596 Sleep Outcomes and Sleep-Related Behaviors in NICU Graduates

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A235-A235
Author(s):  
Alisa Burnham ◽  
Olena Kucheruk ◽  
Emily Brown ◽  
Jodi Mindell
Keyword(s):  
Sleep Duration ◽  
Normative Data ◽  
Sleep Problems ◽  
Sleep Patterns ◽  
Falling Asleep ◽  
Sleep Parameters ◽  
One Year ◽  
Nighttime Sleep ◽  
Better Than

Abstract Introduction Previous studies of sleep patterns and problems in preterm infants and toddlers have yielded inconsistent results, with some studies noting differences on salient sleep parameters and others indicating similarities. Furthermore, little is known about any differences about sleep-related behaviors. Thus, the current aims of this study were to assess sleep patterns, problems, and sleep-related behaviors in young children born prematurely who were NICU graduates. Methods Caregivers of 262 children (53.4% boys; 35.9% Black, 40.5% White, 23.6% Other) being followed in a neonatal follow-up clinic at their corrected age one-year (10–16 months) or two-year (22–28 month) visit completed the Brief Infant Sleep Questionnaire-Revised SF (BISQ-R SF). Results At approximately one year of age, infants were going to bed at 8:36, taking 33 minutes to fall asleep, and waking .63 times per night for 19 minutes, for a total nighttime sleep duration of 8’01”. Similarly, at approximately two years of age, infants were going to bed at 8:16, taking 26.7 minutes to fall asleep, and waking .94 times per night for 16.3 minutes, for a total nighttime sleep duration of 8’26”. Sleep problems were reported by 18.1% and 19.6% of caregivers, respectively, with the majority indicating that their child slept well (78.5% and 76.5%) and minimal bedtime difficulties (13.6% and 14.6%). The majority of infants slept in their own crib (81%), with infants more likely to room share at 1-year compared to 2-year (49% vs 35%), and almost half falling asleep independently (43% and 46%). Conclusion Overall, sleep patterns and parent-perceived sleep problems (18–20%) in these NICU graduates were better than expected, and similar to normative data of similar age children (Sadeh et al., 2008). However, these infants/toddlers obtained less nighttime (8–8.5 hrs vs 10 hrs). Sleep education of parents of NICU graduates should not only focus on sleep behaviors, but also on ensuring sufficient sleep. Support (if any):

Sleep duration, sleep problems and perceived stress are associated with hippocampal subfield volumes in later life: Findings from The Irish Longitudinal Study on Ageing (TILDA)

SLEEP ◽  
2021 ◽  
Author(s):  
Céline De Looze ◽  
Joanne C Feeney ◽  
Siobhan Scarlett ◽  
Rebecca Hirst ◽  
Silvin P Knight ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Sleep Duration ◽  
Perceived Stress ◽  
Sleep Problems ◽  
Molecular Layer ◽  
Hippocampal Volume ◽  
Ordinary Least Squares ◽  
Cross Sectional ◽  
Stress Changes

Abstract Study Objectives This study examines the cross-sectional and two-year follow-up relationships between sleep and stress and total hippocampal volume and hippocampal subfield volumes among older adults. Methods 417 adults (aged 68.8±7.3; 54% women) from the Irish Longitudinal Study on Ageing completed an interview, a questionnaire and multiparametric brain MRI. The relationships between self-reported sleep duration, sleep problems, perceived stress and total hippocampal volume were examined by using ordinary least squares regressions. Linear mixed-effects models were used to investigate the relationships between sleep duration, sleep problems, perceived stress, changes in these measures over two-years and hippocampal subfield volumes. Results No cross-sectional and follow-up associations between sleep and total hippocampal volume and between stress and total hippocampal volume were found. By contrast, Long sleep (≥9-10 hours / night) was associated with smaller volumes of molecular layer, hippocampal tail, presubiculum and subiculum. The co-occurrence of Short sleep (≤6 hours) and perceived stress was associated with smaller cornu ammonis 1, molecular layer, subiculum and tail. Sleep problems independently and in conjunction with higher stress, and increase in sleep problems over 2 years were associated with smaller volumes of these same subfields. Conclusion Our study highlights the importance of concurrently assessing sub-optimal sleep and stress for phenotyping individuals at risk of hippocampal subfield atrophy.

