scholarly journals Chronic prosthetic joint infection caused by Listeria monocytogenes

2009 ◽  
Vol 58 (1) ◽  
pp. 138-141 ◽  
Author(s):  
Peter Kleemann ◽  
Eugen Domann ◽  
Trinad Chakraborty ◽  
Irene Bernstein ◽  
Michael Lohoff

We report what is to the best of our knowledge the first case of persistent human listeriosis. A housewife underwent excision of a leiomyosarcoma and implantation of a prosthetic knee device. Infection of the device with Listeria monocytogenes occurred and persisted for 2 years. Despite having an allergy to ampicillin, the patient was cured solely by antibiotics and without surgery.

2019 ◽  
pp. 1-3
Author(s):  
Nino Mirnik ◽  
Nino Mirnik ◽  
Rene Mihalič ◽  
Rihard Trebše

Background: Listeria monocytogenes causes bacteraemia in elderly and immunocompromised patients and rarely also in immunocompetent patients. In sporadic setting it can be challenging to diagnose. We present the first case of Listeria monocytogenes infection presenting as an acute infection of a prosthetic joint in an immunocompetent patient. Case summary: An immunocompetent patient presented with acute onset of right hip pain lasting for 3 days. The day before admission the patient had fever of 38.5°C and chills. The patient admitted having eaten raw meat some days prior to onset of symptoms. He had a prosthetic right hip implanted due to secondary arthritis 9 months prior to onset of hip symptoms. He was treated successfully with removal of mobile parts and appropriate antibiotic treatment. Conclusion: Sporadic focal infections with Listeria monocytogenes occur rarely and are often not diagnosed until the arrival of final culture results. Dietary history is also important when clinical history of patients is taken. Food consumption advice is important in immunocompromised, but also immunocompetent patients can get infected when eating raw food. Accurate diagnosis for orthopaedic samples is crucial. In order to successfully treat patients with a prosthetic joint infection, a tight collaboration between several specialists is needed.


2000 ◽  
Vol 11 (6) ◽  
pp. 329-331 ◽  
Author(s):  
Jihad Bishara ◽  
Eyal Robenshtok ◽  
Zmira Samra ◽  
Silvio Pitlik

Prosthetic joint infection is usually caused byStaphylococcus aureus, coagulase-negative staphylococci and, less commonly, by Gram-negative bacilli and anaerobes. A case of prosthetic joint infection due toPseudomonas stutzeriin a 73-year-old female with acute promyelocytic leukemia is presented, and the pertinent literature is reviewed. Although the patient had prolonged neutropenia, the infection was successfully treated with antibiotics and without artificial joint replacement.


2009 ◽  
Vol 58 (6) ◽  
pp. 829-831 ◽  
Author(s):  
Barbora Žaloudíková ◽  
Martin Kelbl ◽  
Libor Paša ◽  
Tomáš Freiberger

A rare case of a severe prosthetic joint infection in a 71-year-old immunocompetent woman is presented. Listeria monocytogenes was identified in two consecutive samples using broad-range PCR and sequencing, whereas cultivation remained negative for the first sample and streptococci of a non-group A streptococci, non-group B streptococci type were detected for the second one. This report demonstrates that the phenotypic approach may lead to misidentification of L. monocytogenes in a routine clinical setting. Molecular methods of pathogen detection might be useful when a rare and/or unexpected micro-organism is present or the sample is collected during antibiotic treatment.


2018 ◽  
Vol 3 (4) ◽  
pp. 230-233 ◽  
Author(s):  
Joanna Kedra ◽  
Valérie Zeller ◽  
Beate Heym ◽  
Philippe Lehours ◽  
Vanina Meyssonnier ◽  
...  

Abstract. We describe the case of an HIV-infected man who developed twice a Helicobacter cinaedi prosthetic joint infection. In our knowledge, it is the first case to date. Furthermore, it illustrates the fact that this bacterium is difficult to isolate and that recurrences can occur even after apparently successful treatment.


