scholarly journals The prevalence of antibodies to SARS-CoV-2 among blood donors in China

2020 ◽  
Author(s):  
Le Chang ◽  
Wanghen Hou ◽  
Lei Zhao ◽  
Yali Zhang ◽  
Yanbin Wang ◽  
...  
Keyword(s):  
Blood Donors ◽  
Blood Donation ◽  
Cross Sectional Study ◽  
Blood Type ◽  
Igg Antibody ◽  
Cross Sectional ◽  
Viral Spread ◽  
Independent Risk Factors ◽  
Effective Public Health ◽  
Central South

Objectives The prevalence of antibodies to SARS-CoV-2 among blood donors in China remains unknown. To reveal the missing information, we investigated the seroprevalence of SARS-CoV-2 antibodies among blood donors in the cities of Wuhan, Shenzhen, and Shijiazhuang of China. Design Cross-sectional study Setting Three blood centers, located in the central, south and north China, respectively, recruiting from January to April 2020. Participants 38,144 healthy blood donors donated in Wuhan, Shenzhen and Shijiazhuang were enrolled, who were all met the criteria for blood donation during the COVID-19 pandemic in China. Main outcome measures Specific antibodies against SARS-CoV-2 including total antibody (TAb), IgG antibody against receptor-binding domain of spike protein (IgG-RBD) and nucleoprotein (IgG-N), and IgM. Pseudotype lentivirus-based neutralization test was performed on all TAb-positive samples. In addition, anonymous personal demographic information, including gender, age, ethnicity, occupation and educational level, and blood type were collected. Results A total of 519 samples from 410 donors were confirmed by neutralization tests. The SARS-CoV-2 seroprevalence among blood donors was 2.29% (407/17,794, 95%CI: 2.08% to 2.52%) in Wuhan, 0.029% (2/6,810, 95%CI: 0.0081% to 0.11%) in Shenzhen, and 0.0074% (1/13,540, 95%CI: 0.0013% to 0.042%) in Shijiazhuang, respectively. The earliest emergence of SARS-CoV-2 seropositivity in blood donors was identified on January 20, 2020 in Wuhan. The weekly prevalence of SARS-CoV-2 antibodies in Wuhan's blood donors changed dynamically and were 0.08% (95%CI: 0.02% to 0.28%) during January 15 to 22 (before city lockdown), 3.08% (95%CI: 2.67% to 3.55%) during January 23 to April 7 (city quarantine period) and 2.33% (95%CI: 2.06% to 2.63%) during April 8 to 30 (after lockdown easing). Female and older-age were identified to be independent risk factors for SARS-CoV-2 seropositivity among donors in Wuhan. Conclusions The prevalence of antibodies to SARS-CoV-2 among blood donors in China was low, even in Wuhan city. According to our data, the earliest emergence of SARS-CoV-2 in Wuhan's donors should not earlier than January, 2020. As most of the population of China remained uninfected during the early wave of COVID-19 pandemic, effective public health measures are still certainly required to block viral spread before a vaccine is widely available.

scholarly journals The prevalence of antibodies to SARS-CoV-2 among blood donors in China

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Le Chang ◽  
Wangheng Hou ◽  
Lei Zhao ◽  
Yali Zhang ◽  
Yanbin Wang ◽  
...  
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Blood Donors ◽  
Antibody Testing ◽  
Old Adults ◽  
Viral Spread ◽  
Health Measures ◽  
Independent Risk Factors ◽  
Effective Public Health ◽  
Age And Sex

AbstractIn this study, we investigate the seroprevalence of SARS-CoV-2 antibodies among blood donors in the cities of Wuhan, Shenzhen, and Shijiazhuang in China. From January to April 2020, 38,144 healthy blood donors in the three cities were tested for total antibody against SARS-CoV-2 followed by pseudotype SARS-CoV-2 neutralization tests, IgG, and IgM antibody testing. Finally, a total of 398 donors were confirmed positive. The age- and sex-standardized SARS-CoV-2 seroprevalence among 18–60 year-old adults (18–65 year-old in Shenzhen) was 2.66% (95% CI: 2.24%–3.07%) in Wuhan, 0.033% (95% CI: 0.0029%–0.267%) in Shenzhen, and 0.0028% (95% CI: 0.0001%–0.158%) in Shijiazhuang, respectively. Female sex and older-age were identified to be independent risk factors for SARS-CoV-2 seropositivity among blood donors in Wuhan. As most of the population of China remained uninfected during the early wave of the COVID-19 pandemic, effective public health measures are still certainly required to block viral spread before a vaccine is widely available.

