scholarly journals Preventing co-infection: a viral strategy with short-term benefits and long-term drawbacks

2021 ◽  
Author(s):  
Michael Hunter ◽  
Diana Fusco
Keyword(s):  
Growth Rate ◽  
Life History ◽  
Negative Impact ◽  
Viral Evolution ◽  
Viral Fitness ◽  
Viral Population ◽  
Short Term ◽  
Life History Parameters ◽  
Wide Range

ABSTRACTViral co-infection occurs when multiple distinct viral particles infect the same host. This can impact viral evolution through intracellular interactions, complementation, reassortment and recombination. In nature many viral species are found to have a wide range of mechanisms to prevent co-infection, which raises the question of how viral evolution is impacted by this strategic choice. Here, we address this question in a model viral system, the ubiquitous bacteriophage and its host bacteria. Using a stochastic model of phage-host interactions in agent-based simulations, we first characterise the behaviour of neutral mutants and find that co-infection decreases the strength of genetic drift. We then quantify how variations in the phage life history parameters affect viral fitness. Importantly, we find that the growth rate (dis)advantage associated with variations in life history parameters can be dramatically different from the competitive (dis)advantage measured in direct-competition simulations. Additionally, we find that co-infection facilitates the fixation of beneficial mutations and the removal of deleterious ones, suggesting that selection is more efficient in co-infecting populations. We also observe, however, that in populations which allow co-infection, a mutant that prevents it displays a substantial competitive advantage over the rest of the population, and will eventually fix even if it displays a much lower growth rate in isolation. Our findings suggest that while preventing co-infection can have a negative impact on the long-term evolution of a viral population, in the short-term it is ultimately a winning strategy, possibly explaining the prevalence of phage capable of preventing co-infection in nature.

scholarly journals Analiza potencjalnych korzyści oraz negatywnych konsekwencji wdrożenia norm LCR oraz NSFR w bankach europejskich

2015 ◽  
Vol 1 (3) ◽  
pp. 207-226
Author(s):  
Paweł Niedziółka
Keyword(s):  
Growth Rate ◽  
Banking Sector ◽  
Negative Impact ◽  
Balance Sheet ◽  
Short Term ◽  
The Real ◽  
Structure Changes ◽  
Sheet Structure ◽  
The Cost

The introduction of liquidity ratios on the banking sector and the real economywill lead to adaptation of the banks. Mismatch between the maturity of assets andliabilities will be subject to reduction. These shifts in the banks’ balance sheetsmay result in diminishing profitability of banks as long as the cost of maintainingadditional capital and balance sheet structure changes will not be passed on to customers. Another consequence may be an impediment to access of nonfinancialentities to long-term financing. Thus, increased cost of credit and reductionof its availability in the short term will have negative impact on economicgrowth while introduction of liquidity standards and new capital requirementssignificantly reduces the probability of a banking crisis, which compensates forinterim and slight decrease in the growth rate.

scholarly journals The interplay of gender, social context, and long-term unemployment effects on subjective health trajectories

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Laura Altweck ◽  
Stefanie Hahm ◽  
Holger Muehlan ◽  
Tobias Gfesser ◽  
Christine Ulke ◽  
...  
Keyword(s):  
Life Satisfaction ◽  
Social Context ◽  
Negative Impact ◽  
Subjective Health ◽  
Short Term ◽  
Self Rated Health ◽  
Health Trajectories ◽  
Lower Baseline ◽  
Baseline Values

Abstract Background While a strong negative impact of unemployment on health has been established, the present research examined the lesser studied interplay of gender, social context and job loss on health trajectories. Methods Data from the German Socio-Economic Panel was used, which provided a representative sample of 6838 participants. Using latent growth modelling the effects of gender, social context (East vs. West Germans), unemployment (none, short-term or long-term), and their interactions were examined on health (single item measures of self-rated health and life satisfaction respectively). Results Social context in general significantly predicted the trajectories of self-rated health and life satisfaction. Most notably, data analysis revealed that West German women reported significantly lower baseline values of self-rated health following unemployment and did not recover to the levels of their East German counterparts. Only long-term, not short-term unemployment was related to lower baseline values of self-rated health, whereas, in relation to baseline values of life satisfaction, both types of unemployment had a similar negative effect. Conclusions In an economic crisis, individuals who already carry a higher burden, and not only those most directly affected economically, may show the greatest health effects.

