Saline Nebulization before Gastric Lavage in the Diagnosis of Pulmonary Tuberculosis in Children and Adolescents

Pulmonary tuberculosis may be easily confused with other chest diseases during its initial presentation. This study was carried out to identify presenting clinical and laboratory features that differentiate pulmonary tuberculosis from other diseases and to correlate clinical features and radiological findings. This study was conducted in department of pediatrics and Radiology in Bangabandhu Sheikh Mujib Medical University and Dhaka Shihsu Hospital from July 2005 to June 2006. A total fifty Children below 18 were included in the study after being clinically diagnosed as pulmonary tuberculosis. These patients were subjected to detailed history and, clinical examination. Each patient was evaluated by blood CBC, ESR, Mantoux test, Chest X-ray posterior anterior/lateral view, BCG test and gastric lavage. Statistical analysis was performed by SPSS 8 computer program. Fever, cough, weight loss, night sweats and raised ESR were the most common findings in PTB children. No correlation was found between clinical and laboratory parameters in establishing a confident diagnosis of the disease. The study highlights the importance of further research to pinpoint stronger and more reliable criteria for diagnosis. DOI: http://dx.doi.org/10.3329/bmj.v42i1.18974 Bangladesh Med J. 2013 Jan; 42 (1): 21-24

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Diagnosis of Pulmonary Tuberculosis in Children

Paediatrica Indonesiana ◽

10.14238/pi15.11-12.1975.286-96 ◽

2017 ◽

Vol 15 (11-12) ◽

pp. 286

Author(s):

Gunadi Santosa

Keyword(s):

Mycobacterium Tuberculosis ◽

Pulmonary Tuberculosis ◽

Clinical Diagnosis ◽

Gastric Lavage ◽

Tuberculin Test ◽

Medical Doctor ◽

Definite Diagnosis ◽

Bacteriological Diagnosis ◽

The Moment ◽

Tuberculosis In Children

1. A definite diagnosis of tuberculosis can only be established on the basis of the finding of the tubercle bacilli.2. The isolation of the mycobacterium tuberculosis from a child is subject to difficulties:a. the necessity of gastric lavage for 3 consecutive days, which is difficult to perform ambulatory.b. the necessity of the proper facilities of a microbiologic laboratory.c. the outcome is often not sufficiently high.3. It is concluded that at the moment making of the bacteriological diagnosis of child tuberculosis is not practical, so that we are forced to depend on the clinical diagnosis.4. The tuberculin test is very important in establishing the diagnosis. It is recommended to perform this test routinely on every child once a year and also that every medical doctor as well as specialist performs this test to detect a case of TBC at the earliest possible moment.

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ADULT-TYPE PULMONARY TUBERCULOSIS IN CHILDREN AND ADOLESCENTS, A NESTED CASE-CONTROL STUDY FROM THE SPANISH NETWORK FOR PEDIATRIC TUBERCULOSIS

10.26226/morressier.58fa1764d462b80290b5096c ◽

2017 ◽

Author(s):

Silvia Simo Nebot

Keyword(s):

Pulmonary Tuberculosis ◽

Children And Adolescents ◽

Case Control Study ◽

Case Control ◽

Adult Type ◽

Pediatric Tuberculosis ◽

Tuberculosis In Children ◽

Nested Case Control ◽

Control Study

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Relative Risks of Pulmonary Tuberculosis in Children and Adolescents with Upper Respiratory Tract Infections

10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5157 ◽

2019 ◽

Author(s):

L. Gorbach

Keyword(s):

Pulmonary Tuberculosis ◽

Respiratory Tract ◽

Children And Adolescents ◽

Respiratory Tract Infections ◽

Upper Respiratory Tract Infections ◽

Upper Respiratory Tract ◽

Relative Risks ◽

Upper Respiratory ◽

Tract Infections ◽

Tuberculosis In Children

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Diagnosis of pulmonary tuberculosis in children and adolescents: comparison of two versions of the Brazilian Ministry of Health scoring system

Revista do Instituto de Medicina Tropical de São Paulo ◽

10.1590/s1678-9946202062081 ◽

2020 ◽

Vol 62 ◽

Author(s):

Roberta Feijó Carvalho ◽

Anna Cristina Calçada Carvalho ◽

Luis Guillermo Coca Velarde ◽

Andrea Maciel de Oliveira Rossoni ◽

Rafaela Baroni Aurilio ◽

...

