scholarly journals Diversity in antibody titer at an average of 87 days after the second dose of BNT162b2 mRNA coronavirus disease 2019 vaccine: data from a predominantly elderly population in a practice in Tokyo

Author(s):  
Yasuko Fuse-Nagase ◽  
Mitsuo Nagase

It is very important for the elderly, who tend to have serious COVID-19 infection and high mortality rates, to maintain sufficient immunity. We reviewed the medical charts of predominantly elderly population to obtain the data on serum anti-SARS-CoV-2S antibody titer after complete vaccination with the BNT162b2 mRNA vaccine (two doses) and evaluated the background factors associated with the titer. We enrolled 230 participants (101 men and 129 women). Their average age was 71.9 (SD 12.5) years, and median was 72 years. The anti-SARS-CoV-2S antibody titer varied from 0.55 U/mL to 4920 U/mL. We found that the value of the titer varied widely. The value of the titer was negatively associated with age, alcohol consumption, time elapsed from second vaccine dose, and use of immunosuppressive medication. The result that the titer was negatively associated with aging suggests that the timing of additional shot should be carefully determined especially among elderly population.

Author(s):  
Shamsul Azhar Shah ◽  
Nazarudin Safian ◽  
Saharuddin Ahmad ◽  
Wan Abdul Hannan Wan Ibadullah ◽  
Zulkefley bin Mohammad ◽  
...  

Happiness is an essential component to experience healthy ageing. Hence, understanding the factors that contribute to happiness is important. This study aimed to determine the factors associated with happiness among the elderly population in Malaysia. In this study, 1204 respondents were recruited from urban and rural areas in Selangor. A face-to-face interview was conducted using the Bahasa Malaysia version of the Japan Gerontological Evaluation Study questionnaire. The inclusion criteria include Malaysians who are 60-years old and above and can converse in the Malaysian language. Those who encounter less than seven scores for the Abbreviated Mental Test were excluded from the study. Among the 1204 respondents, 953 (79.2%) were happy. Sociodemographic characteristics showed that being a men, age of 60 to 74 years, and living in urban areas were significantly associated with happiness. A logistic regression model showed that locality (aOR 1.61), income category (Bottom 40% aOR 0.49; Middle-class group 40% aOR 1.40), social engagement (active aOR 1.77; less active aOR 1.25), receiving emotional support (aOR 2.11) and handgrip strength (aOR 1.02) were significantly associated with happiness. Thus, ensuring the elderly population in receiving emotional support and active social engagement among them can enhance their happiness level.


2020 ◽  
Vol 8 (1) ◽  
pp. e001355
Author(s):  
Silvia Cascini ◽  
Nera Agabiti ◽  
Marina Davoli ◽  
Luigi Uccioli ◽  
Marco Meloni ◽  
...  

IntroductionThe aim of the study was to identify the sociodemographic and clinical factors associated with death after the first lower-extremity amputation (LEA), minor and major separately, using data from regional health administrative databases.Research design and methodsWe carried out a population-based cohort study including patients with diabetes residing in the Lazio region and undergoing a primary amputation in the period 2012–2015. Each individual was followed up for at least 2 years. Kaplan-Meier analysis was used to evaluate long-term survival; Cox proportional regression models were applied to identify factors associated with all-cause mortality.ResultsThe cohort included 1053 patients, 72% were male, 63% aged ≥65 years, and 519 (49%) died by the end of follow-up. Mortality rates at 1 and 4 years were, respectively, 33% and 65% for major LEA and 18% and 45% for minor LEA. Significant risk factors for mortality were age ≥65, diabetes-related cardiovascular complications, and chronic renal disease for patients with minor LEA, and age ≥75 years, chronic renal disease and antidepressant drug consumption for subjects with major LEA.ConclusionsThe present study confirms the high mortality rates described in patients with diabetes after non-traumatic LEA. It shows differences between minor and major LEA in terms of mortality rates and related risk factors. The study highlights the role of depression as specific risk factor for death in patients with diabetes after major LEA and suggests including its definition and management in strategies to reduce the high mortality rate observed in this group of patients.