ON THE CONSUMPTION/DISTRIBUTION THEOREM UNDER THE LONG-RUN GROWTH CRITERION SUBJECT TO A DRAWDOWN CONSTRAINT

2010 ◽  
Vol 13 (06) ◽  
pp. 931-957 ◽  
Author(s):  
MICHAEL J. KLASS ◽  
KRZYSZTOF NOWICKI
Keyword(s):  
Growth Rate ◽  
Short Term ◽  
Long Run ◽  
Time Period ◽  
Total Capital ◽  
Growth Criterion ◽  
Drawdown Constraint ◽  
Riskless Asset ◽  
Distribution Theorem

Consider any discrete time sequence of investment fortunes Fn which has a finite long-run growth rate [Formula: see text] when subject to the present value capital drawdown constraint Fne-rn ≥ λ* max 0≤k≤nFke-rk, where 0 ≤ λ* < 1, in the presence of a riskless asset affording a return of er dollars per time period per dollar invested. We show that money can be withdrawn for consumption from the invested capital without either reducing the long-run growth rate of such capital or violating the drawdown constraint for our capital sequence, while simultaneously increasing the amount of capital withdrawn for consumption at the identical long-term rate of V(r, λ*). We extend this result to an exponentially increasing number of consumption categories and discuss how additional yearly contributions can temporarily augment the total capital under management. In addition, we assess the short-term practicality of creating such an endowment/consumption/distribution program.

العلاقة التبادلية بين سعر الصرف وأسعار الأسهم دراسة تطبيقية في سوق اسطنبول للأوراق المالية للمدة 2005-2020

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
سعدالله ألنعيمي
Keyword(s):  
Exchange Rate ◽  
Stock Prices ◽  
Negative Impact ◽  
Reciprocal Relationship ◽  
Nominal Exchange Rate ◽  
Share Price ◽  
Theoretical Interpretation ◽  
Short Term ◽  
The Exchange Rate

The study aims to analyzing the reciprocal relationship between the nominal exchange rate of the Turkish lira versus the U.S. dollar and the stock prices of the companies listed on the Istanbul Stock Exchange (ISE) expressed in the general market index for the period from 2005 to 2020 with 192 monthly observations, based on the traditional theory and the theory of portfolio balance model in theoretical interpretation for that relationship, aiming to identify the effect of the exchange rate on stock prices, as well as to analyze the causal relationship between those variables and to identify which of them is the cause or which is the result, using the Autoregressive Distributed Lag (ARDL) model. The research found that the exchange rate has a positive effect on stock prices in the long term, despite the emergence of the negative impact in the short term, but the long-term relationship has corrected the course of the short-term relationship with a time period not exceeding one month, in addition to proving that this relationship takes one direction. From the exchange rate towards stock prices, that is, the exchange rate is the reason and stock prices are the result, therefore the results of this research helps investors to predict future trends of stock prices depending on the exchange rate changes, and it also enables the companies, especially those with foreign transactions, to manage price risks the exchange rate in order to avoid its negative impact on its share price, as it represents an obstacle to achieving its main goal of maximizing the share price

scholarly journals PSIKOEDUKASI MENGENAI DAMPAK BULLYING DAN CARA MENINGKATKAN SELF-ESTEEM PADA REMAJA

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Grace Amin
Keyword(s):  
Young People ◽  
Negative Impact ◽  
Self Esteem ◽  
Religious Communities ◽  
Short Term ◽  
Aggressive Action ◽  
Effects Of Bullying ◽  
Anxiety Depression ◽  
The Impact

