scholarly journals Brain activity reveals multiple motor-learning mechanisms in a real-world task

2020 ◽  
Author(s):  
Shlomi Haar ◽  
A. Aldo Faisal
Keyword(s):  
Motor Learning ◽  
Real World ◽  
Brain Activity ◽  
Skill Learning ◽  
Neural Dynamics ◽  
Complex Task ◽  
Motor Skill Learning ◽  
Learning Mechanisms ◽  
Learning Mechanism ◽  
Eeg Recordings

AbstractMany recent studies found signatures of motor learning in neural Beta oscillations (13– 30Hz), and specifically in the post-movement Beta rebound (PMBR). All these studies were in controlled laboratory-tasks in which the task designed to induce the studied learning mechanism. Interestingly, these studies reported opposing dynamics of the PMBR magnitude over learning for the error-based and reward-based tasks (increase versus decrease, respectively). Here we explored the PMBR dynamics during real-world motor-skill-learning in a billiards task using mobile-brain-imaging. Our EEG recordings highlight the opposing dynamics of PMBR magnitudes (increase versus decrease) between different subjects performing the same task. The groups of subjects, defined by their neural dynamics, also showed behavioural differences expected for different learning mechanisms. Our results suggest that when faced with the complexity of the real-world different subjects might use different learning mechanisms for the same complex task. We speculate that all subjects combine multi-modal mechanisms of learning, but different subjects have different predominant learning mechanisms.

scholarly journals Sensorimotor cortex beta oscillations reflect motor skill learning ability after stroke

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Svenja Espenhahn ◽  
Holly E Rossiter ◽  
Bernadette C M van Wijk ◽  
Nell Redman ◽  
Jane M Rondina ◽  
...  
Keyword(s):  
Motor Learning ◽  
Sensorimotor Cortex ◽  
Motor Skill ◽  
Motor Performance ◽  
Skill Learning ◽  
Motor Skill Learning ◽  
Healthy Controls ◽  
Stroke Patients ◽  
Beta Oscillations ◽  
And Performance

Abstract Recovery of skilled movement after stroke is assumed to depend on motor learning. However, the capacity for motor learning and factors that influence motor learning after stroke have received little attention. In this study, we first compared motor skill acquisition and retention between well-recovered stroke patients and age- and performance-matched healthy controls. We then tested whether beta oscillations (15–30 Hz) from sensorimotor cortices contribute to predicting training-related motor performance. Eighteen well-recovered chronic stroke survivors (mean age 64 ± 8 years, range: 50–74 years) and 20 age- and sex-matched healthy controls were trained on a continuous tracking task and subsequently retested after initial training (45–60 min and 24 h later). Scalp electroencephalography was recorded during the performance of a simple motor task before each training and retest session. Stroke patients demonstrated capacity for motor skill learning, but it was diminished compared to age- and performance-matched healthy controls. Furthermore, although the properties of beta oscillations prior to training were comparable between stroke patients and healthy controls, stroke patients did show less change in beta measures with motor learning. Lastly, although beta oscillations did not help to predict motor performance immediately after training, contralateral (ipsilesional) sensorimotor cortex post-movement beta rebound measured after training helped predict future motor performance, 24 h after training. This finding suggests that neurophysiological measures such as beta oscillations can help predict response to motor training in chronic stroke patients and may offer novel targets for therapeutic interventions.

scholarly journals Exercise and the Brain: Angiogenesis in the Adult Rat Cerebellum after Vigorous Physical Activity and Motor Skill Learning

1992 ◽  
Vol 12 (1) ◽  
pp. 110-119 ◽  
Author(s):  
Krystyna R. Isaacs ◽  
Brenda J. Anderson ◽  
Adriana A. Alcantara ◽  
James E. Black ◽  
William T. Greenough
Keyword(s):  
Motor Learning ◽  
Motor Skill ◽  
Volume Fraction ◽  
Vigorous Physical Activity ◽  
Molecular Layer ◽  
Learning Task ◽  
Skill Learning ◽  
Female Rats ◽  
Motor Skill Learning ◽  
Diffusion Distance

