scholarly journals The effect of oral nutritional supplement therapy on nutritional status and quality of life in patients with esophageal cancer undergoing radiotherapy and chemotherapy

Medicine ◽  
2021 ◽  
Vol 100 (16) ◽  
pp. e25342
Author(s):  
Yunxia Chen ◽  
Xiancui Wu ◽  
Xiaowei Wei ◽  
Li Xu ◽  
Xiuqin Ren
Keyword(s):  
Quality Of Life ◽  
Esophageal Cancer ◽  
Nutritional Status ◽  
Nutritional Supplement ◽  
Oral Nutritional Supplement ◽  
Supplement Therapy

scholarly journals Effect of Whole-course Nutrition Management on Patients with Esophageal Cancer Undergoing Concurrent Chemoradiotherapy: A Randomized Control Trial (P05-031-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Yanfang Qiu ◽  
Jie You ◽  
Quanjun Lv ◽  
Ling Yuan
Keyword(s):  
Quality Of Life ◽  
Esophageal Cancer ◽  
Nutritional Status ◽  
Concurrent Chemoradiotherapy ◽  
Nutrition Support ◽  
Control Group ◽  
Observation Group ◽  
Skin Reactions ◽  
Nutrition Management

Abstract Objectives Malnutrition is the most common complication of patients with esophageal cancer, and can lead to poor prognosis and death. It has been shown that good nutritional status can help improve patient outcomes and reduce complications. In the absence of specific evidence of the effect of nutrition on patients with esophageal cancer, the purpose of this study was to investigate the effect of total nutrition management on the prognosis and complications of patients with esophageal cancer through a randomized controlled trial. Methods 96 patients with esophageal cancer concurrent chemoradiation were randomized to observation group (treated by whole-nutrition management from the Nutrition Support Group (NST)) and control group (treated by the general nutritional method) for 6 weeks approximately. Dietary survey, Patient-Generated Subjective Global Assessment (PG-SGA), body measurement, blood index, quality of life survey and psychological condition survey were assessed at baseline and every week/at the end of the study. Complications, the completion rates of therapy, short-term efficacy evaluation as well as clinical outcomes were measured before discharge. Results A total of 85 subjects completed the study (observation group = 45, control group = 40). There were significantly different in the changes in serum albumin, prealbumin, and total protein between two groups throughout the trial (P < 0.05). Radioactive esophagitis, skin symptom of the complications, the roles, emotional functions, social functions, and general health status in the quality of life were statistically different before and after the intervention (P < 0.05). The difference in the change of other indicators was not statistically significant. Conclusions Whole-course nutrition management can improve the nutritional status of patients with concurrent chemoradiotherapy of esophageal cancer, reduce the severity of radiation esophagitis and radiation skin reactions, improve the quality of life and relieve their depressive symptoms. Funding Sources Wu Jieping Medical Foundation Special Fund for Clinical Research of 2017.

Randomized trial effect of an oral nutritional supplement with eicosapentaenoic acid on nutritional and inflammatory parameters, response and toxicity to chemotherapy, quality of life, and survival in treatment-naive patients with advanced non-small lung cancer.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e19594-e19594
Author(s):  
Karla Sanchez-Lara ◽  
Jenny Turcott ◽  
Eva Juarez ◽  
Martha de la Torre ◽  
Geraldine Villanueva ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Eicosapentaenoic Acid ◽  
Nutritional Supplement ◽  
Inflammatory Parameters ◽  
Oral Nutritional Supplement ◽  
Physical Scale ◽  
Nsclc Patients ◽  
Experimental Group

