scholarly journals Significant Influence of EC50 Estimation by Model Choice and EC50 Type

Plant Disease ◽  
2018 ◽  
Vol 102 (4) ◽  
pp. 708-714 ◽  
Author(s):  
Zachary A. Noel ◽  
Jie Wang ◽  
Martin I. Chilvers
Keyword(s):  
Dose Response ◽  
Logistic Models ◽  
Effective Control ◽  
Model Choice ◽  
Fusarium Virguliforme ◽  
Future Studies ◽  
Software Packages ◽  
The Difference ◽  
Using Data ◽  
Set Up

The effective control to 50% growth inhibition (EC50) is a standard statistic for evaluating dose-response relationships. Many statistical software packages are available to estimate dose-response relationships but, recently, an open source package (“drc”) in R has been utilized. This package is highly adaptable, having many models to describe dose-response relationships and flexibility to describe both hormetic relationships and absolute and relative EC50. These models and definitions are generally left out of phytopathology literature. Here, we demonstrate that model choice and type of EC50 (relative versus absolute) can matter for EC50 estimation using data from Pythium oopapillum and Fusarium virguliforme. For some P. oopapillum isolates, the difference between absolute and relative EC50 was significant. Hormetic effects changed F. virguliforme EC50 distributions, leading to higher estimates than when using four- or three-parameter log-logistic models. Future studies should pay careful attention to model selection and interpretation in EC50 estimation and clearly indicate which model and EC50 measure (relative versus absolute) was used. We provide guidelines for model choice and interpretation for those wishing to set up experiments for accurate EC50 estimation.

scholarly journals Integration of various scales for measurement of insomnia

2021 ◽  
pp. 263208432110100
Author(s):  
Satyendra Nath Chakrabartty
Keyword(s):  
Test Scores ◽  
Data Driven ◽  
Weighted Sum ◽  
Future Studies ◽  
Normal Probability ◽  
Equivalent Test ◽  
Item Scores ◽  
Using Data ◽  
Set Up ◽  
Different Levels

Background Scales for evaluating insomnia differ in number of items, response format, and result in different scores distributions and score ranges and may not facilitate meaningful comparisons. Objectives Transform ordinal item-scores of three scales of insomnia to continuous, equidistant, monotonic, normally distributed scores, avoiding limitations of summative scoring of Likert scales. Methods Equidistant item-scores by weighted sum using data-driven weights to different levels of different items, considering cell frequencies of Item-Levels matrix, followed by normalization and conversion to [1, 10]. Equivalent test-scores (as sum of transformed item- scores) for a pair of scales were found by Normal Probability curves. Empirical illustration given. Results Transformed test-scores are continuous, monotonic and followed Normal distribution with no outliers and tied scores. Such test-scores facilitate ranking, better classification and meaningful comparison of scales of different lengths and formats and finding equivalent score combinations of two scales. For a given value of transformed test-score of a scale, easy alternate method avoiding integration proposed to find equivalent scores of another scales. Equivalent scores of scales help to relate various cut-off scores of different scales and uniformity in interpretations. Integration of various scales of insomnia is achieved by finding one-to-one correspondence among the equivalent score of various scales with correlation over 0.99 Conclusion Resultant test-scores facilitated undertaking analysis in parametric set up. Considering the theoretical advantages including meaningfulness of operations, better comparison, use of such method of transforming scores of Likert items/test is recommended test and items, Future studies were suggested.

Financial inclusion and FinTech

2019 ◽  
Vol 12 (1) ◽  
pp. 24-42 ◽  
Author(s):  
Hasnan Baber
Keyword(s):  
World Bank ◽  
Design Methodology ◽  
Financial Inclusion ◽  
Islamic Finance ◽  
Financial Systems ◽  
Content Type ◽  
Future Studies ◽  
Finance System ◽  
The Difference ◽  
Using Data

Purpose Using data from World Bank and Global Islamic Finance Report, this paper aims to compare the performance of countries following Islamic and conventional finance system in terms of financial inclusion and FinTech. Design/methodology/approach Ten countries from both financial systems have been selected based on the presence of Islamic finance and conventional finance in the country. Data was analyzed from year 2011 to 2017 and keeping the former as base year to measure the change in the population fraction. Findings The findings found that Islamic finance countries are more inclusive in terms of financial inclusion and women are financially more empowered as compared to the counterpart. On the contrary, countries with conventional finance have a higher number of FinTech users. Research limitations/implications The difference between the performances of two systems in terms of financial inclusion is relatively small; therefore, future studies should incorporate more indicators for financial inclusion. Originality/value This study will be useful for understanding the nature of both financial systems, and the further research can be done to find the determinants of financial inclusion.