This study compared the morphology of cerebellar cortex in adult female rats exposed for 1 month to repetitive exercise, motor learning, or an inactive condition. In the exercise conditions, rats that were run on a treadmill or housed with access to a running wheel had a shorter diffusion distance from blood vessels in the molecular layer of the paramedian lobule when compared to rats housed individually or rats that participated in a motor skill learning task. Rats taught complex motor skills substantially increased the volume of the molecular layer per Purkinje neuron and increased blood vessel number sufficiently to maintain the diffusion distance. These results dissociate angiogenesis associated with increased neuropil volume (as seen in the motor learning group) from angiogenesis associated with increased metabolic demands (as seen in the exercise groups). While the volume fraction of mitochondria did not differ among groups, the mitochondrial volume fraction per Purkinje cell was significantly increased in the motor skill rats. This appears to parallel the previously reported increase in synapses and associated neuropil volume change.

Primary motor cortex disinhibition during motor skill learning

2014 ◽  
Vol 112 (1) ◽  
pp. 156-164 ◽  
Author(s):  
James P. Coxon ◽  
Nicola M. Peat ◽  
Winston D. Byblow
Keyword(s):  
Motor Cortex ◽  
Motor Learning ◽  
Skill Acquisition ◽  
Motor Skill ◽  
Primary Motor Cortex ◽  
Brain Plasticity ◽  
Intracortical Inhibition ◽  
Skill Learning ◽  
Motor Skill Learning ◽  
Pinch Grip

Motor learning requires practice over a period of time and depends on brain plasticity, yet even for relatively simple movements, there are multiple practice strategies that can be used for skill acquisition. We investigated the role of intracortical inhibition in the primary motor cortex (M1) during motor skill learning. Event-related transcranial magnetic stimulation (TMS) was used to assess corticomotor excitability and inhibition thought to involve synaptic and extrasynaptic γ-aminobutyric acid (GABA). Short intracortical inhibition (SICI) was assessed using 1- and 2.5-ms interstimulus intervals (ISIs). Participants learned a novel, sequential pinch-grip task on a computer in either a repetitive or interleaved practice structure. Both practice structures showed equivalent levels of motor performance at the end of acquisition and at retention 1 wk later. There was a novel task-related modulation of 1-ms SICI. Repetitive practice elicited a greater reduction of 1- and 2.5-ms SICI, i.e., disinhibition, between rest and task acquisition, compared with interleaved practice. These novel findings support the use of a repetitive practice structure for motor learning because the associated effects within M1 have relevance for motor rehabilitation.

What is consolidated during sleep-dependent motor skill learning?

2005 ◽  
Vol 28 (1) ◽  
pp. 70-71 ◽  
Author(s):  
Luca A. Finelli ◽  
Terrence J. Sejnowski
Keyword(s):  
Motor Learning ◽  
Memory Consolidation ◽  
Motor Skill ◽  
Computational Models ◽  
Learning Task ◽  
Skill Learning ◽  
Motor Skill Learning ◽  
Procedural Skills ◽  
Two Stages ◽  
Speed And Accuracy

Learning procedural skills involves improvement in speed and accuracy. Walker proposes two stages of memory consolidation: enhancement, which requires sleep, and stabilization, which does not require sleep. Speed improvement for a motor learning task but not accuracy occurs after sleep-dependent enhancement. We discuss this finding in the context of computational models and underlying sleep mechanisms.

scholarly journals Does Sleep Promote Motor Learning? Implications for Physical Rehabilitation

2009 ◽  
Vol 89 (4) ◽  
pp. 370-383 ◽  
Author(s):  
Catherine F Siengsukon ◽  
Lara A Boyd
Keyword(s):  
Older Adults ◽  
Young People ◽  
Motor Learning ◽  
Motor Skill ◽  
Physical Therapist ◽  
Skill Learning ◽  
Motor Skill Learning ◽  
Apparent Lack ◽  
Lack Of Sleep ◽  
Skill Enhancement

