No Association between Elevated 2-h Postprandial Blood Glucose Levels and Functional Outcomes of Small-Artery Occlusion in Patients with Diabetes

ABSTRAK Diabetes Melitus merupakan penyakit yang paling menonjol yang disebabkan oleh gagalnya pengaturan gula darah. Lidah buaya berkhasiat untuk menurunkan kadar gula dalam darah bagi penderita diabetes dan dapat mengontrol tekanan darah. Tujuan penelitian untuk mengetahui pengaruh jus lidah buaya (AloeBarbadensis Miller) terhadap penurunan glukosa darah puasa GDP) dan 2 Jam PP (Post Prendial) pada penderita DM (Diabetes Melitus). Desain penelitian merupakan Quasi Eksperimental dengan pendekatan one group pretest – postest design. Sampel terbagi menjadi 14 responden. Data dianalisis dengan paired t-test. Hasil menunjukan rata-rata penurunan glukosa darah puasa pada intervensi (28,42 gr/dl) dan glukosa darah 2 jam pp pada intervensi (40,57 gr/dl). Untuk analisis bivariat terdapat perbedaan antara glukosa puasa dan 2 jam pp dengan glukosa darah puasa GDP) dan 2 Jam PP (Post Prendial) pada penderita DM (Diabetes Melitus). Kesimpulan didapatkanlidah buaya dapat menurunkan kadar glukosa darah.Berdasarkan hasil penelitian jus lidah buaya dapat menjadi salah satu alternatif keperawatan non farmakologi dalam penyakit diabetes melitus. Kata Kunci : Lidah Buaya ; Diabetes Mellitus THE EFFECT OF VEGETABLE VOCATIONAL JUICE ON FAST BLOOD GLUCOSE LEVELS AND 2 HOURS OF PP (Post Prandial) IN DIABETES MELLITUS ABSTRACT Diabetes mellitus is the most prominent disease caused by the failure of blood sugar regulation. Aloe vera is efficacious can to reduce blood sugar levels for diabetics and can control blood pressure. The purpose of this study was to determine the effect of Aloe Barbadensis Miller on the reduction of fasting blood glucose GDP and 2 hours of PP (post prendial) in patients with diabetes mellitus. The research design is Experimental Quasi with one group pretest - postest design approach. The sample is divided into 14 respondents. Data were analyzed by paired t-test. The results showed an average decrease in fasting blood glucose at intervention (28.42 gr / dl) and 2 hours pp blood glucose at intervention (40.57 gr / dl). For bivariate analysis there was a difference between fasting glucose and 2 hours pp with fasting blood glucose GDP) and 2 hours PP (Post Prendial) in patients with diabetes mellitus. The conclusion is that aloe vera can reduce blood glucose levels. Based on the results of research on aloe vera juice can be an alternative non-pharmacological nursing in diabetes mellitus. Keywords: Aloe Vera ; Diabetes Mellitus

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Effect of meal composition on postprandial blood glucose levels in middle aged and young adults (1107.6)

The FASEB Journal ◽

10.1096/fasebj.28.1_supplement.1107.6 ◽

2014 ◽

Vol 28 (S1) ◽

Author(s):

Carynn Koch ◽

Jennifer Koch ◽

Mari Hopper

Keyword(s):

Young Adults ◽

Blood Glucose ◽

Postprandial Blood Glucose ◽

Middle Aged ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Meal Composition

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TYPE 2 DIABETES MELLITUS;

The Professional Medical Journal ◽

10.29309/tpmj/2014.21.05.2553 ◽

2018 ◽

Vol 21 (05) ◽

pp. 1005-1014

Author(s):

Jamil A. Malik ◽

Tuba Mumtaz ◽

Samsaam Ali Haider

Keyword(s):

Blood Glucose ◽

Emotional Problem ◽

Emotional Problems ◽

Treatment Modalities ◽

Routine Practice ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Obese Class ◽

Patients With Diabetes ◽

Effective Instrument

Objectives: The study is aimed to assess emotional problem of patients with Type2diabetes by translating and validating PAID. Associations between PAID and blood glucoselevels, and differences in prevalence of emotional problems across treatment modalities andBMI. Data Sources: Data was collected from various outpatients of Rawalpindi and Islamabad.Sample and Procedure: The sample of study comprised of 300 patients with diabetes bothmale = 135 (45%) and female n=165 (55%). Formal approval was taken from authorities atrespective hospitals and after taking informed consent patients were interviewed. Period:Data collection was completed during Feb to April, 2013. Material and Method: Patients wereasked to fill in demographic sheet along with Translated PAID scale. Latest blood glucose levelswere collected from their medical records whereas BMI was calculated by measuring patients’weight and height. Results: Results showed that emotional problems as assessed by PAID arepositively correlated with blood glucose levels (r=.12 to r=.19, p<.05). Additionally, patientswith IV modality of treatment (i.e., taking insulin shots) suffered significantly high (MD=4.88,p=.01) from emotional problems and patients with normal BMI and Obese Class-II have are athigher risk of emotional problem. Finally, patients rated serious concerns on diabetes-relatedissues like lifelong maintenance, future complications, depression and anxiety, and satisfactionwith physician. Conclusions: PAID is a very effective instrument in identifying emotionalproblems of diabetes patients related to adherence and compliance to their treatment regimeand hence it shall be used by physicians and health professional in routine practice.

