scholarly journals Effects of worldwide interventions and vaccination on COVID-19 between waves and countries

2021 ◽  
Author(s):  
Yong Ge ◽  
Wenbin Zhang ◽  
Haiyan Liu ◽  
Corrine W Ruktanonchai ◽  
Maogui Hu ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Large Scale ◽  
International Travel ◽  
Spatiotemporal Variations ◽  
School Closures ◽  
Vaccination Strategies ◽  
Travel Restrictions ◽  
The Impact ◽  
Second Wave ◽  
Pharmaceutical Interventions

Worldwide governments have rapidly deployed non-pharmaceutical interventions (NPIs) to mitigate the COVID-19 pandemic, together with the large-scale rollout of vaccines since late 2020. However, the effect of these individual NPI and vaccination measures across space and time has not been sufficiently explored. By the decay ratio in the suppression of COVID-19 infections, we investigated the performance of different NPIs across waves in 133 countries, and their integration with vaccine rollouts in 63 countries as of 25 March 2021. The most effective NPIs were gathering restrictions (contributing 27.83% in the infection rate reductions), facial coverings (16.79%) and school closures (10.08%) in the first wave, and changed to facial coverings (30.04%), gathering restrictions (17.51%) and international travel restrictions (9.22%) in the second wave. The impact of NPIs had obvious spatiotemporal variations across countries by waves before vaccine rollouts, with facial coverings being one of the most effective measures consistently. Vaccinations had gradually contributed to the suppression of COVID-19 transmission, from 0.71% and 0.86% within 15 days and 30 days since Day 12 after vaccination, to 1.23% as of 25 March 2021, while NPIs still dominated the pandemic mitigation. Our findings have important implications for continued tailoring of integrated NPI or NPI-vaccination strategies against future COVID-19 waves or similar infectious diseases.

scholarly journals Effects of worldwide interventions and vaccination on COVID-19 between waves and countries

2021 ◽  
Author(s):  
Yong Ge ◽  
Wenbin Zhang ◽  
Haiyan Liu ◽  
Corrine W Ruktanonchai ◽  
Maogui Hu ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Large Scale ◽  
International Travel ◽  
Spatiotemporal Variations ◽  
School Closures ◽  
Vaccination Strategies ◽  
Travel Restrictions ◽  
The Impact ◽  
Second Wave ◽  
Pharmaceutical Interventions

Abstract Worldwide governments have rapidly deployed non-pharmaceutical interventions (NPIs) to mitigate the COVID-19 pandemic, together with the large-scale rollout of vaccines since late 2020. However, the effect of these individual NPI and vaccination measures across space and time has not been sufficiently explored. By the decay ratio in the suppression of COVID-19 infections, we investigated the performance of different NPIs across waves in 133 countries, and their integration with vaccine rollouts in 63 countries as of 25 March 2021. The most effective NPIs were gathering restrictions (contributing 27.83% in the infection rate reductions), facial coverings (16.79%) and school closures (10.08%) in the first wave, and changed to facial coverings (30.04%), gathering restrictions (17.51%) and international travel restrictions (9.22%) in the second wave. The impact of NPIs had obvious spatiotemporal variations across countries by waves before vaccine rollouts, with facial coverings being one of the most effective measures consistently. Vaccinations had gradually contributed to the suppression of COVID-19 transmission, from 0.71% and 0.86% within 15 days and 30 days since Day 12 after vaccination, to 1.23% as of 25 March 2021, while NPIs still dominated the pandemic mitigation. Our findings have important implications for continued tailoring of integrated NPI or NPI-vaccination strategies against future COVID-19 waves or similar infectious diseases.

scholarly journals Measuring the impact of suspending Umrah, a global mass gathering in Saudi Arabia on the COVID-19 pandemic

2021 ◽  
Author(s):  
Sultanah M. Alshammari ◽  
Waleed K. Almutiry ◽  
Harsha Gwalani ◽  
Saeed M. Algarni ◽  
Kawther Saeedi
Keyword(s):  
Saudi Arabia ◽  
International Travel ◽  
Modern World ◽  
Mass Gatherings ◽  
Preventative Measures ◽  
Rapid Spread ◽  
Travel Restrictions ◽  
The Impact ◽  
Travel Restriction ◽  
Pharmaceutical Interventions

