scholarly journals An integrative study of five biological clocks in somatic and mental health

2020 ◽  
Author(s):  
Rick Jansen ◽  
Josine Verhoeven ◽  
Laura KM Han ◽  
Karolina A Aberg ◽  
Edwin CGJ van den Oord ◽  
...  

ABSTRACTBiological clocks have been developed at different molecular levels and were found to be more advanced in the presence of somatic illnesses and mental disorders. However, it is unclear whether different biological clocks reflect similar aging processes and determinants. In ~3000 subjects, we examined whether 5 biological clocks (telomere length, epigenetic, transcriptomic, proteomic and metabolomic clocks) were interrelated and associated to somatic and mental health determinants. Correlations between biological clocks were small (all r<0.2), indicating little overlap. The most consistent associations with the advanced biological clocks were found for male sex, higher BMI, metabolic syndrome, smoking and depression. As compared to the individual clocks, a composite index of all five clocks showed most pronounced associations with health determinants. The large effect sizes of the composite index and the low correlation between biological clocks, indicate that one’s biological age is best reflected by combining aging measures from multiple cellular levels.

eLife ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Rick Jansen ◽  
Laura KM Han ◽  
Josine E Verhoeven ◽  
Karolina A Aberg ◽  
Edwin CGJ van den Oord ◽  
...  

Biological clocks have been developed at different molecular levels and were found to be more advanced in the presence of somatic illness and mental disorders. However, it is unclear whether different biological clocks reflect similar aging processes and determinants. In ~3000 subjects, we examined whether five biological clocks (telomere length, epigenetic, transcriptomic, proteomic, and metabolomic clocks) were interrelated and associated to somatic and mental health determinants. Correlations between biological aging indicators were small (all r < 0.2), indicating little overlap. The most consistent associations of advanced biological aging were found for male sex, higher body mass index (BMI), metabolic syndrome, smoking, and depression. As compared to the individual clocks, a composite index of all five clocks showed most pronounced associations with health determinants. The large effect sizes of the composite index and the low correlation between biological aging indicators suggest that one’s biological age is best reflected by combining aging measures from multiple cellular levels.


Author(s):  
Jutta Lindert

People who are forcibly displaced are forced to flee by serious threats to fundamental human rights, caused by factors such as persecution, armed conflict, and indiscriminate violence. Contemporary drivers of forced displacement are increasingly complex and interrelated. They include population growth, food insecurity, and water scarcity, at times compounded and multiplied by the effects of climate change. A refugee is someone who fled his or her home and country owing to “a well-founded fear of persecution because of his/her race, religion, nationality, membership in a particular social group, or political opinion,” according to the United Nations 1951 Refugee Convention. Internally displaced persons (IDPs) are people who have not crossed an international border but were forced to move to a different region than the one they call home within their own country. People who cannot return home without serious risk to their human rights have specific needs. Forced displacement, both within a country and to other countries, is a major life event that abruptly changes environmental living conditions, such as social networks, language, and cultural environment of the displaced populations. The changes in environmental living conditions and disruptions in life challenge both the individual and the families of the displaced persons. Both types of forced displacement challenge adaptational mechanisms of individuals and families. Accordingly, the challenges can contribute to changes in mental health and mental disorders. However, estimates of mental health, mental disorders, and mental health determinants vary across and between forcibly displaced persons. This heterogeneity in estimates is associated with differences between refugee groups and with methodological difficulties in assessing refugees’ mental health. Instruments to assess mental health need to be culture-grounded and gender-sensitive to capture the scope and extent of refugees’ mental health and mental disorders. Based on reliable and valid instrument needs for assessing mental health and mental disorders, determinants can be identified and intervention can be developed and evaluated.


