Effect of meal composition on postprandial blood glucose levels in middle aged and young adults (1107.6)

Objective: Diabetes mellitus is a leading cause of death and disability in the world and its prevalence is predicted to rise to 10% by 2030. Hence, this study is conducted with objectives to find out the effect of aerobic exercises and resisted exercises on blood glucose levels in type 2 diabetes mellitus (T2DM) subjects and to compare the effect of both exercises on blood glucose level.Method: The comparative study was conducted at Krishna Institute of Medical Sciences Deemed University, Physiotherapy department, Karad. 30 participants with age group between 30 and 65 years were taken. Subjects were selected as per inclusion and exclusion criteria. Group A (15) participants were given aerobic exercise on static bicycle, and Group B (15) participants were given resistance training using dumbbells and weight cuffs for 5 days/week for 4 weeks. Diet recommendations were given to every participant.Results: Statistical analysis was performed using paired and unpaired t-test. Analysis showed statistically extremely significant difference in fasting blood glucose level and postprandial blood glucose level in both the groups (p≤0.0001).Conclusion: Thus, this study concludes that both aerobic exercises and resistance training prove to be beneficial in controlling blood glucose levels in T2DM subjects.

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Effects of metformin, acarbose, and sitagliptin monotherapy on gut microbiota in Zucker diabetic fatty rats

BMJ Open Diabetes Research & Care ◽

10.1136/bmjdrc-2019-000717 ◽

2019 ◽

Vol 7 (1) ◽

pp. e000717 ◽

Cited By ~ 10

Author(s):

Minchun Zhang ◽

Rilu Feng ◽

Mei Yang ◽

Cheng Qian ◽

Zheng Wang ◽

...

Keyword(s):

Blood Glucose ◽

Gut Microbiota ◽

Relative Abundance ◽

16S Rrna Gene Sequencing ◽

Postprandial Blood Glucose ◽

Saline Control ◽

Rrna Gene ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Zucker Diabetic Fatty Rats

ObjectiveRecent studies have demonstrated that gut microbiota was closely related to metabolic disorders such as type 2 diabetes. Oral antidiabetic medications including metformin, acarbose and sitagliptin lowered blood glucose levels via acting on the gastrointestinal tract. The aim of the study was to observe the comparisons among those medications on gut microbiota composition.Research design and methodsZucker diabetic fatty rats (n=32) were randomly divided into four groups, and had respectively gastric administration of normal saline (control), metformin (215.15 mg/kg/day), acarbose (32.27 mg/kg/day), or sitagliptin (10.76 mg/kg/day) for 4 weeks. Blood glucose levels were measured during an intragastric starch tolerance test after the treatments. 16S rRNA gene sequencing was used to access the microbiota in the fecal samples.ResultsMetformin, acarbose, and sitagliptin monotherapy effectively decreased fasting and postprandial blood glucose levels (p<0.001). Acarbose group displayed specific cluster and enterotype mainly composed byRuminococcus 2whileLactobacilluswas the dominant bacterium in the enterotype of the other three groups. The relative abundance of generaRuminococcus 2andBifidobacteriumwas dramatically higher in acarbose group. Metformin and sitagliptin increased the relative abundance of genus Lactobacillus. Metagenomic prediction showed that the functional profiles of carbohydrate metabolism were enriched in acarbose group.ConclusionsMetformin, acarbose and sitagliptin exerted different effects on the composition of gut microbiota and selectively increased the beneficial bacteria. Supplementation with specific probiotics may further improve the hypoglycemic effects of the antidiabetic drugs.

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No Association between Elevated 2-h Postprandial Blood Glucose Levels and Functional Outcomes of Small-Artery Occlusion in Patients with Diabetes

Frontiers in Neurology ◽

10.3389/fneur.2018.00093 ◽

2018 ◽

Vol 9 ◽

Author(s):

Ji Liu ◽

Dongzhe Hou ◽

Yuan Gao ◽

Jialing Wu

Keyword(s):

Blood Glucose ◽

Functional Outcomes ◽

Artery Occlusion ◽

Postprandial Blood Glucose ◽

Small Artery ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Small Artery Occlusion ◽

Patients With Diabetes

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Swallowing food without chewing; a simple way to reduce postprandial glycaemia

British Journal Of Nutrition ◽

10.1079/bjn19860008 ◽

1986 ◽

Vol 55 (1) ◽

pp. 43-47 ◽

Cited By ~ 81

Author(s):

N. W. Read ◽

I. McL. Welch ◽

C. J. Austen ◽

C. Barnish ◽

C. E. Bartlett ◽

...