AbstractSince the early days of the coronavirus (COVID-19) outbreak in Wuhan, China, Saudi Arabia started to implement several preventative measures starting with the imposition of travel restrictions to and from China. Due to the rapid spread of COVID-19, and with the first confirmed case in Saudi Arabia in March 2019, more strict measures, such as international travel restriction, and suspension or cancellation of major events, social gatherings, prayers at mosques, and sports competitions, were employed. These non-pharmaceutical interventions aim to reduce the extent of the epidemic due to the implications of international travel and mass gatherings on the increase in the number of new cases locally and globally. Since this ongoing outbreak is the first of its kind in the modern world, the impact of suspending mass gatherings on the outbreak is unknown and difficult to measure. We use a stratified SEIR epidemic model to evaluate the impact of Umrah, a global Muslim pilgrimage to Mecca, on the spread of the COVID-19 pandemic during the month of Ramadan, the peak of the Umrah season. The analyses shown in the paper provide insights into the effects of global mass gatherings such as Hajj and Umrah on the progression of the COVID-19 pandemic locally and globally.

scholarly journals Adoption and impact of non-pharmaceutical interventions for COVID-19

2020 ◽  
Vol 5 ◽  
pp. 59 ◽  
Author(s):  
Natsuko Imai ◽  
Katy A.M. Gaythorpe ◽  
Sam Abbott ◽  
Sangeeta Bhatia ◽  
Sabine van Elsland ◽  
...  
Keyword(s):  
Mitigation Strategies ◽  
Control Measures ◽  
School Closures ◽  
Geographic Spread ◽  
Travel Restrictions ◽  
Influenza Transmission ◽  
Societal Impacts ◽  
Government Websites ◽  
The Impact ◽  
Pharmaceutical Interventions

Background: Several non-pharmaceutical interventions (NPIs) have been implemented across the world to control the coronavirus disease (COVID-19) pandemic. Social distancing (SD) interventions applied so far have included school closures, remote working and quarantine. These measures have been shown to have large impacts on pandemic influenza transmission. However, there has been comparatively little examination of such measures for COVID-19. Methods: We examined the existing literature, and collated data, on implementation of NPIs to examine their effects on the COVID-19 pandemic so far. Data on NPIs were collected from official government websites as well as from media sources. Results: Measures such as travel restrictions have been implemented in multiple countries and appears to have slowed the geographic spread of COVID-19 and reduced initial case numbers. We find that, due to the relatively sparse information on the differences with and without interventions, it is difficult to quantitatively assess the efficacy of many interventions. Similarly, whilst the comparison to other pandemic diseases such as influenza can be helpful, there are key differences that could affect the efficacy of similar NPIs. Conclusions: The timely implementation of control measures is key to their success and must strike a balance between early enough application to reduce the peak of the epidemic and ensuring that they can be feasibly maintained for an appropriate duration. Such measures can have large societal impacts and they need to be appropriately justified to the population. As the pandemic of COVID-19 progresses, quantifying the impact of interventions will be a vital consideration for the appropriate use of mitigation strategies.

scholarly journals Role of Transport during Outbreak of Infectious Diseases: Evidence from the Past

2020 ◽  
Vol 12 (18) ◽  
pp. 7367 ◽  
Author(s):  
Deepti Muley ◽  
Md. Shahin ◽  
Charitha Dias ◽  
Muhammad Abdullah
Keyword(s):  
Infectious Diseases ◽  
Traffic Safety ◽  
International Travel ◽  
Protective Measure ◽  
Transport Sector ◽  
Outdoor Activities ◽  
Travel Restrictions ◽  
Mode Share ◽  
Spread Of Infection ◽  
The Impact

The outbreak of infectious diseases affects people’s lifestyles significantly, as they undertake fewer outdoor activities as a protective measure and to follow government orders of restricted movements. This paper reviewed the scientific literature related to transport and infectious diseases to gain insights into managing such circumstances. The outcomes indicate that the transport sector has a two-fold role during the outbreak of infectious diseases: controlling the spread of infection and assessing the impact of reduced outdoor activities on the transport sector. It was found that local and international travel restrictions, if applied at the initial stages, are effective in controlling the spread of infectious disease; at a later stage, behavioral changes become prominent in limiting the spread. Further, the outbreaks resulted in a significant reduction in mobility, altering traffic patterns with lower peaks and improving traffic safety. The public transport mode share reduced considerably and people preferred cars and active modes. These changes also showed positive impacts on air pollution and water pollution. Further, the air transport and tourism sector were noted to be the hardest hit and will recover slowly. The outcomes from the review will be useful for planners and administrators in managing future emergency conditions better.

scholarly journals UNWTO World Tourism Barometer and Statistical Annex, October 2020

2020 ◽  
Vol 18 (6) ◽  
pp. 1-36 ◽  
Keyword(s):  
The United States ◽  
International Travel ◽  
International Tourism ◽  
The European Union ◽  
International Tourist ◽  
The Pacific ◽  
Slow Virus ◽  
Travel Restrictions ◽  
Main Barrier ◽  
The Impact

