerides level- 184.96±85.72 mg/dL (p<0.001), and impaired fasting serum glucose level 108.14±48.27 mg/dL (p=0.002). Significant increase in inflammatory (CRP-US: 1.12±2.17 mg/L, p<0.001), prothrombotic (fibrinogen: 3.42±1.04 gm/L, p<0.001) and atherogenic dyslipidemia marker (Apo-B: 149.35±59.13 mg/dL, p=0.003) from normal values were observed in subjects with MS. Conclusion: Lowered serum HDL cholesterol, increased triglycerides followed with impaired fasting glucose tolerance were observed as the major abnormal biochemical parameters and increased inflammatory and prothrombotic activities were present among participants with MS.

scholarly journals AGREGASI TROMBOSIT DAN MEAN PLATELET VOLUME DENGAN SINDROM METABOLIK TERKAIT KEGEMUKAN

2018 ◽  
Vol 21 (2) ◽  
pp. 130
Author(s):  
Nindia Sugih Arto ◽  
Adi Koesoema Aman ◽  
Dharma Lindarto
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Platelet Aggregation ◽  
Mean Platelet Volume ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Platelet Volume ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
The Mean

The hyperactivity of platelet had been seen in patients with metabolic syndrome which can be caused by several factors, such as:insulin resistance, obesity, dyslipidemia and hypertension. The hyperactivity of platelet leads to its aggregation that can be increased therisk of cardiovascular disease. This study is aimed to know the platelet aggregation and mean platelet volume in patients with metabolicsyndrome and obesity by determination 30 patients were choosen for this cross sectional study, those whom attended to the laboratoryand policlinic at H. Adam Malik Medan Hospital, between May 2013 until August 2013. The diagnosis used of metabolic syndromecriteria established by the International Diabetic Federation 2005. From the 30 patients with 15 metabolic syndrome and 15 obesity,four patients were excluded because of their tryglyceride were more than 200 mg/dL. There is no significant differences between theplatelet aggregation with the agonist adenosin difosfat (ADP) in patient with metabolic syndrome and obesity. And there is no significantdifferences of the mean platelet volume values between the metabolic syndrome (9.6±0.93) and the obesity group (9.73±0.74), with pvalue 0.846. Based on this study there is no significant differences between the platelet aggregation and the Mean Platelet Volume values(MPV) in the metabolic syndrome and the obese group

scholarly journals Hyperglycemia: the metabolic syndrome component that aggravates erectile dysfunction in Mexican patients

2020 ◽  
Vol 79 (6) ◽  
pp. 1-12
Author(s):  
Alan Espinosa-Marrón ◽  
Christian Anibal Quiñones-Capistrán ◽  
Aquiles Rubio-Blancas ◽  
María Del Pilar Milke-García ◽  
Ricardo Alonso Castillejos-Molina
Keyword(s):  
Metabolic Syndrome ◽  
Erectile Dysfunction ◽  
Glycated Hemoglobin ◽  
Fasting Glucose ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Metabolic Syndrome Components ◽  
Mexican Patients

  Objectives: To analyze the relationship between erectile dysfunction and metabolic syndrome in a group of Mexican patients, study the influence of other morbidity factors on erectile dysfunction, and define the specific metabolic syndrome components most associated with erectile dysfunction severity. Materials and methods: A descriptive, cross-sectional study was conducted on a group of 86 adult Mexican patients previously diagnosed with erectile dysfunction. Participants were classified as presenting with or not presenting with metabolic syndrome. Anthropometric, biochemical, and clinical parameters were determined and erectile dysfunction severity, alcohol or tobacco consumption, and depressive behavior were identified through validated questionnaires. The results were compared between the two groups. Results: The anthropometric measures, laboratory values, and clinical characteristics were significantly different between the two groups. More patients with severe and moderate erectile dysfunction were identified in the group with metabolic syndrome. Of the metabolic syndrome components, glycated hemoglobin >5.7% and fasting glucose >110 mg/dl were significantly associated with the development of erectile dysfunction. Limitations: The size of our study sample was a limitation, as was the observational and cross-sectional study design. Originality: Our study results suggest that metabolic syndrome contributed to the progression of erectile dysfunction in the Mexican sample analyzed, with hyperglycemia being the most strongly associated factor. Conclusions: Metabolic syndrome components were shown to aggravate erectile dysfunction, particularly the lack of glycemic control. The inclusion of fasting glucose and glycated hemoglobin as complementary biochemical screening in patients with erectile dysfunction should be assessed.

