COGNITIVE FUNCTION IN HYPERTENSIVE PATIENTS WITH OR WHITHOUT OTHER RISK FACTORS ASSOCIATED

The prevalence of dementia has substantially increased worldwide. Currently, there is no cure for dementia or Alzheimer’s disease (AD), and care for affected patients is financially and psychologically costly. Of late, more attention has been given to preventive interventions—in particular, physical activity/exercise. In this review, examine the risk factors associated with AD and the effects physical activity may play in the prevention of the degenerative process of this disease, loss of memory and cognitive performance in the elderly. To date, research has shown that physical activity, especially aerobic exercise, has a protective effect on cognitive function and memory in the elderly and Alzheimer’s patients. In comparison with aerobic exercise, several strength training studies have also shown positive effects, and the rare studies that compare the two different modalities show no difference.

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Additional risk factors associated with symptomatic hydrochlorothiazide-induced hyponatremia in hypertensive patients

Arterial Hypertension ◽

10.5603/ah.a2020.0003 ◽

2020 ◽

Vol 24 (1) ◽

pp. 16-21

Author(s):

Paiboon Chattakul ◽

Panuwat Napinkul ◽

Sittichai Khamsai ◽

Panita Limpawattana ◽

Jarin Chindaprasirt ◽

...

Keyword(s):

Risk Factors ◽

Additional Risk ◽

Hypertensive Patients ◽

Factors Associated

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Hyperhomocysteinemia is one of the risk factors associated with cerebrovascular stiffness in hypertensive patients, especially elderly males

Scientific Reports ◽

10.1038/srep05663 ◽

2014 ◽

Vol 4 (1) ◽

Cited By ~ 31

Author(s):

Takafumi Okura ◽

Ken-ichi Miyoshi ◽

Jun Irita ◽

Daijiro Enomoto ◽

Tomoaki Nagao ◽

...

Keyword(s):

Risk Factors ◽

Hypertensive Patients ◽

Factors Associated ◽

Elderly Males

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A study to evaluate risk factors and factors associated with non-adherence to the prescribed treatment among essential hypertensive patients attending tertiary care hospital

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20203933 ◽

2020 ◽

Vol 7 (9) ◽

pp. 3623

Author(s):

Venkat Sunil Bommishetty ◽

Suresh Keshav Kumbhar

Keyword(s):

Risk Factors ◽

Medication Adherence ◽

Life Style ◽

Tertiary Care ◽

Positive Family History ◽

Cross Sectional Study ◽

Care Hospital ◽

Cross Sectional ◽

Hypertensive Patients ◽

Factors Associated

Background: Prevalence of hypertension is on rising trend with rise in life style and behavioral changes. It is also a major risk factor for most of the dreadful conditions like coronary artery disease, stroke, etc. Medication adherence would help in reducing the chance of occurrence of such complications. Thus objectives of study are 1) to evaluate the risk factors of hypertension among the diagnosed essential hypertensive patients; and 2) to assess the magnitude and the factors associated with non-adherence to the prescribed treatment.Methods: A hospital based cross-sectional study among 71 participants was conducted, using a pre-structured questionnaire and physical examination to assess risk factors of hypertension and CULIG’s 16 questionnaire medication adherence scale to assess the non-adherence. Data analysed with proportions and Chi square test.Results: Out of 71 participants, 60 (84.5%) were found to be non-adherent to their anti-hypertensive medication and factors like being male (p=0.0055), alcohol consumption (p=0.0485) and paid medication (p=0.0091) were found to be significantly affecting the medication non-adherence. Positive family history, sedentary life style, preference of extra salt and smoking/tobacco products usage were the most common risk factors of essential hypertension observed along with others.Conclusions: The participants who experienced the complications/ill effects of hypertension were more adherent as compared to others. Factors which are responsible for non -adherence need to be addressed and appropriate interventions required to improve adherence by educating the people about its importance in prevention of complications.

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Determination of clinical risk factors associated with inflammation in hypertensive patients with type-2 diabetes mellitus

10.1101/613711 ◽

2019 ◽

Author(s):

Mohammed S. Ellulu

Keyword(s):

