The comparison of different medical treatment modalities in pes anserinus tendino-bursitis

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Mehmet Yalcinozan ◽  
Deniz Aydin ◽  
Enes Sari
Keyword(s):  
Medical Treatment ◽  
Treatment Modalities ◽  
Pes Anserinus

scholarly journals Is it possible to estimate the need for surgical management in patients with a tubo-ovarian abscess at admission? A retrospective long-term analysis

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Murat Gözüküçük ◽  
Esra Gülen Yıldız
Keyword(s):  
Surgical Treatment ◽  
Antibiotic Therapy ◽  
Treatment Failure ◽  
Medical Treatment ◽  
Length Of Hospital Stay ◽  
Treatment Modalities ◽  
Laboratory Findings ◽  
Factors Affecting ◽  
Laboratory Infection ◽  
Major Factors

Abstract Background This study aimed to determine the possible prognostic factors correlated with the treatment modalities of tubo-ovarian abscesses (TOAs) and thus to assess whether the need for surgery was predictable at the time of initial admission. Materials and methods Between January 2012 and December 2019, patients who were hospitalized with a TOA in our clinic were retrospectively recruited. The age of the patients, clinical and sonographic presentation, pelvic inflammatory risk factors, antibiotic therapy, applied surgical treatment, laboratory infection parameters, and length of hospital stay were recorded. Results The records of 115 patients hospitalized with a prediagnosis of TOA were reviewed for the current study. After hospitalization, TOA was ruled out in 19 patients, and data regarding 96 patients was included for analysis. Twenty-eight (29.2%) patients underwent surgical treatment due to failed antibiotic therapy. Sixty-eight (70.8%) were successfully treated with parenteral antibiotics. Medical treatment failure and need for surgery were more common in patients with a large abscess (volume, > 40 cm3, or diameter, > 5 cm). The group treated by surgical intervention was statistically older than the patients receiving medical treatment (p < 0.05). Conclusions Although the treatment in TOA may vary according to clinical, sonographic, and laboratory findings; age of patients, the abscess size, and volume were seen as the major factors affecting medical treatment failure. Moreover, TOA treatment should be planned on a more individual basis.

Quality of Life and its Determinants in Patients With Treated Acromegaly: A Cross-Sectional Nationwide Study in China

2020 ◽  
Vol 106 (1) ◽  
pp. 211-225
Author(s):  
Xiaopeng Guo ◽  
Kailu Wang ◽  
Siyue Yu ◽  
Lu Gao ◽  
Zihao Wang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Medical Treatment ◽  
Short Form ◽  
Somatostatin Analogs ◽  
Chinese Patients ◽  
Treatment Modalities ◽  
Biochemical Control ◽  
Cross Sectional

Abstract Context Quality of life (QoL) continues to be impaired in acromegaly after treatment. Objective We conducted the first nationwide survey assessing QoL status among Chinese patients with treated acromegaly and explored correlations with clinical parameters, treatment modalities, and outcomes. Design Cross-sectional study. Setting Survey via Chinese Association of Patients with Acromegaly (CAPA) online platform. Patients Treated patients from CAPA. Main Outcome Measures QoL was assessed using acromegaly QoL questionnaire (AcroQoL), 5-level EuroQoL five-dimensional questionnaire (EQ-5D-5L), and 12-item short-form health survey questionnaire (SF-12). Results Complete, valid questionnaires from 327 patients (mean age: 39.2 years, 61.5% females) at a mean of 10 years after treatment were included. Biochemical control was satisfied in 52.9% of these patients. The controlled patients had significantly better QoL than the uncontrolled patients in all AcroQoL dimensions, most SF-12 dimensions, and pain/discomfort and anxiety/depression dimensions of the EQ-5D-5L. Patients with either controlled or uncontrolled acromegaly had significantly worse QoL than the age- and sex-adjusted population reference in most SF-12 dimensions except for physical functioning. More acromegaly-associated symptoms and comorbidities at follow-up were independent risk factors for decreased QoL across all questionnaires. Medical treatment, especially with somatostatin analogs (SSAs), and radiotherapy were predictors of worse QoL. Female patients had lower scores of physical-related QoL than male patients. Conclusions Our study suggests that biochemical control improved but did not normalize QoL in acromegaly. Numbers of symptoms and comorbidities at follow-up, sex, radiotherapy, and medical treatment with SSAs were factors determining QoL of patients with treated acromegaly.