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Prototypes of User Interfaces for Mobile Applications for Patients with Diabetes

Computers ◽

10.3390/computers8010001 ◽

2018 ◽

Vol 8 (1) ◽

pp. 1 ◽

Cited By ~ 2

Author(s):

Jan Pavlas ◽

Ondrej Krejcar ◽

Petra Maresova ◽

Ali Selamat

Keyword(s):

Blood Glucose ◽

User Interfaces ◽

Mobile Applications ◽

Eating Habits ◽

Relevant Literature ◽

Optimal Solution ◽

Glucose Levels ◽

Current State ◽

Blood Glucose Levels ◽

Patients With Diabetes

We live in a heavily technologized global society. It is therefore not surprising that efforts are being made to integrate current information technology into the treatment of diabetes mellitus. This paper is dedicated to improving the treatment of this disease through the use of well-designed mobile applications. Our analysis of relevant literature sources and existing solutions has revealed that the current state of mobile applications for diabetics is unsatisfactory. These limitations relate both to the content and the Graphical User Interface (GUI) of existing applications. Following the analysis of relevant studies, there are four key elements that a diabetes mobile application should contain. These elements are: (1) blood glucose levels monitoring; (2) effective treatment; (3) proper eating habits; and (4) physical activity. As the next step in this study, three prototypes of new mobile applications were designed. Each of the prototypes represents one group of applications according to a set of given rules. The most optimal solution based on the users’ preferences was determined by using a questionnaire survey conducted with a sample of 30 respondents participating in a questionnaire after providing their informed consent. The age of participants was from 15 until 30 years old, where gender was split to 13 males and 17 females. As a result of this study, the specifications of the proposed application were identified, which aims to respond to the findings discovered in the analytical part of the study, and to eliminate the limitations of the current solutions. All of the respondents expressed preference for an application that includes not only the key functions, but a number of additional functions, namely synchronization with one of the external devices for measuring blood glucose levels, while five-sixths of them found suggested additional functions as being sufficient.

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Effects of Various Blending Ratios of Rice and Waxy Barley on Postprandial Blood Glucose Levels

Nippon Eiyo Shokuryo Gakkaishi ◽

10.4327/jsnfs.71.283 ◽

2018 ◽

Vol 71 (6) ◽

pp. 283-288

Author(s):

Seiichiro Aoe ◽

Kozo Komae ◽

Yutaka Inoue ◽

Isamu Murata ◽

Yuki Minegishi ◽

...

Keyword(s):

Blood Glucose ◽

Postprandial Blood Glucose ◽

Glucose Levels ◽

Blood Glucose Levels

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EFFECT OF AEROBIC EXERCISES AND RESISTANCE TRAINING ON GLUCOSE LEVELS IN TYPE 2 DIABETIC SUBJECTS.

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2017.v10i7.18532 ◽

2017 ◽

Vol 10 (7) ◽

pp. 360

Author(s):

Aishwarya Pramod Benkar ◽

Smita Bhimrao Kanase

Keyword(s):

Diabetes Mellitus ◽

Blood Glucose ◽

Resistance Training ◽

Blood Glucose Level ◽

Glucose Level ◽

Postprandial Blood Glucose ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Significant Difference

Objective: Diabetes mellitus is a leading cause of death and disability in the world and its prevalence is predicted to rise to 10% by 2030. Hence, this study is conducted with objectives to find out the effect of aerobic exercises and resisted exercises on blood glucose levels in type 2 diabetes mellitus (T2DM) subjects and to compare the effect of both exercises on blood glucose level.Method: The comparative study was conducted at Krishna Institute of Medical Sciences Deemed University, Physiotherapy department, Karad. 30 participants with age group between 30 and 65 years were taken. Subjects were selected as per inclusion and exclusion criteria. Group A (15) participants were given aerobic exercise on static bicycle, and Group B (15) participants were given resistance training using dumbbells and weight cuffs for 5 days/week for 4 weeks. Diet recommendations were given to every participant.Results: Statistical analysis was performed using paired and unpaired t-test. Analysis showed statistically extremely significant difference in fasting blood glucose level and postprandial blood glucose level in both the groups (p≤0.0001).Conclusion: Thus, this study concludes that both aerobic exercises and resistance training prove to be beneficial in controlling blood glucose levels in T2DM subjects.