2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
A. Schimmenti ◽  
E. Brunetti ◽  
E. Seminari ◽  
B. Mariani ◽  
P. Cambieri ◽  
...  

Antimicrobial resistance in Gram-negative bacteria, particularly Enterobacteriaceae, has become a leading cause of morbidity and mortality and a serious public health concern. Gram-negative bacteria carrying extended-spectrum beta-lactamase (ESBL) enzymes now represent a significant proportion of all bacteria isolated from different countries worldwide. Furthermore, the increasing number of isolates carrying carbapenemases in recent years includes multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacteria. Here, we describe what, to our knowledge, is the first case of a patient with a prosthetic joint infection from carbapenemase-resistant Klebsiella pneumoniae (CRKP) successfully treated with ceftazidime-avibactam in Italy.


2020 ◽  
Vol 38 (10) ◽  
pp. 503-505
Author(s):  
Bartolomé Gómez-Arroyo ◽  
Patricia González-Donapetry ◽  
Alicia Rico-Nieto ◽  
Iker Falces-Romero

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Lisa F Barrett ◽  
Sailaja Devi Saragadam ◽  
Christina N DiMaria ◽  
Alejandro Delgado-Daza

ABSTRACT We present the first reported case of prosthetic joint infection caused by Clostridium bifermentans, which was treated with total joint washout and debridement allowing for the patient to retain his prosthesis and achieve full recovery. Clostridium bifermentans is a gram-positive, anaerobic, spore-forming bacterium. This organism was once considered to be non-pathogenic, but has recently been associated with cases of septic arthritis, empyema, osteomyelitis, soft tissue infection, brain abscess, bacteremia and endocarditis.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S234-S234
Author(s):  
Tasaduq Fazili ◽  
Ekta Bansal ◽  
Dorothy C Garner ◽  
Vijendra Bajwa

Abstract Background Nocardia are Gram-positive filamentous bacteria that cause Nocardiosis, a rare opportunistic infection. The most common site of infection is the lungs, with metastatic spread usually to the central nervous system. Prosthetic joint infection due to Nocardia is very rare. Methods We report the first case of prosthetic joint infection due to Nocardia veteran-elegans, and review the literature regarding Nocardia septic arthritis, with particular attention to prosthetic joint infection. Results The patient was a 35 year old male with history of Hodgkin’s Lymphoma for which he received chemotherapy previously, poorly controlled diabetes, motor vehicle accident in 2003 with right open tibial plateau fracture requiring hardware placement, who was admitted with a two week history of right knee pain and swelling. Knee aspiration revealed purulent fluid and synovial culture grew Nocardia species. He underwent right knee arthrotomy and debridement with removal of hardware. The Nocardia species was speciated as N. veterana-elegans, sensitive to trimethoprim/sulfamethoxazole, linezolid, clarithromycin, imipenem and amikacin. He was placed on oral linezolid for four weeks, which was then switched to oral trimethoprim/sulfamethoxazole, with a plan for a six month course of therapy. He has completed two months of therapy thus far and is doing well clinically. Nocardia is an uncommon cause of septic arthritis. We found only 37 cases reported in the English literature thus far. Amongst these, only six involved prosthetic joints, including our case, which is the first one to be caused by N. veterana-elegans.Three cases were caused by N. nova and one each by N. farcinica and asteroides. Septic arthritis due to Nocardia has a favorable outcome with a combination of surgical debridement and prolonged antimicrobial therapy of three to six months. For prosthetic joint infections, removal of hardware seems to carry a better prognosis. Trimethoprim/sulfamethoxazole is the preferred antimicrobial, including for bone and joint infection, although susceptibilities can vary amongst the different species. Conclusion Nocardia is an uncommon cause of septic arthritis. Prosthetic joint infection is very rare. Prognosis is fair with a combination of hardware removal and prolonged antibiotic therapy. Disclosures All Authors: No reported disclosures


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