scholarly journals Migraine Disability, Pain Catastrophizing, And Headache Severity Are Associated With Evoked Pain And Targeted By Mind-Body Therapy

Author(s):  
Samuel R Krimmel ◽  
Michael L Keaser ◽  
Darrah R Speis ◽  
Jennifer A Haythornthwaite ◽  
David A Seminowicz

Meta-analysis suggests migraine patients are no more sensitive to experimentally evoked pain than healthy controls. At the same time, studies have linked some migraine symptoms to Quantitative Sensory Testing (QST) profiles. Unfortunately, previous studies associating migraine symptoms and QST have important methodological shortcomings, stemming from inappropriate statistics, small sample sizes, and frequent use of univariate statistics for multivariate research questions. In the current study we seek to address these limitations by using a large sample of episodic migraine patients (n=103) and a multivariate analysis that associates pain ratings from many thermal intensities simultaneously with 12 clinical measures ranging from headache frequency to sleep abnormalities. We identified a single dimension of association between QST and migraine symptoms that relates to pain ratings for all stimulus intensities and a subset of migraine symptoms relating to disability (Headache Impact Trauma 6 and Brief Pain Inventory interference), catastrophizing (Pain Catastrophizing Scale), and pain severity (average headache pain, Brief Pain Inventory severity, and Short Form McGill Pain Questionnaire 2). Headache frequency, allodynia, affect, and sleep disturbances were unrelated to this dimension. Consistent with previous research, we did not observe any difference in QST ratings between migraine patients and healthy controls. Additionally, we found that the linear combination of symptoms that related to QST were modified by mind-body therapy. These results suggest that QST has a selective relationship with pain symptoms even in the absence of between-subjects differences between chronic pain patients and healthy controls.

2020 ◽  
Author(s):  
Qinxue Shen ◽  
Ting Guo ◽  
Min Song ◽  
Wei Guo ◽  
Yi Zhang ◽  
...  

Abstract Background Less is known about the prevalence and characteristics of pain in interstitial lung disease (ILD) patients.To determine the characteristics of pain in ILD patients. Methods Participants with ILD and age, gender-matched, healthy controls completed short form McGill Pain Questionnaire (SF-MPQ) and part of the Brief Pain Inventory short form(BPI) to elicit pain characteristics. ILD patients also had assessments of pulmonary function test, six minutes walking test (6MWT), modified medical research council dyspnea scale (mMRC) for state of the illness and measured health-related quality of life(HRQoL) by short form-36(SF-36)and psychological associations by hospital anxiety and depression scale(HADS). Results A total of 63 participants with ILD and 63 healthy controls(HC) were recruited in our study. The prevalence of pain was 61.9% in ILDs versus 25.3% in HC (p=0.005) and the median score of pain rank index (PRI) in ILDs was higher than in HC (P=0.014). Chest(46.1%) accounted for the highest of overall pain locations in participants with ILD. Associated clinical factors for pain intensity in ILD patients included younger age (<60 years), exposure history of ILD risk factors, longer distance of 6MWD(≥250m), higher mMRC score(2-4) and lower DLCo, % predicted(≤45%). ILD patients with pain are more likely to suffer impaired HRQoL(P=0.0014) and psychological problems(P=0.0017,P=0.044). Conclusion Pain is common in those with ILD and the pain intensity is associated with age, exposure history, 6MWD, mMRC score and DLCo, % predicted. ILD patients with pain have more possible to suffer depression, anxiety and impaired HRQoL.


2020 ◽  
Author(s):  
Qinxue Shen ◽  
Ting Guo ◽  
Min Song ◽  
Wei Guo ◽  
Yi Zhang ◽  
...  

