scholarly journals Effect of Whole-course Nutrition Management on Patients with Esophageal Cancer Undergoing Concurrent Chemoradiotherapy: A Randomized Control Trial (P05-031-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Yanfang Qiu ◽  
Jie You ◽  
Quanjun Lv ◽  
Ling Yuan

Abstract Objectives Malnutrition is the most common complication of patients with esophageal cancer, and can lead to poor prognosis and death. It has been shown that good nutritional status can help improve patient outcomes and reduce complications. In the absence of specific evidence of the effect of nutrition on patients with esophageal cancer, the purpose of this study was to investigate the effect of total nutrition management on the prognosis and complications of patients with esophageal cancer through a randomized controlled trial. Methods 96 patients with esophageal cancer concurrent chemoradiation were randomized to observation group (treated by whole-nutrition management from the Nutrition Support Group (NST)) and control group (treated by the general nutritional method) for 6 weeks approximately. Dietary survey, Patient-Generated Subjective Global Assessment (PG-SGA), body measurement, blood index, quality of life survey and psychological condition survey were assessed at baseline and every week/at the end of the study. Complications, the completion rates of therapy, short-term efficacy evaluation as well as clinical outcomes were measured before discharge. Results A total of 85 subjects completed the study (observation group = 45, control group = 40). There were significantly different in the changes in serum albumin, prealbumin, and total protein between two groups throughout the trial (P < 0.05). Radioactive esophagitis, skin symptom of the complications, the roles, emotional functions, social functions, and general health status in the quality of life were statistically different before and after the intervention (P < 0.05). The difference in the change of other indicators was not statistically significant. Conclusions Whole-course nutrition management can improve the nutritional status of patients with concurrent chemoradiotherapy of esophageal cancer, reduce the severity of radiation esophagitis and radiation skin reactions, improve the quality of life and relieve their depressive symptoms. Funding Sources Wu Jieping Medical Foundation Special Fund for Clinical Research of 2017.

2021 ◽  
Vol 7 (5) ◽  
pp. 1570-1577
Author(s):  
Yan Pan ◽  
HaiPing Wu

Background Gastric cancer patients after surgery due to surgical trauma, digestive tract reconstruction of negative emotions and other factors, resulting in reduced postoperative food intake, nutritional status decreased immune function, resulting in tumor escape and postoperative recurrence or metastasis. Self-nutrition management combined with mindfulness intervention has a positive effect on postoperative nutritional status and quality of life of patients. Objective To analyze the effect of self-nutrition management combined with mindfulness intervention on postoperative nutritional status and quality of life of patients undergoing radical gastric cancer surgery. Methods A total of 130 gastric cancer patients admitted to our hospital from October 2018 to February 2021 were selected and divided into groups according to their intervention plan. All 130 patients were treated with laparoscopic radical resection of gastric cancer, 65 patients in the control group were given routine nutritional intervention and nursing intervention, and 65 patients in the observation group were given self-nutrition management intervention and mindfulness intervention. The postoperative rehabilitation indicators, hospitalization expenses and complications were compared between the two groups, and the changes in nutritional indicators between the two groups were detected. The Self-Rating Depression Scale (SDS) and the Self-Rating Anxiety Scale (SAS) were used to evaluate negative emotions. The European the Cancer Research and Treatment Organization Quality of Life Scale (QLQ-C30) evaluates the quality of life. Results The observation group’s first exhaust time, oral feeding time, and hospital stay were shorter than those in the control group. Compared with the control group, there was no significant difference in hospitalization expenses (P>0.05). Compared with before the intervention, the ALB, PA, and TRF of the two groups were increased (P<0.05), and the improvement of nutritional indicators in the observation group after the intervention was more obvious than that of the control group (P<0.05). Compared with before the intervention, the SDS scores and SAS scores of the two groups decreased (P<0.05), and the negative emotion scores of the observation group improved more significantly than those of the control group after the intervention (P<0.05). Compared with the pre-intervention, the two groups of QLQ-C30 scores in the areas of general health, physical function, role function, emotional function, social function and economic difficulties, etc. scores increased (P<0.05), fatigue, insomnia and loss of appetite, ect. The score decreased (P<0.05). There was no significant difference between the two groups in the areas of cognitive function, nausea and vomiting, constipation, diarrhea, etc. (P>0.05). In the area of pain and shortness of breath, observe the group was lower than before the intervention, but the difference between the control group and before the intervention was not statistically significant (P>0.05). The QLQ-C30 scores of the observation group after intervention (except in areas such as cognitive function, nausea and vomiting, constipation, diarrhea, financial difficulties, etc.) generally improved significantly compared with the control group (P<0.05). The incidence of complications in the observation group was lower than that in the control group, which was statistically significant (P<0.05). Conclusion Self-nutrition management combined with mindfulnesspromote postoperative recovery, reduce complications and negative emotions, improve nutritional status, and improve quality of life.