2015 ◽  
Vol 2 (3) ◽  
Author(s):  
Dr. Gopal Chandra Mahakud ◽  
Ritika Yadav

The concept of mental health comprised to the health conditions of people without suffering any mental or psychological problem such as stress, depression, anxiety and other form of psychic disorders. In this regard it can be said that no one is free from and psychological, psycho-physical and psycho-social disorders from which we can derive that no one mentally healthy. But the concept of mental health defined free from the disorders those are prolonged and panic in nature. As the concept of mental health is subjective in nature, it varies from person to person. Besides free from the disorders, a person should pose some of the other positive characteristics to deal with the society effectively. Marry (1958) stated that, a person can be considered mentally healthy with the following characteristics such as (a) Positive attitudes toward himself/herself; (b) Realization of own potentialities through action; (c); Unification of in personality; (d) Degree of independence of social influences; (e) observations of the world around; and (f) Positive adapts to everyday life. Briefly, it can be said that positive mental health of the person make able to an individual to stand on his own two feet without making undue demands or impositions of others. In this regard the role of happiness in day to day life can make the individual more skilled to fight with different mental disorders. The present article is intended to find out the effects of happiness in day to day life in a social situation to deal with different mental disorders to make the individual mentally healthy and prosperous in life.


2018 ◽  
Vol 12 (4) ◽  
pp. 1054
Author(s):  
Vagner Marins Barcelos ◽  
Enéas Rangel Teixeira ◽  
Ana Beatriz de Nazareth Ribeiro ◽  
Lucas Duarte Braga da Silva ◽  
Diego Pereira Rodrigues ◽  
...  

RESUMOObjetivo: identificar os fatores positivos da musicoterapia em pacientes com transtornos mentais. Método: revisão integrativa, realizada de 2007-2017. As produções foram localizadas no mês de março de 2017, nas bases de dados Lilacs, BDEnf, Medline. Após sucessivas leituras dos artigos, foi selecionado 6 artigos, e os dados foram agrupados utilizando-se a técnica de análise de conteúdo. Resultados: foi observado que a musicoterapia pode ser utilizada como forma complementar de tratamento não farmacológico para auxiliar no restabelecimento do equilíbrio psíquico do indivíduo portador de transtornos mentais. Conclusão: com base no estudo apresentado, conclui-se que a musicoterapia como método terapêutico complementar atua de forma significativa na melhora do quadro clínico/psicológico do cliente, ao proporcionar melhora nas funções fisiológicas e cognitivas, sendo a restauração potencializada através do bem-estar, compartilhamento de suas emoções e a promoção da autonomia do paciente durante o cuidado. Descritores: Enfermagem; Enfermagem Psiquiátrica; Saúde; Saúde Mental; Musicoterapia; Pacientes.ABSTRACT Objective: to identify the positive factors of music therapy in patients with mental disorders. Method: integrative review, performed in 2007-2017. The productions were located in March 2017, on Lilacs, BDEnf and Medline databases. After successive readings of the articles, six articles were selected, and the data were grouped using a content analysis technique. Results: music therapy can be used as a complementary form of non-pharmacological treatment to assist in restoring mental equilibrium of the individual with mental disorders. Conclusion: Based on the presented study, music therapy, as a therapeutic complementary method, significantly improves the client’s clinical/psychological condition, when providing improvement in physiological and cognitive functions, maximizing the restoration through the well-being, sharing their emotions and promoting autonomy of the patient during the care. Descriptors: Nursing; Psychiatric Nursing; Health; Mental Health; Music Therapy; Patiens.RESUMEN Objetivo: identificar los factores positivos de la musicoterapia en pacientes con trastornos mentales. Método: revisión integrativa, realizada en 2007-2017. Las producciones fueron localizadas en el mes de marzo de 2017 en las bases de datos BDEnf, Lilacs, Medline. Después sucesivas lecturas de los artículos, se seleccionaron seis artículos y se agruparon los datos mediante la técnica de análisis de contenido. Resultados: se observó que la musicoterapia puede ser utilizada como una forma complementaria de tratamiento no farmacológico para ayudar a restablecer el equilibrio mental del individuo portador de trastornos mentales. Conclusión: según el estudio presentado, se concluye que la musicoterapia como método terapéutico complementar actúa en forma significativa en la mejora de la evolución clínica y/o psicológica del cliente, al proporcionar mejoras en las funciones cognitivas y fisiológicas, siendo la restauración maximizada a través del bienestar, compartimiento de sus emociones y la promoción de la autonomía del paciente durante el tratamiento. Descriptores: Enfermería; Enfermería Psiquiátrica; Salud; Salud Mental; Musicoterapia; Pacientes.


