scholarly journals Seroprevalence of COVID-19 in HIV Population

Author(s):  
Shivdas Rajaram Naik ◽  
Swasthi S Kumar ◽  
Ankit Mittal ◽  
Satish Swain ◽  
Sanjay Ranjan ◽  
...  

Background: seroprevalence helps us to estimate the exact prevalence of a disease in a population. More than a year since the identification of the disease, it is still not known the exact burden of the disease in the PLHA group. Seroprevalence data in this subset of the population is scarce in most part of the world, including India. The current study aimed to estimate the seroprevalence of anti-SARS-CoV-2 IgG antibody among people living with HIV/AIDS. Aim: To determine the seroprevalence of SARS-CoV-2 antibodies in PLHA (People living with HIV/AIDS). Design: This was an observational prospective cohort study. Method: This cross-sectional study, conducted at a tertiary care hospital in North India, recruited HIV positive patients following at the ART centre of the institute. Anti-SARS-CoV-2 IgG antibody levels targeting recombinant spike receptor-binding domain (RBD) protein of SARS CoV-2 were estimated in serum sample by the chemiluminescent immunoassay method. Results: A total of 164 patients were recruited in the study with mean age (+SD) of 41.2 (+15.4) years and 55% male population. Positive serology against SARS CoV-2 was detected in 14% patients (95% C 9.1-20.3%). Conclusion: The seroprevalence of COVID-19 disease in PLHA was found to be lower than the general population.

Author(s):  
Sumit Lathwal ◽  
Saurabh Mahajan ◽  
Arun K. Yadav

Background: Disclosure is a planned and selective behavior that responds to the balance of potential risks and benefits of secrecy and disclosure of the person living with HIV. The disclosure of HIV status to sexual partners, family or friends, has been shown to be a potent stressor, as persons living with HIV/AIDS might fear negative reactions such as blame, rejection or violence. This study was carried out with an aim to study the patterns of HIV status disclosure and the problems related with it among the HIV positive patients admitted in a tertiary care hospital in Western Maharashtra.Methods: A cross-sectional descriptive, hospital based study carried out in a tertiary care hospital of Western Maharashtra from 01 October 2008 to 30 September 2010. A total of 92 consenting respondents admitted in the hospital were administered a pre tested semi-structured questionnaire to collect the data. The results were analysed using SPSS Ver 16.0.Results: Out of 74 married HIV positive individuals who had a chance to disclose their sero-status to spouse, 64 (86.5%, 95% CI-78.7% to 94.29%) voluntarily disclosed their HIV status to spouse while a small number i.e. 10 (13.5%, 95% CI- 05.71% to 21.29%) did not disclose their HIV status to spouse.Conclusions: This exploratory analysis suggests the need for tailoring interventions for improving disclosure decisions making and outcomes. Institutionalized measures need to be enforced judiciously to assist the HIV positive individuals to reveal their status to their wife and other members of their social group.


Author(s):  
S. Cynthia Subhaprada ◽  
Shasank R. V. S. S. ◽  
T. Sivakala ◽  
S. Madhusai

Background: HIV/AIDS is known to affect an individual not only physically but also mentally, socially, and financially. It is a syndrome that builds a vacuum in a person affecting his/her life as a whole. Combined with ART, Quality of life (QoL) is an important component in the evaluation of the wellbeing of people living with HIV/AIDS (PLHIV). The objective of this study is to assess health related quality of life of HIV/AIDS patients attending ART clinic Tertiary care hospital, GGH, Kurnool and to determine the association of socio-demographic and disease related variables with health related quality of life.Methods: A cross-sectional study was conducted from April 2019 to June 2019 involving 400 purposively selected HIV-positive patients of age >18 years, who were taking highly active anti-retroviral therapy for the past 6months from the ART center, GGH, Kurnool. After obtaining IEC clearance and informed consent, WHOQOL-BREF instrument was used for data collection. Data analysis was performed using IBM SPSS version 26.0.Results: Out of the 400 participants, 60% were males. The mean age of the participants was 38.5±10.54 years. Overall quality of life had a mean score of 69.71. Physical (82.57) and level of independence (78.78) domains showed higher mean score when compared to psychological (63.82), environmental (61.49) and Social (60.26) domains.Conclusions: Among study subjects 15.5% had excellent QoL (≥80), nearly 69.75% had good QoL (60-79) and 14.75% had poor QoL (<60). Low QoL scores were seen in the social domain, suggesting that more social interventions are required in this population.