2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Chun Yi ◽  
Xiqiang Feng ◽  
Yueshuang Yuan

Objective. To explore the influence of PDCA cycle nursing based on network service on the quality of life and nutritional status of hypertension patients in home care. Methods. From January 2019 to December 2020, 116 hypertension patients in home care were selected as research objects. According to the random number method, the patients were divided into two groups: the control group (n = 58) and the observation group (n = 58). The control group was given routine home care service, while the observation group was given PDCA cycle nursing based on the network service. The effects of blood pressure control, quality of life, nutritional status, and emotional state of the two groups were analyzed. Results. The effective rate of blood pressure control in the observation group (93.10%) was higher than that in the control group (79.31%) ( P < 0.05 ). After intervention, the Generic Quality of Life Inventory-74 scores of the observation group were higher than those of the control group ( P < 0.05 ). After intervention, the malnutrition-inflammation score of the observation group was lower than that of the control group ( P < 0.05 ). After the intervention, the Self-Rating Anxiety Scale score and Self-Rating Depression Scale score of the observation group were lower than those of the control group ( P < 0.05 ). Conclusion. PDCA cycle nursing based on network service has a good blood pressure control effect on hypertension patients in home care, which can improve their quality of life and nutritional status and also relieve their bad emotions.


2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Jun Xue ◽  
Yanan Zhang ◽  
Zhaohe Song ◽  
Lei Wang ◽  
Baoyin Bo

Aims:Objective to explore the influence of family enteral nutrition support on nutritional status, lung function, activity tolerance and quality of life in elderly patients with chronic obstructive pulmonary disease (COPD) in stable stage and malnutrition. Methods: a total of 165 elderly patients with COPD and malnutrition discharged from the geriatric department of our hospital were randomly divided into two groups: control group (82 cases) and observation group (83 cases). The control group was treated with conventional diet, and the observation group was treated with conventional diet + enteral nutrition suspension (nengjin, 500kcal / bottle, newdisia Pharmaceutical Co., Ltd.) for support. One month later, they were observed The body mass index (BMI), serum albumin (ALB), total protein (TP), hemoglobin (HB), pulmonary function of the two groups were observed: forced vital capacity (FVC), forced expiratory volume (FEV1) in the first second, FEV1 / FVC, FEV1% of the predicted value (FEV1%), exercise tolerance and quality of life.Results (1) compared with the control group, BMI and ALB in the observation group increased significantly (t = 10.465, 6.189, P < 0.05), TP and Hb had no significant change, and the difference was not statistically significant (t = 1.310, 1.302, P > 0.05). (2) compared with the control group, FVC, FEV1, FEV1 / FVC, FEV1% in the observation group increased, with statistical differences (t = 11.999, 19.654, 13.418, 16.924, P < 0.05). (3) compared with the control group, the quality of life symptom score, activity score, influence score and total score of the observation group decreased significantly (t = 15.303, 6.773, 23.600, 14.766, P < 0.05), and 6MWT increased significantly (t = 111.962, P < 0.05).Conclusion enteral nutrition support can improve the nutritional status, lung function, activity tolerance and quality of life of elderly patients with COPD in stable stage and malnutrition.