Abstract Background Less is known about the prevalence and characteristics of pain in interstitial lung disease (ILD) patients. To determine the characteristics of pain in ILD patients.Methods Participants with ILD and age, gender-matched, healthy controls completed short form McGill Pain Questionnaire (SF-MPQ) and part of the Brief Pain Inventory short form(BPI) to elicit pain characteristics. ILD patients also had assessments of pulmonary function test, six minutes walking test (6MWT), modified medical research council dyspnea scale (mMRC) for state of the illness and measured health-related quality of life(HRQoL) by short form-36(SF-36)and psychological associations by hospital anxiety and depression scale(HADS).Results A total of 63 participants with ILD and 63 healthy controls(HC) were recruited in our study. The prevalence of pain was 61.9% in ILDs versus 25.3% in HC (p = 0.005) and the median score of pain rank index (PRI) in ILDs was higher than in HC (P = 0.014). Chest(46.1%) accounted for the highest of overall pain locations in participants with ILD. Associated clinical factors for pain intensity in ILD patients included younger age (< 60 years), exposure history of ILD risk factors, longer distance of 6MWD(≥ 250 m), higher mMRC score(2–4) and lower DLCo, % predicted(≤ 45%). ILD patients with pain are more likely to suffer impaired HRQoL(P = 0.0014) and psychological problems(P = 0.0017,P = 0.044).Conclusion Pain is common in those with ILD and the pain intensity is associated with age, exposure history, 6MWD, mMRC score and DLCo, % predicted. ILD patients with pain have more possible to suffer depression, anxiety and impaired HRQoL.


F1000Research ◽  
2013 ◽  
Vol 2 ◽  
pp. 164 ◽  
Author(s):  
Rebecca Fisher ◽  
Judith Ewing ◽  
Alice Garrett ◽  
E Katherine Harrison ◽  
Kimberly KT Lwin ◽  
...  

Background: Homeless people are known to suffer disproportionately with health problems that reduce physical functioning and quality of life, and shorten life expectancy. They suffer from a wide range of diseases that are known to be painful, but little information is available about the nature and prevalence of chronic pain in this vulnerable group. This study aimed to estimate the prevalence of chronic pain among homeless people, and to examine its location, effect on activities of daily living, and relationship with alcohol and drugs.Methods: We conducted face-to-face interviews with users of homeless shelters in four major cities in the United Kingdom, in the winters of 2009-11. Participants completed the Brief Pain Inventory, Short Form McGill Pain questionnaire, Leeds Assessment of Neuropathic Symptoms and Signs, and detailed their intake of prescribed and unprescribed medications and alcohol. We also recorded each participant’s reasons for homelessness, and whether they slept rough or in shelters.Findings: Of 168 shelter users approached, 150 (89.3%) participated: 93 participants (63%) reported experiencing pain lasting longer than three months; the mean duration of pain experienced was 82.2 months. The lower limbs were most frequently affected. Opioids appeared to afford a degree of analgesia for some, but whilst many reported symptoms suggestive of neuropathic pain, very few were taking anti-neuropathic drugs.Interpretation: The prevalence of chronic pain in the homeless appears to be substantially higher than the general population, is poorly controlled, and adversely affects general activity, walking and sleeping. It is hard to discern whether chronic pain is a cause or effect of homelessness, or both. Pain is a symptom, but in this challenging group it might not always be possible to treat the underlying cause. Exploring the diagnosis and treatment of neuropathic pain may offer a means of improving the quality of these vulnerable people’s lives.


Cephalalgia ◽  
2009 ◽  
Vol 30 (5) ◽  
pp. 560-566 ◽  
Author(s):  
PAS Rocha-Filho ◽  
JLD Gherpelli ◽  
JTT de Siqueira ◽  
GD Rabello

Seventy-nine patients with intracranial aneurysms were evaluated in the presurgical period, and followed up to 6 months after surgery. We compare patients who fulfilled with those that did not post-craniotomy headache (PCH) diagnostic criteria, according to the International Classification of Headache Disorders. Semistructured interviews, headache diaries, Short Form-36 and McGill Pain Questionnaire were used. Seventy-two patients (91%) had headaches during the follow-up period. The incidence of PCH according to the International Headache Society diagnostic criteria was 40%. Age, sex, type of surgery, temporomandibular disorder, vasospasm, presence and type of previous headaches, and subarachnoid haemorrhage were not related to headache classification. There were no differences in the quality of life, headache frequency and characteristics or pain intensity between patients with headache that fulfilled or not PCH criteria. We proposed a revision of the diagnostic criteria for PCH, extending the headache outset after surgery from 7 to 30 days, and including the presence of headaches after surgery in patients with no past history of headaches, or an increase in headache frequency during the first 30 days of the postsurgical period followed by a decrease over time. Using these criteria we would classify 65% of our patients as having PCH.


