Effects of Transport and Altitude on Hormones and Oxidative Stress Parameters in Sheep

AbstractWith this study, it was aimed to determine the stress effects that can be caused by transporting and altitude in sheep. Karayaka sheep were used in the study. The live weight of the sheep (n=30) while hungry was determined before transport and sea level. Average live weight was determined as 55.64 ± 4.66 kg. Blood samples were collected just before (sea level) and just after transport (1500 meters above sea level). Transportation distance was approximately 182 km and duration was 5 hours. According to the findings, cortisol was not affected by transport stress and altitude (p>0.05) and Triiyodotironin (T3) (p<0.039) and Tyrosine (T4) (p<0.000) were affected significantly. Malondialchehyche (MDA), which is one of the oxidative stress parameters, was significantly affected (p<0.039) and Protein Carbonyl (PC) values were not affected by transport and altitude (p>0.184). As a result of this study, it was determined that transportation and altitude in sheep causes stress. Stress-reducing measures should be taken in the exposure of sheep to altitude differences and in transportation. Antioxidant nutritional supplements should be made in order not to negatively affect the meat quality in sheep.

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Effects of transport and altitude on hormones and oxidative stress parameters in sheep

PLoS ONE ◽

10.1371/journal.pone.0244911 ◽

2021 ◽

Vol 16 (2) ◽

pp. e0244911

Author(s):

Hilal Tozlu Çelik ◽

Fatih Ahmet Aslan ◽

Diler Us Altay ◽

Metehan Eser Kahveci ◽

Kalbiye Konanç ◽

...

Keyword(s):

Oxidative Stress ◽

Sea Level ◽

Meat Quality ◽

Live Weight ◽

Protein Carbonyl ◽

The Black Sea ◽

Black Sea Region ◽

Stress Effects ◽

Oxidative Stress Parameters ◽

Stress Parameters

In study, it was aimed to determine the stress effects that can be caused by transporting and altitude in sheep. Karayaka sheeps were used in the study. Karayaka sheeps are a valuable breed of meat quality and fleece, which is raised in the Black Sea region. The live weight of the sheep (n = 30) while hungry was determined before transport and sea level. Average live weight was determined as 55.64 ± 4.66 kg. Blood samples were collected just before (sea level) and just after transport (1500 meters above sea level). Transportation distance was approximately 182 km and duration was 5 hours. According to the findings, cortisol was not affected by transport stress and altitude (P>0.05) and Triiyodotironin (T3) (P<0.039) and Tyrosine (T4) (P<0.000) were affected significantly. Malondialchehyche (MDA), which is one of the oxidative stress parameters, was significantly affected (P<0.039) and Protein Carbonyl (PC) values were not affected by transport and altitude (P>0.184). As a result of this study, it was determined that transportation and altitude in sheep causes stress. Stress-reducing measures should be taken in the exposure of sheep to altitude differences and in transportation. Antioxidant nutritional supplements should be made in order not to negatively affect the meat quality in sheep.

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Omega-3 fatty acids and mood stabilizers alter behavioral and oxidative stress parameters in animals subjected to fenproporex administration

Metabolic Brain Disease ◽

10.1007/s11011-016-9942-7 ◽

2016 ◽

Vol 32 (2) ◽

pp. 519-528 ◽

Cited By ~ 2

Author(s):

Lara M. Gomes ◽

Milena Carvalho-Silva ◽

Letícia J. Teixeira ◽

Joyce Rebelo ◽

Isabella T. Mota ◽

...

Keyword(s):

Oxidative Stress ◽

Fatty Acids ◽

Mood Stabilizers ◽

Omega 3 Fatty Acids ◽

Omega 3 ◽

Oxidative Stress Parameters ◽

And Oxidative Stress ◽

Stress Parameters

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Behavior and oxidative stress parameters in rats subjected to the animal's models induced by chronic mild stress and 6-hydroxydopamine

Behavioural Brain Research ◽

10.1016/j.bbr.2021.113226 ◽

2021 ◽

Vol 406 ◽

pp. 113226

Author(s):

Talita Tuon ◽

Sandra S. Meirelles ◽

Airam B. de Moura ◽

Thayse Rosa ◽

Laura A. Borba ◽

...

Keyword(s):

Oxidative Stress ◽

Chronic Mild Stress ◽

Mild Stress ◽

Oxidative Stress Parameters ◽

6 Hydroxydopamine ◽

And Oxidative Stress ◽

Stress Parameters

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Conjugated Linoleic Acid-Curcumin Attenuates Cognitive Deficits and Oxidative Stress Parameters in the Ethidium Bromide–Induced Model of Demyelination

Neurotoxicity Research ◽

10.1007/s12640-020-00310-0 ◽

2021 ◽

Author(s):

Behnaz Barzegarzadeh ◽

Homeira Hatami ◽

Gholamreza Dehghan ◽

Nazli Khajehnasiri ◽

Mehdi Khoobi ◽

...