The prevalence of insomnia and characteristics of sleep patterns collected from sleep diary among medical students of University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam

MedPharmRes ◽  
2021 ◽  
Vol 5 (3) ◽  
pp. 34-38
Author(s):  
Phuong Thi Mai ◽  
Huyen Thi Bui ◽  
Khue Diem Bui
Keyword(s):  
Medical Students ◽  
Associated Factors ◽  
Sleep Problems ◽  
Demographic Data ◽  
Sleep Diary ◽  
Common Disease ◽  
Sleep Patterns ◽  
Cross Sectional Survey ◽  
Falling Asleep ◽  
High Prevalence

Introduction: Insomnia is a common disease in all societies and age groups. Among them, medical students are one of the population most susceptible to sleep problems. Studies from many countries have shown high prevalence of insomnia among medical students. Sleep diary is the gold standard for evaluating subjective insomnia and other sleep disorders. This research aims to study the prevalence of insomnia in Vietnamese medical students, associated factors, and their sleep patterns. Method: In a cross-sectional survey using stratified random sampling, a total of 176 medical students was recruited, each completed a self-administered questionnaire and a 7-consecutive-day sleep diary. Demographic data and lifestyle factors were obtained from the questionnaire, while sleep patterns and quality were collected from the sleep diary. We performed data analysis using SPSS ver 22, p<0.05 was statistically significant. Results: Overall, out of 176 participants, 93 (52.8%) were affected by insomnia. On average, students acquired 6.2 hours of sleep each night. 70.94% of the recorded nights had total sleep time (TST) less than 7 hours. Associated factors of insomnia include sleep environment, sleep efficiency (SE), bedtime, falling asleep time, get up time, self-reported sleep quality. Conclusion: The findings of our study revealed the high prevalence of insomnia among medical students. From recorded sleep data, we observed that sleep deprivation is also a common issue faced by the study participants. The valuable insights provided by sleep diary proved to be crucial in evaluating sleep patterns and quality.

scholarly journals Natural history of excessive daytime sleepiness: a population-based 5-year longitudinal study

SLEEP ◽  
2019 ◽  
Vol 43 (3) ◽  
Author(s):  
I Jaussent ◽  
C M Morin ◽  
H Ivers ◽  
Y Dauvilliers
Keyword(s):  
Sleep Duration ◽  
Excessive Daytime Sleepiness ◽  
Daytime Sleepiness ◽  
Adult Population ◽  
Population Based ◽  
Normal Weight ◽  
Point Reduction ◽  
Nighttime Sleep ◽  
Over Time

Abstract Study Objectives To document the rates of persistent, remitted, and intermittent excessive daytime sleepiness (EDS) in a longitudinal 5-year community study of adults and to assess how changes in risk factors over time can predict improvement of daytime sleepiness (DS). Methods Participants were recruited in 2007–2008 as part of a population-based epidemiological study implemented in Canada. They completed postal assessments at baseline and at each yearly follow-up. An Epworth Sleepiness Scale total score &gt;10 indicated clinically significant EDS; a 4-point reduction between two consecutive evaluations defined DS improvement. Socio-demographic, lifestyle, health characteristics, and sleep-related measures (e.g. insomnia symptoms, sleep duration, sleep medication) were self-reported at each time point. Cox proportional-hazard models were used to predict EDS and DS remissions over 5 years. Results Among the 2167 participants, 33% (n = 714) met criteria for EDS at baseline, of whom 33% had persistent EDS, 44% intermittent EDS, and 23% remitted EDS over the follow-up. Furthermore, 61.4% of 2167 initial participants had stable DS, 27.1% sustained DS improvement and 8.5% transient improvement over the follow-up. The main predictors of EDS remission or DS improvement were normal weight, taking less hypnotics, having hypertension, increased nighttime sleep duration, and decreased insomnia, and depressive symptoms. Conclusions EDS waxes and wanes over time with frequent periods of remission and is influenced by behavioral characteristics and changes in psychological, metabolic, and nighttime sleep patterns. Targeting these predictors in future interventions is crucial to reduce DS in the general adult population.

scholarly journals Sleep problems, behavioural problems and respiratory health in children born extremely preterm: a parental questionnaire study

2019 ◽  
Vol 3 (1) ◽  
pp. e000534
Author(s):  
Kristine Marie Stangenes ◽  
Mari Hysing ◽  
Irene Bircow Elgen ◽  
Thomas Halvorsen ◽  
Trond Markestad ◽  
...  
Keyword(s):  
Sleep Duration ◽  
Daytime Sleepiness ◽  
Inhaled Corticosteroids ◽  
Sleep Problems ◽  
Respiratory Health ◽  
Health Problems ◽  
Behavioural Problems ◽  
Falling Asleep ◽  
Extremely Preterm ◽  
Different Types

