scholarly journals Brain and lung metastasis of alveolar echinococcosis in a refugee from a hyperendemic area

2008 ◽  
Vol 57 (11) ◽  
pp. 1420-1423 ◽  
Author(s):  
Dennis Tappe ◽  
David Weise ◽  
Uwe Ziegler ◽  
Andreas Müller ◽  
Wolfgang Müllges ◽  
...  

Alveolar echinococcosis (AE) of the liver with cerebral and pulmonary metastasis was diagnosed in a Tibetan monk who initially presented with severe headache to an emergency department in Germany. Multiple lesions with perifocal oedema and severe compression of the third ventricle were seen with computed tomography (CT) of the brain. Glioma or cerebral metastasis of a hitherto undiagnosed abdominal or pulmonary malignancy was suspected. CT scans of the lung and liver demonstrated further tumorous masses. Magnetic resonance imaging of the brain revealed the cystic nature of the cerebral lesions and the patient had a highly positive serology for AE. The echinococcal aetiology of the brain lesions was confirmed by PCR for this refugee from an area where two disease entities, AE and cystic echinococcosis, are hyperendemic.

1995 ◽  
Vol 82 (3) ◽  
pp. 509-510 ◽  
Author(s):  
Ely Ashkenazi ◽  
Shlomo Pomeranz ◽  
Felix Umansky ◽  
John M. Gomori

✓ The authors present a simple and accurate new technique for preoperative localization of convexity lesions of the brain by means of magnetic resonance (MR) imaging. This method uses measurements from the initial diagnostic MR image and provides precise intraoperative guidance to cortical and subcortical cerebral lesions.


2017 ◽  
Vol 08 (01) ◽  
pp. 135-138 ◽  
Author(s):  
Prerna Garg ◽  
Muthusubramanian Rajasekaran ◽  
Salil Pandey ◽  
Gnanashanmugam Gurusamy ◽  
Devanand Balalakshmoji ◽  
...  

ABSTRACTNeuromyelitisoptica (NMO) and multiple sclerosis (MS) were once considered to be differing manifestation of same auto immune disease, NMO predominantly involving the optic nerve and cord. Now with discovery of NMO antibody the concept has changed and a spectrum of disorders with lesions in brain has been identified. Occasionally, brain may be the first or the only site of involvement in these disorders hence it is essential to be aware of this spectrum. The brain lesions in NMO/NMOSD may be located in characteristic regions and present with symptoms mimicking non neurological disease. We herein present a case of an adult female who was admitted with intractable vomiting and hiccups; subsequently on MRI brain found to have very tiny demyelinating foci in Area Postrema.


1998 ◽  
Vol 72 (1) ◽  
pp. 59-64 ◽  
Author(s):  
Y. Sato ◽  
M. Nakao ◽  
K. Nakaya ◽  
A. Ito

AbstractExperimental infection of larval Echinococcus multilocularis in the rodent brain was attempted to establish a murine model for cerebral alveolar echinococcosis. Balb/c mice and jirds were injected intracranially with 10% of a homogenated hydatid cyst mass. Small cystic larvae were observed macroscopically in the cranial cavity 1, 2 and 5 months post-infection in both mice and jirds. Some larval cysts from both rodents contained mature or immature protoscoleces. In mice, the laminated layer was found in the lateral ventricle 2 months post-infection but without protoscoleces. At five months post-infection, larger larval cysts were found in the cranial cavity of a mouse, which also demonstrated partial palsy of the legs. A laminated layer with mature protoscoleces was observed in the third ventricle and the mouse also harboured, in the left lung, a larval cyst containing protoscoleces surrounded by lymphocytes. Jirds were also found to be infected with metacestodes in the cranial cavity, but neither unusual behaviour nor establishment of cysts inside the brain was observed in jirds during the course of infection.


2018 ◽  
Vol 11 (2) ◽  
pp. 141-149
Author(s):  
Milan N. Mladenovski ◽  
Nikolay V. Vasilev ◽  
Mladen E. Ovcharov ◽  
Iliya V. Valkov

Summary Craniometric points are essential for orienting neurosurgeons in their practice. Understanding the correlations of these points help to manage any pathological lesion located on the cortical surface and subcortically. The brain sulci and gyri should be identified before craniotomy. It is difficult to identify these anatomical structures intraoperatively (after craniotomy) with precision. The main purpose of this study was to collect as much information as possible from the literature and our clinical practice in order to facilitate the placement of craniotomies without using modern neuronavigation systems. Operative reports from the last five years on cranial operations for cortical and subcortical lesions were reviewed. All the craniotomies had been planned, using four methods: detection of craniometric points, computed tomography (CT) scans/topograms, magnetic resonance imaging (MRI) scans/topograms, and intraoperative real-time ultrasonography (USG). Retrospectively, we analyzed 295 cranial operations. Our analysis showed that operating on for cortical lesions, we had frequently used the first and the second method mentioned above (118 patients), while in cases of subcortical lesions, we had used craniometric points, MRI scans/topograms and intraoperative real-time USG as methods of neuronavigation (177 patients). These results show that craniometric points are essential in both neurosurgical procedures.