Author(s):  
Atul Agrawal ◽  
Ankita Agrawal

Background: Human Immunodeficiency Virus (HIV) has become one of the most serious challenges to public health due to its high morbidity, mortality and economic impacts. Good Knowledge, positive attitudes and practices are important aspects of providing nursing care for people living with HIV/AIDS. Aim: This study aimed to assess knowledge, attitudes and practices of nurses working with HIV/AIDS patients. Methods: This study was descriptive, performed on 200 nurses working with HIV/AIDS patients at a tertiary care Hospital, Amroha. Data was collected using pretested, validated, self administered questionnaire consisting of knowledge, attitude and practice based questions related to HIV/Aids and infected patients along with demographic variables of nursing staff under study.  Results: The result of this study showed that majority of nurses (81%) working with HIV/AIDS patients possess adequate level of knowledge. Most of the nurses under study showed high level of empathic attitude toward people living with HIV/AIDS (above 80%) but at the same time high level of avoidance was observed among some nurses. Practice of nurses working with HIV/AIDS patients was found good. Conclusions: There was satisfactory knowledge, positive attitudes and good practice level among nurses under study. Recommendations: Training should focus on Preventive methods and modes of HIV transmission, care and support of all patients no matter what the disease, emphasizing confidentiality as a patient right that should not be ignored and should train nurses and monitor nursing skills. Keywords: Public health, Nurses, HIV, Knowledge, Attitude, Practices


Author(s):  
Srishti Dixit ◽  
Nirmal Verma ◽  
Neha Shrivastava ◽  
Mini Sharma ◽  
Somen Kumar Pradhan ◽  
...  

Background: ART centres provide the comprehensive care to the people living with HIV (PLHIV) in public sector. Patients’ satisfaction is one of the commonly used outcome measures of patient care. The objective was to assess the level of satisfaction of PLHIV and factors associated with PLHIV satisfaction with the services at ART centre.Methods: The study was a cross-sectional design carried out at a tertiary level health care centre, Raipur during March 2016 to May 2016. A total of 320 PLHIV were selected into the study using systematic sampling. A pre-designed, pre-tested questionnaire was used to obtain data from the participants.Results: The mean age of the PLHIV was 37.76 years±8.59. The highest score was in “satisfaction with interaction with the pharmacist” (15.38±2.786), and the lowest in “satisfaction with general services” (13.67±2.822). 61.3% of all 320 respondents were satisfied with the overall services provided at ART centre. Older, less educated, those who take lesser time to reach ART centre and adherent respondents were more likely to be satisfied with the services.Conclusions: The study shows generally high satisfaction with services but there is still need for improvement of services in some areas where the patients showed dissatisfaction.


2020 ◽  
Vol 9 (11) ◽  
pp. 5646
Author(s):  
SoumyaS Sahoo ◽  
Pardeep Khanna ◽  
Ramesh Verma ◽  
Madhur Verma ◽  
Sandeep Mahapatra ◽  
...  