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Man Kumar Tamang ◽  
Uday Narayan Yadav ◽  
Hassan Hosseinzadeh ◽  
Bharat Kafle ◽  
Girish Paudel ◽  
...  

2020 ◽  
Vol 34 ◽  
Author(s):  
Valmir Vanderlei Gomes Filho ◽  
Rafael da Silveira Moreira ◽  
Manoelito Ferreira Silva Junior ◽  
Brunna Verna Castro Gondinho ◽  
Denise de Fátima Barros Cavalcante ◽  
...  

Author(s):  
Carmelo Gómez Martínez ◽  
Elena Carrasco Martínez ◽  
Inmaculada Martínez Escámez ◽  
Pedro Andreo Muñoz

Within the elderly population, the specific circumstances that some of the elderly find themselves due to certain socio-cultural factors make them more likely to be abused while residing in assisted living residences, due to the facts that the abuse is coming from the organisation it is unlikely to be reported, or brought to the attention of others, making it difficult to detect and, as a result, an issue not often discussed. We intend to investigate these possibilities; however, due to lack of information on this subject, we aim to address this issue by investigating the number of elderly people living in nursing homes who have suffered abuse due to agents outside of the organisation, such as the family, other residents and Friends. A brief questionnaire was created on an Excel Spreadsheet for the collection of data for this study, these questionnaires where then passed on the social workers of 4 assisted living residences, in the geographical scope of the Murcia region. The data collected correspond to the time period between January and December 2013. The results lead us to believe that the principal risk factors associated with this type of abuse is being a woman, a widow and with and age of about 80 years. Psychological abuse from family members was the most frequently reported type of abuse in the study.


2020 ◽  
Author(s):  
Lubna Naz ◽  
Umesh Ghimire ◽  
Abida Zainab

Abstract Background In Pakistan, healthcare system is facing unprecedented challenges to deal with the healthcare demand of the growing ageing population. Using a conceptual framework, this study aims to analyze the factors associated with the utilization of healthcare services in private and public hospitals by the elderly population. Methods This study used a sample of 5,319 individuals aged 60 and above extracted from the Pakistan Social and Living Standards Measurement Survey 2014-15. We followed the Anderson’s Behavioral model of healthcare utilization. The behavioral factors, including predisposing, enabling and need factors, associated with the use of healthcare care were analyzed using exploratory data analysis and binary logistic regressions. The utilization of healthcare service in the study refers to the visits to private and government hospitals. Results Out of total 5,319 participants around three-fourth or 72.4% of participants visited private hospitals for their healthcare needs. Multivariate analysis showed that older age-group (80 years and above) and participants from urban were 1.35 and 1.53 times more likely to avail healthcare service in private hospitals, respectively. The elderly persons from Khyber Pakhtunkhwa were three times (AOR: 3.29, 95%CI 2.5-4.8) more likely to visit government hospitals than their peers in Punjab. Participants who attended school (AOR: 1.21, 95%CI 0.82-1.31) were more likely to utilize healthcare service in private hospitals. Elders from rich (AOR: 1.04, 95%CI 0.84-1.13) and richest (AOR: 1.29, 95%CI 0.89-1.87) wealth quintiles were more likely to use healthcare in private hospitals. The likelihood of the utilization of healthcare service in private hospitals was 1.7 times higher for three or more consulting visits than the single visit, and 1.5 times higher in the public hospital. Conclusions Our findings underscore a dire need for expanding outreach of healthcare services for elderly population. It calls for an effective implementation of policies which aim at improving equitable access to private healthcare services, and upgrading of government hospitals Moreover, the knowledge generated through this research may be employed to make social protection programs more responsive to age-related healthcare needs, and focused on caregiving for elderly living without spouse.