scholarly journals HEPATITIS B AND HEPATITIS C;

2018 ◽  
Vol 25 (08) ◽  
pp. 1245-1251
Author(s):  
Mustansar Billah ◽  
Syed Muhammad Raza Shah ◽  
Muhammad Mujtaba Hashir
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Blood Bank ◽  
Research Centre ◽  
Cross Sectional ◽  
Medicine Department ◽  
And Gender

Objectives: To determine the frequency of HBV and HCV among blood donorscoming voluntarily at the blood bank of Ibne- Siena hospital and research centre, Multan,Pakistan, to ascertain the disease burden in the community for their future prevention andcontrol. Study Design: It was a descriptive, cross- sectional study on blood units donated byhealthy individuals coming voluntarily for blood donation, and willing to get their blood testedfor HBV, HCV. Setting: Community medicine department of Multan medical and dental collegeMultan, and blood bank of affiliated tertiary hospital, Ibn-e- Siena hospital Multan. Period: Sixmonths period from Jan 2016 to June 2016. Materials and Methods: Data of the blood donorswas collected. Present study was based on previous well maintained records of hospital bloodbank. During the reported period, a total of 1195 blood donors attended the blood bank, andthey all were screened for HBsAg and anti-HCV. SPSS- 16 was used to analyze the data, fordetermination of frequencies of Hepatitis- B, and C according to the age and gender. Results:Total numbers of blood donors were 1195. 1191 were males, and 4 were females. All thefemales were negative for both HBV, and HCV. Males positive for HBV were 18 (1.5 %), andthose Positive for HCV were 27 (3.2%).

A Cross-Sectional Study of Sociodemographic Profile of Blood Donors and Their Knowledge about Blood Donation in a Rural Area of Kerala

2021 ◽  
Vol 8 (29) ◽  
pp. 2615-2619
Author(s):  
Indu Pachampully Kumaran ◽  
Archana K.A ◽  
Meena Dharmadas ◽  
Sasikala Nadanganan ◽  
Anu Kumar B ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Blood Donor ◽  
Blood Donors ◽  
Blood Donation ◽  
Cross Sectional Study ◽  
Director General ◽  
Sectional Study ◽  
Donor Motivation ◽  
Cross Sectional ◽  
Communication Modalities

BACKGROUND Even in the presence of sufficient voluntary blood donors, the need of blood is not met yet. We wanted to evaluate the causes that hinder the smooth functioning of well-maintained blood transfusion services (BTS). METHODS This is a population based cross-sectional study conducted among blood donors from voluntary outreach blood donation camp for period of one year. Total 1536 blood donors from 32 blood donation camps were subjected to study for the sociodemographic characteristic and their knowledge of blood donation. Statistical analysis of data was done using Microsoft Excel, analysed using statistical package for social sciences (SPSS) ver.16 software. RESULTS A total of 32 blood donation camps were conducted during the study period that provided 1536 donors. In most of the camps, male donors (75 %) were more than female donors. Donors of age group of 30 to 39 years (43.9 %) were more when compared to others. Donors those who were married accounted for 79.9 %. Blood donors of Hindu religion (53 %) were more. CONCLUSIONS The main hindrance for blood donor motivation is lack of knowledge. Literacy and chance to mingle in society have a positive effect on blood donor motivation. Targeting of effective donor motivation, recruitment, and retention were attained by conducting awareness classes, seminars, workshops, and visual communication modalities. KEYWORDS World Health Organization, Altruistic Blood Donor, Blood Transfusion Services, Transfusion Transmitted Infections, Blood Components and Plasma Derivatives, Director General of Health Services (DGHS), National Blood Transportation Council (NBTC)

scholarly journals Epidemiological Profiles of Foreign-Born and US-Born Hispanic Blood Donors in a Major Metropolitan Area in the United States

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Adelbert B. James ◽  
Cassandra D. Josephson ◽  
Marta I. Castillejo ◽  
George B. Schreiber ◽  
John D. Roback
Keyword(s):  
Blood Donors ◽  
Blood Donation ◽  
The United States ◽  
Cross Sectional Study ◽  
Foreign Born ◽  
Rates Of Return ◽  
Cross Sectional ◽  
Major Metropolitan Area ◽  
The Us ◽  
Donated Blood