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Effects of metformin, acarbose, and sitagliptin monotherapy on gut microbiota in Zucker diabetic fatty rats

BMJ Open Diabetes Research & Care ◽

10.1136/bmjdrc-2019-000717 ◽

2019 ◽

Vol 7 (1) ◽

pp. e000717 ◽

Cited By ~ 10

Author(s):

Minchun Zhang ◽

Rilu Feng ◽

Mei Yang ◽

Cheng Qian ◽

Zheng Wang ◽

...

Keyword(s):

Blood Glucose ◽

Gut Microbiota ◽

Relative Abundance ◽

16S Rrna Gene Sequencing ◽

Postprandial Blood Glucose ◽

Saline Control ◽

Rrna Gene ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Zucker Diabetic Fatty Rats

ObjectiveRecent studies have demonstrated that gut microbiota was closely related to metabolic disorders such as type 2 diabetes. Oral antidiabetic medications including metformin, acarbose and sitagliptin lowered blood glucose levels via acting on the gastrointestinal tract. The aim of the study was to observe the comparisons among those medications on gut microbiota composition.Research design and methodsZucker diabetic fatty rats (n=32) were randomly divided into four groups, and had respectively gastric administration of normal saline (control), metformin (215.15 mg/kg/day), acarbose (32.27 mg/kg/day), or sitagliptin (10.76 mg/kg/day) for 4 weeks. Blood glucose levels were measured during an intragastric starch tolerance test after the treatments. 16S rRNA gene sequencing was used to access the microbiota in the fecal samples.ResultsMetformin, acarbose, and sitagliptin monotherapy effectively decreased fasting and postprandial blood glucose levels (p<0.001). Acarbose group displayed specific cluster and enterotype mainly composed byRuminococcus 2whileLactobacilluswas the dominant bacterium in the enterotype of the other three groups. The relative abundance of generaRuminococcus 2andBifidobacteriumwas dramatically higher in acarbose group. Metformin and sitagliptin increased the relative abundance of genus Lactobacillus. Metagenomic prediction showed that the functional profiles of carbohydrate metabolism were enriched in acarbose group.ConclusionsMetformin, acarbose and sitagliptin exerted different effects on the composition of gut microbiota and selectively increased the beneficial bacteria. Supplementation with specific probiotics may further improve the hypoglycemic effects of the antidiabetic drugs.

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Effectiveness of acarbose in treating elderly patients with diabetes with postprandial hypotension

Journal of Investigative Medicine ◽

10.1136/jim-2016-000295 ◽

2017 ◽

Vol 65 (4) ◽

pp. 772-783 ◽

Cited By ~ 5

Author(s):

Jie Zhang ◽

Lixin Guo

Keyword(s):

Blood Pressure ◽

Blood Glucose ◽

Elderly Patients ◽

Controlled Trial ◽

Clinical Trial Registry ◽

Postprandial Hypotension ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Patients With Diabetes ◽

Group B

Postprandial hypotension (PPH) is a common condition that occurs primarily in elderly patients with type 2 diabetes mellitus (T2DM). This study aimed to assess the effectiveness of acarbose for PPH; it also investigated possible mechanisms behind PPH development. This single-blind, randomized controlled trial included 91 elderly patients with T2DM, aged between 60 and 80 years, who were inpatients at Beijing Hospital between March 2012 and November 2014. The patients were included into one of three groups: Group A, patients with T2DM without PPH; Group B, patients with T2DM with PPH receiving placebo; and Group C, patients with T2DM with PPH receiving acarbose. After an overnight fast, patients received a single dose of acarbose (100 mg) or placebo and then consumed a standardized 450 kcal meal. Blood pressure, glucose levels, heart rate (HR), and catecholamine levels were evaluated. Acarbose ameliorated PPH as determined by significant improvements in the duration and maximal fall in blood pressure (both p<0.001); however, no differences in HR and blood glucose levels were observed. In patients with PPH, blood pressure was correlated with blood glucose and HR variability values (p<0.05). Correlations between epinephrine and glucagon-like peptide-1 with blood pressure in groups A and C were largely lost in group B. Acarbose reduced postprandial blood pressure fluctuations in elderly patients with diabetes. PPH may be related to impaired autonomic nervous system function, reduced catecholamine secretion, and postprandial fluctuations in blood glucose levels.Trial registration numberChinese Clinical Trial Registry ChiCTR-IPR-15006177.

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