scholarly journals Positive Association Between Nutrient Adequacy and Component of Metabolic Syndrome: Outcome of a Cross-sectional Study

2021 ◽  
Author(s):  
Aliyu Tijani Jibril ◽  
Parivash Ghorbaninejad ◽  
Fatemeh Sheikhhossein ◽  
Sakineh Shab-Bidar
Keyword(s):  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Positive Association ◽  
Study Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Vitamin B3 ◽  
Cross Sectional ◽  
Nutrient Adequacy ◽  
The Mean

Abstract ObjectiveMetabolic syndrome (MetS) is a multifactorial disease and its exact causes are not completely clear. Micronutrients such as vitamin A, vitamin D, zinc, and magnesium have been reported to play a role in the improvement of MetS components. We therefore aimed to investigate the association of nutrient adequacy with MetS components.ResultsOf the 850 study subjects, the mean BMI and waist circumference were 27.87 kg/m2 and 92.08 cm respectively, with prevalence of metabolic syndrome at 12.12%. Compared with the least quartile, participants in the highest quartile had a significantly higher scores for general (p=0004) and abdominal (p=0.003) obesity. Overall adequacy of nutrients significantly increased across the quartiles. Energy and all nutrient intakes except for dietary fiber, vitamin B3, and iron were observed to significantly differ among the study groups. In this study, we observed no association between nutrient adequacy and the overall measure of MetS. However, we found a significant positive correlation between the nutrient adequacy and waist circumference, even after all potential covariates were controlled for (p<0.001).

scholarly journals THE INCIDENCE OF ED AFTER TURP AND TVP ON BPH PATIENTS

2012 ◽  
Vol 19 (1) ◽  
Author(s):  
Aries Alpendri ◽  
Tjahyo Kelono Utomo ◽  
Trisula Utomo ◽  
Prawito Singodimedjo
Keyword(s):  
Erectile Dysfunction ◽  
Statistical Analysis ◽  
Cross Sectional Study ◽  
Prostatic Hyperplasia ◽  
Test Results ◽  
Sectional Study ◽  
Exclusion Criteria ◽  
Chi Square ◽  
Cross Sectional ◽  
The Mean

Objective: The aim of this study was to know the incidence of erectile dysfunction (ED) after transurethral resections of the prostate (TURP) and transvesical prostatectomy (TVP). Material & method: Data were collected in 1 year period from January until December 2005 with cross sectional study design. There were 60 patients who met the inclusion and exclusion criteria and patient who participated in this study underwent TURP and TVP and divided in TURP group and TVP group. Erectile Dysfunction measured by International Index of Erectile Function-5 (IIEF-5) data was analyzed by statistic chi-square and independent t-test. Results: Sixty patients include this study with 30 patients in each group. The mean age of TURP was 64 ± 5,68 and TVP was 63,23 ± 4,83 with age ranging from 50 – 70 years. The incidence of ED after TURP and TVP was 36,67% and 16,70% respectively with p = 0,08. The IIEF-5 scores for TURP and TVP was 19,40 ± 3,95 and 21,03 ± 2,57 respectively and by statistical analysis the differences was not significant. Conclusion: The incidence of ED after TURP showed higher than TVP and by statistical analysis the differences was not significant. Keywords: Benign prostatic hyperplasia, erectile dysfunction, transurethral resection of the prostate, transvesical prostatectomy.