Background. The explosive growth of Hispanics in the US makes this population a significant and untapped source for blood donation. Methods. A cross-sectional study was performed to evaluate blood donation behaviors and demographics of foreign-born and US-born Hispanic donors between 2006 and 2009 in metropolitan Atlanta, GA, USA. Bivariate analyses and multivariate logistic regression were used to assess factors associated with foreign-born donors. Results. 5,119 foreign-born and 11,841 US-born Hispanics donated blood. Foreign-born Hispanic donors were more likely than US-born donors to be blood group O (57.6% versus 52.0%; P<.001) and more frequent donors (2.2 versus 2.0; P<.001). Cuban-born donors had the highest rates of return donation (63.2%). In contrast, Mexicans, the most prevalent subpopulation among foreign-born Hispanic donors (31.8%), had the lowest rates of return donation (42.0%). Conclusions. The heterogeneity found among Hispanic donors in this study is valuable for the design of recruitment strategies to increase blood donations.

scholarly journals Seroprevalence and Trends of HTLV-1/2 among Blood Donors of Santo Domingo, Dominican Republic, 2012-2017

2020 ◽  
Author(s):  
Emiliana Eusebio-Ponce ◽  
Francisco Javier Candel ◽  
Robert Paulino-Ramirez ◽  
Irene Serrano-García ◽  
Eduardo Anguita ◽  
...  
Keyword(s):  
Dominican Republic ◽  
Blood Donors ◽  
Blood Donation ◽  
Cross Sectional Study ◽  
Published Data ◽  
Santo Domingo ◽  
Cross Sectional ◽  
Blood Donations ◽  
Period Prevalence ◽  
Donation Activity

Objectives. Being a Caribbean country, the Dominican Republic is considered endemic for HTLV-1. Viral screening in blood banks is recommended for this blood borne infection. The purpose of this work is to analyze the seroprevalence and trends of HTLV-1/2 in the Dominican Republic blood donors; it is focused on Santo Domingo, the capital of the country, which has the largest blood donation activity. We also aim at comparing our findings with published data from neighboring countries. Patients and methods. We performed a retrospective cross-sectional study of 10 blood centers of Santo Domingo, which reported HTLV and the other blood-transmitted infections in full. They represent more than 40% of the province’s blood donations. Annual seroprevalence of HTLV-1/2, period prevalence (2012-2017), and time trend were determined. Results. A total of 352,960 blood donations were evaluated. The HTLV-1/2 period prevalence was 0.26% (929/352,960)(95% CI: 0.24–0.28%). We also found a marked predominance of replacement donation (90.4%) in comparison to voluntary contributions (9.6%). Therefore, this blood donor study may provide clues on the general prevalence of the infection. Conclusions. Seroprevalence of HTLV-1/2 in blood donors of Santo Domingo, Dominican Republic, showed a relatively low and steady trend in the studied period.

scholarly journals Seroprevalence of Cytomegalovirus among Blood Donor in Transfusion Medicine: Study from Bangladesh

2020 ◽  
Vol 5 (01) ◽  
Author(s):  
Dr. Sheikh Saiful Islam Shaheen ◽  
Dr. Md. Ashraful Hoque ◽  
Dr. Jannatul Ferdous
Keyword(s):  
Blood Donors ◽  
Blood Donation ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Preterm Neonates ◽  
Transfusion Medicine ◽  
Cmv Infection ◽  
Cross Sectional ◽  
Medical University ◽  
Cmv Disease

Background: Cytomegalovirus (CMV) infection is a matter for concern among blood bank professionals and blood transfusion recipient, especially in cases of transfusion to neonates and immunocompromised patients. Objective: The aim of the study was to investigate the seroprevalence of cytomegalovirus with the purpose of determining routine CMV screening for donors. Method: A descriptive cross sectional study was carried out in the Department of Transfusion Medicine in Bangabandhu Sheikh Mujib Medical University from January 2017 to December 2017. A total of 150 blood donors were selected by convenient sampling technique. Result: The seroprevalence of cytomegalovirus is 91% for IgG and 4% for IgM. Association was found in between IgG and age,sex.In case of age anti-CMV-IgG,c2= 26.5, t = 9.49; c2> t (Association Exists),for sex anti-CMV-IgG: df = 1, CI = 95%, c2= 17.8, t = 3.84; c2> t (Association Exists)Anti-CMV-IgM: df = 1, CI = 95%, c2= 10.7, t = 3.84; c2> t (Association Exist). This study was undertaken to find out seroprevalence of Cytomegalovirus among blood donors in the department of transfusion medicine. The incidence of cytomegalovirus is 91.3% for IgG and 4% for IgM. Most of the IgG positive subjects were in 38-47 years and for IgM were in 28-37 years. It was observed that seroprevalence of CMV was more in female (94.9% in case of IgG& 6.8% in IgM). It was observed that the highest prevalence of IgG was 3out of 3 (100%)in illiterate and that of IgM was 1 out of 3(33.33%) in illiterate level of education. In conclusion it was found that seroprevalence of cytomegalovirus was 91.3% for IgG and 4% for IgM. Association was found in between IgG & age, sex. Conclusion: Prospective blood donors should be screened for CMV most especially for immunocompromised recipients. Leucoreduced blood products from CMV seronegative donors should be given to preterm neonates, infants as this will prevent transfusion associated perinatal CMV disease. There should be more campaign and awareness on provision of voluntary blood donation for CMV negative blood. Program should be made to create awareness in the community on the significant impact of CMV infection on health.

