Is Routine Monitoring for Hypoglycemia Required in Intramural Asymptomatic Infant of Diabetic Mother? An Audit in a Tertiary Care Hospital

2019 ◽  
Vol 66 (2) ◽  
pp. 194-200
Author(s):  
Jayant Khandare ◽  
Madhusudhan DS ◽  
Anitha Ananthan ◽  
Ruchi Nanavati
Keyword(s):  
Blood Glucose ◽  
Tertiary Care Hospital ◽  
Controlled Trial ◽  
Tertiary Care ◽  
Diabetic Mother ◽  
Blood Glucose Monitoring ◽  
Care Hospital ◽  
Infant Of Diabetic Mother ◽  
Retrospective Audit ◽  
Asymptomatic Infant

Abstract Aims This retrospective audit aimed to analyze whether routine frequent monitoring for hypoglycemia is required in asymptomatic infant of diabetic mother born in tertiary care hospital. Methods The study analyzed the blood sugar level of 196 infants of diabetic mothers. Results The overall incidence of hypoglycemia from 196 study participants was 9.18% (N = 18). The incidence of hypoglycemia at 2 h of life was maximum (83.33%) and it was significant when compared to 3, 6, 9 and 12 h (p < 0.0001). Blood glucose levels were significantly more at 6 (p = 0.0002)), 9 (p = 0.0001) and 12 h (p = 0.0001) when compared to glucose level at 2 h except at 3 h of life (p = 0.062). Similarly blood glucose at 9 (p = 0.0001) and 12 h of life (p = 0.0002) were significantly more than at 3 h of life. Blood glucose at 9 h was significantly more than at 6 h of life (0.032) and at 12 hours of life (p = 0.0237) was significantly higher than at 6 h of life. Conclusion The frequent blood glucose monitoring for hypoglycemia in infant of diabetic mother as per American Academy of Pediatrics may be reduced as per the findings in our study. However, this needs to be confirmed by a properly designed observational study/adequately powered randomized controlled trial.

scholarly journals Association between C reactive protein and obesity: a study in a tertiary care hospital

2019 ◽  
Vol 6 (5) ◽  
pp. 1535
Author(s):  
Lavanya Mandli
Keyword(s):  
Blood Pressure ◽  
Blood Glucose ◽  
Cardiovascular Diseases ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Obese Patients ◽  
Elevated Blood ◽  
C Reactive Protein ◽  
Reactive Protein

Background: Obesity and dyslipidemia, especially in children and adolescents coupled with impaired blood glucose metabolism and elevated blood pressure may result in atherosclerosis in the older ages. This study was conducted to assess the association between high levels of CRP with obesity.Methods: Details including height and weight for BMI and serum for C reactive protein estimation was collected for all 134 patients.Results: 60.4% were females and 49.6% were males. Among the obese patients, clinically raised CRP levels was observed in 29.2% and elevated CRP levels in 45.8% levels, while in overweight patients, 21.4% had clinically raised CRP and 46.4% has elevated CRP levels. In normal BMI patients, elevated CRP was seen in 22% and clinically raised in 1.9%.Conclusion: Detection of CRP levels in overweight and obese patients is imperative in the early stages itself to prevent cardiovascular diseases.

scholarly journals A study of neonatal outcome in infants born to diabetic mothers at a tertiary care hospital

2018 ◽  
Vol 5 (2) ◽  
pp. 489
Author(s):  
Syeda Kausar Anjum ◽  
Yashodha H. T.
Keyword(s):  
Glycemic Control ◽  
Gestational Diabetes ◽  
Tertiary Care Hospital ◽  
Heart Diseases ◽  
Tertiary Care ◽  
Diabetic Mother ◽  
Care Hospital ◽  
Increased Risk ◽  
Diabetic Mothers ◽  
In Pregnancy

Background: Diabetes is the most common medical complication in pregnancy, affecting about 0.5-5% of all pregnancies. In developing countries, management of diabetes in pregnancy still poses a challenge. Infants of diabetic mother are at increased risk of periconceptional, fetal, neonatal and long-term complications. Methods: It was a prospective hospital-based study conducted in tertiary care hospital, Bangalore during a period of one year to assess the outcome in infants of diabetic mother and association of various complications to maternal glycemic status. Results: The incidence of diabetes in pregnant mothers in our hospital was 2.8%. Diabetic mothers with gestational diabetes mellitus (GDM) were 86 (86%) and with pre-gestational diabetes were 14 (14%). Various complications like hypoglycemia, hypocalcemia, polycythemia, hyperbilirubinemia, macrosomia, prematurity, respiratory distress syndrome, TTNB, congenital heart diseases were observed in infants of diabetic mothers. Among them hypoglycemia was the most commonly observed complication with frequency of 54%, followed by hypocalcemia which was seen in 43%, polycythemia in 35% and macrosomia in 15%. Significant association was found between various complications and glycemic control in mothers.Conclusions: High frequency of complications is seen in infants born to diabetic mothers. Hence, these babies should be delivered at hospitals where special neonatal care is available for management of high risks babies. Screening for GDMs should be performed in all pregnant women. Strict glycemic control in mother, planned pregnancy, proper antenatal care and strict monitoring in babies is required to prevent morbidity and mortality in infants of diabetic mother.

scholarly journals COMPARISON OF MICRONIZED PROGESTERONE (CYCLOGEST PESSARY) AND PLACEBO IN PREVENTION OF PRE-TERM BIRTH IN TERTIARY CARE HOSPITAL

2020 ◽  
Vol 70 (6) ◽  
pp. 1859-63
Author(s):  
Nighat Afridi ◽  
Ambreen Fatima ◽  
Amna Fareed ◽  
Saifullah Khan ◽  
Shah Gul Khan
Keyword(s):  
Preterm Birth ◽  
Tertiary Care Hospital ◽  
Positive Impact ◽  
Controlled Trial ◽  
Tertiary Care ◽  
Length Of Hospital Stay ◽  
P Value ◽  
Care Hospital ◽  
Gynecology And Obstetrics ◽  
Micronized Progesterone

Objective: To compare efficacy of micronized per rectal progesterone (cyclogest pessary) and placebo inprevention of preterm birth in tertiary care hospital. Study Design: Randomized controlled trial (RCT). Place and Duration of Study: Study was conducted at department of gynecology and Obstetrics, CombinedMilitary Hospital Nowshera, Khyber Pakhtunkhwa, from Jan 2018 to Jun 2018. Methodology: A sample size of 140 patients was calculated using WHO calculator. Non probability consecutivesampling was used for recruitment of participants. Ethics approval and consent forms were taken. Women weredivided into two groups randomly. Group A was given micronized progesterone (cyclogest pessary) per rectalusage and group B was given placebo. Patients were followed for maternal and neonatal outcomes. Data wasanalyzed using SPSS version 23. Independent t-test was applied. p-value ≤0.05 was considered significant. Results: Total 140 patients were included in study. Mean age of women was 29.4 years ± 4.6SD. Patients in micronized progesterone (cyclogest pessary) was more effective in increasing birth weight (p=0.00), Apgar score maintenance at 1st (p=0.00) and 5th minute (p=0.000) and reduction in length of hospital stay (p=0.000) as compared to placebo. Patients were more satisfied with micronized progesterone (cyclogest pessary) per rectal as compared to placebo (p=0.00). Conclusion: Preterm birth is remained as significant issue in health care system of Pakistan. However, micronized progesterone (cyclogest pessary) per rectal usage had positive impact in improving maternal and neonatal health outcomes. Effective strategies for prevention of preterm birth in Pakistan are required.

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