2020 ◽  
Author(s):  
Qinxue Shen ◽  
Ting Guo ◽  
Min Song ◽  
Wei Guo ◽  
Yi Zhang ◽  
...  

Abstract Background: As it is less known about the prevalence and characteristics of pain in the patients with interstitial lung disease (ILD), this paper aims at determining the characteristics of the pain in the patients with ILD.Methods: Subjects with ILD and health controls with the matched ages and genders completed Short Form McGill Pain Questionnaire (SF-MPQ) and part of the Brief Pain Inventory (BPI) Short Form to elicit the characteristics of the pain. The patients with ILD were also assessed through Pulmonary Function Test, Six Minutes Walking Test (6MWT), modified Medical Research Council Dyspnea Scale (mMRC) for state of the illness and measured health-related quality of life (HRQoL) by Short Form-36 (SF-36) and psychological associations by Hospital Anxiety and Depression Scale (HADS).Results: A total of 63 subjects with ILD and 63 healthy controls (HC) were recruited in our study. The prevalence of the pain was 61.9% in ILD versus 25.3% in HC (p=0.005) and the median score of the pain rank index (PRI) in ILD was higher than that in HC (P=0.014). Chest (46.1%) accounted for the highest of overall pain locations in subjects with ILD. Associated clinical factors for pain intensity in the patients with ILD included exposure history of risk factors of ILD, with a longer distance of 6MWD (≥250m), and a higher mMRC score (2-4). The patients with ILD and pain are more likely to suffer impaired HRQoL (P=0.0014) and psychological problems (P=0.0017, P=0.044).Conclusion: The pain is common in those with ILD and the pain intensity is associated with exposure history, 6MWD, and mMRC score. The patients with ILD and pain were possibly to suffer depression, anxiety, and impaired HRQoL.


2017 ◽  
Vol 41 (S1) ◽  
pp. S522-S522
Author(s):  
B. Batinic ◽  
J. Nesvanulica ◽  
I. Stankovic

IntroductionStudies have shown that somatic pain influences the severity of major depressive disorder (MDD), and could be moderated through pain coping strategies and not catastrophizing to pain.ObjectivesThe aim of the study was to ascertain the correlation between pain coping strategies, catastrophizing to pain and severity of depression.MethodsThe study sample consisted of 82 patients diagnosed with MDD, aged between 18 and 65 years old (M = 46.21). Assessment instruments included The Beck Depression Inventory-II (BDI-II), The Brief Pain Inventory-Short Form-BPISF (consisting of two subscales: BPI1-intensity of pain, and BPI2-interference with daily functioning), The Vanderbilt Pain Management Inventory-VPMI (consisting of active-VPMIAC and passive pain coping mechanism subscales-VPMIPC) and The Pain Catastrophizing Scale-PCS (consisting of subscales of rumination, exaggeration and helplessness).ResultsThe average BDI-II score was 27.21 (SD = 11.53); the average score at BPI1 was 2.99 (SD = 2.83) and 3.35 (SD = 3.26) at BPI2; the average scores on the active coping mechanism subscale was 20.72 (SD = 4.87), and on the passive coping mechanism subscale 34.05 (SD = 7.86); the average catastrophizing scale score was 28.78 (SD = 10.72). Active mechanism of pain coping has shown significant negative correlation with depression (r = –0.227, P > 0.05) while passive mechanism of pain coping has shown significant positive correlation with depression (r = 0.269, P > 0.05). Intensity of depression was significantly positively correlated with intensity of catastrophizing to pain (r = 0.358, P > 0.01) and its derivatives: rumination, exaggeration and helplessness.ConclusionInterventions focusing on targeting catastrophizing to pain and pain coping mechanisms should be considered in the treatment of patients with MDD with somatic pain.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2011 ◽  
Vol 14 (1) ◽  
pp. 366-373 ◽  
Author(s):  
Ana I. Sánchez ◽  
M. Pilar Martínez ◽  
Elena Miró ◽  
Ana Medina