scholarly journals Emphysematous pyelonephritis: Our experience in managing these cases

2015 ◽  
Vol 9 (7-8) ◽  
pp. 480 ◽  
Author(s):  
Fatih Uruc ◽  
Ozgur Haki Yuksel ◽  
Aytac Sahin ◽  
Ahmet Urkmez ◽  
Caglar Yildirim ◽  
...  
Keyword(s):  
Medical Treatment ◽  
Clinical Laboratory ◽  
Treatment Strategies ◽  
Renal Stones ◽  
Treatment Modalities ◽  
Diabetic Patients ◽  
Health State ◽  
Emphysematous Pyelonephritis ◽  
Klebsiella Species ◽  
Cell Counts

Introduction: Emphysematous pyelonephritis (EPN) is a rare acute necrotising infection of renal parenchyma. We discuss clinical details and treatment strategies of 8 patients with EPN followed at our clinic.Methods: We retrospectively reviewed the clinical, laboratory, radiological findings and treatment modalities of 8 patients with EPN followed at our urology clinic between 2012 and 2015.Results: The mean patient age (female: 5; male: 3) was 62 (range: 51–82) years. Based on computed tomographic findings, EPN was classified as class 1 (n = 3), class 2 (n = 3) and class 3a (n = 2). All patients had fever, flank pain, nausea, and vomiting. Five patients had type 2 diabetes mellitus and 3 diabetic patients also had renal stones. Escherichia coli (n = 6), Klebsiella species (n = 1), and Proteus species (n = 1) were grown in urine cultures. All patients had unilateral involvement. Increased white blood cell counts, sedimentation rate, and C-reactive protein levels were detected in all cases. In addition to medical treatment, 2 patients underwent a nephrostomy catheter placement and another 2 patients underwent nephrectomy upon deterioration of her general health state. After achieving clinical stabilization with medical treatment, 1 patient underwent endoscopic ureteral stone treatment. The remaining 3 cases were treated only with antibiotherapy. All patients were discharged with clinical cure.Conclusion: Mortality rates of EPN are gradually decreasing. Preservation of renal reserve is possible due to early diagnosis, appropriate antibiotherapy, and drainage.

scholarly journals New developments in the medical treatment of Cushing's syndrome

2012 ◽  
Vol 19 (6) ◽  
pp. R205-R223 ◽  
Author(s):  
R van der Pas ◽  
W W de Herder ◽  
L J Hofland ◽  
R A Feelders
Keyword(s):  
Medical Treatment ◽  
Medical Therapy ◽  
Cushing’S Syndrome ◽  
Treatment Options ◽  
Cushing's Syndrome ◽  
Treatment Modalities ◽  
Primary Therapy ◽  
Ectopic Acth ◽  
Considerable Morbidity ◽  
Acth Secreting

Cushing's syndrome (CS) is a severe endocrine disorder characterized by chronic cortisol excess due to an ACTH-secreting pituitary adenoma, ectopic ACTH production, or a cortisol-producing adrenal neoplasia. Regardless of the underlying cause, untreated CS is associated with considerable morbidity and mortality. Surgery is the primary therapy for all causes of CS, but surgical failure and ineligibility of the patient to undergo surgery necessitate alternative treatment modalities. The role of medical therapy in CS has been limited because of lack of efficacy or intolerability. In recent years, however, new targets for medical therapy have been identified, both at the level of the pituitary gland (e.g. somatostatin, dopamine, and epidermal growth factor receptors) and the adrenal gland (ectopically expressed receptors in ACTH-independent macronodular adrenal hyperplasia). In this review, results of preclinical and clinical studies with drugs that exert their action through these molecular targets, as well as already established medical treatment options, will be discussed.

scholarly journals Diagnosis and Treatment Approaches in Infantile Colic (IC): Results of a Survey Among Paediatricians in Turkey