Bullying is deliberate aggressive action, using an imbalance of strength physically or mentally by hurting physical, verbal, or emotional / psychological forms repeatedly. In the last decade, cases of bullying in Indonesia continue to increase and if not handled properly will increasingly have a negative impact on the development of the children of the nation's next generation. Bullying does not only affect children who are bullied but can also affect children who bully, children who witness bullying. Some of the effects of bullying include anxiety, depression, and low self-esteem. The purpose of community engagement is to socialize the impact of bullying and how to increase self-esteem to adolescents. Through psychoeducation programs in adolescents such as schools and teenagers religious communities in the Cikarang - Bekasi region, young people gain an in-depth understanding of bullying, its effects and how to increase their confidence. Through this psychoeducation, teenagers understand the understanding, types and effects of bullying both short term and long term so they promise to resist bullying starting from themselves. Teenagers learn that humans are social beings who need each other. They learn about the meaning of diversity and bhineka tunggal ika and try to implement it in their next lives by respecting the differences in their environment. These teenagers learn to respect themselves more, see the positive things that God has given them. They try to always believe in themselves that they are perfect and valuable beings in God's eyes so that even though the environment around them may not appreciate, they can still see positive things in themselvesABSTRAK:Bullying adalah tindakan agresif yang disengaja, menggunakan ketidakseimbangan kekuatan secara fisik atau mental dengan cara menyakiti bentuk fisik, verbal, atau emosional/ psikologis secara berulang – ulang. Dalam satu decade terakhir, kasus bullying di Indonesia terus meningkat dan bila tidak ditangani dengan baik akan semakin berdampak negative bagi perkembangan anak – anak generasi penerus bangsa. Tindakan bullying tidak hanya berdampak pada anak yang di-bully tetapi juga dapat berdampak pada anak yang mem-bully, anak yang menyaksikan bullying. Beberapa dampak bullying diantaranya kecemasan, depresi, serta rendahnya harga diri (self-esteem). Tujuan dari pengabdian kepada masyarakat ini adalah untuk mensosialisasikan dampak bullying serta cara meningkatkan self-esteem kepada para remaja. Melalui program psikoedukasi di lingkungan remaja seperti sekolah maupun komunitas keagamaan remaja wilayah Cikarang – Bekasi, para remaja mendapatkan pemahaman mendalam mengenai bullying, dampaknya serta bagaimana cara meningkatkan kepercayaan diri mereka. Melalui psikoedukasi ini, para remaja memahami pengertian, jenis serta dampak bullying baik jangka pendek maupun jangka panjang sehingga mereka berjanji untuk bersikap menolak bullying mulai dari diri mereka sendiri. Para remaja belajar bahwa manusia adalah mahluk social yang saling membutuhkan. Mereka belajar tentang makna keberagaman dan Bhineka Tunggal Ika serta berusaha mengimplementasikannya dalam kehidupan mereka selanjutnya dengan cara menghargai perbedaan yang ada di lingkungannya. Remaja ini belajar untuk lebih menghargai diri mereka, melihat hal positif yang telah diberikan Tuhan kepada mereka. Mereka mencoba untuk selalu menanamkan dalam diri bahwa mereka adalah mahluk yang sempurna dan berharga di mata Tuhan sehingga walaupun lingkungan di sekitar mereka mungkin tidak menghargai, mereka tetap dapat melihat hal positif dalam diri mereka.

scholarly journals Perception of investing in crypto in India using UTAUT model

2021 ◽  
Vol 9 (10) ◽  
pp. 1396-1400
Author(s):  
Vidhi Shah
Keyword(s):  
Indian Population ◽  
Social Benefits ◽  
Short Term ◽  
Perceived Safety ◽  
Utaut Model ◽  
Performance Expectancy ◽  
Wide Range ◽  
Effort Expectancy ◽  
Do So

Abstract: This research was conducted to gather data and understand the perception what the Indian population holds when it comes to investing in cryptocurrency. To do so, a survey was designed using the UTAUT model and was circulated by the means of google forms. A wide range of parameters were considered to avail the maximum possible accuracy for the data collected. Parameters like, the ease of investing crypto, short term and long term benefits, monetary benefits, social benefits were considered. All of these parameters were supposed to be answered on a scale of 5. After collecting all the data, the results were analyzed and evaluated using which the hypothesis made were proved. Keywords: Cryptocurrency, UTAUT, performance expectancy, effort expectancy, perceived monetary benefits, perceived safety, social influence, adoption intension.

scholarly journals Will the COVID-19 pandemic lead to a tsunami of suicides? A Swedish nationwide analysis of historical and 2020 data

2020 ◽  
Author(s):  
Christian Rück ◽  
David Mataix-Cols ◽  
Kinda Malki ◽  
Mats Adler ◽  
Oskar Flygare ◽  
...  
Keyword(s):  
Negative Impact ◽  
Annual Data ◽  
Short Term ◽  
Death Rates ◽  
Men And Women ◽  
Influenza Pandemics ◽  
Suicide Rates ◽  
Distributed Lag ◽  
The Media

ABSTRACTBackgroundVarious surveys have documented a negative impact of the COVID-19 pandemic on the population’s mental health. There is widespread concern about a surge of suicides, but evidence supporting a link between global pandemics and suicide is very limited. Using historical data from the three major influenza pandemics of the 20th century, and recently released data from the first half of 2020, we aimed to investigate whether an association exists between influenza deaths and suicide deaths.MethodsAnnual data on influenza death rates and suicide rates were extracted from the Statistical Yearbook of Sweden from 1910-1978, covering the three 20th century pandemics, and from Statistics Sweden for the period from January to June of each year during 2000-2020. COVID-19 death data were available for the first half of 2020. We implemented non-linear autoregressive distributed lag (NARDL) models to explore if there is a short-term and/or long-term effect of increases and decreases in influenza death rates on suicide rates during 1910-1978. Analyses were done separately for men and women. Descriptive analyses were used for the available 2020 data.FindingsBetween 1910-1978, there was no evidence of either short-term or long-term significant associations between influenza death rates and changes in suicides. The same pattern emerged in separate analyses for men and women. Suicide rates in January-June 2020 revealed a slight decrease compared to the corresponding rates in January-June 2019 (relative decrease by −1.2% among men and −12.8% among women).InterpretationWe found no evidence of short or long-term association between influenza death rates and suicide death rates across three 20th century pandemics or during the first six months of 2020 (when the first wave of COVID-19 occurred). Concerns about a substantial increase of suicides may be exaggerated. The media should be cautious when reporting news about suicides during the current pandemic.