Objective: This study analyzes the role of a number of cognitive-affective dimensions in the experience and coping of pain in patients with fibromyalgia (FM). Specifically, it was examined whether anxiety, depression, pain catastrophizing and pain-related anxiety predict the pain perception and the self-efficacy expectations in these patients.Method: Seventy-four fibromyalgia patients were asked to complete a questionnaire survey including theChronic Pain Self-Efficacy Scale, theHospital Anxiety and Depression Scale, thePain Anxiety Symptoms Scale-20, thePain Catastrophizing Scale, and theShort-form McGill Pain Questionnaire. Results: Some relevant correlation and predicting patterns were identified. Physiological anxiety was the best predictor of the sensorial dimension of pain. Pain fear was a significant predictor of the pain intensity. Helplessness was the best predictor of the affective dimension of pain, whereas depression was a significant predicting variable of the self-efficacy expectations.Conclusions: This study shows the relevance of the pain-related anxiety in the pain perception, and of the depression in the self-efficacy expectations in FM patients. Clinical applications of the findings and further research lines in this area are discussed.


2008 ◽  
Vol 13 (4) ◽  
pp. 299-308 ◽  
Author(s):  
Megan A Davidson ◽  
Dean A Tripp ◽  
Leandre R Fabrigar ◽  
Paul R Davidson

BACKGROUND: There are many measures assessing related dimensions of the chronic pain experience (eg, pain severity, pain coping, depression, activity level), but the relationships among them have not been systematically established.OBJECTIVE: The present study set out to determine the core dimensions requiring assessment in individuals with chronic pain.METHODS: Individuals with chronic pain (n=126) completed the Beck Anxiety Inventory, Beck Depression Inventory, Beck Hopelessness Scale, Chronic Pain Coping Index, Multidimensional Pain Inventory, Pain Catastrophizing Scale, McGill Pain Questionnaire – Short Form, Pain Disability Index and the Tampa Scale of Kinesiophobia.RESULTS: Before an exploratory factor analysis (EFA) of the nine chronic pain measures, EFAs were conducted on each of the individual measures, and the derived factors (subscales) from each measure were submitted together for a single EFA. A seven-factor model best fit the data, representing the core factors of pain and disability, pain description, affective distress, support, positive coping strategies, negative coping strategies and activity.CONCLUSIONS: Seven meaningful dimensions of the pain experience were reliably and systematically extracted. Implications and future directions for this work are discussed.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Seonghoon Kim ◽  
Dae-Woong Bae ◽  
Sang-Gue Park ◽  
Jeong-Wook Park

AbstractThe response to pain is highly individual and can be influenced by complex emotional perception. This study aims to investigate the status of the pain-related emotional response, and the influence on headache characteristics and disability in migraine. We studied the pain-related emotional response in 145 consecutive migraine patients using the Pain Anxiety Symptoms Scale (PASS), the Pain Catastrophizing Scale (PCS), and the Pain Sensitivity Questionnaire (PSQ) and compared them with 106 healthy controls. We investigated the relationship between emotional factors and migraine characteristics. The effect of pain-related emotion on migraine-related disability assessed with the Headache Impact Test-6 (HIT-6) and the Migraine Disability Assessment (MIDAS). Migraine patients showed significantly higher scores on total PASS (p < 0.001), PCS (p < 0.001) and PSQ (p = 0.002) compared to the healthy controls. The HIT-6 was weakly correlated with PASS (r = 0.390, p < 0.001) and PCS (r = 0.354, p < 0.001). PASS-Total (p = 0.001), headache frequency (p = 0.003), and HADS-Anxiety (p = 0.028) were independent variables associated with HIT-6. Headache frequency (p < 0.001) was an independent variable associated with MIDAS. The structural equation model indicated that headache severity has direct loading on emotion and subsequently influenced migraine-related disability. Disability has a significant effect on the frequency of abortive medication use. Migraine patients have altered emotional responses to pain perception. Pain-related anxiety made an important contribution to headache-related disability. The present results suggest that the management of disability by considering various pain-related emotional factors may be necessary for the therapeutic aspects of migraine.


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