Association between metabolic syndrome and thyroid stimulating hormone - A cross sectional study

2019 ◽  
Vol 9 (2) ◽  
pp. 87-90
Author(s):  
Karanam Madhuri ◽  
◽  
Rishi Kumar Venkatachalam ◽  
A Nasreen Begum ◽  
Shamsheer Khan P ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
Sectional Study ◽  
Cross Sectional ◽  
Stimulating Hormone

Comparison of Heffner Criteria and Light Criteria in Differentiating Exudative and Transudative Pleural Effusion

2020 ◽  
Vol 22 (3) ◽  
pp. 141-145
Author(s):  
Krishna Chandra Devkota ◽  
S Hamal ◽  
PP Panta
Keyword(s):  
Pleural Effusion ◽  
Cross Sectional Study ◽  
Pleural Space ◽  
Sectional Study ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
The Common ◽  
The Mean ◽  
Exudative Pleural Effusion

Pleural effusion is present when there is >15ml of fluid is accumulated in the pleural space. It can be divided into two types; exudative and transudative pleural effusion. Tuberculosis and parapneumonic effusion are the common cause of exudative pleural effusion whereas heart failure accounts for most of the cases of transudative pleural effusion. This study was a hospital based cross sectional study performed at Nepal Medical College during the period of January 2016-December 2016. A total of 50 patients who fulfilled the inclusion criteria were enrolled. Pleural effusion was confirmed by clinical examination and radiology. After confirmation of pleural effusion, pleural fluid was aspirated and was analysed for protein, LDH, cholesterol. The Heffner criteria was compared with Light criteria to classify exudative or transudative pleural effusion. Among 50 patients, 30 were male and 20 were female. The mean age of patient was 45.4±21.85 years. The sensitivity and specificity of using Light criteria to detect the two type of pleural effusion was 100% and 90.9%, whereas using Heffner criteria was 94.87%, 100% respectively(P<0.01). There are variety of causes for development of pleural effusion and no one criteria is definite to differentiate between exudative or transudative effusion. In this study Light criteria was more sensitive whereas Heffner criteria was more specific to classify exudative pleural effusion. Hence a combination of criteria might be useful in case where there is difficulty to identify the cause of pleural effusion.

Effect of Medialization of the Trochlear Groove and Lateralization of the Tibial Tubercle on TT-TG Distance: A Cross-sectional Study of Dysplastic and Nondysplastic Knees

2021 ◽  
pp. 036354652098781
Author(s):  
Mathias Paiva ◽  
Lars Blønd ◽  
Per Hölmich ◽  
Kristoffer Weisskirchner Barfod
Keyword(s):  
Trochlear Dysplasia ◽  
Cross Sectional Study ◽  
Magnetic Resonance Images ◽  
Tibial Tubercle ◽  
Control Group ◽  
Trochlear Groove ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mean Values ◽  
The Mean

Background: Tibial tubercle–trochlear groove (TT-TG) distance is often used as a measure of lateralization of the TT and is important for surgical planning. Purpose: To investigate if increased TT-TG distance measured on axial magnetic resonance images is due to lateralization of the TT or medialization of the TG. Study Design: Cross-sectional study; Level of evidence, 3. Methods: A total of 84 knees (28 normal [NK], 28 with trochlear dysplasia [TD], and 28 with patellar dislocation without TD [PD]) were examined. The medial border of the posterior cruciate ligament (PCL) was chosen as the central anatomic landmark. The distance from the TT to PCL (TT-PCL) was measured to examine the lateralization of the TT. The distance from the TG to the PCL (TG-PCL) was measured to examine the medialization of the TG. Between-group differences were investigated by use of 1-way analysis of variance. Results: The mean values for TT-TG distance were 8.7 ± 3.6 mm for NK, 12.1 ± 6.0 mm for PD, and 16.7 ± 4.3 mm in the TD group ( P < .01). The mean values for TT-PCL distance were 18.5 ± 3.6 mm for NK, 18.5 ± 4.5 mm for PD, and 21.2 ± 4.2 mm in the TD group ( P = .03). The mean values for TG-PCL distance were 9.6 ± 3.0 mm for NK, 7.1 ± 3.4 mm for PD, and 5.1 ± 3.3 mm in the dysplastic group ( P < .01). Conclusion: The present results indicate that increased TT-TG distance is due to medialization of the TG and not lateralization of the TT. Knees with TD had increased TT-TG distance compared with the knees of the control group and the knees with PD. The TT-PCL distance did not differ significantly between groups, whereas the TG-PCL distance declined with increased TT-TG.

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