International travel plunges 70% in the first eight months of 2020 International tourist arrivals (overnight visitors) declined 70% in the first eight months of 2020 over the same period of last year, amid global travel restrictions including many borders fully closed, to contain the ongoing COVID-19 pandemic. International arrivals plunged 81% in July and 79% in August, traditionally the two busiest months of the year and the peak of the Northern Hemisphere summer season. Despite such large declines, this represents a relative improvement over the 90% or greater decreases of the previous months, as some destinations started to reopen to international tourism, mostly in the European Union. The decline in January-August 2020 represents 700 million fewer international tourist arrivals compared to the same period in 2019, and translates into a loss of US$ 730 billion in export revenues from international tourism, more than 8 times the loss in 2009 under the impact of the global economic crisis. Asia and the Pacific, the first region to suffer the impact of the pandemic, saw a 79% decrease in arrivals in January-August 2020. Africa and the Middle East both recorded a 69% drop this eight-month period, while Europe saw a 68% decline and the Americas 65%. Data on international tourism expenditure continues to reflect very weak demand for outbound travel, though in several large markets such as the United States, Germany and Italy there is a small uptick in spending in the months of July and August. Based on latest trends, a 75% decrease in international arrivals is estimated for the month of September and a drop of close to 70% for the whole of 2020. While demand for international travel remains subdued, domestic tourism is strengthening recovery in several large markets such as China and Russia. The UNWTO Confidence Index continues at record lows. Most UNWTO Panel Experts expect a rebound in international tourism by the third quarter of 2021 and a return to pre-pandemic 2019 levels not before 2023. Experts consider travel restrictions as the main barrier weighing on the recovery of international tourism, along with slow virus containment and low consumer confidence.

scholarly journals Modelling transmission and control of the COVID-19 pandemic in Australia

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Sheryl L. Chang ◽  
Nathan Harding ◽  
Cameron Zachreson ◽  
Oliver M. Cliff ◽  
Mikhail Prokopenko
Keyword(s):  
Computational Simulation ◽  
International Travel ◽  
School Closures ◽  
Agent Based ◽  
Social Distancing ◽  
Fine Grained ◽  
Trade Offs ◽  
Travel Restrictions ◽  
High Level ◽  
And Control

Abstract There is a continuing debate on relative benefits of various mitigation and suppression strategies aimed to control the spread of COVID-19. Here we report the results of agent-based modelling using a fine-grained computational simulation of the ongoing COVID-19 pandemic in Australia. This model is calibrated to match key characteristics of COVID-19 transmission. An important calibration outcome is the age-dependent fraction of symptomatic cases, with this fraction for children found to be one-fifth of such fraction for adults. We apply the model to compare several intervention strategies, including restrictions on international air travel, case isolation, home quarantine, social distancing with varying levels of compliance, and school closures. School closures are not found to bring decisive benefits unless coupled with high level of social distancing compliance. We report several trade-offs, and an important transition across the levels of social distancing compliance, in the range between 70% and 80% levels, with compliance at the 90% level found to control the disease within 13–14 weeks, when coupled with effective case isolation and international travel restrictions.

scholarly journals Closed, Bused, Mixed: A Literature Review on the Impact of Rural School Closure; Effects of Busing on Rural Students; and Student Performance in Small Schools and Mixed-Age Classes

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Tatiana Zakharova
Keyword(s):  
Literature Review ◽  
Student Performance ◽  
Rural Schools ◽  
Large Scale ◽  
Small Schools ◽  
Rural School ◽  
School Closure ◽  
Rural Students ◽  
School Closures ◽  
The Impact

In 2000, Lauzon and Leahy completed a literature review on rural schools and educational reform, concluding that rural schools were indeed worth saving. In 2017, I conducted a literature review with the goal of offering an update to that article, investigating the post-2001 research on the impact of rural school closures; the effects of bussing of rural students to/from school; and student performance in small schools and mixed-grade classes. The results were mixed and contradictory, equal in their puzzling to the complexity of defining what is “rural” and what is “small school”. While some of the researchers continue to point out the unique place of local schools in rural settings, many also note the lack of large-scale studies into the impact of rural school closures, especially the impact on students – even "who pays and the price they pay, is always of interest" (bell hooks)… or is it?

scholarly journals ЮНВТО Всемирная туристская Барометр, и статистическое приложение Обновленная информация, Декабрь 2020 года

2020 ◽  
Vol 18 (7) ◽  
pp. 1-36
Keyword(s):  
Travel Demand ◽  
Economic Loss ◽  
The United States ◽  
International Travel ◽  
International Tourism ◽  
Current Trends ◽  
International Tourist ◽  
The Pacific ◽  
Travel Restrictions ◽  
The Impact