2012 ◽  
Vol 55 (3) ◽  
pp. 625-631 ◽  
Author(s):  
Pilar Jürschik ◽  
Carmen Nunin ◽  
Teresa Botigué ◽  
Miguel Angel Escobar ◽  
Ana Lavedán ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lubna Naz ◽  
Umesh Ghimire ◽  
Abida Zainab

Abstract Background In Pakistan, health system is facing unprecedented challenges to deal with the healthcare demand of the growing ageing population. Using conceptual framework, this study aims to analyze the factors associated with the utilization of healthcare services in private and public hospitals by the elderly population. Methods This study used a sample of 5319 individuals aged 60 and above extracted from the Pakistan Social and Living Standards Measurement Survey 2014–15. We followed the Anderson’s Behavioral model of healthcare utilization. The behavioral factors, including predisposing, enabling and need factors, associated with the use of healthcare care were analyzed using exploratory data analysis and binary logistic regressions. The utilization of healthcare service in the study refers to the visits to private and government hospital. Results Out of total 5319 participants around three-fourth or 72.4% of participants visited private hospitals for their healthcare needs. Multivariate analysis showed that older age-group (80 years and above) and participants from urban were 1.35 and 1.53 times more likely to avail healthcare service in private hospitals, respectively. The elderly persons from Khyber Pakhtunkhwa were three times (AOR: 3.29, 95%CI 2.5–4.8) more likely to visit government hospitals than their peers in Punjab. Participants who attended school (AOR: 1.21, 95%CI 0.82–1.31) were more likely to utilize healthcare service in private hospitals. Elders from rich (AOR: 1.04, 95%CI 0.84–1.13) and richest (AOR: 1.29, 95%CI 0.89–1.87) wealth quintiles were more likely to use healthcare in private hospitals. The likelihood of the utilization of healthcare service in private hospitals was 1.7 times higher for three or more consulting visits than the single visit, and 1.5 times higher in the public hospital. Conclusions Our findings underscore a dire need for expanding the outreach of healthcare services for the elderly population. It calls for effective implementation of policies which aim at improving equitable access to private healthcare services, and upgrading of government hospitals Moreover, the knowledge generated through this research may be employed to make social protection programs more responsive to age-related healthcare needs, and focused on caregiving for elderly living without spouse.


2020 ◽  
Author(s):  
Lubna Naz ◽  
Umesh Ghimire ◽  
Abida Zainab

Abstract BackgroundIn Pakistan, health system is facing unprecedented challenges to deal with the healthcare demand of the growing ageing population. Using conceptual framework, this study analyzes the factors associated with outpatient services utilization by the elderly population Methods This study used a sample of 5,319 individuals aged 60 and above extracted from the Pakistan Social and Living Standards Measurement Survey 2014-15. We modified the Anderson’s Behavioral model to accommodate available information on the elderly healthcare utilization. The behavioral factors, including predisposing, enabling and need factors, associated with the use of outpatient service were analyzed using exploratory data analysis and binary logistic regressions. The utilization of outpatient service in the study refers to the visits to private and government hospitals.ResultsOut of total 5,319 participants, 72.4% of participants visited outpatient services in private hospitals for their healthcare needs. Multivariate analysis showed that older age-group (80 years and above) and participants from urban were 35% and 53% times more likely to visit outpatient services in private hospitals, respectively. The elderly persons from Khyber Pakhtunkhwa were three times (AOR: 3.29, CI 2.5-4.8) more likely to visit government hospitals than their peers in Punjab. Participants who attended school (AOR: 1.21, CI 0.82-1.31) were more likely to utilize outpatient service in private hospitals. Elders from rich (AOR: 1.04, CI 0.84-1.13) and richest (AOR: 1.29, CI 0.89-1.87) wealth quintiles were more likely to visit private hospitals. The likelihood of the utilization of outpatient service in private hospitals increased by 17% with the increase in the frequency of consultation by three times and more.ConclusionsOur findings underscore a dire need for expanding the outreach of healthcare services, particularly government hospital facilities, for the elderly population. Moreover, the knowledge generated through this research may be employed to make particular behavioral interventions in areas, such as, age, caregiving for elderly living without spouse, poor, and elderly without social security or pension, and education.


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