ObjectiveTo explore whether children born extremely preterm (EPT) with different types of sleep problems had more behavioural and respiratory health problems than EPT children without sleep problems.DesignProspective, nationwide, questionnaire-based study. At 11 years of age, parents reported on four current sleep problems: difficulty falling asleep or frequent awakenings, snoring, daytime sleepiness and not recommended sleep duration (<9 hours). Behavioural problems were assessed by parents and teachers with the Strengths and Difficulties Questionnaire (SDQ). Parents assessed respiratory symptoms with the International Study of Asthma and Allergies in Childhood questionnaire and described use of asthma medication.SettingNorway.PatientsEPT children.Main outcome measuresSpecified sleep problems, behavioural problems and respiratory health.ResultsData were obtained from 216 of 372 (58 %) of eligible children. All four specified sleep problems were associated with significantly higher parent-reported SDQ total-score (OR 1.1 for all), and except for not recommended sleep duration, also with higher teacher-reported SDQ total-score (OR 1.1 for all). Daytime sleepiness was strongly associated with wheezing last 12 months (OR 3.4), disturbed sleep due to wheezing (OR 3.9), wheeze during or after exercise (OR 2.9), use of inhaled corticosteroids or oral leukotriene modifiers (OR 3.4) and use of bronchodilators (OR 3.9). Snoring was associated with wheezing during or after exercise (OR 2.8) and current asthma (OR 4.2).ConclusionEPT children with different types of sleep problems had more behavioural and respiratory health problems than EPT children without sleep problems.

Circadian dysrhythm and advanced prostate cancer.

2014 ◽  
Vol 32 (4_suppl) ◽  
pp. 199-199
Author(s):  
Lorelei A. Mucci ◽  
Sarah Markt ◽  
Lara Sigurdardottir ◽  
Steven W. Lockley ◽  
Katja Fall ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Circadian Rhythm ◽  
Advanced Prostate Cancer ◽  
Clock Genes ◽  
Sleep Problems ◽  
P Value ◽  
Relative Risks ◽  
Increased Risk ◽  
Falling Asleep

199 Background: The circadian rhythm regulates diverse biologic pathways including tumor oncogenes, metabolism, and cell proliferation. Dysregulation of the circadian rhythm arises from faulty input signals such as exposure to light at night, variability in core circadian rhythm genes, and variation in outputs that regulate circadian behavior including melatonin. There is compelling biologic rationale, but little human data, on circadian dysrhythm and advanced prostate cancer. Methods: We undertook an integrative molecular epidemiology study of circadian dysrhythm and advanced prostate cancer among men in the Icelandic AGES-Reykjavik cohort and the U.S. Health Professionals Follow-up Study, which allowed integration of questionnaire data, biorepositories, and long-term follow-up. We characterized circadian dysrhythm using complimentary approaches: information on sleep problems from questionnaires, prediagnostic melatonin (6-sulfatoxymelatonin) measured on first morning void urine samples, and genetic variation across twelve circadian clock genes. We used multivariable regression models to estimate relative risks (RR) and 95% confidence intervals (CI) of associations with advanced prostate cancer, adjusted for potential confounders. Results: Twenty percent of men reported sleep problems. Men who had trouble falling asleep (RR = 2.1; 95% CI 0.7-6.2) and staying asleep (RR=3.2, 95% CI 1.1-9.7) had an increased risk of developing advanced prostate cancer. Men with sleep problems had significantly lower melatonin levels compared to those without. Low melatonin levels were associated with a statistically significant 4-fold higher risk of advanced prostate cancer compared to those with high levels (95% CI: 1.25-10.0). Variant alleles in two SNPs in cryptochrome (CRY1), involved in generating and maintaining circadian rhythms, were significantly associated with risk of advanced prostate cancer in both cohorts, with a gene-level p-value<0.01. Conclusions: Our results suggest there are multiple nodes in the circadian rhythm that are associated with an increased risk of advanced prostate cancer. As such, there is the potential for complimentary strategies to target circadian disruption and reduce the risk of advanced prostate cancer.