2017 ◽  
Vol 4 (1) ◽  
pp. 001-005
Author(s):  
Tutut Pujianto ◽  
Retno Ardanari Agustin

Mental health is an integral part of health, and a condition that affects the physical, mental, and  social  development  of  the  individual  optimally.  Mental  disorder  is  disturbances  in:  cognitive, volition, emotion (affective), and actions (psychomotor). Mental disorder is a collection of abnormal circumstances, whether physically related, or mentally. It is divided into two groups, namely: mental disorder  (neurosis)  and  mental  illness  (psychosis).  Mental  disorder  is  caused  by  some  of  the  above causes affected simultaneously or coincidence occurs. The purpose of this study was to increase the role of family and society in the treatment of mental disorder patients which was consequently could reduce the number of mental disorders patients This research used obsevational design with descriptive analy- sis. The subjects were family members who treat mental disorder patients as much as 16 respondents. The data collection was done in October 2012. The family role data grouped into appropriate and inappro- priate  category.  The  research  found  that  11  people  (68.75%)  in  the  category  of  inappropriate,  and appropriate by 5 people (31.25%), with average family role of 63.19%. The higher of inappropriate category was because 9 respondents (56.25%) in the age of elderly (> 50 years). This condition caused a decrease in the ability to perform daily activities, including health treatment. There were 4 patients who have been treated for 7-14 years, so the family feels accustomed to the condition of the patient. There were 8 people (50%) in productive age treated the patients, so it could not be done continuously. Based on these conditions, there should be efforts to increase knowledge and willingness of the patients and families, in caring for patients with mental disorders. The examples of such activities were to consult with the nearest health employees, and report to the health worker if there is a risky condition immedi- ately.


2018 ◽  
Vol 28 (4) ◽  
pp. 528-541 ◽  
Author(s):  
Silke Schwarz

Historically, psychiatry and clinical psychology focused on understanding how stressful life conditions led to psychiatric disorders. With the rise of positive psychology, the focus shifted to thriving through adversity and to concepts such as resilience. However, the number of mental disorders is still increasing. Due to a neoliberal Western decontextualizing stance in psychology, the concept of resilience is at risk of reproducing power imbalances and discrimination within our society. Resilience is analysed from a critical perspective, mostly with a Marxist point of view, including Foucauldian discursive approaches, as well as a biomedical critique of the current mental health system, to illustrate the shortcomings of Western psychologies. This article illustrates how a contextualized understanding of resilience that accounts for political, historical, and socioeconomic contexts at analytical levels besides the individual may overcome this ethnocentric and neoliberal bias.


Author(s):  
Kilda Çela Gusha ◽  
Irena Shala ◽  
Remila Kalo

Mental health problems are conditions that do not meet the criteria for disease but affect the normal quality and continuity of everyday life. They are the emotional and psychological difficulties of the individual, which occur as a result of circumstantial or persistent stresses or of a reflection of the emotions between the individual and the environment where he lives (WHO, 2005). Health is seen as "not just a lack of sickness or disability," but rather as "a complete physical, mental and social well-being." This definition significantly expands the concept of mental health, which should not be defined in a restrictive manner as the absence of mental disorders, but should be defined in a positive and comprehensive view (WHO, 1985). Ultimately, mental health is defined as "a state of well-being in which the individual realizes his or her own potential, is able to cope with daily life concerns, is productive and fruitfully in his work, and is capable of delivering his contribution to the community where he lives (WHO, 2001). Mental health problems are usually associated with important concerns in social, professional, or other important activities. In many cases, there appears to be a continuity between mental health problems and mental disorders, making the diagnosis even more complex (CDC, 2011). Policies and Legislative Frameworks. Law on MS – 1996. Implementation of LLL remains low as a consequence of inadequate infrastructure (health, social and legal). There is no national or local body to monitor human or patient rights in the institutions of the MS.Policy on the Development of Mental Health Services in Albania - March 2003. Action Plan for the Development of Mental Health Services in Albania - May 2005. Mental and emotional problems are a concern for many elderly people. Depression often occurs as a result of the death of a spouse or close friends. Even this kind of loss and even more important and more common is the loss of respect of others. With retirement an individual does not feel more useful to his family, to society, and even more to himself.


