Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations
We present a new, carefully designed and well-annotated dataset of images and image-based profiles of cells that have been treated with chemical compounds and genetic perturbations. Each gene that is perturbed is a known target of at least two compounds in the dataset. The dataset can thus serve as a benchmark to evaluate methods for predicting similarities between compounds and between genes and compounds, measuring the effect size of a perturbation, and more generally, learning effective representations for measuring cellular state from microscopy images. Advancements in these applications can accelerate the development of new medicines.
1978 ◽
Vol 36
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pp. 278-279
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1972 ◽
Vol 30
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pp. 448-449
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Vol 42
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pp. 498-499
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Vol 45
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pp. 180-181
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Vol 38
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pp. 340-341
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Vol 8
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pp. 18-24
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2006 ◽
Vol 20
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pp. 186-194
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