International tourism expected to decline over 70% in 2020, back to levels of 30 years ago International tourist arrivals (overnight visitors) fell by 72% in January-October 2020 over the same period last year, curbed by slow virus containment, low traveller confidence and important restrictions on travel still in place, due to the COVID-19 pandemic. The decline in the first ten months of the year represents 900 million fewer international tourist arrivals compared to the same period in 2019, and translates into a loss of US$ 935 billion in export revenues from international tourism, more than 10 times the loss in 2009 under the impact of the global economic crisis. Asia and the Pacific saw an 82% decrease in arrivals in January-October 2020. The Middle East recorded a 73% decline, while Africa saw a 69% drop this ten-month period. International arrivals in both Europe and the Americas declined by 68%. Data on international tourism expenditure continues to reflect very weak demand for outbound travel. However, some large markets such as the United States, Germany and France have shown some shy signs of recovery in the recent months. While demand for international travel remains subdued, domestic tourism continues to grow in several large markets such as China and Russia, where domestic air travel demand has mostly returned to pre-COVID levels. Based on current trends, UNWTO expects international arrivals to decline by 70% to 75% for the whole of 2020. This would mean that international tourism could have returned to levels of 30 years ago. The estimated decline in internationals tourism in 2020 is equivalent to a loss of about 1 billion arrivals and US$ 1.1 trillion in international tourism receipts. This plunge in international tourism could result in an estimated economic loss of over US$ 2 trillion in global GDP, more than 2% of the world’s GDP in 2019. Looking ahead, the announcement and the roll-out of a vaccine are expected to gradually increase consumer confidence and contribute to ease travel restrictions. UNWTO’s extended scenarios for 2021-2024 point to a rebound in international tourism by the second half of 2021. Nonetheless, a return to 2019 levels in terms of international arrivals could take 2½ to 4 years.

scholarly journals Predicting the impact of asymptomatic transmission, non-pharmaceutical intervention and testing on the spread of COVID19

2020 ◽  
Author(s):  
Ira B. Schwartz ◽  
James Kaufman ◽  
Kun Hu ◽  
Simone Bianco
Keyword(s):  
Predictive Models ◽  
Health Interventions ◽  
Strong Impact ◽  
Public Health Interventions ◽  
Removal Time ◽  
The Impact ◽  
Second Wave ◽  
Pharmaceutical Interventions ◽  
Epidemiological Parameters ◽  
Disease Testing

AbstractWe introduce a novel mathematical model to analyze the effect of removing non-pharmaceutical interventions on the spread of COVID19 as a function of disease testing rate. We find that relaxing interventions has a strong impact on the size of the epidemic peak as a function of intervention removal time. We show that it is essential for predictive models to explicitly capture transmission from asymptomatic carriers and important to obtain precise information on asymptomatic transmission by testing. The asymptomatic reservoir, reported to account for as much as 85% of transmission, will contribute to resurgence of the epidemic if public health interventions are removed too soon. Use of more basic models that fail to capture asymptomatic transmission can result in large errors in predicted clinical caseload or in fitted epidemiological parameters and, therefore, may be unreliable in estimating the risk of a second wave based on the timing of terminated interventions.

scholarly journals A viral perspective on worldwide non-pharmaceutical interventions against COVID-19

2020 ◽  
Author(s):  
Jean-Philippe Rasigade ◽  
Anaïs Barray ◽  
Julie Teresa Shapiro ◽  
Charlène Coquisart ◽  
Yoann Vigouroux ◽  
...  
Keyword(s):  
Large Scale ◽  
Reproduction Number ◽  
Cumulative Effect ◽  
Epidemiological Data ◽  
Time And Space ◽  
Minimal Set ◽  
Genomic Divergence ◽  
The Impact ◽  
Pharmaceutical Interventions

AbstractQuantifying the effectiveness of large-scale non-pharmaceutical interventions (NPIs) against COVID-19 is critical to adapting responses against future waves of the pandemic. Most studies of NPIs thus far have relied on epidemiological data. Here, we report the impact of NPIs on the evolution of SARS-CoV-2, taking the perspective of the virus. We examined how variations through time and space of SARS-CoV-2 genomic divergence rates, which reflect variations of the epidemic reproduction number Rt, can be explained by NPIs and combinations thereof. Based on the analysis of 5,198 SARS-CoV-2 genomes from 57 countries along with a detailed chronology of 9 non-pharmaceutical interventions during the early epidemic phase up to May 2020, we find that home containment (35% Rt reduction) and education lockdown (26%) had the strongest predicted effectiveness. To estimate the cumulative effect of NPIs, we modelled the probability of reducing Rt below 1, which is required to stop the epidemic, for various intervention combinations and initial Rt values. In these models, no intervention implemented alone was sufficient to stop the epidemic for Rt’s above 2 and all interventions combined were required for Rt’s above 3. Our approach can help inform decisions on the minimal set of NPIs required to control the epidemic depending on the current Rt value.

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