INFLUENCE OF AGE AND APACHE II ON OUTCOME IN SEVERE SEPSIS RECEIVING DROTRECOGIN ALFA (XIGRIS) IN A RURAL TERTIARY CARE HOSPITAL

2004 ◽  
Vol 32 (Supplement) ◽  
pp. A152
Author(s):  
richard L mcknight ◽  
Harakh V dedhia ◽  
frank G schiebel
2021 ◽  
Vol 38 (1) ◽  
Author(s):  
Farheen Yousuf ◽  
Ayesha Malik ◽  
Ayesha Saba ◽  
Sana Sheikh

Background and Objective: Sepsis is one of the leading causes of direct maternal mortality in Pakistan. It is recommended that the first three hours after the presentation are crucial. During this time implementation of surviving sepsis campaign resuscitation bundles reduces maternal mortality. Our objective was to assess the factors contributing to puerperal sepsis and the compliance of “surviving sepsis campaign resuscitation bundles in puerperal sepsis” for the management of puerperal sepsis. Methods: This was a retrospective record review for five years from January 2011-December 2015. All women who fulfilled the inclusion criteria of puerperal sepsis were included and data from their files were collected and entered in SPSS version 19.0. Mean and standard deviations were calculated for continuous variables while for categorical variable proportion and percentages were used. Results: This retrospective record review in five years showed the 396 patients had P-sepsis, among them 44 patients had severe sepsis with organ dysfunction. The culture was positive in 26(59%) with trend of E-coli in 9(20%) Among them 12(27%) had serum lactate more than ≥4mmol/L. Central venous pressure monitoring with fluid resuscitation was done as per protocol of survival bundle given to all 12(100%), Vasopressin was needed in half of these patients 6(50%). Amid 44 patients of severe sepsis 29(66%) were admitted to special care, while 15(34%) required intensive care admissions. Our 7(16%) patients failed to survive. All of them had multi-organ failure. Conclusion: There was moderate adherence of modified surviving sepsis campaign resuscitation bundles. Further improvement in compliance is warranted. doi: https://doi.org/10.12669/pjms.38.1.3992 How to cite this:Yousuf F, Malik A, Saba A, Sheikh S. Risk factors and Compliance of surviving sepsis campaign: A retrospective cohort study at tertiary care hospital. Pak J Med Sci. 2022;38(1):---------. doi: https://doi.org/10.12669/pjms.38.1.3992 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2017 ◽  
Vol 4 (29) ◽  
pp. 1700-1704 ◽  
Author(s):  
Deepak Chaudhury ◽  
Subhankar Paul ◽  
Chandraprakash Chandraprakash ◽  
Ilias ali

2018 ◽  
Vol 5 (6) ◽  
pp. 1347
Author(s):  
Ramesh Babu Pannem ◽  
Chandra Sekara Reddy Munamala

Background: Magnesium is the fourth abundant cation in the human body and second most abundant intracellular cation after potassium and also serving as cofactor in more than 300 enzymatic reactions. Magnesium deficiency is the most commonly overlooked condition in critically ill patients and associated with other coexisting electrolyte abnormalities. The aim of the present study was to evaluate serum magnesium levels in critically ill patients and to correlate with patient outcome and other parameters like length of stay in ICU, ventilator support, APACHE-II score and duration and mortality.Methods: A two years observational study after ethical committee approval was conducted at a tertiary care hospital among critically ill patients admitted in ICU. Serum magnesium levels and other relevant investigations were performed within 24 hours of admission. Patients management and progress were followed till the outcome. The data was analysed by using SPSS software version 16.0 for windows.Results: Total of 150 patients with 102 males and 48 females were enrolled. 97 cases (64.7%) of hypomagnesemia were observed and 11 cases of hypermagnesemia and 42 cases with normal serum magnesium levels were observed. Hypomagnesemia cases were compared with normal cases and found that: Hypomagnesemia cases had higher mortality rate, higher APACHE II score, more length of hospital stay and ventilator duration. Significant association was identified with diabetes and chronic alcoholism (p valve <0.05).Conclusions: Monitoring of magnesium levels in critically ill patients has several prognostic and therapeutic implications and should be recommended as a regular parameter as it is commonly out looked condition. Statistically significant association of hypomagnesaemia was found with hypocalcaemia, hypoalbuminaemia, septicaemia, diabetes and chronic alcoholism. Higher APACHE II score is associated with higher mortality and more length of stay in ICU among the cases of hypomagnesaemia.


2016 ◽  
Vol 34 (6) ◽  
pp. 1117-1120 ◽  
Author(s):  
Denise McCormack ◽  
Avi Ruderman ◽  
William Menges ◽  
Miriam Kulkarni ◽  
Tiffany Murano ◽  
...  

Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  

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