Keyword(s):

Pulmonary Tuberculosis ◽

Children And Adolescents ◽

Scoring System ◽

Ministry Of Health ◽

Tuberculosis In Children

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THE PECULIARITIES OF DETECTION AND DIAGNOSIS OF TUBERCULOSIS IN CHILDREN AND ADOLESCENTS

Vestnik of Vitebsk State Medical University ◽

10.22263/2312-4156.2021.3.40 ◽

2021 ◽

Vol 20 (3) ◽

pp. 40-45

Author(s):

N.S. Pravada ◽

◽

A.M. Budritskiy ◽

V.A. Seryogina ◽

◽

...

Keyword(s):

Multidrug Resistance ◽

Pulmonary Tuberculosis ◽

Children And Adolescents ◽

Tuberculous Infection ◽

Total Blood ◽

Medical Risk ◽

Sick Children ◽

Almost All ◽

Tuberculosis In Children ◽

Family Contact

Objectives. To assess the peculiarities of diagnosis and clinical course of tuberculosis in children and adolescents. Material and methods. Retrospective analysis of outpatient records of children and adolescents with tuberculosis in Vitebsk region during the period from 2016 to 2020 was made. Results. In the tuberculous disease structure in children and adolescents, pulmonary tuberculosis (infiltrative pulmonary tuberculosis) prevails. In the majority of cases, tuberculosis was diagnosed during adolescence. Almost all of the sick had close family contact with tuberculosis patients. The medical risk group included 25% of patients. In patients with infiltrative pulmonary tuberculosis, symptoms and changes in the total blood count were observed only in the phase of disintegration and seeding. Bacteriological excreters made up 75% of cases. More than half of children and adolescents with tuberculosis had multidrug resistance of mycobacterium tuberculosis. Immunodiagnosing plays an important role in the detection of tuberculosis in children and adolescents. Among the sick children, only extrapulmonary forms of tuberculosis were recorded. Conclusions. Most often, tuberculosis in children and adolescents affects the respiratory organs and is asymptomatic or oligosymptomatic. 75% of patients were bacteria discharging persons, more than half of them having multidrug resistance. Family contact is of great importance in tuberculosis in children and adolescents. Doctors of all specialties need to have phthisiatric alertness in relation to patients with diseases of various localization resistant to nonspecific therapy, especially to persons with chronic diseases and to those who contact with patients suffering from tuberculosis. In case of ineffective antibiotic therapy, it is necessary to take the material for the study and verification of tuberculous infection and to carry out immunodiagnosing of tuberculosis.

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Diagnostic value of certain methods for isolation of Mycobacterium tuberculosis in children with suspected pulmonary tuberculosis

Medicinski pregled ◽

10.2298/mpns0506231p ◽

2005 ◽

Vol 58 (5-6) ◽

pp. 231-235 ◽

Cited By ~ 4

Author(s):

Slobodanka Petrovic

Keyword(s):

Mycobacterium Tuberculosis ◽

Pulmonary Tuberculosis ◽

Bronchoalveolar Lavage ◽

Bronchoalveolar Lavage Fluid ◽

Gastric Lavage ◽

Lavage Fluid ◽

Diagnostic Value ◽

Bacteriological Diagnosis ◽

Tuberculosis In Children ◽

Better Than

Introduction The aim of this study was to find out if bronchoalveolar lavage (BL) is better than gastric lavage (GL) or sputum (SP) examination for isolation of Mycobacterium tuberculosis in childhood pulmonary tuberculosis. Material and methods The study included a group of 30 children with suspected pulmonary tuberculosis, aged 6 months to 18 years. Gastric lavage was done on 4 consecutive mornings after overnight fast. Sputum was examined in 12 patients older than 10 years, (4 consecutive samples). BL was performed on the same day as the last GL and SP, using a rigid bronchoscope. Specimens were examined for the existence of BL acid fast bacilli (AFB) and culture for Mycobacterium tb. Results Out of 30 cases, Mycobacterium tb was grown in 13 BL samples (43.33%), and in 10 GL samples from the same patients (33.33%). Comparative analysis of microbiological samples of sputum and bronchoalveolar lavage fluid in 12 children showed that 6 patients had SP+ cultures and 6 patients had SP-cultures of Mycobacterium tb. All SP+ patients where also BL+, but 1 SP- patient was BL+. Smear examination of BL fluid samples was positive for AFB in 10 patients with positive cultures for Mycobacterium tb. Conclusion The results of our study indicate that BL examination is better than GL and SP examination for bacteriological diagnosis of childhood tuberculosis. .

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