Two psychological treatments for hypochondriasis

1998 ◽  
Vol 173 (3) ◽  
pp. 218-225 ◽  
Author(s):  
David M. Clark ◽  
Paul M. Salkovskis ◽  
Ann Hackmann ◽  
Adrian Wells ◽  
Melanie Fennell ◽  
...  
Keyword(s):  
Stress Management ◽  
Cognitive Therapy ◽  
Specific Treatment ◽  
Post Treatment ◽  
Waiting List ◽  
Control Group ◽  
One Year ◽  
Almost All ◽  
Better Than

BackgroundHypochondriasis is generally considered difficult to manage. This study aimed to assess the effectiveness of cognitive therapy and to compare it with an equally credible, alternative treatment.MethodForty-eight patients with hypochondriasis were initially randomly assigned to either cognitive therapy, behavioural stress management or a no treatment waiting list control group. At the end of the waiting period, patients in the control group were randomly assigned to one of the two treatments. Assessments were at pre-, mid- and post-treatment or waiting list and at three-, six- and 12-month post-treatment follow-up.ResultsComparisons with the waiting list group showed both treatments were effective. Comparisons between the treatments showed that cognitive therapy was more effective than behavioural stress management on measures of hypochondriasis, but not general mood disturbance at mid-treatment and at post-treatment. One year after treatment patients who had received either treatment remained significantly better than before treatment, and on almost all measures the two therapies did not differ from each other.ConclusionsCognitive therapy is a specific treatment for hypochondriasis. Behavioural stress management is also effective but its specificity remains to be demonstrated.

Night-to-Night Variability of Sleep in Children With ADHD and Typically Developing Controls

2015 ◽  
Vol 22 (10) ◽  
pp. 942-946 ◽  
Author(s):  
Abbey Poirier ◽  
Penny Corkum
Keyword(s):  
Mental Health ◽  
Sleep Duration ◽  
Sleep Problems ◽  
Mental Health Disorders ◽  
Typically Developing ◽  
Children With Adhd ◽  
Sleep Parameters ◽  
Health Disorders ◽  
Objective Research ◽  
Age And Sex

Objective: Research results on the nature of sleep problems in children with ADHD are highly inconsistent. It is frequently reported that children with ADHD show more night-to-night variability in sleep than their typically developing (TD) peers, but this finding is also inconsistent. Lack of methodological control may account for these inconsistent findings. The current study examined the night-to-night variability of sleep between TD children and children with ADHD who were rigorously diagnosed, medication naïve, and free from comorbid mental health disorders. Method: Sleep parameters were analyzed for night-to-night variability across 4 weekday nights using actigraphy in 50 children with ADHD and 50 age- and sex-matched TD children. Results: There was a significant night-to-night variability for only sleep duration, but this was similar in both groups. Conclusion: These findings suggest that sleep problems in children with ADHD are not due to greater variability in sleep parameters relative to their TD peers.

scholarly journals Pain, Sleep, and Health-Related Quality of Life after Multidisciplinary Intervention for Chronic Pain

2021 ◽  
Vol 18 (19) ◽  
pp. 10233
Author(s):  
Hafdís Skúladóttir ◽  
Herdis Sveinsdottir ◽  
Janean E. Holden ◽  
Thóra Jenný Gunnarsdóttir ◽  
Sigridur Halldorsdottir ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Pain ◽  
Sleep Problems ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Pre Treatment ◽  
One Year

Multidisciplinary pain-management programs have the potential to decrease pain intensity, improve health-related quality of life (HRQOL), and increase sleep quality. In this longitudinal prospective cohort study, the aim was to investigate the long-term effects of multidisciplinary pain rehabilitation interventions in Iceland. More precisely, we (a) explored and described how individuals with chronic pain evaluated their pain severity, sleep, and HRQOL at pre-treatment and at one-year follow-up and (b) examined what predicted the participants’ one-year follow-up HRQOL. Seventy-nine patients aged 20–68 years, most of whom were women (85%), responded. The participants scored their pain lower at one-year follow-up (p < 0.001). According to their response, most of them had disrupted sleep, mainly because of pain. One year after the treatment, more participants slept through the night (p = 0.004), and their HRQOL increased. Higher pre-treatment mental component summary (MCS) scores and having pursued higher education predicted higher MCS scores at one-year follow-up, and higher pre-treatment physical component summary (PCS) scores predicted higher PCS scores at one-year follow-up. Sleep problems, being a woman, and having children younger than 18 years of age predicted lower MCS scores at one-year follow-up. These findings are suggestive that patients should be examined with respect to their mental status, and it could be beneficial if they received some professional support after completing the intervention.

scholarly journals Sleep Characteristics and Problems of 2-year-olds with Williams Syndrome: Relations with Language and Behavior

2020 ◽  
Author(s):  
Caroline Greiner de Magalhães ◽  
Louise M. O'Brien ◽  
Carolyn B. Mervis
Keyword(s):  
Behavior Problems ◽  
Sleep Duration ◽  
Excessive Daytime Sleepiness ◽  
Daytime Sleepiness ◽  
Externalizing Problems ◽  
Sleep Problems ◽  
Typically Developing ◽  
And Behavior ◽  
Nighttime Sleep ◽  
Nonverbal Reasoning