scholarly journals Observations of rapid-fire event tremor at Lascar volcano, Chile

1996 ◽  
Vol 39 (2) ◽  
Author(s):  
G. Asch ◽  
K. Wylegalla ◽  
M. Hellweg ◽  
D. Seidl ◽  
H. Rademacher
Keyword(s):  
Fractal Structure ◽  
Seismic Station ◽  
Active Volcano ◽  
Short Term ◽  
Fire Event ◽  
Local Seismicity ◽  
Short Period ◽  
Wide Range ◽  
Lascar Volcano

During the Proyecto de Investigaciòn Sismològica de la Cordillera Occidental (PISCO '94) in the Atacama desert of Northern Chile, a continuously recording broadband seismic station was installed to the NW of the currently active volcano, Lascar. For the month of April, 1994, an additional network of three, short period, three-component stations was deployed around the volcano to help discriminate its seismic signals from other local seismicity. During the deployment, the volcanic activity at Lascar appeared to be limited mainly to the emission of steam and SO2. Tremor from Lascar is a random, «rapid-fire» series of events with a wide range of amplitudes and a quasi-fractal structure. The tremor is generated by an ensemble of independent elementary sources clustered in the volcanic edifice. In the short-term, the excitation of the sources fluctuates strongly, while the long-term power spectrum is very stationary.

scholarly journals Prospects for Vietnam’s Economy in 2013

2013 ◽  
Vol 215 ◽  
pp. 02-11
Author(s):  
NGÂN TRẦN HOÀNG
Keyword(s):  
Economic Growth ◽  
Growth Rate ◽  
World Economy ◽  
Inflation Rate ◽  
Economic Restructuring ◽  
Short Term ◽  
Economic Growth Model ◽  
The World ◽  
Global Growth

In 2012, Vietnam?s economy faced great challenges. The world economy experienced more difficulties and complicated upheavals. International trade fell drastically while global growth rate was lower than predicted target, which affected badly the Vietnamese economy because of its full integration into the world economy and large openness. In this context, principal targets set for 2013 are macroeconomic stability, lower inflation rate, higher growth rate, three strategic breakthroughs associated with restructuring of the economy, and a new economic growth model. This paper analyzes obstacles to Vietnam?s economic growth, and offers short-term solutions to bottlenecks and long-term ones to the economic restructuring.

The effect of the financing structure on the return on the market share in Saudi companies An Empirical Study: أثر هيكل التمويل على عائد السهم السوقي في الشركات السعودية: دراسة تطبيقية

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Fatimah Mohammad Asiri
Keyword(s):  
Market Share ◽  
Food Production ◽  
Analytical Approach ◽  
Negative Impact ◽  
Short Term ◽  
Financing Structure ◽  
Time Period ◽  
Comprehensive Survey ◽  
Study Population

The study aimed to identify the influence of the financing structure on the return of the market share in Saudi corporations/companies. The study applied the descriptive-analytical approach, and the study population consisted of some joint-stock companies in the Saudi stock market, where the study sample consisted of (75) companies in five productive sectors where concentration was made on the following sectors: (basic materials, long-term commodities, energy, food production, capital goods). Method of the comprehensive survey was used for all companies. The data was analyzed using the Panel Data method through the STATA program. The study concluded several findings, the most important of which are that short-term debt (liabilities) have a negative impact on the return on the market share, as increasing short debts (liabilities) lead to a decrease in the return on the market share, and that long-term debt (liabilities) have no effect on the return on the market share, and equity has a negative impact on the return on the market share, as the increase in financing through equity leads to a decrease in the return on the market share. The study recommended the necessity of diversification between sources of financing and not limited to debt and long & short-term liabilities only. It also recommended conducting such a study on other sectors or conducting it on the whole market which may result in improving results, and also recommends expanding the time period more than five years, which may lead to improve results.

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