scholarly journals Seroprevalence of Cytomegalovirus among Blood Donor in Transfusion Medicine: Study from Bangladesh

Author(s):  
Dr. Sheikh Saiful Islam Shaheen ◽  
Dr. Md. Ashraful Hoque ◽  
Dr. Jannatul Ferdous

Background: Cytomegalovirus (CMV) infection is a matter for concern among blood bank professionals and blood transfusion recipient, especially in cases of transfusion to neonates and immunocompromised patients. Objective: The aim of the study was to investigate the seroprevalence of cytomegalovirus with the purpose of determining routine CMV screening for donors. Method: A descriptive cross sectional study was carried out in the Department of Transfusion Medicine in Bangabandhu Sheikh Mujib Medical University from January 2017 to December 2017. A total of 150 blood donors were selected by convenient sampling technique. Result: The seroprevalence of cytomegalovirus is 91% for IgG and 4% for IgM. Association was found in between IgG and age,sex.In case of age anti-CMV-IgG,c2= 26.5, t = 9.49; c2> t (Association Exists),for sex anti-CMV-IgG: df = 1, CI = 95%, c2= 17.8, t = 3.84; c2> t (Association Exists)Anti-CMV-IgM: df = 1, CI = 95%, c2= 10.7, t = 3.84; c2> t (Association Exist). This study was undertaken to find out seroprevalence of Cytomegalovirus among blood donors in the department of transfusion medicine. The incidence of cytomegalovirus is 91.3% for IgG and 4% for IgM. Most of the IgG positive subjects were in 38-47 years and for IgM were in 28-37 years. It was observed that seroprevalence of CMV was more in female (94.9% in case of IgG& 6.8% in IgM). It was observed that the highest prevalence of IgG was 3out of 3 (100%)in illiterate and that of IgM was 1 out of 3(33.33%) in illiterate level of education. In conclusion it was found that seroprevalence of cytomegalovirus was 91.3% for IgG and 4% for IgM. Association was found in between IgG & age, sex. Conclusion: Prospective blood donors should be screened for CMV most especially for immunocompromised recipients. Leucoreduced blood products from CMV seronegative donors should be given to preterm neonates, infants as this will prevent transfusion associated perinatal CMV disease. There should be more campaign and awareness on provision of voluntary blood donation for CMV negative blood. Program should be made to create awareness in the community on the significant impact of CMV infection on health.

2019 ◽  
Vol 26 (02) ◽  
Author(s):  
Abdul Aziz Sahto ◽  
Amir Shahzad ◽  
Ruqayya

Objectives: The aim behind this study was assess the frequency of ischemic and hemorrhagic stroke and associated risk factors in patients with hypertension. Study Design: Cross sectional study. Period: One year. Setting: Department of Medicine People’s Medical University, Shaheed Benazeerabad. Material and Methods: This study was a hospital based study in which sampling was done through a purposive sampling technique. A total of 160 patients admitted with stroke were included in our study. After taking informed consent patient’s relevant history and examination were carried out. CT-Scan was done to confirm and different between ischemic and hemorrhagic stroke.SPSS version 17.0 was used to analyze the collected data. Results: Ischemic stroke was observed in 105(66%) patients and 55(34%) were suffered hemorrhagic stroke. Hypertension was 100% in both types of storks in ischemic stroke and hemorrhagic stroke.Rate of diabetes mellitus, dyslipidemia and smoking were significantly high in hemorrhagic stroke than ischemic stroke (p<0.01). Conclusion: We found a high prevalence of ischemic stroke than hemorrhagic stroke in our population. Among associated factors gender, hypertension, dyslipidemia, diabetes and smoking were prevalent in both ischemic and hemorrhagic stroke patients.