Sleep following motor skill practice has repeatedly been demonstrated to enhance motor skill learning off-line (continued overnight improvements in motor skill that are not associated with additional physical practice) for young people who are healthy. Mounting evidence suggests that older people who are healthy fail to demonstrate sleep-dependent off-line motor learning. However, little is known regarding the influence of sleep on motor skill enhancement following damage to the brain. Emerging evidence suggests that individuals with brain damage, particularly following stroke, do benefit from sleep to promote off-line motor skill learning. Because rehabilitation following stroke requires learning new, and re-learning old, motor skills, awareness that individuals with stroke benefit from a period of sleep following motor skill practice to enhance skill learning could affect physical therapist practice. The objective of this article is to present the evidence demonstrating sleep-dependent off-line motor learning in young people who are healthy and the variables that may influence this beneficial sleep-dependent skill enhancement. In young people who are healthy, these variables include the stages of memory formation, the type of memory, the type of instruction provided (implicit versus explicit learning), and the task utilized. The neural mechanisms thought to be associated with sleep-dependent off-line motor learning also are considered. Research examining whether older adults who are healthy show the same benefits of sleep as do younger adults is discussed. The data suggest that older adults who are healthy do not benefit from sleep to promote off-line skill enhancement. A possible explanation for the apparent lack of sleep-dependent off-line motor learning by older adults who are healthy is presented. Last, emerging evidence showing that individuals with chronic stroke demonstrate sleep-dependent off-line motor skill learning and some of the possible mechanisms for this effect are considered.

scholarly journals Exploring pain interference with motor skill learning in humans: a protocol for a systematic review

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e045841
Author(s):  
David Matthews ◽  
Edith Elgueta Cancino ◽  
Deborah Falla ◽  
Ali Khatibi
Keyword(s):  
Systematic Review ◽  
Motor Learning ◽  
Learning Strategies ◽  
Motor Skills ◽  
Motor Skill ◽  
Meta Analysis ◽  
Grey Literature ◽  
Skill Learning ◽  
Motor Skill Learning ◽  
The Impact

IntroductionMotor skill learning is intrinsic to living. Pain demands attention and may disrupt non-pain-related goals such as learning new motor skills. Although rehabilitation approaches have used motor skill learning for individuals in pain, there is uncertainty on the impact of pain on learning motor skills.Methods and analysisThe protocol of this systematic review has been designed and is reported in accordance with criteria set out by the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines. Web of Science, Scopus, MEDLINE, Embase and CINAHL databases; key journals; and grey literature will be searched up until March 2021, using subject-specific searches. Two independent assessors will oversee searching, screening and extracting of data and assessment of risk of bias. Both behavioural and activity-dependent plasticity outcome measures of motor learning will be synthesised and presented. The quality of evidence will be assessed using the Grading of Recommendations Assessment, Development and Evaluation approach.Ethics and disseminationNo patient data will be collected, and therefore, ethical approval was not required for this review. The results of this review will provide further understanding into the complex effects of pain and may guide clinicians in their use of motor learning strategies for the rehabilitation of individuals in pain. The results of this review will be published in a peer-reviewed journal and presented at scientific conferences.PROSPERO registration numberCRD42020213240.

scholarly journals Reward boosts reinforcement-based motor learning

2021 ◽  
Author(s):  
Pierre Vassiliadis ◽  
Gerard Derosiere ◽  
Cecile Dubuc ◽  
Aegryan Lete ◽  
Frederic Crevecoeur ◽  
...  
Keyword(s):  
Motor Learning ◽  
Beneficial Effect ◽  
Motor Skill ◽  
Healthy Subjects ◽  
Skill Learning ◽  
Motor Skill Learning ◽  
Rehabilitation Protocols ◽  
Motor Component ◽  
Task Success ◽  
Level Of Motivation

AbstractBesides relying heavily on sensory and reinforcement feedback, motor skill learning may also depend on the level of motivation experienced during training. Yet, how motivation by reward modulates motor learning remains unclear. In 90 healthy subjects, we investigated the net effect of motivation by reward on motor learning while controlling for the sensory and reinforcement feedback received by the participants. Reward improved motor skill learning beyond performance-based reinforcement feedback. Importantly, the beneficial effect of reward involved a specific potentiation of reinforcement-related adjustments in motor commands, which concerned primarily the most relevant motor component for task success and persisted on the following day in the absence of reward. We propose that the long-lasting effects of motivation on motor learning may entail a form of associative learning resulting from the repetitive pairing of the reinforcement feedback and reward during training, a mechanism that may be exploited in future rehabilitation protocols.