Keyword(s):

Blood Glucose ◽

Slow Release ◽

The Other ◽

Postprandial Blood Glucose ◽

Glycaemic Response ◽

Healthy Human ◽

White Rice ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Human Volunteers

1. The degree to which disruption by mastication affects the glycaemic response to four different carbohydrate foods was investigated in healthy human volunteers; each food was eaten by six subjects.2. Subjects ate meals of sweetcorn, white rice, diced apple or potato on two occasions; on one occasion they chewed the food thoroughly, on the other occasion they swallowed each mouthful without chewing it.3. When the foods were chewed the postprandial blood glucose levels rose to levels which vaned according to the food ingested.4. Swallowing without chewing reduced the glycaemic response to each food, achieving a similar effect as administration of viscous polysaccharides or ‘slow-release’ carbohydrates.

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Effects on a Soft Drink Containing Indigestible Dextrin on Postprandial Blood Glucose Levels in Healthy Volunteer

Journal for the Integrated Study of Dietary Habits ◽

10.2740/jisdh.14.221 ◽

2003 ◽

Vol 14 (3) ◽

pp. 221-225 ◽

Cited By ~ 1

Author(s):

Atsushi Kondo ◽

Syoichi Kurihara ◽

Hiroko Sato ◽

Kunihiko Ishitani

Keyword(s):

Blood Glucose ◽

Healthy Volunteer ◽

Soft Drink ◽

Postprandial Blood Glucose ◽

Glucose Levels ◽

Blood Glucose Levels

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Prevention of Abrupt Increases in Postprandial Blood Glucose Levels by Rice Bread Made with the Novel Rice Cultivar “Konayukinomai”

Food Science and Technology Research ◽

10.3136/fstr.22.793 ◽

2016 ◽

Vol 22 (6) ◽

pp. 793-799 ◽

Cited By ~ 2

Author(s):

Wataru Noro ◽

Ryuichiro Akaishi ◽

Sumiko Nakamura ◽

Ken'ichi Ohtsubo ◽

Hideo Maeda ◽

...

Keyword(s):

Blood Glucose ◽

Rice Cultivar ◽

Postprandial Blood Glucose ◽

The Novel ◽

Glucose Levels ◽

Blood Glucose Levels

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Korelasi Lingkar Pinggang dengan Kadar Gula Darah Puasa, Kadar Trigliserida, dan Tekanan Darah pada Mahasiswa Fakultas Kedokteran Universitas HKBP Nommensen

Health & Medical Journal ◽

10.33854/heme.v3i2.583 ◽

2021 ◽

Vol 3 (2) ◽

pp. 08-13

Author(s):

Ervina Julien Sitanggang

Keyword(s):

Blood Pressure ◽

Cardiovascular Disease ◽

Young Adults ◽

Blood Glucose ◽

Waist Circumference ◽

Blood Sugar ◽

Fasting Blood Glucose ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Sugar Levels

Introduction: Cardiovascular disease is the number one cause of death globally with an incidence of adolescents and young adults in Indonesia as many as 153.705 cases. Central obesity is associated with the risk of cardiovascular disease due to increase in fasting blood glucose levels, cholesterol and triglyceride levels, and blood pressure. Aims: to determine the correlation between waist circumference and fasting blood glucose levels, triglyceride levels, and blood pressure in young adults. Method: This analytic study with a cross-sectional approach involved 53 young adult subjects (18-25 years old). Waist circumference is measured using a tape measure. Blood sugar and triglyceride levels were measured using Cobas® 6000 analyzer machine from blood samples of subjects after fasting for 8-12 hours. Blood pressure data are obtained by measurement using aneroid sphygmomanometer. Results: In this study, the mean waist circumference of the research subjects was 77,4 cm. No correlation was found between waist circumference and fasting blood sugar levels (p = 0,159). However, a positive correlation was found between waist circumference and triglyceride levels (p = 0,008; r = 0,332), between waist circumference and systolic blood pressure (p = 0,049; r = 0,230), and between waist circumference and diastolic blood pressure (p = 0,017; r = 0,293). Conclusion: waist circumference is positively correlated with triglyceride levels and blood pressure, but does not correlate with fasting blood sugar levels.

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