2018 ◽  
Vol 25 (08) ◽  
pp. 1245-1251
Author(s):  
Mustansar Billah ◽  
Syed Muhammad Raza Shah ◽  
Muhammad Mujtaba Hashir

Objectives: To determine the frequency of HBV and HCV among blood donorscoming voluntarily at the blood bank of Ibne- Siena hospital and research centre, Multan,Pakistan, to ascertain the disease burden in the community for their future prevention andcontrol. Study Design: It was a descriptive, cross- sectional study on blood units donated byhealthy individuals coming voluntarily for blood donation, and willing to get their blood testedfor HBV, HCV. Setting: Community medicine department of Multan medical and dental collegeMultan, and blood bank of affiliated tertiary hospital, Ibn-e- Siena hospital Multan. Period: Sixmonths period from Jan 2016 to June 2016. Materials and Methods: Data of the blood donorswas collected. Present study was based on previous well maintained records of hospital bloodbank. During the reported period, a total of 1195 blood donors attended the blood bank, andthey all were screened for HBsAg and anti-HCV. SPSS- 16 was used to analyze the data, fordetermination of frequencies of Hepatitis- B, and C according to the age and gender. Results:Total numbers of blood donors were 1195. 1191 were males, and 4 were females. All thefemales were negative for both HBV, and HCV. Males positive for HBV were 18 (1.5 %), andthose Positive for HCV were 27 (3.2%).


2019 ◽  
Vol 26 (04) ◽  
Author(s):  
Ahsan Ashfaq ◽  
KAUSAR ABBAS SALDERA ◽  
AYESHA EJAZ ◽  
NOOR-UN NISA MEMON ◽  
HINA RASHID ◽  
...  

Objectives: To assess serum Neopterin levels in blood donors of local population and to study its relationship with transfusion transmitted infections (TTIs) including syphilis. Study Design: Descriptive cross-sectional study. Place and Duration of Study: This study was carried out in the Department of Physiology LNMC in collaboration with Basic Medical Sciences Institute, (BMSI), and Jinnah Post Graduate Medical Centre (J.P.M.C.) Karachi, from Jan to July 2015.”Methods: Total 174 blood donors were included in the study through random sampling technique. They were screen through the standard procedures used for screening at the JPMC blood bank for WHO recommended diseases. Neopterin was estimated using ELISA. Data analysis was performed using SPSS version 21. Chi square and ANOVA were applied at a confidence level of 95%.”Results: Neopterin level in the sera of syphilis positive blood donors was 5.86 ± 0.78 nmol/l which was within normal range below the cutoff value of 10 nmol/l. Neopterin content in the serum of blood donors who were negative for transfusion transmitted infections was 6.23± 2.19 nmol/l as compared to blood donors testing positive for transfusion transmitted viral infections showing high Neopterin level of 15.10 ± 4.93 nmol/l. (P value 0.001).”Conclusion: Neopterin levels were found to be within normal limits in blood donors testing positive for syphilis However in  blood donors with transfusion transmitted viral infections  serum neopterin levels were elevated.


2020 ◽  
Vol 1 (2) ◽  
pp. 30-41
Author(s):  
Maryam Moula Maryam Moula ◽  
Muhammad Akram Sharif ◽  
Faraz A. Wajidi

To determine employee autonomous motivation and find out the effect of age and Gender on autonomous motivation among employees working in public sector medical university, Karachi. A Cross-sectional study design was used to conduct this study among employees of public sector medical university. The duration of the study was three months. The sample size of the study was 384. The response rate was 78%, 300 out of 384 duly filled questionnaires were collected. A probability random sampling technique was used to collect data. SPSS software was applied to analyze the collected data. Mean ±SD and % & n were explored for Quantitative and Qualitative variables, respectively. T-Test and one-way ANOVA were applied to test hypotheses. P-Value <0.05 was considered significant. 59.3% (n=178) were males. 46% (n=138) were females in age between 25 to 31 years. 53.7 % (n=161) respondent reported their marital status as single. The mean age of the respondents was 30.16±7.03. Factors that motivate employees included salary (34%), positive feedback (26.3%), felt very proud when did well at work (52%), learnt new things (57.7%), , had a feeling of accomplishment (35.3%), Solving work issues made them feel important (26.7%), felt guilty if didn’t accomplish a job-related task (45.3%). The t-test and ANOVA revealed significant effect of gender; t (298) = -2.81, p-value = 0.005, CI [-3.77, -0.66] and age; F (5,294) =2.56, p-Value = 0.027 on employees’ autonomous motivation. It was observed proven that there was a significant effect of gender and age on employee’s autonomous motivation.