2021 ◽  
Vol p5 (5) ◽  
pp. 2993-2997
Author(s):  
Gupta Mohini ◽  
Bansal Harendra ◽  
Sharma Shraddha ◽  
Sharma Vivek

WHO has proposed that mental health is - ' A state of well-being in which the individual realizes his or her abili- ties can cope with the normal stresses of life, can work productively and fruitfully and can make a contribution to his or her community.’ Mental disability has become one of the most dreadful conditions across the world. It is prevalent in almost every society and creates an enormous social and economic burden. Mental illness is charac- terized by disturbance in person, emotion, thoughts, or behaviour. The term mental illness (Mental behaviour) includes a wide variety of disorders, ranging from mild distress to severe impairment of social and occupational functioning. In 2017, 197.3 million people had mental disorders in India, including 45.7 million with depressive disorder and 44.9 million with anxiety disorder. A significant, but modest, correlation between the prevalence of depressive disorder and the suicide death rate at the state level for females and males. Medhya Rasayana affects the human psyche and mainly work at the level of neurotransmitters. Daily use of Medhya Rasayana is not only good for memory but also promotion of mental health. So, these media rasayan (Yashtimadhu, Guduchi, Shankhpushpi, Mandukaparni) drugs are effective in the treatment of mental disorders. Keywords: Medhya, Rasayan, Anxiety, Neurotransmitters.


Author(s):  
Susan Bailey

Juvenile crime and delinquency represent a significant social and public health concern. Both rates of mental disorders and offending are high during adolescence. This chapter reviews prevalence rates of mental disorders in young offenders, screening, and assessment of juveniles, principles of interventions with young offenders before describing principles of forensic mental health, policy and practice, how mental disorders in adolescence can impact on offending and antisocial behaviour, how policy is shaping practice in this field and how mental health practitioners may be involved in meeting mental health needs and undertaking medico-legal assessments Delinquency, conduct problems, and aggression all refer to antisocial behaviours that reflect a failure of the individual to conform his or her behaviour to the expectations of some authority figure, to societalnorms, or to respect the rights of other people. The ‘behaviours’ can range from mild conflicts with authority figures, to major violation of societalnorms, to serious violations of the rights of others. The term ‘delinquency’ implies that the acts could result in conviction, although most do not do so. The term ‘juvenile’ usually applies to the age range, extending from a lower age set by age of criminal responsibility to an upper age when a young person can be dealt with in courts for adult crimes. These ages vary between, and indeed within, countries and are not the same for all offences.


Author(s):  
Asrenee AB. Razak

There is an increasing trend of mental health issues in Malaysia. 1 in 3 Malaysian aged over 16 years old is at risk of having a mental health problem, and the trend is on the rise. The burden of mental health disorders on health and productivity, however, has long been underestimated. It is partly due to the cultural stigma attached to mental disorders. The recent 2018 Malaysia's Healthiest Workplace survey reported that more than half of employees in the survey have been affected by job-related stress such as burnout, anxiety, depression, and could lead to suicide. The serious consequences of these mental health issues not only affecting the individual but also lead to negative impacts on the productivity and performance of the company. On the other hand, workplaces that promote good mental health, and support people with mental disorders are more likely to reduce absenteeism, increase productivity as well as could benefit from associated economic gains. It is crucial for the workplace to integrate mental health intervention in their health and wellbeing strategy.  Among the useful intervention is mindfulness training. Mindfulness is not only proven to reduce the work stress but also teaches the employees to appreciate life and positively cope with their job demands. This presentation outlines the benefits of mindfulness and how it can be applied in daily life.


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