e19594 Background: Nutritional interventions have shown increased of energy intake but the effect of improvement in health related quality of life (HRQL) in non small cell lung cancer (NSCLC) patients is controversial. Eicosapentaenoic acid has been proposed to have anti-inflammatory, anticachectic and possibly could have antitumoral effects. Methods: Patients with advanced NSCLC naive to treatment were included and randomly assigned to receive diet and oral nutritional supplement enriched with EPA or only isocaloric diet. All patients received paclitaxel and cisplatin-carboplatin treatment. Weight, body composition measured with bioelectrical impedance analysis, dietary ingestion, inflammatory parameters and HRQL were assessed at baseline and after 1st and 2nd cycle. Response to chemotherapy and survival were evaluated. Results: Ninety-two patients were analyzed, (46 EPA, 46 control group). No basal differences between groups were found. Experimental group present significantly increased albumin levels, energy, proteins, lipids and carbohydrate intake, and reduced serum CPR, TNF-α and Neutrophyls/Lymphocytes index. Patients in experimental group presented minor prevalence of weight loss and increased 1.6 kg of lean body mass (LBM) compared with controls. In HRQL, experimental group presented an improvement in global and physical scale and anorexia, and regarding toxicity, fatigue and neuropathy diminished. There was no difference in response rate, progression free survival and overall survival between groups. Conclusions: EPA enriched supplementation provided a therapeutic advantage by increasing LBM and nutrients intake, improving HRQL, and reduce several toxicity parameters in NSCLC patients under chemotherapy. The study was registered with ClinicalTrials.gov, number NCT01048970.

Adapted ice cream as a nutritional supplement in cancer patients: impact on quality of life and nutritional status

2012 ◽  
Vol 14 (1) ◽  
pp. 66-72 ◽  
Author(s):  
Francesc Casas ◽  
Concha León ◽  
Esther Jovell ◽  
Joana Gómez ◽  
Angelo Corvitto ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Ice Cream ◽  
Nutritional Supplement

scholarly journals Integrative Treatment of Lung Cancer Patients: Observational Study of 57 Cases

2021 ◽  
Author(s):  
Lorenzo Anelli ◽  
Alessia Di Nardo ◽  
Massimo Bonucci
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Immune Status ◽  
Conventional Medicine ◽  
Integrative Therapy ◽  
Lung Cancer Patients ◽  
Retrospective Clinical Study

Abstract Introduction A retrospective clinical study was performed to identify the characteristics of patients with lung cancer treated with integrative cancer treatment in addition to conventional medicine. Materials and Methods We reviewed medical records for lung cancer patients who visited a single integrative setting in Rome, Italy. A total of 57 patients were included, and the majority had advanced-stage cancer. All of them underwent integrative therapy with nutrition and phytotherapy indications. The diet was designed to reduce most of possible factors promoting cancer proliferation, inflammation, and obesity. Foods with anti-inflammatory, prebiotic, antioxidant, and anticancer properties had been chosen. Herbal supplements with known effects on lung cancer were prescribed. In particular, astragal, apigenine, fucosterol, polydatin, epigallocatechin gallate, cannabis, curcumin, and inositol were used. Furthermore, medical mushrooms and other substances were used to improve the immune system and to reduce chemotherapy side effects. Five key parameters have been evaluated for 2 years starting at the first surgery: nutritional status, immune status, discontinuation of therapy, quality of life, and prognosis of the disease. Results A relevant improvement in parameters relative to nutritional status, immune status, and quality of life has been observed after integrative therapy compared with the same parameters at the first medical visit before starting such approach. Conclusion The results suggest that integrative therapy may have benefits in patients with lung cancer. Even though there are limitations, the study suggests that integrative therapy could improve nutritional status and quality of life, with possible positive effect on overall survival.

scholarly journals Women's Role in Food Production and Nutrition: Implications for Their Quality of Life

1988 ◽  
Vol 10 (3) ◽  
pp. 1-8 ◽  
Author(s):  
Gerd Holmboe-Ottesen ◽  
Ophelia Mascarenhas ◽  
Margareta Wandel
Keyword(s):  
Quality Of Life ◽  
Nutritional Status ◽  
Food Chain ◽  
Food Production ◽  
Women's Work ◽  
Energy Expenditures ◽  
Work Allocation ◽  
The Subject ◽  
Women's Role

The authors review the literature on the subject of how women's work along the food chain may affect their nutritional status and other aspects of their lives. They point out the discrimination against women in food and work allocation: women often work harder and have greater energy expenditures than men but get less food. Bennett makes this point in her article too, and McGuire touches on it as well.

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