EP Europace ◽  
2020 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
P Arvanitis ◽  
A K Johansson ◽  
M Frick ◽  
H Malmborg ◽  
E M Larsson ◽  
...  

Abstract Funding Acknowledgements Unrestricted grants from the Swedish Heart-Lung Foundation, the Swedish Research Council, Correvio International Sárl (CH) and Selanders stiftelse Background Patients with atrial fibrillation (AF) have a high incidence of cognitive impairment, which may be related to clinically silent microembolism causing cerebral infarctions. Purpose To explore the occurrence and timing of silent brain lesions following electrical cardioversion (CV) of recent onset AF in anticoagulant-naïve patients and to further study related effects on cognitive function and biomarkers of cerebral damage, S100b. Methods Patients with AF duration < 48 hours were prospectively included. Brain magnetic resonance imaging (MRI) and S100b, were obtained prior, after and 7-10 days following CV. Trail making tests (TMT-A and TMT-B) and their difference, ΔΤΜΤ, were assessed prior to CV, 7-10 days and 30 days after CV. Results Forty-three patients (84% males) with mean CHA2DS2-VASc score 0.6 ± 0.7 were included. Sequential MRI, including diffusion weighted scans, showed no new brain lesions after CV. Chronic white matter hyperintensities (WMH) were present at baseline in 21/43 (49%) patients. By partitioning the study population into four major groups according to the extend of WMH (Fazekas score 0 or ≥ 1) and the presence or absence of TE risk factors (CHA2DS2-VASc score 0 or ≥ 1), the TE risk as defined by CHA2DS2-VASc score ≥ 1, was associated with a higher incidence of WMH, Pearson χ2(1,N = 43)=3.95, p = 0.047. The S100b (µg/l) levels increased significantly from baseline, (mean ± SD) 0.0472 ± 0.0182 to 0.0551 ± 0.0185 after CV, p = 0.001 and then decreased 7-10 days after CV to 0.0450 ± 0.0186, p < 0.001. Subgroup analysis according to the presence of at least one TE risk factor as defined by CHA2DS2-VASc score showed that statistical significance of repeated measures ANOVA was maintained; for patients with no risk factors F (2,30)=12.59, p < 0.001 and for patients with CHA2DS2-VASc score ≥1 F(2,36)=4.43, p < 0.019. Consecutive TMT scores improved successively after CV, being statistically and clinically significant for TMT-B (p < 0.01) and ΔΤΜΤ (p = 0.005) between 7-10 days and 30 days after CV (Reliable Change Index >1.96). Conclusion New brain lesions could not be detected on MRI after CV, but the high incidence of white matter hyperintensities and the transient increase in S100b may indicate transient or minor brain damage undetectable by MRI thus heightening the need to reevaluate thromboembolic risk prior to CV even in low risk patients. Abstract Figure. S100b_TMT


1993 ◽  
Vol 51 (3) ◽  
pp. 329-332 ◽  
Author(s):  
Aílton Melo ◽  
Luciana Moura ◽  
Solana Rios ◽  
Marcos Machado ◽  
Gersonita Costa

Magnetic resonance imaging of the brain and spinal cord were carried out for seventeen consecutive patients with HTLV-1 associated myelopathy (HAM). Eight patients had brain abnormalities and four had decreased thoracic spinal cord diameter. Brain lesions were mostly located in subcortical and periventricular areas. Our data suggest that diffuse central nervous system lesions are present in patients with HAM.


2015 ◽  
Vol 6 (03) ◽  
pp. 392-394
Author(s):  
Rainy Betts ◽  
Curtis E. Margo ◽  
Mitchell Drucker

ABSTRACTA 65-year-old man developed bilateral vision loss 4 months after magnetic resonance imaging demonstrated no lesion in the vicinity of the optic chiasm, hypothalamus, and suprasellar tissues. Repeat computed tomography 3 months later showed a predominantly cystic mass of the suprasellar cistern with extension into the anterior third ventricle, which histologically was a craniopharyngioma. The clinical course of this case fuels the controversy whether craniopharyngiomas arise from embryonic rests or can be acquired. From a clinical perspective, it raises questions about when to obtain imaging studies dedicated to the chiasm and the appropriate interval in which a scan should be repeated to exclude structural causes of bilateral vision loss.


2006 ◽  
Vol 21 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Vincenzo Esposito ◽  
Sergio Paolini ◽  
Roberta Morace

✓The management of cavernous malformations of the brain is markedly influenced by the location of the lesions themselves. In the last decade, resection of cavernomas arising in the dominant insular lobe has been deemed safe only with the guidance of neuronavigation. Most navigation equipment, however, shares some minor drawbacks, including costs, longer operating time, and a variable loss of accuracy due to intraoperative brain shift. In this paper the authors present the case of a left dominant insular cavernoma that was successfully removed using a novel form of navigation that they call magnetic resonance imaging–based corticotopography. This technique, which is unaffected by the brain shift phenomenon, provided a simple and inexpensive alternative to standard neuronavigation. Selected cases of subcortical brain lesions could be conveniently approached using the same technique.


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