Experimental Investigation into Driver Behavior along Curved and Parallel Diverging Terminals of Exit Interchange Ramps

2021 ◽  
pp. 036119812199742
Author(s):  
Alberto Portera ◽  
Marco Bassani
Keyword(s):  
Design Stage ◽  
Lane Change ◽  
Age And Gender ◽  
Traffic Conditions ◽  
Current Design ◽  
The Difference ◽  
Safety Countermeasures ◽  
And Gender ◽  
Set Up ◽  
Curve Radius

Current design manuals provide guidance on how to design exit ramps to facilitate driving operations and minimize the incidence of crashes. They also suggest that interchanges should be built along straight roadway sections. These criteria may prove ineffective in situations where there is no alternative to terminals being located along curved motorway segments. The paper investigates driving behavior along parallel deceleration curved terminals, with attention paid to the difference in impact between terminals having a curvature which is the same sign as the motorway segment (i.e., continue design), and those having an opposite curvature (i.e., reverse design). A driving simulation study was set up to collect longitudinal and transversal driver behavioral data in response to experimental factor variations. Forty-eight drivers were stratified on the basis of age and gender, and asked to drive along three randomly assigned circuits with off-ramps obtained by combining experimental factors such as motorway mainline curve radius (2 values), terminal length (3), curve direction (2), and traffic conditions (2). The motorway radius was found to be significant for drivers’ preferred speed when approaching the terminal. Terminal length and traffic volume do not have a significant impact on either longitudinal or transversal driver outputs. However, the effect of curve direction was found to be significant, notably for reverse terminals which do not compel drivers to select appropriate speeds and lane change positions. This terminal type can give rise to critical driving situations that should be considered at the design stage to facilitate the adoption of appropriate safety countermeasures.

scholarly journals Deep learning for cephalometric landmark detection: systematic review and meta-analysis

2021 ◽  
Author(s):  
Falk Schwendicke ◽  
Akhilanand Chaurasia ◽  
Lubaina Arsiwala ◽  
Jae-Hong Lee ◽  
Karim Elhennawy ◽  
...  
Keyword(s):  
Systematic Review ◽  
Deep Learning ◽  
Meta Analysis ◽  
High Accuracy ◽  
Risk Of Bias ◽  
Automated Detection ◽  
Reference Test ◽  
Landmark Detection ◽  
Future Studies ◽  
Using Data

Abstract Objectives Deep learning (DL) has been increasingly employed for automated landmark detection, e.g., for cephalometric purposes. We performed a systematic review and meta-analysis to assess the accuracy and underlying evidence for DL for cephalometric landmark detection on 2-D and 3-D radiographs. Methods Diagnostic accuracy studies published in 2015-2020 in Medline/Embase/IEEE/arXiv and employing DL for cephalometric landmark detection were identified and extracted by two independent reviewers. Random-effects meta-analysis, subgroup, and meta-regression were performed, and study quality was assessed using QUADAS-2. The review was registered (PROSPERO no. 227498). Data From 321 identified records, 19 studies (published 2017–2020), all employing convolutional neural networks, mainly on 2-D lateral radiographs (n=15), using data from publicly available datasets (n=12) and testing the detection of a mean of 30 (SD: 25; range.: 7–93) landmarks, were included. The reference test was established by two experts (n=11), 1 expert (n=4), 3 experts (n=3), and a set of annotators (n=1). Risk of bias was high, and applicability concerns were detected for most studies, mainly regarding the data selection and reference test conduct. Landmark prediction error centered around a 2-mm error threshold (mean; 95% confidence interval: (–0.581; 95 CI: –1.264 to 0.102 mm)). The proportion of landmarks detected within this 2-mm threshold was 0.799 (0.770 to 0.824). Conclusions DL shows relatively high accuracy for detecting landmarks on cephalometric imagery. The overall body of evidence is consistent but suffers from high risk of bias. Demonstrating robustness and generalizability of DL for landmark detection is needed. Clinical significance Existing DL models show consistent and largely high accuracy for automated detection of cephalometric landmarks. The majority of studies so far focused on 2-D imagery; data on 3-D imagery are sparse, but promising. Future studies should focus on demonstrating generalizability, robustness, and clinical usefulness of DL for this objective.