Author(s):  
Akanksha Singh ◽  
Deepak Chopra ◽  
Sarver Jahan ◽  
Razia Khatoon

Background: HIV (Human Immunodeficiency Virus) is the causative agent of AIDS (Acquired Immunodeficiency Syndrome). It belongs to the lentivirus subgroup of the family Retroviridae. The HIV/AIDS is spreading worldwide at an alarming rate. India has the third largest number of estimated people living with HIV/AIDS. Most common mode of HIV transmission is through heterosexual contact, blood transfusion, percutaneous, mucosal and perinatal mode. The present study was done to evaluate the seroreactivity of HIV among patients attending Integrated Counselling and Testing Centre (ICTC) of our Tertiary care hospital.  Methods: This retrospective study was conducted on data of patients who had attended ICTC and undergone HIV testing from January 2017 to January 2019. A total of 4519 patients were included in the study who gave their consent followed by pre-test and post-test counseling and were screened for HIV antibody by using rapid kit Comb-Aids.Results: Out of 4519 samples tested, 23 were reactive to HIV screening test, hence sero-reactivity of HIV was found to be 0.50%. Higher seroreactivity was seen among males (56.5%, 13/23), and patients aged 31-40 years (39.1%, 9/23). Maximum seroreactivity was found among patients of rural areas (73.9%, 17/23), indoor patients (91.3%, 21/23) and married patients (73.9%, 17/23).Conclusions: In this study the seroreactivity of HIV was found to be low among patients attending ICTC but still HIV continues to be a major contributor to the global burden of disease. ICTC data can be used as an important tool for planning and improving the national HIV/AIDS intervention strategy.


2010 ◽  
Vol 40 (2) ◽  
pp. 81-84 ◽  
Author(s):  
Mirta Garcia-Jardon ◽  
Vivek G Bhat ◽  
E Blanco-Blanco ◽  
Andrez Stepian

South Africa has the largest number of people living with HIV/AIDS, and various associated infectious and noninfectious conditions contribute towards mortality. The objective of this study was to determine the important post-mortem findings in HIV-infected individuals in a high HIV burden rural area in South Africa. The patient population included HIV patients who died at the tertiary care hospital, from 2000–2008. Autopsies were performed according to standard protocols and diagnoses were made with additional laboratory investigations wherever required. A total of 86 patients were autopsied (30 males, 56 females). The major postmortem findings were related to infections, with 38% of the patients having had some form of tuberculosis, followed by pyogenic infections – pneumonias (21.5%), meningitis (10.1%) and septicemias (5.1%). Other important infections included opportunistic fungi like cryptococcosis (7.6%) and pneumocystis pneumonia (8.9%). Among the noninfectious conditions, the findings seen were predominantly related to liver (10.1%) and cardiac involvement (10.1%).


Author(s):  
Rushali Rajan Lilare ◽  
Uday Wasudeorao Narlawar ◽  
Ganpat Mirdude

Background: The present study was retrospective record based, conducted with the aim of assessing the functional status and CD4 count of patients living with HIV/AIDS attending the ART Centre in special reference to gender difference at tertiary care hospital of central India.Methods: Study subjects were people living with HIV/AIDS registered at ART centre at tertiary care hospital of central India in the past three years (1 Jan. 2011 to 31 Dec. 2013). The study duration was from September 2013 to January 2015. This study was conducted on 2042 PLHIV subjects whose records were available for study.Results: In our study there were 58.37% males, 42.4% female and 0.15% transgender. Majority of male 42.45% were between 35-44 years of age group whereas 36.95% females were between 25-34years of age group. Majority of males 22.16% were non agricultural labourer whereas females 78.32% were homemaker. Majority of males 37.41% were in the WHO clinical stage 3 whereas majority of females 36.70% were in stage 1 at the start of ART treatment. About 84.30% females and 76.9% male were working at the start of ART. Majority of males 31.12% and 38.79% had CD4 count between 51-150 at the time of ART registration and at the time of ART treatment respectively. Majority of males 42.62% and 29.34% had CD4 count >350 and between151-250 respectively. About 16.53 % males and 8.97% female were died at the time of data collection.Conclusions: In the study there were male preponderance with 75.26% males and 57.39% females were having CD4 count less than350/cumm at the time of registration respectively. Majority of our study subjects were working at the time of start of ART. The deaths among males were significantly more as compared to females.


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