2021 ◽  
Vol 9 ◽  
Author(s):  
Samil Hizli ◽  
Demet Can ◽  
Ilknur Kiliç ◽  
Emel Örün ◽  
Turan Tunç ◽  
...  
Keyword(s):  
Medical Treatment ◽  
Clinical Experience ◽  
The Other ◽  
Diagnosis And Treatment ◽  
Response To Treatment ◽  
Treatment Modalities ◽  
Treatment Preferences ◽  
Family Quality Of Life ◽  
Infantile Colic ◽  
Probiotic Treatment

Background and Objective: Due to limited knowledge on the etiopathogenesis of infantile colic (IC) and the insufficiency of data regarding current treatments, different approaches emerge in terms of diagnosis, and treatment modalities globally and also in Turkey. The objective of this study was to observe how infantile colic is diagnosed and treated by paediatricians in Turkey.Methods: An anonymous electronic questionnaire was used to collect the respondents' opinions. The study questionnaire was comprised of 4 different sections with 56 multiple-choice questions covering demographic features, diagnostic approach, treatment preferences and response to treatment.Results: A total of 375 paediatricians responded to the survey. Fifty three percent of the participants stated that they established the IC diagnosis based only on their clinical experience. Factors that most affected the decision to start treatment were identified as parent discomfort, decreased family quality of life, and crying duration (68, 66, and 54%, respectively). Application of soothing methods, probiotics, and simethicone were identified as the most frequently used treatment modalities (frequency ranking; 81, 76, and 50%, respectively). Of the participants, 98% stated that they used probiotic as supplements, on the other hand, 72% of the participants indicated that they used simethicone as the only medical treatment to treat IC. The question about the participants' observations regarding the response to probiotic treatment was answered by 71% of the participants with decreased crying duration, while easier stool/gas passage and resolved digestion problems were the other frequent observations (54 and 49%, respectively). The observations related to the response to simethicone treatment also included decreased crying duration in addition to decreased crying periods after feeding and easier gas/stool passage (67, 47, and 44%, respectively).Conclusions: Survey results revealed that the majority of the paediatricians used their clinical experience alone to establish the diagnosis of IC and preferred probiotic supplements and simethicone as the only medical treatment to treat IC and they observed clinical benefits from them. Insights generated by this study will be helpful to guide future efforts to improve the management of infantile colic by paediatricians.

scholarly journals Novel Medical Treatment Modalities of Endometriosis

2015 ◽  
Vol 5 (3) ◽  
pp. 109-119 ◽  
Author(s):  
Gulsum Uysal ◽  
Fulya Caglı ◽  
Huseyin Aksoy ◽  
Ulku Aksoy ◽  
Basak Cıngıllıoglu ◽  
...  
Keyword(s):  
Medical Treatment ◽  
Treatment Modalities

scholarly journals Lifestyle modification and medical treatment of long QT syndrome

2021 ◽  
Vol 8 (9) ◽  
pp. 4637
Author(s):  
Omar Rezk Alshaer ◽  
Abdullah Obaid Binobaid ◽  
Saeed Dawas Alwadai ◽  
Wejdan Hani Alhakeem ◽  
Khalid Abdullah Al-Attas ◽  
...  
Keyword(s):  
Medical Treatment ◽  
Long Qt Syndrome ◽  
Lifestyle Modification ◽  
Maximum Dose ◽  
Treatment Modalities ◽  
Lifestyle Modifications ◽  
Long Qt ◽  
Icd Implantation ◽  
Cardioverter Defibrillator ◽  
Qt Syndrome

Studies have shown that many manifestations can be observed for patients suffering from long QT syndrome (LQTS), as it is a common cause of syncope and mortality among younger patients, in addition to convulsions. Many management modalities for LQTS have been described in the literature including medical treatment modalities and lifestyle modification approaches. However, evidence regarding the outcomes of these approaches is continuously updating. In this study, we have reviewed findings from the current studies in the literature about the medical treatment and lifestyle modifications for patients suffering from LQTS. Furthermore, studies have shown that β-blockers are effective modalities and should be used at a maximum dose. However, the potential side events should be considered and adequately managed and patient compliance should be maintained along the course of treatment. Implantable cardioverter-defibrillator (ICD) implantation and LCSD were also discussed in the present study with their favorable indications. Additionally, lifestyle modifications were also important and have been reported with favorable events and therefore, these should be considered in such situations. However, evidence regarding some approaches as limiting competitive exercises is still conflicting, indicating the need for future investigations.