scholarly journals Satisfaction and intention to return for donation among non-remunerated blood donors in a tertiary hospital in Malaysia

2021 ◽  
Author(s):  
Pei Pei Tan ◽  
Chee Tao Chang ◽  
Jernih Abdul Rahman ◽  
Sabariah Mohd Noor
Keyword(s):  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Tertiary Referral Hospital ◽  
Cross Sectional ◽  
High Satisfaction ◽  
Donation Process ◽  
Intention To Return ◽  
Self Administered Questionnaire

Abstract BackgroundIn Malaysia, blood supply relies mainly on non-remunerated blood donors. This study aimed to assess the satisfaction and experience of blood donors during the blood donation process and their intention to return for donation in future.Materials and MethodsThis was a cross-sectional study conducting using a self-administered questionnaire among blood donors. Study was conducted in a tertiary referral hospital and two mobile sites in the Perak state of Malaysia. The questionnaire was initially developed in the Malay language with 5-point Likert scale. The questionnaire comprised of three domains: i) sociodemographic characteristics ii) donor’s satisfaction towards staff iii) donors’ experience and satisfaction towards the donation process. ResultOf the 400 questionnaires distributed, 369 (92.3%) were analysed. The mean age of the donors was 35.98±10.67 years. Most of the donors were male (75.1%), of Malay ethnicity (60.2%) and regular donors (65.6%). Majority of the blood donors reported high satisfaction towards the interviewer (99.0%), blood taking skill of the staff (97.5%), politeness and friendliness of the staff (99.5%) and communication with the staff (98.9%). Minority of the blood donors expressed dissatisfaction towards the parking spaces (13.4%), refreshment (0.8%), and the blood donation operation hours (0.8%). Generally, the respondents had high overall satisfaction level (99.2%) and high intention to donate blood again in the future (98.9%). Conclusion Blood donors in the current study were highly satisfied towards the staff and blood donation process. Translation of high intention to return for donation to actual donation behaviour require further exploration in future studies.

scholarly journals PROPORTION OF RHESUS BLOOD TYPE PHENOTYPES OF ROUTINE BLOOD DONORS AT BLOOD DONOR UNIT INDONESIAN RED CROSS IN BANDUNG CITY

2019 ◽  
Vol 25 (2) ◽  
pp. 155
Author(s):  
Ivana Dewi ◽  
Nadjwa Zamalek Dalimoenthe ◽  
Anna Tjandrawati ◽  
Nida Suraya
Keyword(s):  
Blood Donor ◽  
Blood Donors ◽  
Blood Donation ◽  
Ethylenediaminetetraacetic Acid ◽  
Blood Type ◽  
Red Cross ◽  
Cross Sectional ◽  
Matching Problems ◽  
Routine Blood ◽  
Hemolytic Transfusion Reaction