The Impact of Customer Loyalty and Restaurant Sanitation Grades on Revisit Intention and the Importance of Narrative Information: The Case of New York Restaurant Sanitation Grading System

2017 ◽  
Vol 59 (3) ◽  
pp. 275-284 ◽  
Author(s):  
Min Gyung Kim ◽  
Hyunjoo Yang ◽  
Anna S. Mattila
Keyword(s):  
New York ◽  
New York City ◽  
Customer Loyalty ◽  
York City ◽  
Letter Grades ◽  
The Difference ◽  
Revisit Intentions ◽  
Using Data ◽  
The Impact ◽  
Loyal Customers

New York City launched a restaurant sanitation letter grade system in 2010. We evaluate the impact of customer loyalty on restaurant revisit intentions after exposure to a sanitation grade alone, and after exposure to a sanitation grade plus narrative information about sanitation violations (e.g., presence of rats). We use a 2 (loyalty: high or low) × 4 (sanitation grade: A, B, C, or pending) between-subjects full factorial design to test the hypotheses using data from 547 participants recruited from Amazon MTurk who reside in the New York City area. Our study yields three findings. First, loyal customers exhibit higher intentions to revisit restaurants than non-loyal customers, regardless of sanitation letter grades. Second, the difference in revisit intentions between loyal and non-loyal customers is higher when sanitation grades are poorer. Finally, loyal customers are less sensitive to narrative information about sanitation violations.

Pump Performance Improvement by Restraining Back Flow in Screw-Type Centrifugal Pump

2005 ◽  
Vol 127 (4) ◽  
pp. 755-762 ◽  
Author(s):  
Yasushi Tatebayashi ◽  
Kazuhiro Tanaka ◽  
Toshio Kobayashi
Keyword(s):  
Pressure Fluctuations ◽  
Centrifugal Pumps ◽  
Two Phase ◽  
Simple Method ◽  
Back Flow ◽  
Pump Performance ◽  
Impeller Outlet ◽  
Pump Head ◽  
The Difference ◽  
Set Up

The authors have been investigating the various characteristics of screw-type centrifugal pumps, such as pressure fluctuations in impellers, flow patterns in volute casings, and pump performance in air-water two-phase flow conditions. During these investigations, numerical results of our investigations made it clear that three back flow regions existed in this type of pump. Among these, the back flow from the volute casing toward the impeller outlet was the most influential on the pump performance. Thus the most important factor to achieve higher pump performance was to reduce the influence of this back flow. One simple method was proposed to obtain the restraint of back flow and so as to improve the pump performance. This method was to set up a ringlike wall at the suction cover casing between the impeller outlet and the volute casing. Its effects on the flow pattern and the pump performance have been discussed and clarified to compare the calculated results with experimental results done under two conditions, namely, one with and one without this ring-type wall. The influence of wall’s height on the pump head was investigated by numerical simulations. In addition, the difference due to the wall’s effect was clarified to compare its effects on two kinds of volute casing. From the results obtained it can be said that restraining the back flow of such pumps was very important to achieve higher pump performance. Furthermore, another method was suggested to restrain back flow effectively. This method was to attach a wall at the trailing edge of impeller. This method was very useful for avoiding the congestion of solids because this wall was smaller than that used in the first method. The influence of these factors on the pump performance was also discussed by comparing simulated calculations with actual experiments.

Comparing two definitions of ethnicity for identifying young persons at risk for chlamydia

2011 ◽  
Vol 140 (5) ◽  
pp. 951-958 ◽  
Author(s):  
A. HAASNOOT ◽  
F. D. H. KOEDIJK ◽  
E. L. M. OP DE COUL ◽  
H. M. GÖTZ ◽  
M. A. B. VAN DER SANDE ◽  
...  
Keyword(s):  
Odds Ratio ◽  
Ethnic Disparities ◽  
Chlamydia Infection ◽  
Chlamydia Screening ◽  
Country Of Birth ◽  
Regression Modelling ◽  
Explained Variation ◽  
The Difference ◽  
Using Data ◽  
Logistic Regression Modelling

SUMMARYEthnic disparities in chlamydia infections in The Netherlands were assessed, in order to compare two definitions of ethnicity: ethnicity based on country of birth and self-defined ethnicity. Chlamydia positivity in persons aged 16–29 years was investigated using data from the first round of the Chlamydia Screening Implementation (CSI, 2008–2009) and surveillance data from STI centres (2009). Logistic regression modelling showed that being an immigrant was associated with chlamydia positivity in both CSI [adjusted odds ratio (aOR) 2·3, 95% confidence interval (CI) 2·0–2·6] and STI centres (aOR 1·4, 95% CI 1·3–1·5). In both settings, 60% of immigrants defined themselves as Dutch. Despite the difference, classification by self-defined ethnicity resulted in similar associations between (non-Dutch) ethnicity and chlamydia positivity. However, ethnicity based on country of birth explained variation in chlamydia positivity better, and is objective and constant over time and therefore more useful for identifying young persons at higher risk for chlamydia infection.