2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Kampira Vincent ◽  
Mashasha Maxwell ◽  
Chigidi Esther

Background: Blood is a body fluid responsible for transportation of nutrients, oxygen and metabolic waste. It is a non-pharmaceutical product obtained through voluntary donations. Blood transfusion is very important in the health system of any nation. Patients who are in need of blood donation expect the availability of adequate blood to satisfy their demands. Nevertheless, this is not so, mainly in third world countries like Zimbabwe where less than 6 people donate blood per 1000 populace. We need to deeply understand motivators, possible deterrents and available blood donor knowledge in order to have adequate regular voluntary non-remunerated blood donors. Methods: A cross sectional study of donors incorporating purposive sampling technique was used and a sample size of 465 was used. A self-administered questionnaire was used where donors were rating importance of: factors that motivate or deter their interest to donate blood and rate their blood donation knowledge. Statistical methods were used for reliability and correlation tests. Results: Most of the 465 participants were 1st time donors262(56.3%) and 203(43.7%) had some donation history. All donors endorsed that there exist factors that motivate them to donate blood which included the desire to help someone in need 386 (83%), good attitude of staff 419 (90%), reminders to donate381 (82%) and donor incentives 409 (88%) with their corresponding response rate. Six out of the nine suggested deterrents were endorsed as significant deterrents to blood donation. The corresponding support rate for each deterrent are absence of incentives 529(82%), poor attitude of staff 363(78%), myths and beliefs, 330(71%), feeling bad after donation, 251(54%) and the belief that blood will be sold 330(71%). Most people did not know the minimum age to donate blood as only 54 (11.61%) and only 168(36.13%) knew the correct interval between donations which should be 4 months. Only 171(36.77%) knew that blood expire. Conclusion: Our findings suggest that more donor drives needs to be taken educating people on blood donation, motivating donors to donate whenever there is blood shortage. Young donors are more attracted to concrete items as incentives and females donate more than males. Attitude of staff can motivate or demotivate donors to continue with this altruism gesture.


2021 ◽  
Vol 8 (29) ◽  
pp. 2615-2619
Author(s):  
Indu Pachampully Kumaran ◽  
Archana K.A ◽  
Meena Dharmadas ◽  
Sasikala Nadanganan ◽  
Anu Kumar B ◽  
...  

BACKGROUND Even in the presence of sufficient voluntary blood donors, the need of blood is not met yet. We wanted to evaluate the causes that hinder the smooth functioning of well-maintained blood transfusion services (BTS). METHODS This is a population based cross-sectional study conducted among blood donors from voluntary outreach blood donation camp for period of one year. Total 1536 blood donors from 32 blood donation camps were subjected to study for the sociodemographic characteristic and their knowledge of blood donation. Statistical analysis of data was done using Microsoft Excel, analysed using statistical package for social sciences (SPSS) ver.16 software. RESULTS A total of 32 blood donation camps were conducted during the study period that provided 1536 donors. In most of the camps, male donors (75 %) were more than female donors. Donors of age group of 30 to 39 years (43.9 %) were more when compared to others. Donors those who were married accounted for 79.9 %. Blood donors of Hindu religion (53 %) were more. CONCLUSIONS The main hindrance for blood donor motivation is lack of knowledge. Literacy and chance to mingle in society have a positive effect on blood donor motivation. Targeting of effective donor motivation, recruitment, and retention were attained by conducting awareness classes, seminars, workshops, and visual communication modalities. KEYWORDS World Health Organization, Altruistic Blood Donor, Blood Transfusion Services, Transfusion Transmitted Infections, Blood Components and Plasma Derivatives, Director General of Health Services (DGHS), National Blood Transportation Council (NBTC)


2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Adelbert B. James ◽  
Cassandra D. Josephson ◽  
Marta I. Castillejo ◽  
George B. Schreiber ◽  
John D. Roback

Background. The explosive growth of Hispanics in the US makes this population a significant and untapped source for blood donation. Methods. A cross-sectional study was performed to evaluate blood donation behaviors and demographics of foreign-born and US-born Hispanic donors between 2006 and 2009 in metropolitan Atlanta, GA, USA. Bivariate analyses and multivariate logistic regression were used to assess factors associated with foreign-born donors. Results. 5,119 foreign-born and 11,841 US-born Hispanics donated blood. Foreign-born Hispanic donors were more likely than US-born donors to be blood group O (57.6% versus 52.0%; P<.001) and more frequent donors (2.2 versus 2.0; P<.001). Cuban-born donors had the highest rates of return donation (63.2%). In contrast, Mexicans, the most prevalent subpopulation among foreign-born Hispanic donors (31.8%), had the lowest rates of return donation (42.0%). Conclusions. The heterogeneity found among Hispanic donors in this study is valuable for the design of recruitment strategies to increase blood donations.