Abstract Background Sleep problems have been shown to have a negative impact on language development and behavior for both typically developing children and children with a range of neurodevelopmental disorders. The relation of sleep characteristics and problems to language and behavior for children with Williams syndrome (WS) is unclear. The goal of this study was to address these relations for 2-year-olds with WS. Associations of nonverbal reasoning ability, nighttime sleep duration, and excessive daytime sleepiness with language ability and behavior problems were considered. Method: Ninety-six 2-year-olds with genetically confirmed classic-length WS deletions participated. Parents completed the Pediatric Sleep Questionnaire, which includes a Sleep Related Breathing Disorder (SRBD) scale with a subscale measuring excessive daytime sleepiness, to assess sleep characteristics and problems. Parents also completed the Child Behavior Checklist (CBCL) and the MacArthur-Bates Communicative Development Inventory: Words and Sentences to assess behavior problems and expressive vocabulary, respectively. Children completed the Mullen Scales of Early Learning to measure nonverbal reasoning and language abilities. Results Parents indicated that children slept an average of 10.36 hours per night (SD = 1.09, range: 7.3–13.3), not differing significantly from the mean reported by Bell and Zimmerman (2010) for typically developing toddlers (p = .787). Sixteen percent of participants screened positive for SRBD and 30% for excessive daytime sleepiness. Children who screened positive for SRBD had significantly more behavior problems on all CBCL scales than children who screened negative. Children with daytime sleepiness had significantly more attention/hyperactivity, stress, and externalizing problems than those who did not have daytime sleepiness. Individual differences in parent-reported nighttime sleep duration and directly measured nonverbal reasoning abilities accounted for unique variance in expressive language, receptive language, and internalizing problems. Individual differences in parent-reported daytime sleepiness accounted for unique variance in externalizing problems. Conclusions The relations of nighttime sleep duration, positive screens for SRBD, and excessive daytime sleepiness to language and behavior in toddlers with WS parallel prior findings for typically developing toddlers. These results highlight the importance of screening young children with WS for sleep problems. Studies investigating the efficacy of behavioral strategies for improving sleep in children with WS are warranted.

scholarly journals 0318 Prospective Association of Actigraphy-Assessed Sleep with Physical Growth in the First 6 Months of Life

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A121-A121
Author(s):  
X Li ◽  
M Rueschman ◽  
E R Kaplan ◽  
X Yu ◽  
K Davison ◽  
...  
Keyword(s):  
Weight Gain ◽  
Sleep Duration ◽  
Sleep Fragmentation ◽  
Physical Growth ◽  
Birth Cohort Study ◽  
Older Children ◽  
Sleep Patterns ◽  
Rapid Weight Gain ◽  
Term Infants ◽  
Nighttime Sleep

Abstract Introduction Suboptimal sleep is associated with weight gain and related chronic diseases in adults, adolescents, and older children. However, little is known regarding the associations between sleep and physical growth in infants. We investigated prospectively the associations between objectively-measured sleep patterns at 1 month and physical growth in the first 6 months of life. Methods We studied 344 full term infants in the ongoing longitudinal Rise & SHINE (Sleep Health in Infancy & Early Childhood) birth cohort study. At 1 month, infants underwent 7-day ankle actigraphy, estimating average sleep duration (24-hour, nighttime, and daytime) and sleep fragmentation (number of nighttime awakenings). Weight and length were measured at birth and 6 months and used to calculate weight-for-length z (WFL-z) scores. We used linear and logistic regression analyses to examine the associations between sleep patterns at 1 month with WLF-z at 6 months and rapid weight gain from birth to 6 months, defined as an increase in WFL-z greater than or equal to 0.67, controlling for covariates. Results Each 1-hour increase in 24-hour sleep duration was associated with a 0.07-unit (95% CI [0.01, 0.12]) increase in WFL-z at 6 months. Daytime, but not nighttime, sleep duration was positively associated with WFL-z. Greater number of nighttime awakenings was associated with higher WFL-z (beta = 0.28; 95% CI [0.08, 0.49]). 24-hour and nighttime sleep duration were positively associated with a 18.5% (95% CI [1.04, 1.35]) and a 23.4% (95% CI [1.02, 1.49]) higher odds of rapid weight gain from birth to 6 months, respectively. Conclusion Longer 24-hour sleep duration was associated with higher 6-month WFL-z and more rapid increases in WFL-z from birth to 6 months. Greater nighttime sleep fragmentation was associated with higher 6-month WFL-z. Sleep at 1 month might provide modifiable targets to help avoid lifetime complications of excess weight. Support R01DK107972.

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