1970 ◽  
Vol 1 (1) ◽  
Author(s):  
Jiajia Liu

Objective: To evaluate the clinical application of psychotherapy in the nursing center of patients with esophageal cancer. Methods: 100 patients with esophageal cancer treated in our hospital from January 2016 to January 2017 were randomly divided into observation group and control group. Fifty patients in each group were treated with routine rehabilitation. On treatment wise, observation group to take psychological treatment, compared between the two groups before and after treatment of anxiety, depression score, quality of life and CD3 + , CD4 + , CD8 + and other indicators. Results: The scores of depression and anxiety in the observation group were significantly lower than those in the control group (P < 0.05). The CD3 + , CD4 + and CD8 + were significantly higher in the two groups after treatment in compare with before treatment, the difference was statistically significant (P<0.05). Conclusion: Through psychological treatment, it can effectively improve the situation of patients with esophageal cancer, so that the quality of life of patients has been significantly improved, with high efficiency.


2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Lijun Chen ◽  
Wang Xu ◽  
Xiaoyong Ma ◽  
Genggeng Yu ◽  
Jianfeng Wang ◽  
...  

Objective: To explore the effect of respiratory rehabilitation training on the quality of life of pneumoconiosis patients. Methods: 76 pneumoconiosis patients who were treated in our hospital from April 2017 to December 2019 were selected as the research object, and randomly divided into 2 groups according to the order of admission by coin tossing, 38 cases in each group. The control group carried out health knowledge education on the basis of conventional treatment, and the observation group combined with respiratory rehabilitation training on the basis of the control group to compare the quality of life and lung function of the two groups of patients. Results: After 2 months of nursing care, scores of GQOLI-74 scale and pulmonary ventilation function indexes in the observation group were higher than those in the control group, with statistically significant differences (P<0.05). Conclusion: Respiratory rehabilitation training can improve pulmonary ventilation function of pneumoconiosis patients, improve the quality of life of patients, has good clinical application value.


2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Baoyi Huang ◽  
Fengmei Xu ◽  
Hongmei Kuang

Objective: To explore the effectiveness of pain nursing interventions for patients in ENT. Methods: The 200 ENT patients admitted from March 2018 to March 2020 were divided into observation group (n=100) and control group (n=100). The control group was used conventional clinical nursing methods, and the observation group received pain nursing intervention as a comparison with the control group. Results: The observation group had 83 cases, 14 cases and 3 cases of mild, moderate and severe pain, respectively, while the control group are of 43 cases, 43cases and 14 cases. Nursing intervention can significantly reduce the pain of patients after otolaryngology surgery, improve the quality of life of patients, and has high clinical value for application.


2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Xiange Zeng ◽  
Ling Li ◽  
Wenjing Wang ◽  
Lihui Zhu

Objective. To seek the improvement of rehabilitation nursing intervention on dysphagia and quality of life of patients with esophageal cancer undergoing radiotherapy. Methods. A total of 109 patients with esophageal cancer undergoing radiotherapy were selected as research objects. According to the random number table, they were separated into the control group (CG) and intervention group (IG), with 45 cases in CG and 64 cases in IG. In CG, patients were given routine nursing intervention, while those in IG were given rehabilitation nursing intervention. After intervention, the degree of acute radiation injury and the improvement of swallowing function were observed to compare the self-nursing ability, quality of life, and incidence of complications between the two groups. Results. The degree of injury in CG was heavier than that in IG. The improvement of swallowing function in IG was better than that in CG. The scores of self-nursing ability and life quality in IG were higher than those in CG, with statistically significant differences ( p < 0.05 ). The incidence of complications in IG was obviously lower than that in CG ( p < 0.05 ). Conclusion. Rehabilitation nursing intervention can ameliorate dysphagia, improve the quality of life, and reduce the incidence of complications for patients with esophageal cancer undergoing radiotherapy. It is worthy of clinical application.