2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Najd Alfouzan

Background. Blood donation is remarkably safe medical procedure. However, attitudes, beliefs, and level of knowledge may affect it. Objectives. To measure the level of knowledge regarding blood donation, find out positive and negative attitudes, identify the obstacles, and suggest some motivational factors. Methodology. A cross-sectional study was conducted at King Abdulaziz Medical City (KAMC). Participants were selected by convenient nonrandom sampling technique. A self-created questionnaire was used for data collection. Results. The study included 349 individuals. About 45.8% of the participants claimed that they have a history of blood donation. Reported causes for not donating blood were blood donation not crossing their mind (52.4%), no time for donation (45%), and difficulty in accessing blood donation center (41.3%). Reported motivating factors for donating blood were one day off (81.4%), mobile blood donation caravans in public areas (79.1%), token gifts (31.5%), and finally paying money (18.9%). Conclusion. People in the age group 31–50 years, males, higher education and military were more likely to donate blood as well as People who showed higher knowledge level and positive attitude towards blood donation. More educational programs to increase the awareness in specific targeted populations and also to focus on some motivational factors are recommended.


Author(s):  
Emiliana Eusebio-Ponce ◽  
Francisco Javier Candel ◽  
Robert Paulino-Ramirez ◽  
Irene Serrano-García ◽  
Eduardo Anguita ◽  
...  

Objectives. Being a Caribbean country, the Dominican Republic is considered endemic for HTLV-1. Viral screening in blood banks is recommended for this blood borne infection. The purpose of this work is to analyze the seroprevalence and trends of HTLV-1/2 in the Dominican Republic blood donors; it is focused on Santo Domingo, the capital of the country, which has the largest blood donation activity. We also aim at comparing our findings with published data from neighboring countries. Patients and methods. We performed a retrospective cross-sectional study of 10 blood centers of Santo Domingo, which reported HTLV and the other blood-transmitted infections in full. They represent more than 40% of the province’s blood donations. Annual seroprevalence of HTLV-1/2, period prevalence (2012-2017), and time trend were determined. Results. A total of 352,960 blood donations were evaluated. The HTLV-1/2 period prevalence was 0.26% (929/352,960)(95% CI: 0.24–0.28%). We also found a marked predominance of replacement donation (90.4%) in comparison to voluntary contributions (9.6%). Therefore, this blood donor study may provide clues on the general prevalence of the infection. Conclusions. Seroprevalence of HTLV-1/2 in blood donors of Santo Domingo, Dominican Republic, showed a relatively low and steady trend in the studied period.


2020 ◽  
Vol 3 (1) ◽  
pp. 43-50
Author(s):  
Syarifah Fazhilah Djamalilleil ◽  
Rosmaini Rosmaini ◽  
Nadia Purnama Dewi

Introduction: The lack of concern toward sleep quality is frequently found on students of high schoold, hectic workers and college students, the impacts of sleep lack could affect to learning concentration. Aims: To find out the correlation between sleep quality and learning concentration ,students of medical faculty, University of Baiturrahmah Padang in Second Year.Method: The scope of this study covers the field of general medical science, this study was conducted at the Faculty of Medical, University of Baiturahmah Padang on April 2019 to January 2020. The type of this study was descriptive analytic study with cross sectional study design. Affordable population in the study were students of the Faculty of Medical, University of Baiturahmah in second year, the amount was 150 people with 76 samples by using random sampling technique. Univariate data analysis was presented in the form of frequency and percentage distributions as well as bivariate analysis using chi-square test and data processing using computerized SPSS program version 24.0. Result: Based on the results of the study, People who had the poor sleep quality are 53 people (69.7%), had a poor learning concentration are 42 people (55.3%) and there was a correlation between sleep quality and learning concentration of students at the Faculty of Medical, University of Baiturrahmah, Padang in second year P = 0.034 <0.05.Conclusion: It is proven that there was a correlation between sleep quality and the learning concentration of students at the Faculty of Medical, University of Baiturrahmah Padang, Second year.


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