Understanding Patients’ Attitudes Toward Cancer Multidisciplinary Meetings: A Mixed Methods Study

2020 ◽  
Vol 16 (2) ◽  
pp. e175-e182
Author(s):  
Bianca Devitt ◽  
Jennifer Philip ◽  
Madhu Singh ◽  
Sue-Anne McLachlan
Keyword(s):  
Mixed Methods ◽  
Medical Treatment ◽  
Treatment Plan ◽  
Quality Care ◽  
Treatment Modalities ◽  
Evidence Based ◽  
Theory Approach ◽  
Previous Diagnosis ◽  
Diagnosis Of Cancer ◽  
A Current

PURPOSE: Multidisciplinary cancer meetings (MDMs) are an integral component of quality care; however, little research exists regarding patients’ views on this model of care. We aimed to explore and understand the attitudes of patients toward MDMs. METHODS: A mixed methods exploratory design was used. Qualitative data from patients with a current or previous diagnosis of cancer were collected and analyzed using a grounded theory approach. Results informed the development of a questionnaire survey that was administered to patients with a current or previous diagnosis of cancer. Results were analyzed using descriptive statistics. RESULTS: Nine patients participated in 3 focus groups, and 152 patients (response rate, 90%) completed the questionnaire. Patients were strongly supportive of MDMs and thought that all patients with cancer should be routinely discussed. More than 90% of surveyed patients believed MDMs were reassuring, meant all treatment modalities were considered, and led to evidence-based treatment recommendations. Patients wanted MDMs to focus on medical treatment planning rather than psychosocial issues, and 87% regarded the meeting as confidential. Patients described a preference for doctor-led decision making, and most (84%) wanted MDM treatment decisions to be discussed with them in a subsequent consultation, with 73% of patients also wanting this in a written format. CONCLUSION: Patients strongly endorse MDMs as a means to develop an evidence-based, medical treatment plan agreed to by consensus. They want to be purposely informed of the meeting and its outcomes. Results from this study can help inform future guidelines on the conduct of MDMs.

scholarly journals Lumbar Epidural Abscesses: A Systematic Review

2018 ◽  
Vol 8 (4_suppl) ◽  
pp. 85S-95S ◽  
Author(s):  
Charles N. de Leeuw ◽  
Patrick R. Fann ◽  
Joseph E. Tanenbaum ◽  
Avery L. Buchholz ◽  
Brett A. Freedman ◽  
...  
Keyword(s):  
Systematic Review ◽  
Medical Treatment ◽  
Medical Management ◽  
Early Recognition ◽  
Severe Disease ◽  
Neurological Impairment ◽  
Treatment Modalities ◽  
Motor Deficit ◽  
Limited Information ◽  
Evidenced Based

Study Design: Systematic review. Objectives: Spinal epidural abscesses (SEAs) are rare, but when missed or when diagnosis is delayed, SEA can lead to permanent neurological impairment or death. Limited information exists on the optimal treatment modalities for SEA, especially in the lumbar spine. We synthesize the current literature to identify the clinical features, diagnosis, management, and outcomes of lumbar SEA. Methods: Queries in 4 databases—EMBASE, MEDLINE, Scopus, and Web of Science—were performed using comprehensive search terms to locate published literature on lumbar SEA. Results: Ten articles reporting results for 600 cases of lumbar SEA were included, published between 2000 and 2017. Negative prognostic factors included diabetes, older age, methicillin-resistant Staphylococcus aureus, immune compromise, and more severe disease at presentation. Early first-line surgically treated patients responded better, specifically in terms of motor recovery, than those undergoing medical management or failing medical treatment, despite generally worse initial presentation. Elevated C-reactive protein, leukocytosis, and positive blood cultures predicted medical management failure. Conclusions: This systematic review provides guidance to neurological and orthopedic spine surgeons seeking the best treatment for lumbar-localized SEA. This study is limited by a dearth of high-quality publications to support evidenced-based management recommendations. Surgical treatment appears to provide better outcomes than medical treatment alone, especially in those who present with a motor deficit. Further investigation is needed to confirm this finding. What is clear is that early recognition and treatment remains crucial to minimizing morbidity and mortality of SEA.

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