Blood type phenotype incompatibility including Rhesus between donors and patients may result in cross-matching problems, triggering alloimmunization, and caused Hemolytic Transfusion Reaction (HTR). Rhesus blood type incompatibility between mother and fetus may cause Hemolytic Disease of Fetus and Newborn (HDFN). Pretransfusion phenotypic blood groups matching also reduce cost efficiently which means antibody screening is no longer needed. The purpose of the study is to find the proportion Rhesus blood type phenotypes in routine blood donors at Blood Donor Unit, Indonesian Red Cross in Bandung city, Indonesia.The study is a descriptive and observational with cross sectional design. The study was done at Blood Donor Unit, Indonesian Red Cross in Bandung city from April 2016 to September 2017. The subjects were 142 routine blood donors, blood sampling was done simultaneously with blood donation. Rhesus antigen examination of ethylenediaminetetraacetic acid (EDTA) blood was done by gel method. Subjects characteristics were male (68%) and female (32%), with the mean age was 39 years. Examination of Rhesus antigen were found antigen D(100%), antigen e(98,6%), antigen C(97,9%), antigen c(38,7%) and antigen E(31,7%). Results of Rhesus phenotypes were DCe/DCe(61,3%), DCe/DcE(29,6%), DCe/dce(7%), DcE/DcE(1,4%) and DcE/dce(0.7%). The distribution of Rhesus blood type were affected by factors such as genetics, race, ethnicity, marriage, demography, and migration. Rhesus blood phenotypes proportion in routine blood donors at Blood Donor Unit, Indonesian Red Cross in Bandung city sorted from the most are DCe/DCe, DCe/DcE, DCe/dce, DcE/DcE and DcE/dce.Keywords: blood donor, phenotype, Rhesus

scholarly journals A Cross-Sectional Study of Blood Donors’ Psychological Characteristics over 8 Weeks

2021 ◽  
pp. 1-8
Author(s):  
Max Esefeld ◽  
Ariane Sümnig ◽  
Ulf Alpen ◽  
Hans Jörgen Grabe ◽  
Andreas Greinacher
Keyword(s):  
Blood Donors ◽  
Blood Donation ◽  
Well Being ◽  
Cross Sectional Study ◽  
Psychological Characteristics ◽  
Psychological State ◽  
Structured Interviews ◽  
Negative Effects ◽  
Cross Sectional ◽  
Positive Effects

<b><i>Background:</i></b> Previous studies suggest that blood donation impacts blood donors’ psychological state, with either positive or negative effects, such as feeling more energetic or more exhausted. It has not yet been described how long these effects last. <b><i>Materials and Methods:</i></b> This prospective cohort study consisted of a qualitative and a quantitative part: (1) Psychological characteristics which changed after blood donation were identified by structured interviews of regular whole blood donors (<i>n</i> = 42). Based on this, a questionnaire addressing 7 psychological dimensions was established. (2) The psychological state of 100 blood donors was assessed after blood donation by applying the questionnaire 15–30 min before and during donation, as well as 15–30 min, 6 h, 24 h, 72 h, 1 week, and 8 weeks after donation. The resulting changes were summarized to a score. Furthermore, potential correlations of the score with pre-donation blood pressure, hemoglobin, or body mass index were calculated. <b><i>Results:</i></b> Seven items were identified which changed in at least 25% of blood donors (mood, concentration, satisfaction, resilience, spirit of initiative, physical well-being, energy level). In the 100 blood donors, the well-being score increased (positive effects, <i>n</i> = 23), showed minor changes (<i>n</i> = 53), or decreased (negative effects, <i>n</i> = 24). The positive effects lasted for about 1 week and the negative effects for 3 days. <b><i>Conclusion:</i></b> While the frequency of psychological effects following blood donation identified by our study was comparable to others, the changes of the psychological state in our donors were traceable for a longer period than previously acknowledged.

scholarly journals Knowledge, Attitudes, Practices, and Factors Associated with Voluntary Blood Donation among University Students in Kilimanjaro, Tanzania

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Elionora Elias ◽  
Wilhellmuss Mauka ◽  
Rune N. Philemon ◽  
Damian J. Damian ◽  
Michael J. Mahande ◽  
...  
Keyword(s):  
Young People ◽  
Blood Donors ◽  
Blood Donation ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Attitudes And Practices ◽  
Positive Attitudes ◽  
Willingness To Donate ◽  
The Future ◽  
Donated Blood

Background. Understanding the knowledge and awareness of blood donation among potential blood donors in the population, like young people, and the associated attitudes and practices is important. Methodology. This was a cross-sectional study whereby a self-administered questionnaire was used to collect information from the consenting participants. Results. A total of 422 participants were enrolled. Their mean age was 24.2 (SD 3.6) years. Of the 422, 30% have ever donated blood. 55% of those who had ever donated were repeated blood donors. Majority of the participants (93%) had positive attitudes towards blood donation and 88% were willing to donate in the future. Factors that were significantly associated with ever donating blood were male gender, knowing a person who has donated blood, knowledge of the amount of blood donated, willingness to donate in the future, and not expecting any postdonation reward. Discussion. High awareness, positive attitude, and high intention to donate in the future should be used to underscore the need to educate the young people on the value of blood donation in saving lives and to give them correct information on overall requirements for blood donation.

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