Aberrant brain activation following motor skill learning in schizophrenic patients as shown by functional magnetic resonance imaging

2001 ◽  
Vol 31 (6) ◽  
pp. 1079-1088 ◽  
Author(s):  
S. KODAMA ◽  
H. FUKUZAKO ◽  
T. FUKUZAKO ◽  
T. KIURA ◽  
S. NOZOE ◽  
...  
Keyword(s):  
Motor Skill ◽  
Brain Activity ◽  
Motor Task ◽  
Skill Learning ◽  
Motor Skill Learning ◽  
Bold Signal ◽  
Functional Magnetic Resonance ◽  
Complex Motor ◽  
Schizophrenic Patients ◽  
Signal Response

Background. Motor skill learning may be impaired in schizophrenia. While functional brain imaging studies have shown reduced activation during motor task performance in schizophrenic patients, brain activity changes with motor skill learning in these patients have not been studied by functional imaging.Methods. A sequential complex motor task involving the right hand was performed by nine medicated schizophrenic patients and 10 age-matched healthy controls. Functional magnetic resonance images were obtained using a gradient echo, echoplanar imaging (EPI) pulse sequence before and after 1 week of training in performing the task.Results. Bilaterally, patients showed significantly less blood oxygenation level-dependent (BOLD) signal response in the premotor area (PMA) before beginning motor training than controls. BOLD signal response increased in the left PMA of schizophrenic patients after 1 week of motor training; in contrast, the signal decreased in the left PMA of control subjects. Training effects concerning the number of finger movement sequences achieved did not differ between groups. Daily neuroleptic dose did not significantly affect changes with training in BOLD signal response in the PMA.Conclusions. These preliminary results suggest that schizophrenic patients have dysfunction of neural networks in areas including the PMA that are involved in executing a complex motor task. In terms of brain activity, motor learning may be less efficient or slower in the patients than in healthy subjects.

scholarly journals Neural Correlates of Motor Skill Learning Are Dependent on Both Age and Task Difficulty

2021 ◽  
Vol 13 ◽  
Author(s):  
Josje M. Bootsma ◽  
Simone R. Caljouw ◽  
Menno P. Veldman ◽  
Natasha M. Maurits ◽  
John C. Rothwell ◽  
...  
Keyword(s):  
Older Adults ◽  
Motor Learning ◽  
Neural Plasticity ◽  
Motor Skill ◽  
Task Difficulty ◽  
Brain Activity ◽  
Skill Learning ◽  
Age Related ◽  
Motor Practice ◽  
And Task

Although a general age-related decline in neural plasticity is evident, the effects of age on neural plasticity after motor practice are inconclusive. Inconsistencies in the literature may be related to between-study differences in task difficulty. Therefore, we aimed to determine the effects of age and task difficulty on motor learning and associated brain activity. We used task-related electroencephalography (EEG) power in the alpha (8–12 Hz) and beta (13–30 Hz) frequency bands to assess neural plasticity before, immediately after, and 24-h after practice of a mirror star tracing task at one of three difficulty levels in healthy younger (19–24 yr) and older (65–86 yr) adults. Results showed an age-related deterioration in motor performance that was more pronounced with increasing task difficulty and was accompanied by a more bilateral activity pattern for older vs. younger adults. Task difficulty affected motor skill retention and neural plasticity specifically in older adults. Older adults that practiced at the low or medium, but not the high, difficulty levels were able to maintain improvements in accuracy at retention and showed modulation of alpha TR-Power after practice. Together, these data indicate that both age and task difficulty affect motor learning, as well as the associated neural plasticity.

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