Physical Activity ◽

Diabetes Mellitus ◽

Risk Factors ◽

Diabetic Patients ◽

Physically Active ◽

Hypertensive Patients ◽

Factors Associated ◽

Hs Crp ◽

Active Patients

ABSTRACTBackgroundObesity and chronic diseases associated with the development of inflammation have remained unclear if the observed inflammatory state in diabetic patients is due to excess adipose tissue mass and/or directly associated with the diabetic state. Therefore, this study determined the risk factors associated with inflammation in hypertensive patients with type-2 diabetes mellitus.MethodsA total of 164 hypertensive diabetic patients aged 38 to 60 years were selected from seven primary health care centers in Gaza city, Palestine. Interview and questionnaire were employed to collect data related to age, gender, smoking habits, and physical activity pattern. Besides, the selection of patients depended on objective criteria.ResultsThe study involved 118 (72%) women and 46 (28%) men. The mean of age for all patients was 53.7±0.46 years old. 76 patients (46.3%) were categorized as current smokers, 88 patients (53.7%) categorized as non-smokers. The baseline distribution of patients according to physical activity has displayed that 130 (79.3%) were low physically active patients, 28 (27.1%) were moderate, and 6 (3.7%) were highly physically active patients. A tertile of inflammation feature with high sensitivity C-reactive protein (hs-CRP) was developed. The highest tertile of hs-CRP was significantly associated with women, higher obesity indices, metabolic dysregulation involving lipid profile markers, fasting blood glucose (FBG) and blood pressure, higher interleukin 6 (IL-6), and lower adiponectin. Via ordinal logistic regression analysis, after adjusting for age, gender, smoking habits, and physical activity; the risk factors for hs-CRP were the increased body mass index [OR: 1.17, P=0.018], IL-6 [OR: 2.22, P=0.025] and FBG [OR: 1.01, P=0.007], as well as reduced adiponectin [OR: 0.81, P=0.002].ConclusionThe inflammation state was affected by obesity and had been related to altered adipokines levels of IL-6 and adiponectin, as well as affected by the disease condition of diabetes, as evidenced by higher serum level of FBG.

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Factors associated with high brachial–ankle pulse wave velocity in non-hypertensive and appropriately treated hypertensive patients with atherosclerotic risk factors

Vascular Health and Risk Management ◽

10.2147/vhrm.s144923 ◽

2017 ◽

Vol Volume 13 ◽

pp. 383-392 ◽

Cited By ~ 1

Author(s):

Dai Ato ◽

Toshitami Sawayama

Keyword(s):

Risk Factors ◽

Pulse Wave Velocity ◽

Wave Velocity ◽

Pulse Wave ◽

Hypertensive Patients ◽

Factors Associated ◽

Atherosclerotic Risk Factors

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Factors associated with head circumference and indices of cognitive development in early childhood

BMJ Global Health ◽

10.1136/bmjgh-2020-003427 ◽

2020 ◽

Vol 5 (10) ◽

pp. e003427

Author(s):

Laura Nicolaou ◽

Tahmeed Ahmed ◽

Zulfiqar Ahmed Bhutta ◽

Pascal Bessong ◽

Margaret Kosek ◽

...

Keyword(s):

Risk Factors ◽

Cognitive Function ◽

Cognitive Development ◽

Head Circumference ◽

Brain Size ◽

Birth Cohort Study ◽

Intracranial Volume ◽

Z Score ◽

Gross Motor ◽

Factors Associated

BackgroundWhile head circumference (HC) has been related to intracranial volume and brain size, its association with cognitive function remains unclear. We sought to understand the relationship among various biological and socioeconomic risk factors, HC and cognitive development.MethodsWe analysed data across resource-poor settings in Bangladesh, India, Nepal, Peru, South Africa and Tanzania from the Etiology, Risk Factors and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development longitudinal birth cohort study. Participating children were enrolled and followed up between 2009 and 2014. A final sample of 1210 children aged 0–24 months were included in the analyses. The main outcomes were HC for age Z-score and cognitive, gross motor and language scores from Bayley Scales of Infant Development-III tests. Length, weight and HC were measured monthly, and cognitive tests were administered at 6, 15 and 24 months of age. To disentangle the associations between risk factors and HC from linear growth and to distinguish the direct and indirect effects of these risk factors on cognitive function, we conducted mediation analysis using longitudinal models to account for all data measured during follow-up.ResultsAverage HC-for-age Z-score (HCAZ) was −0.54 (95% CI −0.47 to −0.62) near birth and −1.01 (95% CI −0.94 to −1.08) at 24 months. Children with higher enrolment weight (p<0.0001), higher socioeconomic score (p=0.00037) and taller mothers (p=0.00084) had higher HCAZ at all ages, while enteropathogen infection (p=0.013) and more febrile episodes (p=0.013) were associated with lower HCAZ. The associations between HCAZ and enrolment weight-for-age, maternal height, socioeconomic status or pathogen burden were partly mediated through their associations with length-for-age. HCAZ showed no association with cognitive, gross motor or language skills at 6, 15 and 24 months of age.ConclusionsThe main risk factors associated with HC are similar to those associated with body length, and HC is not related to cognitive function.

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