Keyword(s):

Oxidative Stress ◽

Linoleic Acid ◽

Conjugated Linoleic Acid ◽

Ethidium Bromide ◽

Cognitive Deficits ◽

Oxidative Stress Parameters ◽

And Oxidative Stress ◽

Stress Parameters

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Protective role of Sterculia tragacantha aqueous extract on pancreatic gene expression and oxidative stress parameters in streptozotocin-induced diabetic rats

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2021-0020 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Basiru Olaitan Ajiboye ◽

Babatunji Emmanuel Oyinloye ◽

Jennifer Chidera Awurum ◽

Sunday Amos Onikanni ◽

Adedotun Adefolalu ◽

...

Keyword(s):

Oxidative Stress ◽

Body Weight ◽

Protective Role ◽

Diabetic Rats ◽

Gene Expressions ◽

Ki 67 ◽

Oxidative Stress Parameters ◽

And Oxidative Stress ◽

Stress Parameters

Abstract Objectives The current study evaluates the protective role of aqueous extract of Sterculia tragacantha leaf (AESTL) on pancreatic gene expressions (insulin, PCNA, PDX-1, KI-67 and GLP-1R) and oxidative stress parameters in streptozotocin-induced diabetic rats. Methods Diabetes mellitus was induced into the experimental Wistar animals via intraperitoneal (IP) injection of streptozotocin (35 mg/kg body weight) and 5% glucose water was given to the rats for 24 h after induction. The animals were categorized into five groups of 10 rats each as follows normal control, diabetic control, diabetic rats administered AESTL (150 and 300 mg/kg body weight) and diabetic rats administered metformin (200 mg/kg) orally for two weeks. Thereafter, the animals were euthanized, blood sample collected, pancreas harvested and some pancreatic gene expressions (such as insulin, PCNA, PDX-1, KI-67, and GLP-1R)s as well as oxidative stress parameters were analyzed. Results The results revealed that AESTL significantly (p<0.05) reduced fasting blood glucose level, food and water intake, and lipid peroxidation in diabetic rats. Diabetic rats administered different doses of AESTL showed a substantial upsurge in body weight, antioxidant enzyme activities, and pancreatic gene expressions (insulin, PCNA, PDX-1, KI-67, and GLP-1R). Conclusions It can therefore be concluded that AESTL has the ability to protect the pancreas during diabetes mellitus conditions.

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Dopamine Gene Polymorphism, Biochemical and Oxidative Stress Parameters in Geriatric Population with and Without Depression: A Pilot Study

Indian Journal of Clinical Biochemistry ◽

10.1007/s12291-020-00928-z ◽

2021 ◽

Author(s):

Raza Abbas Mahdi ◽

Israr Ahmad ◽

Talha Jilani ◽

Jamal Akhtar Ansari ◽

Farzana Mahdi ◽

...

Keyword(s):

Oxidative Stress ◽

Pilot Study ◽

Gene Polymorphism ◽

Geriatric Population ◽

Oxidative Stress Parameters ◽

And Oxidative Stress ◽

Stress Parameters

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The Influence of Probiotic Supplementation on Depressive Symptoms, Inflammation, and Oxidative Stress Parameters and Fecal Microbiota in Patients with Depression Depending on Metabolic Syndrome Comorbidity—PRO-DEMET Randomized Study Protocol

Journal of Clinical Medicine ◽

10.3390/jcm10071342 ◽

2021 ◽

Vol 10 (7) ◽

pp. 1342

Author(s):

Oliwia Gawlik-Kotelnicka ◽

Anna Skowrońska ◽

Aleksandra Margulska ◽

Karolina H. Czarnecka-Chrebelska ◽

Igor Łoniewski ◽

...

Keyword(s):

Oxidative Stress ◽

Metabolic Syndrome ◽

Study Protocol ◽

Bifidobacterium Longum ◽

White Blood Cells ◽

Fecal Microbiota ◽

Probiotic Supplementation ◽

Oxidative Stress Parameters ◽

And Oxidative Stress ◽

Stress Parameters

There is a huge need to search for new treatment options and potential biomarkers of therapeutic response to antidepressant treatment. Depression and metabolic syndrome often coexist, while a pathophysiological overlap, including microbiota changes, may play a role. The paper presents a study protocol that aims to assess the effect of probiotic supplementation on symptoms of depression, anxiety and stress, metabolic parameters, inflammatory and oxidative stress markers, as well as fecal microbiota in adult patients with depressive disorders depending on the co-occurrence of metabolic syndrome. The trial will be a four-arm, parallel-group, prospective, randomized, double-blind, controlled design that will include 200 participants and will last 20 weeks (ClinicalTrials.gov identifier: NCT04756544). The probiotic preparation will contain Lactobacillus helveticus Rosell®-52, Bifidobacterium longum Rosell®-175. We will assess the level of depression, anxiety and stress, quality of life, blood pressure, body mass index and waist circumference, white blood cells count, serum levels of C-reactive protein, high-density lipoprotein (HDL) cholesterol, triglycerides, fasting glucose, fecal microbiota composition and the level of some fecal microbiota metabolites, as well as serum inflammatory markers and oxidative stress parameters. The proposed trial may establish a safe and easy-to-use adjunctive treatment option in a subpopulation of depressive patients only partially responsive to pharmacologic therapy.

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