2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Jing Li ◽  
Jinzhi Ji ◽  
Fuyan Liu ◽  
Lingling Wang

Objective: To investigate the clinical efficacy of insulin glargine combined with acarbose in the treatment of elderly patients with diabetes. Methods: One hundred and forty-four elderly patients with diabetes who received treatment between December 2016 and December 2017 in Binzhou People’s Hospital, China, were selected and divided into a control group and an observation group, 72 each, using random number table. The control group was treated with insulin glargine, while the observation group was treated with insulin glargine combined with acarbose. The therapeutic effect, improvement of quality of life and adverse reactions were compared between the two groups. Results: After treatment, fasting blood glucose (FBG), 2h postprandial blood glucose (PBG) and glycosylated hemoglobin (Hb Alc) of the two groups were lower than those before treatment, and the decrease degree of the observation group was significantly larger than that of the control group (P<0.05). The time needed for blood glucose reaching the standard level and daily insulin dosage of the observation group were significantly lower than that of the control group, and the differences were statistically significant (P<0.05). SF-36 scale score of the observation group was significantly better than the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: The combination of insulin Glargine and Acarbose can significantly control the blood glucose level of elderly patients with diabetes, improve the biochemical indicators, and enhance the quality of life. It is worth promotion in clinical practice. doi: https://doi.org/10.12669/pjms.35.3.86 How to cite this:Li J, Ji J, Liu F, Wang L. Insulin Glargine and Acarbose in the treatment of elderly patients with diabetes. Pak J Med Sci. 2019;35(3):---------. doi: https://doi.org/10.12669/pjms.35.3.86 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2021 ◽  
Vol 9 (4) ◽  
pp. 75
Author(s):  
Weijie Qi

<p>Objective: to analyze the effect of health education intervention in clinical nursing of patients with skin diseases. Methods: from January 2018 to March 2019, 122 patients with skin diseases were admitted to our hospital and randomly divided into two groups, with 61 cases in each group. The selected patients gave informed consent to this study. The control group was given routine dermatological care, and the observation group was given systematic health education. The treatment effect, mood score and quality of life score of the two groups were compared. Results: the treatment time, recurrence times and outpatient treatment times of the observation group were lower than those of the control group, the difference was statistically significant (P &lt; 0.05); the HAMA score and HAMD score of the observation group after intervention were lower than the control group, the difference was statistically significant (P &lt; 0.05). Conclusion: the implementation of health education for patients with skin diseases during the nursing process can effectively promote the recovery of the condition and reduce the number of treatments and recurrences. At the same time, it can improve the patients’ bad mental mood and improve the quality of life of the patients.</p>


2021 ◽  
Vol 7 (4) ◽  
pp. 392-399
Author(s):  
Jing Zhao ◽  
Lili Fu ◽  
Juan Zhu ◽  
Yan Liu ◽  
Xiaoqian Sun

To study and analyze the actual clinical effect of nursing intervention in stem cell therapy for stroke patients. A total of 9 stroke patients treated with stem cell therapy in our hospital from September 2018 to September 2019 were selected as the research and analysis objects. All patients were divided into observation group 5 stroke patients and control group 4 stroke patients by random number method. Both groups of patients were treated with stem cell therapy. Patients in the control group were treated with conventional nursing methods, and patients in the observation group were treated with nursing intervention methods. The treatment compliance, psychological status, quality of life and daily living ability before and after intervention were compared between the two groups. There were no significant differences in exercise training, disease monitoring and compliance with regular life between the two groups before intervention (P > 0.05), and the patients in observation group were significantly better than those in control group after intervention (P < 0.05), with significant differences. There was no significant difference in anxiety and depression scores between the two groups before intervention (P > 0.05), and after intervention, the patients in the observation group were significantly lower than those in the control group (P < 0.05), and the difference was statistically significant. There was no significant difference in quality of life and ability of daily living between the two groups before intervention (P > 0.05), and the patients in the observation group were significantly better than those in the control group after intervention (P < 0.05), the difference was statistically significant. The application of nursing intervention in stem cell therapy for stroke patients has a significant effect, which significantly improves the patient's compliance with the treatment, alleviates the negative emotions of patients, improves the psychological status of patients, improves the quality of life and daily living ability of patients, and is worthy of popularization and application in clinical nursing.


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