POSTPARTUM AMENORRHOEA IN RURAL EASTERN UTTAR PRADESH, INDIA

1998 ◽  
Vol 30 (2) ◽  
pp. 227-243
Author(s):  
K. N. S. YADAVA ◽  
S. K. JAIN
Keyword(s):  
Higher Education ◽  
Uttar Pradesh ◽  
Current Status Data ◽  
North India ◽  
Current Status ◽  
Data Sets ◽  
Survival Status ◽  
The Mean ◽  
The Difference ◽  
Using Data

This paper calculates the mean duration of the postpartum amenorrhoea (PPA) and examines its demographic, and socioeconomic correlates in rural north India, using data collected through 'retrospective' (last but one child) as well as 'current status' (last child) reporting of the duration of PPA.The mean duration of PPA was higher in the current status than in the retrospective data;n the difference being statistically significant. However, for the same mothers who gave PPA information in both the data sets, the difference in mean duration of PPA was not statistically significant. The correlates were identical in both the data sets. The current status data were more complete in terms of the coverage, and perhaps less distorted by reporting errors caused by recall lapse.A positive relationship of the mean duration of PPA was found with longer breast-feeding, higher parity and age of mother at the birth of the child, and the survival status of the child. An inverse relationship was found with higher education of a woman, higher education of her husband and higher socioeconomic status of her household, these variables possibly acting as proxies for women's better nutritional status.

A COMPARISON OF THE ACTIVITY OF SOME PRO-OESTROGENS ADMINISTERED SUBCUTANEOUSLY AND INTRAVENOUSLY

1964 ◽  
Vol 29 (2) ◽  
pp. 159-165
Author(s):  
G. M. STONE
Keyword(s):  
Dose Response ◽  
Routes Of Administration ◽  
The Difference ◽  
Response Line

SUMMARY In the tetrazolium assay of Martin (1960) all the pro-oestrogens tested, except racemic-butoestrol, were active intravenously but both true oestrogens and pro-oestrogens were more effective subcutaneously. The difference between the two routes of administration was greater with the pro-oestrogens. These results indicate that in this assay the slope of the dose-response line for pro-oestrogens is lower than that for true oestrogens.

scholarly journals A Webgis Framework for Disseminating Processed Remotely Sensed on Land Cover Transformations

2016 ◽  
Vol 100 (1) ◽  
pp. 27-38 ◽  
Author(s):  
Grazia Caradonna ◽  
Antonio Novelli ◽  
Eufemia Tarantino ◽  
Raffaela Cefalo ◽  
Umberto Fratino
Keyword(s):  
Land Cover ◽  
Satellite Data ◽  
Vegetation Indices ◽  
Remote Sensing Data ◽  
Geospatial Data ◽  
Usage Patterns ◽  
Mediterranean Regions ◽  
Multi Temporal ◽  
Using Data ◽  
Set Up

Abstract Mediterranean regions have experienced significant soil degradation over the past decades. In this context, careful land observation using satellite data is crucial for understanding the long-term usage patterns of natural resources and facilitating their sustainable management to monitor and evaluate the potential degradation. Given the environmental and political interest on this problem, there is urgent need for a centralized repository and mechanism to share geospatial data, information and maps of land change. Geospatial data collecting is one of the most important task for many users because there are significant barriers in accessing and using data. This limit could be overcome by implementing a WebGIS through a combination of existing free and open source software for geographic information systems (FOSS4G). In this paper we preliminary discuss methods for collecting raster data in a geodatabase by processing open multi-temporal and multi-scale satellite data aimed at retrieving indicators for land degradation phenomenon (i.e. land cover/land use analysis, vegetation indices, trend analysis, etc.). Then we describe a methodology for designing a WebGIS framework in order to disseminate information through maps for territory monitoring. Basic WebGIS functions were extended with the help of POSTGIS database and OpenLayers libraries. Geoserver was customized to set up and enhance the website functions developing various advanced queries using PostgreSQL and innovative tools to carry out efficiently multi-layer overlay analysis. The end-product is a simple system that provides the opportunity not only to consult interactively but also download processed remote sensing data.

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